N M Fisk

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi request reprint Effect of direct fetal opioid analgesia on fetal hormonal and hemodynamic stress response to intrauterine needling
    N M Fisk
    Department of Maternal and Fetal Medicine, Imperial College School of Medicine, Queen Charlotte s and Chelsea Hospital, London, United Kingdom
    Anesthesiology 95:828-35. 2001
  2. ncbi request reprint Fetal hypothalamic-pituitary-adrenal stress responses to invasive procedures are independent of maternal responses
    R Gitau
    Department of Maternal Medicine, Division of Paediatrics, Institute of Reproductive and Developmental Biology, Imperial College School of Medicine, Hammersmith Campus, London W12 0NN, United Kingdom
    J Clin Endocrinol Metab 86:104-9. 2001
  3. doi request reprint Transfusional fetal complications after single intrauterine death in monochorionic multiple pregnancy are reduced but not prevented by vascular occlusion
    K O'Donoghue
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, London, UK
    BJOG 116:804-12. 2009
  4. ncbi request reprint Doppler detection of arterio-arterial anastomoses in monochorionic twins: feasibility and clinical application
    M J Taylor
    Centre for Fetal Care, Department of Materno Fetal Medicine, Imperial College School of Medicine, Queen Charlotte s and Chelsea Hospital, Goldhawk Road, London W6 0XG, UK
    Hum Reprod 15:1632-6. 2000
  5. ncbi request reprint Umbilical cortisol levels as an indicator of the fetal stress response to assisted vaginal delivery
    R Gitau
    Department of Maternal and Fetal Medicine, Fetal and Neonatal Stress Research Centre, Imperial College School of Medicine, London, UK
    Eur J Obstet Gynecol Reprod Biol 98:14-7. 2001
  6. ncbi request reprint Pain and stress in the human fetus
    R P Smith
    Department of Maternal and Fetal Medicine, Centre for Fetal Care, Institute of Obstetrics and Gynaecology, Imperial College School of Medicine, Queen Charlotte s and Chelsea Hospital, Goldhawk Rd, W6 0XG, London, UK
    Eur J Obstet Gynecol Reprod Biol 92:161-5. 2000
  7. pmc Effect of antenatal administration of thyrotrophin releasing hormone on fetal flow velocity waveforms
    R Bajoria
    Institute of Obstetrics and Gynaecology, Royal Postgraduate Medical School, Queen Charlotte s and Chelsea Hospital, London
    Arch Dis Child Fetal Neonatal Ed 77:F127-30. 1997
  8. ncbi request reprint Transfer and metabolism of thyrotropin releasing hormone across the perfused human term placenta
    R Bajoria
    Institute of Obstetrics and Gynaecology, Royal Postgraduate Medical School, Queen Charlotte s and Chelsea Hospital, London, United Kingdom
    J Clin Endocrinol Metab 81:3476-82. 1996
  9. ncbi request reprint Freehand three-dimensional Doppler demonstration of monochorionic vascular anastomoses in vivo: a preliminary report
    A W Welsh
    Department of Maternal and Fetal Medicine, Queen Charlotte s and Chelsea Hospital, Institute of Reproductive and Developmental Biology, Imperial College School of Medicine, London UK
    Ultrasound Obstet Gynecol 18:317-24. 2001
  10. ncbi request reprint Development of three-dimensional power Doppler ultrasound imaging of fetoplacental vasculature
    A W Welsh
    Department of Maternal and Fetal Medicine, Queen Charlotte s and Chelsea Hospital, Institute of Reproductive and Developmental Biology, London, UK
    Ultrasound Med Biol 27:1161-70. 2001

