A M Leroi
Affiliation: Imperial College
- The scale independence of evolutionA M Leroi
Department of Biology, Imperial College at Silwood Park, Ascot, Berks, UK
Evol Dev 2:67-77. 2000..Finally, I ask what must be known if we are to understand the ultimate causes of molecular and developmental diversity...
- Cancer selectionArmand M Leroi
Department of Biological Sciences, Imperial College London, Silwood Park Campus, Ascot, Berks SL5 7PY, UK
Nat Rev Cancer 3:226-31. 2003....
- A power law for cellsR B Azevedo
Department of Biology, Imperial College of Science, Technology, and Medicine, Silwood Park, Ascot, Berkshire SL5 7PY, United Kingdom
Proc Natl Acad Sci U S A 98:5699-704. 2001..We also identify taxa in which the precision of developmental control appears to have evolved. We propose that the scale independence of relative cell number variability is maintained by natural selection...
- Origins and evolution of a transmissible cancerClare A Rebbeck
Department of Biology, Imperial College London, Berks, United Kingdom
Evolution 63:2340-9. 2009....
- Testing life-history pleiotropy in Caenorhabditis elegansC G Knight
Department of Biology, Imperial College at Silwood Park, Ascot, Berkshire, United Kingdom
Evolution 55:1795-804. 2001..The evolutionary origin of these QTLs, possible candidate loci, and the significance for life-history evolution are discussed...
- Evolution of germ-line signals that regulate growth and aging in nematodesMavji N Patel
Department of Biological Science, Imperial College at Silwood Park, Ascot, Berks SL5 7PY, United Kingdom
Proc Natl Acad Sci U S A 99:769-74. 2002..Some species have both signals; others have just one or the other. We suggest that variation in germ-line signaling contributes to body size and life-history diversity in the nematodes...
- Spontaneous mutational variation for body size in Caenorhabditis elegansRicardo B R Azevedo
Department of Biology, Imperial College, Berks SL5 7PY, United Kingdom
Genetics 162:755-65. 2002..We observed a strongly asymmetrical response to selection of a magnitude consistent with the input of mutational variance observed in the MA experiment...
- A Caenorhabditis elegans TGF-beta, DBL-1, controls the expression of LON-1, a PR-related protein, that regulates polyploidization and body lengthKiyokazu Morita
Department of Developmental Biology, National Institute for Basic Biology, The Graduate University for Advanced Studies, Okazaki 444 8585, Japan
EMBO J 21:1063-73. 2002..Consistent with this, LON-1 is expressed mainly in the larval and adult hypodermis and has dose-dependent effects on body length associated with changes in hypodermal ploidy, but not hypodermal cell proliferation...