Research Topics
| Helena M GardinerSummaryAffiliation: Imperial College Country: UK Publications
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Detail Information
Publications
Myocardial tissue Doppler and long axis function in the fetal heartHelena M Gardiner
Royal Brompton Hospital, UK
Int J Cardiol 113:39-47. 2006..Current echocardiographic assessment of fetal ventricular function uses relatively crude measures and this has led to inconsistencies in assessment of diastolic function. Long axis parameters may be more insightful...
Fetal cardiac interventionsHelena M Gardiner
Royal Brompton Hospital, Imperial College, London, UK
Clin Obstet Gynecol 48:956-63. 2005
Increased periconceptual maternal glycated haemoglobin in diabetic mothers reduces fetal long axis cardiac functionH M Gardiner
Royal Brompton Hospital, London, UK
Heart 92:1125-30. 2006..To compare ventricular long axis function in fetuses of diabetic mothers (FDM) with contemporaneously studied normal controls (N) and to assess the effect of pre-pregnancy diabetic control on these measurements...
Progression of fetal heart disease and rationale for fetal intracardiac interventionsHelena M Gardiner
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Queen Charlotte s and Chelsea Hospital, Du Cane Road, London W12 ONN, UK
Semin Fetal Neonatal Med 10:578-85. 2005..These signs suggest better fetal cardiopulmonary development and improved surgical outcomes...
Images in cardiovascular medicine. Pericardiocentesis at 14 weeks: effective treatment of pericardial effusion complicating right ventricular diverticulumHelena M Gardiner
Faculty of Medicine, Imperial College London, Queen Charlotte's and Chelsea and Hammersmith Hospitals, London, UK
Circulation 112:e120. 2005
Response of the fetal heart to changes in load: from hyperplasia to heart failureH M Gardiner
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Queen Charlotte's and Chelsea Hospital, Du Cane Road, London, W12 ONN, UK
Heart 91:871-3. 2005
Fetal ECG: a novel predictor of atrioventricular block in anti-Ro positive pregnanciesHelena M Gardiner
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Queen Charlotte s and Chelsea Hospital, Du Cane Road, London, W12 0HS, UK
Heart 93:1454-60. 2007..First-degree atrioventricular heart block (1 degrees AVB) is reported in a third of Ro/La fetuses but as most have a normal postnatal ECG this may reflect inadequacies of Doppler measurement techniques...
Mind the gap! What we don't know about right aortic arches and aberrant branchesH M Gardiner
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Queen Charlotte's and Chelsea Hospital, Du Cane Road, London W12 ONN
Ultrasound Obstet Gynecol 28:868-9. 2006
In-utero intervention for severe congenital heart diseaseHelena M Gardiner
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Queen Charlotte s and Chelsea Hospital, Du Cane Road, London, W12 ONN, UK
Best Pract Res Clin Obstet Gynaecol 22:49-61. 2008..Progress in these endeavours has been variable but - overall - shows promise for treatment of the human fetus...
Early environmental influences on vascular developmentHelena M Gardiner
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Queen Charlotte s and Chelsea Hospital, London, UK
Early Hum Dev 83:819-23. 2007..However, individuals studied during fetal life are now reaching adulthood and will provide us with new insights into vascular programming...
Morphologic and functional predictors of eventual circulation in the fetus with pulmonary atresia or critical pulmonary stenosis with intact septumHelena M Gardiner
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College at Queen Charlotte s and Chelsea Hospital, London, United Kingdom
J Am Coll Cardiol 51:1299-308. 2008....
The case for fetal cardiac interventionH M Gardiner
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Queen Charlotte s and Chelsea Hospital, Du Cane Road, London W120HS, UK
Heart 95:1648-52. 2009....
Keeping abreast of advances in fetal cardiologyHelena M Gardiner
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Queen Charlotte s and Chelsea Hospital, London, UK
Early Hum Dev 82:415-9. 2006..These technologies may permit successful fetal surgical procedures. Cross discipline collaboration has been key in enabling these advances which have changed the face of fetal cardiology...
Non-invasive intrapartum fetal ECG: preliminary reportMyles J O Taylor
Queen Charlotte's and Chelsea Hospital and Division of Paediatrics, Obstetrics and Gynaecology, Faculty of Medicine, Imperial College, London, UK
BJOG 112:1016-21. 2005....
Myocardial strain abnormalities in fetal congenital heart disease assessed by speckle tracking echocardiographyIoannis Germanakis
Reproductive Biology, Division of Cancer, Faculty of Medicine, Imperial College London, London, UK
Fetal Diagn Ther 32:123-30. 2012..To compare myocardial deformation patterns in fetuses with congenital heart disease (CHD) with our reference range using speckle tracking echocardiography...
