A Godkin

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi Naturally processed HLA class II peptides reveal highly conserved immunogenic flanking region sequence preferences that reflect antigen processing rather than peptide-MHC interactions
    A J Godkin
    Nuffield Department of Medicine, Molecular Immunology Group, Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    J Immunol 166:6720-7. 2001
  2. ncbi Characterization of novel HLA-DR11-restricted HCV epitopes reveals both qualitative and quantitative differences in HCV-specific CD4+ T cell responses in chronically infected and non-viremic patients
    A Godkin
    Imperial College of Science, Technology and Medicine, St Mary s Hospital, London, GB
    Eur J Immunol 31:1438-46. 2001
  3. ncbi Immune tolerance to hepatitis C virus acquired during engraftment of bone marrow transplant
    A Godkin
    Department of Medicine A, Imperial College of Science, Technology and Medicine, St Mary s Hospital, Paddington, London, UK
    J Viral Hepat 12:604-8. 2005
  4. ncbi Use of complete eluted peptide sequence data from HLA-DR and -DQ molecules to predict T cell epitopes, and the influence of the nonbinding terminal regions of ligands in epitope selection
    A J Godkin
    Molecular Immunology Group, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom
    J Immunol 161:850-8. 1998
  5. ncbi In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope
    R P Anderson
    Institute of Molecular Medicine, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK
    Nat Med 6:337-42. 2000

Detail Information

Publications5

  1. ncbi Naturally processed HLA class II peptides reveal highly conserved immunogenic flanking region sequence preferences that reflect antigen processing rather than peptide-MHC interactions
    A J Godkin
    Nuffield Department of Medicine, Molecular Immunology Group, Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    J Immunol 166:6720-7. 2001
    ..Recognition of these allele-transcending patterns in the PFRs may prove useful in epitope identification and vaccine design...
  2. ncbi Characterization of novel HLA-DR11-restricted HCV epitopes reveals both qualitative and quantitative differences in HCV-specific CD4+ T cell responses in chronically infected and non-viremic patients
    A Godkin
    Imperial College of Science, Technology and Medicine, St Mary s Hospital, London, GB
    Eur J Immunol 31:1438-46. 2001
    ..The frequency and phenotype of memory cells is likely to reflect the magnitude of the initial immune response, and suggests that a high frequency of IFN-gamma-secreting CD4+ T cells to multiple epitopes are important in clearance of HCV...
  3. ncbi Immune tolerance to hepatitis C virus acquired during engraftment of bone marrow transplant
    A Godkin
    Department of Medicine A, Imperial College of Science, Technology and Medicine, St Mary s Hospital, Paddington, London, UK
    J Viral Hepat 12:604-8. 2005
    ..From the above observations, it is plausible that the introduction of foreign viral antigen into the thymus may lead to subsequent acquired central tolerance...
  4. ncbi Use of complete eluted peptide sequence data from HLA-DR and -DQ molecules to predict T cell epitopes, and the influence of the nonbinding terminal regions of ligands in epitope selection
    A J Godkin
    Molecular Immunology Group, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom
    J Immunol 161:850-8. 1998
    ..Thus, the use of complete eluted peptide sequence data offers a powerful approach to the prediction of HLA-DQ and -DR peptide ligands and T cell epitopes...
  5. ncbi In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope
    R P Anderson
    Institute of Molecular Medicine, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK
    Nat Med 6:337-42. 2000
    ..Discovery of this dominant epitope may allow development of antigen-specific immunotherapy for CD...