Timothy B Hallett

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. pmc Evidence for changes in behaviour leading to reductions in HIV prevalence in urban Malawi
    George Bello
    Ministry of Health, Lilongwe, Malawi
    Sex Transm Infect 87:296-300. 2011
  2. pmc Early HIV Infection in the United States: A Virus's Eye View
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Med 10:e1001569. 2013
  3. doi request reprint A side door into care cascade for HIV-infected patients?
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    J Acquir Immune Defic Syndr 63:S228-32. 2013
  4. pmc Optimal uses of antiretrovirals for prevention in HIV-1 serodiscordant heterosexual couples in South Africa: a modelling study
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, United Kingdom
    PLoS Med 8:e1001123. 2011
  5. pmc Estimating the risk of HIV transmission from homosexual men receiving treatment to their HIV-uninfected partners
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Sex Transm Infect 87:17-21. 2011
  6. pmc Measuring and correcting biased child mortality statistics in countries with generalized epidemics of HIV infection
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, London, W2 1PG, England
    Bull World Health Organ 88:761-8. 2010
  7. pmc Will circumcision provide even more protection from HIV to women and men? New estimates of the population impact of circumcision interventions
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Sex Transm Infect 87:88-93. 2011
  8. doi request reprint The role of testing and counselling for HIV prevention and care in the era of scaling-up antiretroviral therapy
    T B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, Norfolk Place, London, UK
    Epidemics 1:77-82. 2009
  9. pmc Estimating the HIV incidence rate: recent and future developments
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    Curr Opin HIV AIDS 6:102-7. 2011
  10. pmc Estimating the resources required in the roll-out of universal access to antiretroviral treatment in Zimbabwe
    T B Hallett
    School of Public Health, Imperial College London, London, UK
    Sex Transm Infect 87:621-8. 2011

Detail Information

Publications46

  1. pmc Evidence for changes in behaviour leading to reductions in HIV prevalence in urban Malawi
    George Bello
    Ministry of Health, Lilongwe, Malawi
    Sex Transm Infect 87:296-300. 2011
    ..At the epicentre of the HIV epidemic in Eastern Africa, HIV prevalence has appeared to stabilise in most countries. However, there are indications that the HIV epidemic in Malawi has recently declined...
  2. pmc Early HIV Infection in the United States: A Virus's Eye View
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Med 10:e1001569. 2013
    ..Tim Hallett reflects on the practical significance of new research by Erik Volz and colleagues on the influence of early HIV infection on disease epidemic dynamics. Please see later in the article for the Editors' Summary. ..
  3. doi request reprint A side door into care cascade for HIV-infected patients?
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    J Acquir Immune Defic Syndr 63:S228-32. 2013
    ..With these insights, it may be possible to considerably strengthen the impact of ART programs...
  4. pmc Optimal uses of antiretrovirals for prevention in HIV-1 serodiscordant heterosexual couples in South Africa: a modelling study
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, United Kingdom
    PLoS Med 8:e1001123. 2011
    ..Earlier ART and PrEP might both reduce HIV-1 transmission in this group, but the merits and synergies of these different approaches have not been analyzed...
  5. pmc Estimating the risk of HIV transmission from homosexual men receiving treatment to their HIV-uninfected partners
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Sex Transm Infect 87:17-21. 2011
    ..To determine how the risk of HIV transmission from homosexual men receiving antiretroviral treatment is related to patterns of patient monitoring and condom use...
  6. pmc Measuring and correcting biased child mortality statistics in countries with generalized epidemics of HIV infection
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, London, W2 1PG, England
    Bull World Health Organ 88:761-8. 2010
    ....
  7. pmc Will circumcision provide even more protection from HIV to women and men? New estimates of the population impact of circumcision interventions
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Sex Transm Infect 87:88-93. 2011
    ..However, these projections need revision to incorporate new data on the effect of male circumcision on the risk of acquiring and transmitting HIV...
  8. doi request reprint The role of testing and counselling for HIV prevention and care in the era of scaling-up antiretroviral therapy
    T B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, Norfolk Place, London, UK
    Epidemics 1:77-82. 2009
    ..HIV Testing and Counselling (TC) programmes are being scaled-up as part of efforts to provide universal access to antiretroviral treatment (ART)...
