Research Topics
| Marina K KuimovaSummaryAffiliation: Imperial College Country: UK Publications
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Detail Information
Publications
Determination of the triplet state energies of a series of conjugated porphyrin oligomersMarina K Kuimova
Chemistry Department, Imperial College London, Exhibition Road, SW7 2AZ, UK
Photochem Photobiol Sci 6:675-82. 2007..Thus the conjugated porphyrin dimer is the most promising core structure for PDT applications via multiphoton excitation...- Picosecond time-resolved infrared study of 2-aminopurine ionisation in solutionMarina K Kuimova
School of Chemistry, University of Nottingham, University Park, Nottingham, UK
Photochem Photobiol Sci 6:949-55. 2007..DFT calculations (EDF1/6-31+G*) were used to support the assignment of the intermediates observed in these spectroscopic experiments... 
Mapping viscosity in cells using molecular rotorsMarina K Kuimova
Chemistry Department, Imperial College London, Exhibition Road, London SW7 2AZ, UK
Phys Chem Chem Phys 14:12671-86. 2012..Finally, it is discussed how the major advantage of molecular rotor imaging, fast signal acquisition, can be used to monitor changing viscosity during dynamic biological processes within cells, such as photoinduced cell death...- Molecular rotors image intracellular viscosityMarina K Kuimova
Chemistry Department, Imperial College, South Kensington SW7 2AZ, London, UK
Chimia (Aarau) 66:159-65. 2012..We have illustrated this advantage by monitoring changes in intracellular viscosity during photodynamic therapy, which is a clinically utilised modality for the treatment of neoplastic disease... - Intramolecular rotation in a porphyrin dimer controls singlet oxygen productionMarina K Kuimova
Chemistry Department, Imperial College London, Exhibition Road, SW7 2AZ, UK
J Am Chem Soc 131:7948-9. 2009..This property may be beneficial for many applications requiring the controlled release of an oxidizing species, e.g., microfabrication and singlet oxygen-mediated cell death... - Imaging intracellular viscosity of a single cell during photoinduced cell deathMarina K Kuimova
Chemistry Department, Imperial College London, Exhibition Road, London SW7 2AZ, UK
Nat Chem 1:69-73. 2009..Using these tools, we provide insight into the dynamics of diffusion in cells, which is pertinent to drug delivery, cell signalling and intracellular mass transport... - Molecular rotor measures viscosity of live cells via fluorescence lifetime imagingMarina K Kuimova
Chemistry Department, Imperial College London, Exhibition Road, SW7 2AZ, UK
J Am Chem Soc 130:6672-3. 2008..The high viscosity of intracellular compartments is likely to play an important role in vital intracellular processes, including the rate of diffusion of reactive oxygen species, causing programmed cell destruction... - Singlet oxygen in a cell: spatially dependent lifetimes and quenching rate constantsMarina K Kuimova
Chemistry Department, Imperial College London, Exhibition Road, London SW7 2AZ, UK
J Am Chem Soc 131:332-40. 2009..Thus, despite a relatively long intracellular lifetime, singlet oxygen does not diffuse a great distance from its site of production. This is a consequence of an apparent intracellular viscosity that is comparatively large... - Photophysical properties and intracellular imaging of water-soluble porphyrin dimers for two-photon excited photodynamic therapyMarina K Kuimova
Chemistry Department, Imperial College London, Exhibition Road, London SW72AZ, UK
Org Biomol Chem 7:889-96. 2009..Analysis of the photophysical parameters and intracellular imaging data indicates that these dimers are promising candidates for one-photon and two-photon excited PDT... - Fluorescence characterisation of multiply-loaded anti-HER2 single chain Fv-photosensitizer conjugates suitable for photodynamic therapyMarina K Kuimova
Chemistry Department, Imperial College London, Exhibition Road, UK
Photochem Photobiol Sci 6:933-9. 2007..The present study highlights the usefulness of photosensitizer immunoconjugates with scFvs for targeted PDT... - Fluorescence anisotropy of molecular rotorsJames A Levitt
Department of Physics, King s College London, Strand, London, WC2R 2LS, UK
Chemphyschem 12:662-72. 2011.... 
Monitoring the direct and indirect damage of DNA bases and polynucleotides by using time-resolved infrared spectroscopyMarina K Kuimova
School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom
Proc Natl Acad Sci U S A 103:2150-3. 2006..The ability to use time-resolved infrared spectroscopy in this way paves the way for developing solution-phase studies to investigate both direct and indirect radiation chemistry of DNA...- Novel photosensitisers derived from pyropheophorbide-a: uptake by cells and photodynamic efficiency in vitroIoanna Stamati
Division of Cell and Molecular Biology, Faculty of Natural Sciences, Imperial College London, Exhibition Road, SW7 2AZ, UK
Photochem Photobiol Sci 9:1033-41. 2010..These studies highlight the underlying factors behind creating more potent photosensitisers through synthetic manipulation... - Picosecond time-resolved infrared spectroscopic investigation into electron localisation in the excited states of Re(i) polypyridyl complexes with bridging ligandsMarina K Kuimova
School of Chemistry, University of Nottingham, University Park, Nottingham, UK
Photochem Photobiol Sci 5:82-7. 2006..The nu(CO) bands of the adjacent Re centre are affected by the reduction of the bridging ligand. On the IR timescale the excited state structure is best formulated as [Cl(CO)3Re(II)(micro-ppbMe2 *-)Re(I)(CO)3Cl]... - Chemical imaging of live cancer cells in the natural aqueous environmentMarina K Kuimova
Department of Chemistry, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom
Appl Spectrosc 63:164-71. 2009....