Russell G Foster

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. pmc In silico characterisation and chromosomal localisation of human RRH (peropsin)--implications for opsin evolution
    James Bellingham
    Gene Targeting Unit, Department of Neuromuscular Diseases, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, St Dunstan s Road, London, W6 8RP, UK
    BMC Genomics 4:3. 2003
  2. ncbi request reprint The rhythm of rest and excess
    Russell G Foster
    Department of Visual Neuroscience, Imperial College London, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK
    Nat Rev Neurosci 6:407-14. 2005
  3. ncbi request reprint Teleost multiple tissue (tmt) opsin: a candidate photopigment regulating the peripheral clocks of zebrafish?
    Paraskevi Moutsaki
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Hospital, Fulham Palace Road, W6 8RF, London, UK
    Brain Res Mol Brain Res 112:135-45. 2003
  4. ncbi request reprint Zebrafish melanopsin: isolation, tissue localisation and phylogenetic position
    James Bellingham
    Department of Integrative and Molecular Neuroscience, Imperial College Faculty of Medicine, Charing Cross Hospital, London, UK
    Brain Res Mol Brain Res 107:128-36. 2002
  5. ncbi request reprint Residual photosensitivity in mice lacking both rod opsin and cone photoreceptor cyclic nucleotide gated channel 3 alpha subunit
    Alun R Barnard
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, London, UK
    Vis Neurosci 21:675-83. 2004
  6. ncbi request reprint Neuropsin (Opn5): a novel opsin identified in mammalian neural tissue
    Emma E Tarttelin
    Department of Integrative and Molecular Neuroscience, Imperial College London, Charing Cross Hospital, St Dunstan s Road, London W6 8RP, UK
    FEBS Lett 554:410-6. 2003
  7. ncbi request reprint Structure and evolution of the teleost extraretinal rod-like opsin (errlo) and ocular rod opsin (rho) genes: is teleost rho a retrogene?
    James Bellingham
    Gene Targeting Unit, Department of Neuromuscular Diseases, Division of Neuroscience, Imperial College London, Charing Cross Hospital, St Dunstan s Road, London, W6 8RP, United Kingdom
    J Exp Zool B Mol Dev Evol 297:1-10. 2003
  8. ncbi request reprint Expression of the candidate circadian photopigment melanopsin (Opn4) in the mouse retinal pigment epithelium
    Stuart N Peirson
    Department of Visual Neuroscience, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK
    Brain Res Mol Brain Res 123:132-5. 2004
  9. ncbi request reprint Melanopsin: another way of signaling light
    Stuart Peirson
    Division of Neuroscience and Mental Health, Department of Cellular and Molecular Neuroscience, Faculty of Medicine, Charing Cross Hospital, Imperial College London, London W6 8RF, United Kingdom
    Neuron 49:331-9. 2006
  10. ncbi request reprint Expression of opsin genes early in ocular development of humans and mice
    Emma E Tarttelin
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, St Dunstan s Road, London W6 8RP, UK
    Exp Eye Res 76:393-6. 2003

Collaborators

Detail Information

Publications38

  1. pmc In silico characterisation and chromosomal localisation of human RRH (peropsin)--implications for opsin evolution
    James Bellingham
    Gene Targeting Unit, Department of Neuromuscular Diseases, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, St Dunstan s Road, London, W6 8RP, UK
    BMC Genomics 4:3. 2003
    ..Exceptions to this are RGR-opsin and melanopsin, whose genes have very different intron insertion positions. The gene structure of another opsin, peropsin (retinal pigment epithelium-derived rhodopsin homologue, RRH) is unknown...
  2. ncbi request reprint The rhythm of rest and excess
    Russell G Foster
    Department of Visual Neuroscience, Imperial College London, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK
    Nat Rev Neurosci 6:407-14. 2005
    ..Our occupation of the night is having unanticipated costs for both our physical and mental health, which, if continued, might condemn whole sectors of our society to a dismal future...
  3. ncbi request reprint Teleost multiple tissue (tmt) opsin: a candidate photopigment regulating the peripheral clocks of zebrafish?
    Paraskevi Moutsaki
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Hospital, Fulham Palace Road, W6 8RF, London, UK
    Brain Res Mol Brain Res 112:135-45. 2003
    ..Collectively the data suggest that tmt-opsin is a strong candidate for the photic regulation of zebrafish peripheral clocks...