  9. pmc Estimating the HIV incidence rate: recent and future developments
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    Curr Opin HIV AIDS 6:102-7. 2011
    ..To describe the needs for information on the rate of new HIV infections (incidence) in epidemics and review developments in various methods for its estimation...
  10. pmc Estimating the resources required in the roll-out of universal access to antiretroviral treatment in Zimbabwe
    T B Hallett
    School of Public Health, Imperial College London, London, UK
    Sex Transm Infect 87:621-8. 2011
    ..To develop projections of the resources required (person-years of drug supply and healthcare worker time) for universal access to antiretroviral treatment (ART) in Zimbabwe...
  11. pmc Estimates of HIV incidence from household-based prevalence surveys
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    AIDS 24:147-52. 2010
    ..To estimate HIV incidence in the general population in countries where there have been two recent household-based HIV prevalence surveys (the Dominican Republic, Mali, Niger, Tanzania, and Zambia)...
  12. pmc Errors in 'BED'-derived estimates of HIV incidence will vary by place, time and age
    Timothy B Hallett
    Imperial College London, London, United Kingdom
    PLoS ONE 4:e5720. 2009
    ....
  13. ncbi request reprint Appropriate evaluation of HIV prevention interventions: from experiment to full-scale implementation
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Sex Transm Infect 83:i55-60. 2007
    ..Remarkably little is known about how best to reduce HIV incidence because most trials focus on the reduction of risk behaviours and assume an effect on HIV incidence...
  14. ncbi request reprint Measuring effectiveness in community randomized trials of HIV prevention
    T B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, UK
    Int J Epidemiol 37:77-87. 2008
    ..Complicated HIV transmission dynamics make it unclear how to design and interpret results from community-randomized controlled trials (CRCT) of interventions to prevent infection...
  15. pmc Understanding the impact of male circumcision interventions on the spread of HIV in southern Africa
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS ONE 3:e2212. 2008
    ..We have used a mathematical model, parameterised using existing trial findings, to understand and predict the impact of circumcision programmes at the population level...
  16. ncbi request reprint Age at first sex and HIV infection in rural Zimbabwe
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London, UK
    Stud Fam Plann 38:1-10. 2007
    ..This finding can be explained by their having a greater lifetime number of sexual partners than those whose first sexual experience occurs later...
  17. ncbi request reprint Behaviour change in generalised HIV epidemics: impact of reducing cross-generational sex and delaying age at sexual debut
    T B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Sex Transm Infect 83:i50-54. 2007
    ..The importance of reducing cross-generational sex (young women having sex with older men) and delaying age at first sex on the spread of HIV at the population-level has been presumed but not scientifically investigated and quantified...
  18. pmc Declines in HIV prevalence can be associated with changing sexual behaviour in Uganda, urban Kenya, Zimbabwe, and urban Haiti
    T B Hallett
    Department of Infectious Disease Epidemiology, Imperial College, Norfolk Place, London W2 1PG, UK
    Sex Transm Infect 82:i1-8. 2006
    ..To determine whether observed changes in HIV prevalence in countries with generalised HIV epidemics are associated with changes in sexual risk behaviour...
  19. pmc Estimating incidence from prevalence in generalised HIV epidemics: methods and validation
    Timothy B Hallett
    Imperial College London, London, United Kingdom
    PLoS Med 5:e80. 2008
    ..Repeated cross-sectional measures of HIV prevalence are now becoming available for general populations in many countries, and we aim to develop and validate methods that use these data to estimate HIV incidence...
  20. pmc The impact of monitoring HIV patients prior to treatment in resource-poor settings: insights from mathematical modelling
    Timothy B Hallett
    Department of Infectious Disease Epidemiology, Imperial College London, United Kingdom
    PLoS Med 5:e53. 2008
    ..We investigated the potential influence of alternative patient management and ART initiation strategies on the impact of ART programmes in sub-Saharan Africa...
  21. ncbi request reprint HIV decline associated with behavior change in eastern Zimbabwe
    Simon Gregson
    Department of Infectious Disease Epidemiology, Imperial College London, UK
    Science 311:664-6. 2006
    ..Sexually experienced men and women reported reductions in casual sex of 49 and 22%, respectively, whereas recent cohorts reported delayed sexual debut. Selective AIDS-induced mortality contributed to the decline in HIV prevalence...
