Masud Husain

..These proposals accord with recent electrophysiological and functional imaging data, demonstrating posterior parietal involvement in the retention of target locations across saccades...

..These findings demonstrate that an impairment in SWM capacity can contribute to the neglect syndrome in patients with stroke involving regions within the right parietal lobe and insula...

..When combined with a spatial bias to the right, such deficits might explain why many neglect patients often re-examine rightward locations, at the expense of items to their left...

..When his recovery was tracked over several months, his SWM deficit and left neglect showed concurrent improvements. We argue that impaired SWM may be one important component of the visual neglect syndrome...

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..Future studies of possible rehabilitative impact from prisms upon neglect may need to consider carefully how to measure prism adaptation per se, separately from any impact of such adaptation upon manifestations of neglect...

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..The results suggest that neuropharmacological targeting of intact frontal areas might be one way to enhance cognitive function after damage to posterior brain regions in selected individuals...

..Finally, manipulating the visual salience of found targets altered the degree of neglect, but not revisit rates. Space exploration appears to be modulated both by the ability to keep track of spatial locations and by stimulus salience...

..Instead, our results implicate the angular gyrus and parahippocampal region in this role...

..These results demonstrate that visual working memory consists of a common resource distributed dynamically across the visual scene, with no need to invoke an upper limit on the number of objects represented...

..Instead, we consider a novel perspective in which the primary function of spatial remapping is to support three key nonperceptual processes: action control, sensorimotor adaptation and spatial memory...

..Guanfacine may prove to be a useful tool in the treatment of disorders of attention associated with neurological conditions...

..These results provide evidence of a causal role for the SEF in oculomotor control in the absence of visual feedback...

..In this review, we discuss the evidence for such a proposal and suggest that a better understanding of human parietal syndromes may emerge from considering both the spatial and non-spatial functions of this region...

..However, theories regarding their function vary widely. This Review brings together the data regarding the supplementary motor regions, highlighting outstanding issues and providing new perspectives for understanding their functions...

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..Recording continuous grip force, as here, provides a sensitive way to measure coactivated responses in affordance tasks...

..Finally, we consider how one supposedly crucial role of attention--that of binding features which belong to an object--might operate so that object representations are veridically maintained and remapped across eye movements...

..This can then overcome competition between stimuli presented on opposite sides of the body midline, thus modulating extinction...

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..We suggest that this task may be useful in probing deficits in voluntary action in pathological states...

..This proof-of-concept study suggests a beneficial role of dopaminergic modulation on visual search and selective attention in patients with hemispatial neglect following stroke...

..Here we discuss therapeutic interventions that have been used across a range of conditions, highlighting common themes both in the nature of the attention deficits and the strategies employed to treat them...

..This review discusses recent studies that have implications for potential neuropharmacological interventions which target cognitive deficits resulting from traumatic brain injury or stroke...

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..The article focuses on hemispatial neglect as a common and difficult to manage problem in clinical practice...

..Neurons in medial frontal cortex have been found to distinguish between whether an animal or its partner is responding on a turn-taking task, but are they really the basis of a social learning mechanism?..

..They also suggest that tactile extinction can be caused by attenuation rather than elimination of somatosensory responses in the damaged hemisphere, with an underlying deficit even on unilateral trials...

..Possible reasons for the discrepancies between our results and neuroimaging studies are discussed. We conclude that our findings urge caution against using functional imaging as the sole method of establishing cognitive neuroanatomy...

..Our findings demonstrate a spatial and temporal gradient of attention. The results are discussed with respect to current models of visual processing in visual neglect...

..These findings extend recent observations on visual extinction, suggesting distinct neural correlates for conscious and unconscious perception...

..These findings imply that the SEF and SMA mediate automatic effector-specific suppression of motor plans. This automatic mechanism may contribute to the participation of these areas in the voluntary control of action...

..Thus, the action control deficits in neglect may be conceptualised as a range of impairments affecting multiple stages in the visuomotor control process...

..These results suggest implicit but not explicit memory for extinguished visual stimuli in parietal patients...

..We propose instead that the IPL+STG has a top-down control role, contributing to the functions of both dorsal and ventral visual systems...

..These findings demonstrate how the effective visual field is dynamically modulated by the deployment of attention in health and, more severely, following right parieto-temporal damage...

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..They lead to poor outcome and frequently coexist. Here we focus on recent progress in the understanding of the mechanisms underlying these disorders and potential therapeutic advances...

..The hypothesis is discussed in relation to recent disconnectionist accounts of optic ataxia...

..These findings demonstrate relatively intact priming of visual search by color and location in patients with right parietal damage, and also reveal that location priming may differ from color priming in requiring awareness...

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..The critical role played by the right ventrolateral region in cognitive tasks may arise due to an additional functional specialization for the monitoring and updating of task rules...

..We discuss these findings in the context of a unified framework of pre-SMA function, and explore the degree to which extant data on this region can be explained by this function alone...

..These findings represent a clear dissociation between visual orienting of attention and gaze...

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..We propose a functional architecture of human medial frontal cortex that incorporates the generation of action plans and the resolution of conflict...

..The proportion of resources allocated to each item determines the precision with which it is remembered, a relation that we show is governed by a simple power law, allowing quantitative estimates of resource distribution in a scene...

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..Furthermore, signals recorded from the superior colliculus showed the reverse pattern of responses, consistent with a direct inhibitory influence of IPS on SC...

..We therefore propose that it should be the method of choice for normalizing images of focally lesioned brains...