  4. ncbi request reprint Zebrafish melanopsin: isolation, tissue localisation and phylogenetic position
    James Bellingham
    Department of Integrative and Molecular Neuroscience, Imperial College Faculty of Medicine, Charing Cross Hospital, London, UK
    Brain Res Mol Brain Res 107:128-36. 2002
    ..They might represent a separate branch of photopigment evolution in the vertebrates or they may have a non-direct photosensory function, perhaps as a photoisomerase, in non-rod, non-cone light detection...
  5. ncbi request reprint Residual photosensitivity in mice lacking both rod opsin and cone photoreceptor cyclic nucleotide gated channel 3 alpha subunit
    Alun R Barnard
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, London, UK
    Vis Neurosci 21:675-83. 2004
    ..Thus, it seems that non-rod non-cone photoreceptors can drive many, but not all, non-image-forming light responses...
  6. ncbi request reprint Neuropsin (Opn5): a novel opsin identified in mammalian neural tissue
    Emma E Tarttelin
    Department of Integrative and Molecular Neuroscience, Imperial College London, Charing Cross Hospital, St Dunstan s Road, London W6 8RP, UK
    FEBS Lett 554:410-6. 2003
    ..Neuropsin shares 25-30% amino acid identity with all known opsins, making it the founding member of a new opsin family. It is expressed in the eye, brain, testis and spinal cord...
  7. ncbi request reprint Structure and evolution of the teleost extraretinal rod-like opsin (errlo) and ocular rod opsin (rho) genes: is teleost rho a retrogene?
    James Bellingham
    Gene Targeting Unit, Department of Neuromuscular Diseases, Division of Neuroscience, Imperial College London, Charing Cross Hospital, St Dunstan s Road, London, W6 8RP, United Kingdom
    J Exp Zool B Mol Dev Evol 297:1-10. 2003
    ....
  8. ncbi request reprint Expression of the candidate circadian photopigment melanopsin (Opn4) in the mouse retinal pigment epithelium
    Stuart N Peirson
    Department of Visual Neuroscience, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK
    Brain Res Mol Brain Res 123:132-5. 2004
    ..Our results raise questions about the presumed function of melanopsin, and highlight the need for biochemical studies on this protein...
  9. ncbi request reprint Melanopsin: another way of signaling light
    Stuart Peirson
    Division of Neuroscience and Mental Health, Department of Cellular and Molecular Neuroscience, Faculty of Medicine, Charing Cross Hospital, Imperial College London, London W6 8RF, United Kingdom
    Neuron 49:331-9. 2006
    ..This review discusses the signaling pathways that may underlie melanopsin-dependent phototransduction in native pRGCs, as well as the many exciting challenges ahead...
  10. ncbi request reprint Expression of opsin genes early in ocular development of humans and mice
    Emma E Tarttelin
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, St Dunstan s Road, London W6 8RP, UK
    Exp Eye Res 76:393-6. 2003
    ..Human non-rod, non-cone opsins are also all expressed early, by 8.6 weeks post-conception. The implications of these observations are discussed with regard to the possible functions of these opsins at early stages of ocular development...
  11. ncbi request reprint Melanopsin retinal ganglion cells and the maintenance of circadian and pupillary responses to light in aged rodless/coneless (rd/rd cl) mice
    Ma ayan Semo
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK
    Eur J Neurosci 17:1793-801. 2003
    ..These findings, together with recent studies on melanopsin knockout mice, are consistent with the hypothesis that melanopsin-expressing ganglion cells are photosensitive and mediate a range of irradiance-detection tasks...
  12. ncbi request reprint Opsins and mammalian photoentrainment
    James Bellingham
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Hospital, Fulham Palace Road, London, W6 8RF, UK
    Cell Tissue Res 309:57-71. 2002
    ....
  13. ncbi request reprint Light-evoked FOS induction within the suprachiasmatic nuclei (SCN) of melanopsin knockout (Opn4-/-) mice: a developmental study
    Daniela Lupi
    Department of Visual Neuroscience, Division of Neuroscience and Mental Health, Imperial College London, Charing Cross Hospital Campus, London, UK
    Chronobiol Int 23:167-79. 2006
    ..These results are related to the broader context of recent findings and the potential role(s) of a neonatal photoreceptor...
  14. pmc Short-wavelength light sensitivity of circadian, pupillary, and visual awareness in humans lacking an outer retina
    Farhan H Zaidi
    Division of Neuroscience and Mental Health, Faculty of Medicine, Imperial College London, London W6 8RF, United Kingdom
    Curr Biol 17:2122-8. 2007
    ....
