U Griesenbach

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. Griesenbach U, Vicente C, Roberts M, Meng C, Soussi S, Xenariou S, et al. Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer. Biomaterials. 2011;32:2614-24 pubmed publisher
    ..This has allowed us to validate that GL67A, which is currently in clinical use, can generate significant amounts of recombinant protein in fully differentiated human air liquid interface cultures and the ovine lung in vivo. ..
  2. Alton E, Boyd A, Davies J, Gill D, Griesenbach U, Harrison P, et al. Genetic medicines for CF: Hype versus reality. Pediatr Pulmonol. 2016;51:S5-S17 pubmed publisher
    ..We hope that this review will contribute to the ongoing discussion about the hype versus reality of genetic medicine-based treatment approaches in CF. Pediatr Pulmonol. 2016;51:S5-S17. © 2016 Wiley Periodicals, Inc. ..
  3. Griesenbach U, Smith S, Farley R, Singh C, Alton E. Validation of nasal potential difference measurements in gut-corrected CF knockout mice. Am J Respir Cell Mol Biol. 2008;39:490-6 pubmed publisher
    ..These data should allow a more informed use of CF animals in future studies. ..

Detail Information

Publications3

  1. Griesenbach U, Vicente C, Roberts M, Meng C, Soussi S, Xenariou S, et al. Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer. Biomaterials. 2011;32:2614-24 pubmed publisher
    ..This has allowed us to validate that GL67A, which is currently in clinical use, can generate significant amounts of recombinant protein in fully differentiated human air liquid interface cultures and the ovine lung in vivo. ..
  2. Alton E, Boyd A, Davies J, Gill D, Griesenbach U, Harrison P, et al. Genetic medicines for CF: Hype versus reality. Pediatr Pulmonol. 2016;51:S5-S17 pubmed publisher
    ..We hope that this review will contribute to the ongoing discussion about the hype versus reality of genetic medicine-based treatment approaches in CF. Pediatr Pulmonol. 2016;51:S5-S17. © 2016 Wiley Periodicals, Inc. ..
  3. Griesenbach U, Smith S, Farley R, Singh C, Alton E. Validation of nasal potential difference measurements in gut-corrected CF knockout mice. Am J Respir Cell Mol Biol. 2008;39:490-6 pubmed publisher
    ..These data should allow a more informed use of CF animals in future studies. ..