Alister J Hart

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi The painful metal-on-metal hip resurfacing
    A J Hart
    Department of Radiology Imperial College, Charing Cross Hospital, London, UK
    J Bone Joint Surg Br 91:738-44. 2009
  2. doi The chemical form of metallic debris in tissues surrounding metal-on-metal hips with unexplained failure
    Alister J Hart
    Department of Orthopaedic Surgery, Imperial College and Imperial College Healthcare NHS Trust, Charing Cross Hospital Campus, Fulham Palace Road, London W68RF, UK
    Acta Biomater 6:4439-46. 2010
  3. doi Which factors determine the wear rate of large-diameter metal-on-metal hip replacements? Multivariate analysis of two hundred and seventy-six components
    A J Hart
    Department of Musculoskeletal Surgery, Imperial College Charing Cross Hospital Campus, Fulham Palace Road, London, UK
    J Bone Joint Surg Am 95:678-85. 2013
  4. doi Pseudotumors in association with well-functioning metal-on-metal hip prostheses: a case-control study using three-dimensional computed tomography and magnetic resonance imaging
    Alister J Hart
    Department of Orthopaedic Surgery, Charing Cross Hospital Imperial College Healthcare NHS Trust and Imperial College London, Fulham Palace Road, London W6 8RF, United Kingdom
    J Bone Joint Surg Am 94:317-25. 2012
  5. doi Understanding why metal-on-metal hip arthroplasties fail: a comparison between patients with well-functioning and revised birmingham hip resurfacing arthroplasties. AAOS exhibit selection
    Alister J Hart
    Department of Musculoskeletal Surgery, Imperial College London, Charing Cross Hospital Campus, Fulham Palace Road, London W6 8RF, United Kingdom
    J Bone Joint Surg Am 94:e22. 2012
  6. doi Sensitivity and specificity of blood cobalt and chromium metal ions for predicting failure of metal-on-metal hip replacement
    A J Hart
    Imperial College London, Department of Musculoskeletal Surgery, Charing Cross Hospital Campus, Fulham Palace Road, London W6 8RF, UK
    J Bone Joint Surg Br 93:1308-13. 2011
  7. doi The relationship between the angle of version and rate of wear of retrieved metal-on-metal resurfacings: a prospective, CT-based study
    A J Hart
    Department of Musculoskeletal Surgery, Imperial College, London, United Kingdom
    J Bone Joint Surg Br 93:315-20. 2011
  8. ncbi Large ball metal on metal hips obscure cup angle measurement on plain radiographs
    Alister J Hart
    Department of Musculoskeletal Surgery, Imperial College London, Charing Cross Hospital Campus, London, UK
    Hip Int 19:323-9. 2009
  9. doi Circulating levels of cobalt and chromium from metal-on-metal hip replacement are associated with CD8+ T-cell lymphopenia
    A J Hart
    Department of Musculoskeletal Surgery Charing Cross, Imperial College, London, England
    J Bone Joint Surg Br 91:835-42. 2009
  10. ncbi Cup inclination angle of greater than 50 degrees increases whole blood concentrations of cobalt and chromium ions after metal-on-metal hip resurfacing
    A J Hart
    Department of Musculoskeletal Surgery, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, UK
    Hip Int 18:212-9. 2008