  22. pmc Patterns of self-reported behaviour change associated with receiving voluntary counselling and testing in a longitudinal study from Manicaland, Zimbabwe
    Ide Cremin
    Department of Infectious Disease Epidemiology, Imperial College London, St Marys Campus, Norfolk Place, Paddington, London, W2 1PG, UK
    AIDS Behav 14:708-15. 2010
    ..This study suggests that, among women, particularly those who are infected, behavioural risk reduction does occur following VCT...
  23. pmc Understanding the modes of transmission model of new HIV infection and its use in prevention planning
    Kelsey K Case
    Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, London, England
    Bull World Health Organ 90:831-838A. 2012
    ..We identified key questions to be asked when conducting an analysis and when interpreting the model results and make recommendations for strengthening the model's application in the future...
  24. pmc Assessing adult mortality in HIV-1-afflicted Zimbabwe (1998 -2003)
    Ben A Lopman
    Department of Infectious Disease Epidemiology, Imperial College London, England
    Bull World Health Organ 84:189-97. 2006
    ..To compare alternative methods to vital registration systems for estimating adult mortality, and describe patterns of mortality in Manicaland, Zimbabwe, which has been severely affected by HIV...
  25. doi request reprint Assessing evidence for behaviour change affecting the course of HIV epidemics: a new mathematical modelling approach and application to data from Zimbabwe
    Timothy B Hallett
    Imperial College London, London, UK
    Epidemics 1:108-17. 2009
    ..We aimed to develop a method to evaluate evidence for changes in risk behaviour altering the course of an HIV epidemic...
  26. pmc HIV decline in Zimbabwe due to reductions in risky sex? Evidence from a comprehensive epidemiological review
    Simon Gregson
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    Int J Epidemiol 39:1311-23. 2010
    ..We assessed the contributions of rising mortality, falling HIV incidence and sexual behaviour change to the decline in HIV prevalence...
  27. pmc Condom use by female sex workers and their clients in Mexico: who decides and does it matter?
    Annick Bórquez
    Department of Infectious Disease Epidemiology, Imperial College, London, UK
    Sex Transm Infect 87:254-6. 2011
    ..To explore the effect of different patterns of condom use by clients and female sex workers (FSW) on HIV transmission in Mexico...
  28. pmc HIV treatment as prevention: systematic comparison of mathematical models of the potential impact of antiretroviral therapy on HIV incidence in South Africa
    Jeffrey W Eaton
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Med 9:e1001245. 2012
    ..This study compares the predictions of several mathematical models simulating the same ART intervention programmes to determine the extent to which models agree about the epidemiological impact of expanded ART...
  29. pmc Changes in first-line cART regimens and short-term clinical outcome between 1996 and 2010 in The Netherlands
    Mikaela Smit
    Department of Infectious Disease Epidemiology, Imperial College, Faculty of Medicine, London, United Kingdom
    PLoS ONE 8:e76071. 2013
    ..Document progress in HIV-treatment in The Netherlands since 1996 by reviewing changing patterns of cART use and relating those to trends in patients' short-term clinical outcomes between 1996 and 2010...
  30. pmc Concurrent sexual partnerships and primary HIV infection: a critical interaction
    Jeffrey W Eaton
    Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London, W2 1PG, UK
    AIDS Behav 15:687-92. 2011
    ..The sensitivity of epidemic spread to the amount of concurrency is greater than predicted by models that do not include primary HIV infection...
  31. doi request reprint The new role of antiretrovirals in combination HIV prevention: a mathematical modelling analysis
    Ide Cremin
    Department of Infectious Disease Epidemiology, Imperial College London, UK
    AIDS 27:447-58. 2013
    ..We estimate the potential impact and cost-effectiveness of antiretroviral-based HIV prevention strategies...
  32. ncbi request reprint Mathematical models in the evaluation of health programmes
    Geoffrey P Garnett
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    Lancet 378:515-25. 2011
    ..The degree of rigor in model development and assessment can vary greatly, and there is a danger that existing beliefs inappropriately influence judgments about model assumptions and results...
  33. doi request reprint Modelling the global competing risks of a potential interaction between injectable hormonal contraception and HIV risk
    Ailsa R Butler
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    AIDS 27:105-13. 2013
    ..Some, but not all, observational studies have suggested an increase in the risk of HIV acquisition for women using injectable hormonal contraception (IHC)...
