T Deirdre Hollingsworth

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi request reprint HIV-1 transmission, by stage of infection
    T Deirdre Hollingsworth
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom
    J Infect Dis 198:687-93. 2008
  2. pmc Mitigation strategies for pandemic influenza A: balancing conflicting policy objectives
    T Deirdre Hollingsworth
    MRC Centre for Outbreak Control and Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Comput Biol 7:e1001076. 2011
  3. pmc Frequent travelers and rate of spread of epidemics
    T Deirdre Hollingsworth
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease and Epidemiology, Imperial College London, London, United Kingdom
    Emerg Infect Dis 13:1288-94. 2007
  4. pmc Estimating the public health impact of the effect of herpes simplex virus suppressive therapy on plasma HIV-1 viral load
    Rebecca F Baggaley
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    AIDS 23:1005-13. 2009
  5. doi request reprint Virulence and pathogenesis of HIV-1 infection: an evolutionary perspective
    Christophe Fraser
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London SW7 2AZ, UK
    Science 343:1243727. 2014
  6. pmc HIV-1 transmitting couples have similar viral load set-points in Rakai, Uganda
    T Deirdre Hollingsworth
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Pathog 6:e1000876. 2010
  7. pmc Pandemic potential of a strain of influenza A (H1N1): early findings
    Christophe Fraser
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, Faculty of Medicine, Norfolk Place, London W2 1PG, UK
    Science 324:1557-61. 2009
  8. pmc Gradual acquisition of immunity to severe malaria with increasing exposure
    Jamie T Griffin
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London W2 1PG, UK
    Proc Biol Sci 282:20142657. 2015
  9. pmc Heterosexual HIV-1 infectiousness and antiretroviral use: systematic review of prospective studies of discordant couples
    Rebecca F Baggaley
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, United Kingdom
    Epidemiology 24:110-21. 2013
  10. pmc Variation in HIV-1 set-point viral load: epidemiological analysis and an evolutionary hypothesis
    Christophe Fraser
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London W2 1PG, United Kingdom
    Proc Natl Acad Sci U S A 104:17441-6. 2007

Detail Information

Publications14

  1. doi request reprint HIV-1 transmission, by stage of infection
    T Deirdre Hollingsworth
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom
    J Infect Dis 198:687-93. 2008
    ....
  2. pmc Mitigation strategies for pandemic influenza A: balancing conflicting policy objectives
    T Deirdre Hollingsworth
    MRC Centre for Outbreak Control and Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Comput Biol 7:e1001076. 2011
    ..These analyses highlight the need for more precise statements of policy objectives and their assumed consequences when planning and implementing strategies to mitigate the impact of an influenza pandemic...
  3. pmc Frequent travelers and rate of spread of epidemics
    T Deirdre Hollingsworth
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease and Epidemiology, Imperial College London, London, United Kingdom
    Emerg Infect Dis 13:1288-94. 2007
    ....
  4. pmc Estimating the public health impact of the effect of herpes simplex virus suppressive therapy on plasma HIV-1 viral load
    Rebecca F Baggaley
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    AIDS 23:1005-13. 2009
    ..Our aim was to estimate the population-level impact of suppressive therapy on female-to-male HIV-1 sexual transmission...
  5. doi request reprint Virulence and pathogenesis of HIV-1 infection: an evolutionary perspective
    Christophe Fraser
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London SW7 2AZ, UK
    Science 343:1243727. 2014
    ..We propose conceptual models that reconcile adaptive evolution at both levels of selection. Evolutionary analysis provides new insight into HIV pathogenesis. ..
  6. pmc HIV-1 transmitting couples have similar viral load set-points in Rakai, Uganda
    T Deirdre Hollingsworth
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Pathog 6:e1000876. 2010
    ..The most parsimonious explanation is that this is due to shared characteristics of the transmitted virus, a finding which sheds light on both the role of viral factors in HIV-1 pathogenesis and on the evolution of the virus...
  7. pmc Pandemic potential of a strain of influenza A (H1N1): early findings
    Christophe Fraser
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, Faculty of Medicine, Norfolk Place, London W2 1PG, UK
    Science 324:1557-61. 2009
    ..Transmissibility is therefore substantially higher than that of seasonal flu, and comparable with lower estimates of R0 obtained from previous influenza pandemics...
  8. pmc Gradual acquisition of immunity to severe malaria with increasing exposure
    Jamie T Griffin
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London W2 1PG, UK
    Proc Biol Sci 282:20142657. 2015
    ..Careful monitoring of the decline in immunity associated with reduced transmission will therefore be needed to ensure rebound epidemics of severe and fatal malaria are avoided. ..
  9. pmc Heterosexual HIV-1 infectiousness and antiretroviral use: systematic review of prospective studies of discordant couples
    Rebecca F Baggaley
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, United Kingdom
    Epidemiology 24:110-21. 2013
    ....
  10. pmc Variation in HIV-1 set-point viral load: epidemiological analysis and an evolutionary hypothesis
    Christophe Fraser
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London W2 1PG, United Kingdom
    Proc Natl Acad Sci U S A 104:17441-6. 2007
    ..We discuss how this evolutionary hypothesis can be tested, review the evidence available to date, and highlight directions for future research...
  11. pmc The potential contribution of mass treatment to the control of Plasmodium falciparum malaria
    Lucy C Okell
    Department of Infectious Disease Epidemiology, MRC Centre for Outbreak Analysis and Modeling, Imperial College London, London, United Kingdom
    PLoS ONE 6:e20179. 2011
    ..The benefits of mass treatment need to be carefully weighed against the risks of increasing drug selection pressure...
  12. doi request reprint Controlling infectious disease outbreaks: Lessons from mathematical modelling
    T Deirdre Hollingsworth
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London W2 1PG, UK
    J Public Health Policy 30:328-41. 2009
    ..They are illustrated using examples from the 2003 severe acute respiratory syndrome outbreak, which was brought under control within a year, and from pandemic influenza planning, where mathematical models have been used extensively...
  13. pmc Brief report: HIV-1 transmissions during asymptomatic infection: exploring the impact of changes in HIV-1 viral load due to coinfections
    Rebecca F Baggaley
    Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom Mathematics Institute, University of Warwick, Coventry, United Kingdom School of Life Sciences, University of Warwick, Coventry, United Kingdom and Department of Clinical Sciences, Liverpool School of Hygiene and Tropical Medicine, Liverpool, United Kingdom
    J Acquir Immune Defic Syndr 68:594-8. 2015
    ..For most HIV-1 coinfections, the duration of a single infection is too short and/or the associated PVL elevation is too modest to contribute substantially to onward HIV-1 transmission. ..
  14. pmc How effective is school-based deworming for the community-wide control of soil-transmitted helminths?
    Roy M Anderson
    London Centre for Neglected Tropical Diseases, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
    PLoS Negl Trop Dis 7:e2027. 2013
    ..However, the impact of school-based deworming on transmission in the wider community remains unclear...