PR interval: a comparison of electrical and mechanical methods in the fetusLucia Pasquini
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College at Queen Charlotte s and Chelsea Hospital, London, UK
Early Hum Dev 83:231-7. 2007..Mechanical surrogates are used to assess fetal cardiac electrical activity...
Prenatal diagnosis of absent right and persistent left superior vena cavaLucia Pasquini
Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, London, W12 ONN, UK
Prenat Diagn 26:700-2. 2006..CONCLUSION: Persistence of LSVC is a known variant of the systemic venous return. In the setting of an otherwise structurally normal heart, absence of the right but persistence of LSVC is rare...
Morphological and physiological predictors of fetal aortic coarctationHikoro Matsui
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Queen Charlotte s and Chelsea Hospital, Du Cane Rd, London, W12 0HS, UK
Circulation 118:1793-801. 2008..Prenatal diagnosis of aortic coarctation suffers from high false-negative rates at screening and poor specificity...
Reversal of twin-twin transfusion syndrome: frequency, vascular anatomy, associated anomalies and outcomeLing Y Wee
Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, UK
Prenat Diagn 24:104-10. 2004..To determine the frequency of reversal of transfusional gradient and phenotype in a large cohort of prospectively studied cases of twin-twin transfusion syndrome (TTTS) and seek evidence of clinical or placental anastomotic associations...
Non-invasive fetal electrocardiography in singleton and multiple pregnanciesMyles J O Taylor
Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, and Institute of Reproductive and Developmental Biology, Imperial College, London, UK
BJOG 110:668-78. 2003..The fECG time intervals described will enable the identification of pathological fECG recordings from high risk pregnancies where fECG abnormalities are suspected...
Z-scores of the fetal aortic isthmus and duct: an aid to assessing arch hypoplasiaL Pasquini
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Queen Charlotte s and Chelsea Hospital, London, UK
Ultrasound Obstet Gynecol 29:628-33. 2007..The aim of our study was to develop Z-scores for the aortic isthmus in normal fetuses as a reference for fetuses with suspected coarctation...
Congenital heart disease and aneuploidyR C Wimalasundera
Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, London, UK
Prenat Diagn 24:1116-22. 2004..In this chapter, we review the frequency and types of aneuploidy associated with the commonly diagnosed CHD and discuss their management...
Isolated non-compaction of the ventricular myocardium: prenatal diagnosis and natural historyA A Karatza
Department of Paediatric Cardiology, Royal Brompton and Harefield NHS Trust and National Heart and Lung Institute, London, UK
Ultrasound Obstet Gynecol 21:75-80. 2003..The uncertainty of prognosis and the familial recurrence described elsewhere indicate the difficulty of counseling and the value of prenatal diagnosis, which is feasible using currently available ultrasonographic equipment...
Influence of twin-twin transfusion syndrome on fetal cardiovascular structure and function: prospective case-control study of 136 monochorionic twin pregnanciesA A Karatza
Department of Maternal-Fetal Medicine, Queen Charlotte's and Chelsea Hospital, Imperial College, London, UK
Heart 88:271-7. 2002..The high prevalence of congenital heart disease in monochorionic diamniotic twins merits detailed fetal echocardiography...
Twin-twin transfusion syndrome: the influence of intrauterine laser photocoagulation on arterial distensibility in childhoodHelena M Gardiner
Department of Pediatric Cardiology, Royal Brompton Hospital, London, UK
Circulation 107:1906-11. 2003..We tested this by examining pulse wave velocity (PWV) in brachial arteries of twin survivors of TTTS treated with and without laser therapy...
Fetal pulmonary valvuloplasty for critical pulmonary stenosis or atresia with intact septumGerald Tulzer
Children's Heart Centre Linz, Children's Hospital of Linz, Austria
Lancet 360:1567-8. 2002..Surgery on selected fetuses with semilunar valve stenosis or atresia, or both, can extend pregnancy and favourably change the postnatal surgical options...
Telemedicine in pediatric and perinatal cardiology: economic evaluation of a service in English hospitalsRobin Dowie
Health Economics Research Group, Brunel University, Uxbridge, Middlesex, UK
Int J Technol Assess Health Care 23:116-25. 2007..The aims of this study were to observe how district hospitals use a pediatric telecardiology service, and to compare the costs and outcomes of patients referred to specialists by means of this service or conventionally...