Collaborators

Detail Information

Publications22

  1. doi The painful metal-on-metal hip resurfacing
    A J Hart
    Department of Radiology Imperial College, Charing Cross Hospital, London, UK
    J Bone Joint Surg Br 91:738-44. 2009
    ..These three clinically useful investigations can help to determine the cause of failure of the implant, predict the need for future revision and aid the choice of revision prostheses...
  2. doi The chemical form of metallic debris in tissues surrounding metal-on-metal hips with unexplained failure
    Alister J Hart
    Department of Orthopaedic Surgery, Imperial College and Imperial College Healthcare NHS Trust, Charing Cross Hospital Campus, Fulham Palace Road, London W68RF, UK
    Acta Biomater 6:4439-46. 2010
    ..The variety of metallic species may have arisen from corrosion, wear or a combination of both. No evidence of Cr(VI) was seen in the tissues examined...
  3. doi Which factors determine the wear rate of large-diameter metal-on-metal hip replacements? Multivariate analysis of two hundred and seventy-six components
    A J Hart
    Department of Musculoskeletal Surgery, Imperial College Charing Cross Hospital Campus, Fulham Palace Road, London, UK
    J Bone Joint Surg Am 95:678-85. 2013
    ..We sought to understand the variation in wear rates in a large series of retrieved metal-on-metal hip arthroplasty components...
  4. doi Pseudotumors in association with well-functioning metal-on-metal hip prostheses: a case-control study using three-dimensional computed tomography and magnetic resonance imaging
    Alister J Hart
    Department of Orthopaedic Surgery, Charing Cross Hospital Imperial College Healthcare NHS Trust and Imperial College London, Fulham Palace Road, London W6 8RF, United Kingdom
    J Bone Joint Surg Am 94:317-25. 2012
    ....
  5. doi Understanding why metal-on-metal hip arthroplasties fail: a comparison between patients with well-functioning and revised birmingham hip resurfacing arthroplasties. AAOS exhibit selection
    Alister J Hart
    Department of Musculoskeletal Surgery, Imperial College London, Charing Cross Hospital Campus, Fulham Palace Road, London W6 8RF, United Kingdom
    J Bone Joint Surg Am 94:e22. 2012
    ....
  6. doi Sensitivity and specificity of blood cobalt and chromium metal ions for predicting failure of metal-on-metal hip replacement
    A J Hart
    Imperial College London, Department of Musculoskeletal Surgery, Charing Cross Hospital Campus, Fulham Palace Road, London W6 8RF, UK
    J Bone Joint Surg Br 93:1308-13. 2011
    ..Blood metal ions had good discriminant ability to separate failed from well-functioning hip replacements. The MHRA cut-off level of 7 ppb provides a specific test but has poor sensitivity...
  7. doi The relationship between the angle of version and rate of wear of retrieved metal-on-metal resurfacings: a prospective, CT-based study
    A J Hart
    Department of Musculoskeletal Surgery, Imperial College, London, United Kingdom
    J Bone Joint Surg Br 93:315-20. 2011
    ..We were unable to show that excess version of the acetabular component alone or combined with femoral version was associated with an increase in the rate of wear based on our assessment of version using CT...
  8. ncbi Large ball metal on metal hips obscure cup angle measurement on plain radiographs
    Alister J Hart
    Department of Musculoskeletal Surgery, Imperial College London, Charing Cross Hospital Campus, London, UK
    Hip Int 19:323-9. 2009
    ..We have used a metal artefact reduction CT protocol with a 3D imaging software package to overcome this problem and measure cup position relative to the Anterior Pelvic Plane...
  9. doi Circulating levels of cobalt and chromium from metal-on-metal hip replacement are associated with CD8+ T-cell lymphopenia
    A J Hart
    Department of Musculoskeletal Surgery Charing Cross, Imperial College, London, England
    J Bone Joint Surg Br 91:835-42. 2009
    ....
  10. ncbi Cup inclination angle of greater than 50 degrees increases whole blood concentrations of cobalt and chromium ions after metal-on-metal hip resurfacing
    A J Hart
    Department of Musculoskeletal Surgery, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, UK
    Hip Int 18:212-9. 2008
    ..The implication is that metal levels can be minimised with optimal orientation of the acetabular component...
  11. pmc Insufficient acetabular version increases blood metal ion levels after metal-on-metal hip resurfacing
    Alister J Hart
    Department of Orthopaedic Surgery, Imperial College, Charing Cross Hospital Campus, London SW7 2AZ, UK
    Clin Orthop Relat Res 469:2590-7. 2011
    ..Thus the relationship between version and blood metal ions levels has not been resolved...
  12. pmc Revision of metal-on-metal hip arthroplasty in a tertiary center: a prospective study of 39 hips with between 1 and 4 years of follow-up