  15. ncbi request reprint The suitability of actigraphy, diary data, and urinary melatonin profiles for quantitative assessment of sleep disturbances in schizophrenia: a case report
    Katharina Wulff
    Department of Visual Neuroscience, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, London, UK
    Chronobiol Int 23:485-95. 2006
    ..These circadian abnormalities may reinforce the altered sleep patterns and the problems of cognitive function and social engagement associated with schizophrenic...
  16. ncbi request reprint Melanopsin (Opn4) positive cells in the cat retina are randomly distributed across the ganglion cell layer
    Ma ayan Semo
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, London, UK
    Vis Neurosci 22:111-6. 2005
    ..Melanopsin containing cells showed no clear center-to-periphery gradient in their distribution and were comprised of a relatively uniform cellular population...
  17. ncbi request reprint Long-term constant light induces constitutive elevated expression of mPER2 protein in the murine SCN: a molecular basis for Aschoff's rule?
    Marta Muñoz
    Department of Visual Neuroscience, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College, Charing Cross Hospital, London, UK
    J Biol Rhythms 20:3-14. 2005
    ....
  18. ncbi request reprint Seeing the light...in a new way
    Russell G Foster
    Department of Visual Neuroscience, Imperial College Faculty of Medicine, London, UK
    J Neuroendocrinol 16:179-80. 2004
    ..These receptors may even help modulate our mood and sense of well-being...
  19. ncbi request reprint Light-induced c-fos in melanopsin retinal ganglion cells of young and aged rodless/coneless (rd/rd cl) mice
    Ma ayan Semo
    Department of Integrative and Molecular Neuroscience, Imperial College London, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK
    Eur J Neurosci 18:3007-17. 2003
    ..Collectively, our data suggest that melanopsin RGCs form a heterogeneous population of neurons, and that most of the light-induced c-fos expression within these cells is associated with the endogenous photosensitivity of these neurons...
  20. ncbi request reprint Calcium imaging reveals a network of intrinsically light-sensitive inner-retinal neurons
    Sumathi Sekaran
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Imperial College London, Charing Cross Hospital, London, United Kingdom
    Curr Biol 13:1290-8. 2003
    ..These data are consistent with the presence of a novel inner-retinal photoreceptor mediating non-image-forming irradiance detection...
  21. ncbi request reprint Keeping an eye on the time: the Cogan Lecture
    Russell G Foster
    Department of Integrative and Molecular Neuroscience, Faculty of Medicine, Imperial College of Science, Engineering, and Medicine, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, United Kingdom
    Invest Ophthalmol Vis Sci 43:1286-98. 2002
  22. ncbi request reprint Non-rod, non-cone photoreception in the vertebrates
    Russell G Foster
    Department of Integrative and Molecular Neuroscience, Faculty of Medicine, Imperial College of Science, Engineering and Medicine, Charing Cross Hospital, Fulham Palace Road, W6 8RF, London, UK
    Prog Retin Eye Res 21:507-27. 2002
    ..We also hope to convince the more casual reader that there is much more to vertebrate photoreceptors than the study of retinal rods and cones...
  23. ncbi request reprint Non-rod, non-cone photoreception in rodents and teleost fish
    Russell G Foster
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK
    Novartis Found Symp 253:3-23; discussion 23-30, 52-5, 102-9. 2003
    ..We compare non-rod, non-cone ocular photoreceptors in mammals and fish, and examine the criteria used to place candidate photopigment molecules into a functional context...
  24. ncbi request reprint Inner retinal photoreceptors (IRPs) in mammals and teleost fish
    Russell G Foster
    Department of Visual Neuroscience, Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College of Science, Engineering and Medicine, Charing Cross Hospital, Fulham Palace Road, London, UK W6 8RF
    Photochem Photobiol Sci 3:617-27. 2004
    ..The discovery of IRPs in the vertebrates tells us that despite 150 years of research, we still have much to learn about how the eye processes light...
  25. pmc Classical and melanopsin photoreception in irradiance detection: negative masking of locomotor activity by light
    Stewart Thompson
    Howard Hughes Medical Institute, Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, Iowa 52242, USA
    Eur J Neurosci 27:1973-9. 2008
    ..Together the evidence demonstrates a pronounced and sustained classical photoreceptor input to irradiance detection for negative masking, and suggests one role of classical photoreceptor input is to constrain dynamic range...
  26. ncbi request reprint Microarray analysis and functional genomics identify novel components of melanopsin signaling
    Stuart N Peirson
    Circadian and Visual Neuroscience Group, University of Oxford, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, United Kingdom
    Curr Biol 17:1363-72. 2007
    ..Here, we use a microarray-based approach, which we term transcriptional recalibration, coupled with functional genomics to identify downstream targets of melanopsin signaling...