  34. pmc The potential impact of pre-exposure prophylaxis for HIV prevention among men who have sex with men and transwomen in Lima, Peru: a mathematical modelling study
    Gabriela B Gomez
    Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, United Kingdom
    PLoS Med 9:e1001323. 2012
    ..Consequently, there is a need to understand if and how PrEP can be used cost-effectively to prevent HIV infection in such populations...
  35. doi request reprint Interpreting declines in HIV prevalence: impact of spatial aggregation and migration on expected declines in prevalence
    P T Walker
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Sex Transm Infect 84:ii42-8. 2008
    ..Declines in the prevalence of HIV might occur due to natural epidemic dynamics rather than changes in risk behaviour. Determining the cause of an observed decline is important in understanding the epidemiology of HIV...
  36. pmc Role of widows in the heterosexual transmission of HIV in Manicaland, Zimbabwe, 1998-2003
    B A Lopman
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    Sex Transm Infect 85:i41-8. 2009
    ..AIDS is the main driver of young widowhood in southern Africa...
  37. ncbi request reprint Health benefits, costs, and cost-effectiveness of earlier eligibility for adult antiretroviral therapy and expanded treatment coverage: a combined analysis of 12 mathematical models
    Jeffrey W Eaton
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    Lancet Glob Health 2:e23-34. 2014
    ..We aimed to assess the potential health benefits, costs, and cost-effectiveness of various eligibility criteria for adult antiretroviral therapy and expanded treatment coverage...
  38. pmc Are Thai MSM willing to take PrEP for HIV prevention? An analysis of attitudes, preferences and acceptance
    Ana Wheelock
    Centre for Patient Safety and Service Quality, Imperial College London, London, United Kingdom
    PLoS ONE 8:e54288. 2013
    ..We aimed to understand the attitudes, preferences and acceptance of oral and parenteral PrEP among men who have sex with men (MSM) in Thailand...
  39. ncbi request reprint Maximising the effect of combination HIV prevention through prioritisation of the people and places in greatest need: a modelling study
    Sarah Jane Anderson
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK Electronic address
    Lancet 384:249-56. 2014
    ..We hypothesised that focusing appropriate interventions on geographies and key populations at high risk of HIV infection could improve the effect of investments in the HIV response...
  40. pmc HIV treatment as prevention: considerations in the design, conduct, and analysis of cluster randomized controlled trials of combination HIV prevention
    Marie Claude Boily
    Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, UK
    PLoS Med 9:e1001250. 2012
    ..The preplanned, interactive use of mathematical models during C-RCTs will also provide a valuable opportunity to validate and refine model projections...
  41. pmc Examining the promise of HIV elimination by 'test and treat' in hyperendemic settings
    Peter J Dodd
    Imperial College London, London, UK
    AIDS 24:729-35. 2010
    ....
  42. ncbi request reprint Preexposure prophylaxis will have a limited impact on HIV-1 drug resistance in sub-Saharan Africa: a comparison of mathematical models
    David A M C van de Vijver
    aDepartment of Virology, Erasmus Medical Centre, Erasmus University, Rotterdam, the Netherlands bDepartments of Infectious Diseases and Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA cDepartment of Infection and Population Health, University College London dDepartment of Infectious Disease Epidemiology, Imperial College London, London, UK eDivision of Infectious Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA fPharmAccess Foundation and Department of Global Health, Academic Medical Center of the University of Amsterdam, Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands
    AIDS 27:2943-51. 2013
    ..We compared standardized outcomes from three independent mathematical models simulating the impact of PrEP on HIV transmission and drug resistance in sub-Saharan African countries...
  43. doi request reprint Sex with stitches: assessing the resumption of sexual activity during the postcircumcision wound-healing period
    Paul C Hewett
    Population Council, Lusaka, Zambia
    AIDS 26:749-56. 2012
    ..This study uses observational data collected as part of Zambia's male circumcision program to measure sexual behavior in the postsurgical healing period and to model its influence on HIV transmission for men and their partners...
  44. pmc Late entry to HIV care limits the impact of anti-retroviral therapy in The Netherlands
    Colette Smit
    HIV Monitoring Foundation Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 3:e1949. 2008
    ..To explain differences in survival in the first three years of combination anti-retroviral therapy (cART) between HIV treatment centres in The Netherlands...