    Alexander D Liddle
    Department of Orthopaedic Surgery, Imperial College, Charing Cross Hospital, London, UK
    Acta Orthop 84:237-45. 2013
    ..As a result, planning of theater time and resources is difficult, surgery is challenging, and outcomes are often poor. We describe our experience with revision of MOMHA and provide recommendations for management...
  13. pmc Pseudotumors are common in well-positioned low-wearing metal-on-metal hips
    Ashley K Matthies
    Department of Musculoskeletal Surgery, Imperial College London, London, SW7 2AZ, UK
    Clin Orthop Relat Res 470:1895-906. 2012
    ..However, the pathogenesis of these lesions remains unclear. Currently, there is inconsistent evidence regarding the influence of adverse cup position and increased wear in the formation of pseudotumors...
  14. doi Magnetic resonance imaging findings in painful metal-on-metal hips: a prospective study
    Shiraz A Sabah
    Imperial College London, London, UK
    J Arthroplasty 26:71-6, 76.e1-2. 2011
    ..Metal artifact reduction sequence magnetic resonance imaging may be useful to diagnose and monitor at-risk hips but requires validation in well-functioning MOM hips before it can guide clinical decision making...
  15. doi Cobalt from metal-on-metal hip replacements may be the clinically relevant active agent responsible for periprosthetic tissue reactions
    Alister J Hart
    Department of Orthopaedic Surgery, Imperial College and Imperial College Healthcare NHS Trust, Charing Cross Hospital Campus, London, UK
    Acta Biomater 8:3865-73. 2012
    ..There is in vitro evidence that Co is more important than Cr in the inflammatory process, but there are no reported human tissue studies of the analysis of implant-derived metals...
  16. doi A retrieval analysis of explanted Durom metal-on-metal hip arthroplasties
    Ashley K Matthies
    Department of Musculoskeletal Surgery, Imperial College London, London, UK
    Hip Int 21:724-31. 2011
    ..This supports recent clinical findings of high revision rates as a result of acetabular loosening for the Durom metal-on-metal hip system...
  17. doi Chemical speciation of nanoparticles surrounding metal-on-metal hips
    Angela E Goode
    Department of Materials, Imperial College London, London, UK
    Chem Commun (Camb) 48:8335-7. 2012
    ..The majority of debris contained Cr(3+), with trace amounts of oxidised cobalt. A minority phase containing a core of metallic chromium and cobalt was also observed...
  18. doi Native acetabular version: 3D CT analysis 
of the psoas valley
    Humza Tariq Osmani
    Trauma and Orthopaedics Department, Imperial College Charing Cross Hospital, London W6 8RF, UK
    Hip Int 23:274-80. 2013
    ..This adds to our understanding of native bony anatomy, and specifically provides a landmark that 3D CT has demonstrated to be potentially useful in assessing native version...
  19. doi Learning how to resurface cam-type femoral heads with acceptable accuracy and precision: the role of computed tomography-based navigation
    Justin P Cobb
    Department of Orthopaedics, Imperial College London, 5 Devonshire Place, London W1G 6HL, United Kingdom
    J Bone Joint Surg Am 90:57-64. 2008
    ..Three models of cam-type hips of increasing severity were used to assess the efficacy of three systems of instrumentation at delivering the required level of accuracy and precision...
  20. doi Retrieval analysis of 240 metal-on-metal hip components, comparing modular total hip replacement with hip resurfacing
    A Matthies
    Department of Musculoskeletal Surgery, Imperial College London, London, United Kingdom
    J Bone Joint Surg Br 93:307-14. 2011
    ..These findings show that failed metal-on-metal hip resurfacing and modular THRs have similar component wear rates and are both associated with raised pre-revision blood levels of metal ions...
  21. doi Simple isolation method for the bulk isolation of wear particles from metal on metal bearing surfaces generated in a hip simulator test
    Fang Lu
    School of Engineering and Material Science, Queen Mary University of London, London, UK
    J Mater Sci Mater Med 23:891-901. 2012
    ..The present study involved a total of eight steps for the isolation process and a wear particle extraction efficiency of 45% was achieved...
  22. ncbi The palmar locking compression plate is biomechanically comparable to the dorsal pi plate for dorsally comminuted, intraarticular wrist fractures
    A J Hart
    Department of Trauma and Orthopaedic Surgery, Charing Cross Hospital, London, UK
    J Hand Surg Eur Vol 32:388-93. 2007
    ..036). However, the absolute difference was only 0.5 mm. Such a small difference is unlikely to be clinically detectable and, therefore, we conclude that there is no clinically significant difference between the two types of fixation...