  27. pmc Isolation and characterization of melanopsin (Opn4) from the Australian marsupial Sminthopsis crassicaudata (fat-tailed dunnart)
    Susana S Pires
    Circadian and Visual Neuroscience, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK
    Proc Biol Sci 274:2791-9. 2007
    ..This approach reveals that the two marsupials show a higher sequence identity than that seen between rodents and primates, despite separating at approximately the same point in time, some 65-85 Myr ago...
  28. ncbi request reprint Melanopsin: an exciting photopigment
    Mark W Hankins
    Circadian and Visual Neuroscience Group, Nuffield Laboratory of Ophthalmology, University of Oxford, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK
    Trends Neurosci 31:27-36. 2008
    ..Here we outline the discovery of this remarkable new photoreceptor system, review the structure of melanopsin and conclude with a working model of melanopsin phototransduction...
  29. ncbi request reprint Neurobiology: bright blue times
    Russell G Foster
    Imperial Coll, London, UK
    Nature 433:698-9. 2005
  30. ncbi request reprint Absence of phosphoglucose isomerase-1 in retinal photoreceptor, pigment epithelium and Muller cells
    Simon N Archer
    School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK
    Eur J Neurosci 19:2923-30. 2004
    ..We hypothesize that the unique metabolic needs of photoreceptors justify this trade-off...
  31. pmc The effects of rod and cone loss on the photic regulation of locomotor activity and heart rate
    Stewart Thompson
    Nuffield Laboratory of Ophthalmology, The John Radcliffe Hospital, Headley Way, University of Oxford, Roosevelt Drive, Oxford OX3 9DU, UK
    Eur J Neurosci 28:724-9. 2008
    ..Surprisingly, this irradiance detection response is dependent upon rod and cone photoreceptors, with no apparent contribution from melanopsin pRGCs...
  32. ncbi request reprint Placing ocular mutants into a functional context: a chronobiological approach
    Urs Albrecht
    Division of Biochemistry, Department of Medicine, University of Fribourg, Rue du Musee 5, Switzerland
    Methods 28:465-77. 2002
    ..Such measurements have, and continue to provide, a remarkably powerful assay of how light is detected and transduced to regulate circadian rhythms. The methods used for such measurements in mice are described in the following article...
  33. ncbi request reprint VA opsin, melanopsin, and an inherent light response within retinal interneurons
    Aaron Jenkins
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Hospital, London, United Kingdom
    Curr Biol 13:1269-78. 2003
    ..As yet, there has been little more than speculation as to the physiological function of these opsins within local retinal circuit neurons...
  34. ncbi request reprint A green cone-like pigment in the 'blind' mole-rat Spalax ehrenbergi: functional expression and photochemical characterization
    Jannie W H Janssen
    Department of Biochemistry UMC 160, Nijmegen Center for Molecular Lift, Sciences, University of Nijmegen Medical School, PO Box 9101, Nijmegen, The Netherlands
    Photochem Photobiol Sci 2:1287-91. 2003
    ..Finally, the slow part of the photocascade deviates in some aspects from that of sighted mammals. The possible relevance of these findings for the evolutionary adaptation of Spalax to a subterranean ecotope is discussed...
  35. ncbi request reprint Circadian vision
    Russell G Foster
    Department of Ophthalmology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Curr Biol 17:R746-51. 2007
  36. ncbi request reprint 2-Aminoethoxydiphenylborane is an acute inhibitor of directly photosensitive retinal ganglion cell activity in vitro and in vivo
    Sumathi Sekaran
    Circadian and Visual Neuroscience Group, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford OX3 7BN, United Kingdom
    J Neurosci 27:3981-6. 2007
    ..Collectively, our data further elucidate the phototransduction pathway in the photosensitive RGCs and demonstrate that 2-APB can be used to silence activity in these cells both in vitro and in vivo...
  37. ncbi request reprint Light, photoreceptors, and circadian clocks
    Russell G Foster
    Division of Circadian and Visual Neuroscience, University of Oxford, UK
    Methods Mol Biol 362:3-28. 2007
    ..The aims of this chapter are to provide an accessible introduction to photobiological methods and explain why these approaches need to be applied to the study of circadian systems...
  38. ncbi request reprint Visual pigments and oil droplets in diurnal lizards: a comparative study of Caribbean anoles
    Ellis R Loew
    Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA
    J Exp Biol 205:927-38. 2002
    ..These findings suggest that anoline visual pigments, as far as they determine visual system spectral sensitivity, are not necessarily adapted to the photic environment or to the color of significant visual targets (e.g. dewlaps)...