Detail Information

Publications46

  1. ncbi request reprint Effect of direct fetal opioid analgesia on fetal hormonal and hemodynamic stress response to intrauterine needling
    N M Fisk
    Department of Maternal and Fetal Medicine, Imperial College School of Medicine, Queen Charlotte s and Chelsea Hospital, London, United Kingdom
    Anesthesiology 95:828-35. 2001
    ....
  2. ncbi request reprint Fetal hypothalamic-pituitary-adrenal stress responses to invasive procedures are independent of maternal responses
    R Gitau
    Department of Maternal Medicine, Division of Paediatrics, Institute of Reproductive and Developmental Biology, Imperial College School of Medicine, Hammersmith Campus, London W12 0NN, United Kingdom
    J Clin Endocrinol Metab 86:104-9. 2001
    ..4 + 5.08x, r = 0.51; n = 16; P = 0.04; CI for slope, 0.16-10.0), consistent with the maturation of the fetal pituitary before the fetal adrenal...
  3. doi request reprint Transfusional fetal complications after single intrauterine death in monochorionic multiple pregnancy are reduced but not prevented by vascular occlusion
    K O'Donoghue
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, London, UK
    BJOG 116:804-12. 2009
    ..To document co-twin death/pregnancy loss and brain injury after single intrauterine death (sIUD) in monochorionic pregnancies...
  4. ncbi request reprint Doppler detection of arterio-arterial anastomoses in monochorionic twins: feasibility and clinical application
    M J Taylor
    Centre for Fetal Care, Department of Materno Fetal Medicine, Imperial College School of Medicine, Queen Charlotte s and Chelsea Hospital, Goldhawk Road, London W6 0XG, UK
    Hum Reprod 15:1632-6. 2000
    ..6). We conclude that AAA can be detected in vivo with high sensitivity and specificity without undue prolongation of scanning times and have a role in risk stratification in the antenatal assessment of MC twins...
  5. ncbi request reprint Umbilical cortisol levels as an indicator of the fetal stress response to assisted vaginal delivery
    R Gitau
    Department of Maternal and Fetal Medicine, Fetal and Neonatal Stress Research Centre, Imperial College School of Medicine, London, UK
    Eur J Obstet Gynecol Reprod Biol 98:14-7. 2001
    ..While it is well established that delivery by elective caesarean section is less stressful for the fetus than normal vaginal delivery, little attention has been paid to the effect on the baby of an assisted delivery...
  6. ncbi request reprint Pain and stress in the human fetus
    R P Smith
    Department of Maternal and Fetal Medicine, Centre for Fetal Care, Institute of Obstetrics and Gynaecology, Imperial College School of Medicine, Queen Charlotte s and Chelsea Hospital, Goldhawk Rd, W6 0XG, London, UK
    Eur J Obstet Gynecol Reprod Biol 92:161-5. 2000
    ..During open fetal surgery, maternal general anaesthesia provides fetal anaesthesia. However, in closed procedures, fetal analgesia presents difficulties. The optimal drug, dose, and route of administration remain to be determined...
  7. pmc Effect of antenatal administration of thyrotrophin releasing hormone on fetal flow velocity waveforms
    R Bajoria
    Institute of Obstetrics and Gynaecology, Royal Postgraduate Medical School, Queen Charlotte s and Chelsea Hospital, London
    Arch Dis Child Fetal Neonatal Ed 77:F127-30. 1997
    ....
  8. ncbi request reprint Transfer and metabolism of thyrotropin releasing hormone across the perfused human term placenta
    R Bajoria
    Institute of Obstetrics and Gynaecology, Royal Postgraduate Medical School, Queen Charlotte s and Chelsea Hospital, London, United Kingdom
    J Clin Endocrinol Metab 81:3476-82. 1996
    ..These results suggest that human placenta acts as an enzymatic barrier to the free passage of TRH...
  9. ncbi request reprint Freehand three-dimensional Doppler demonstration of monochorionic vascular anastomoses in vivo: a preliminary report
    A W Welsh
    Department of Maternal and Fetal Medicine, Queen Charlotte s and Chelsea Hospital, Institute of Reproductive and Developmental Biology, Imperial College School of Medicine, London UK
    Ultrasound Obstet Gynecol 18:317-24. 2001
    ..To demonstrate the three-dimensional vascular anatomy of monochorionic placental anastomoses in vivo, both arterioarterial and arteriovenous...
  10. ncbi request reprint Development of three-dimensional power Doppler ultrasound imaging of fetoplacental vasculature
    A W Welsh
    Department of Maternal and Fetal Medicine, Queen Charlotte s and Chelsea Hospital, Institute of Reproductive and Developmental Biology, London, UK
    Ultrasound Med Biol 27:1161-70. 2001
    ..Fully freehand 3-D US does have a role in off-line reconstruction of vascular anatomy, although variability in the z plane precludes its use for volumetric measurement. (E-mail: a.welsh@ic.ac.uk)..
  11. ncbi request reprint Quantitative digital analysis of regional placental perfusion using power Doppler in placental abruption
    A W Welsh
    Centre for Fetal Care, Institute of Osbtetrics and Gynecology, Department of Maternal and Fetal Medicine, Imperial College School of Medicine, Queen Charlotte s and Chelsea Hospital, London, UK a
    Ultrasound Obstet Gynecol 17:203-8. 2001
    ..To apply digital imaging techniques to the quantification of placental vascularity using power Doppler...
  12. ncbi request reprint Liposomal thyroxine: a noninvasive model for transplacental fetal therapy
    R Bajoria
    Academic Department of Obstetrics and Gynecology, Charring Cross and Westminster Medical School, London, United Kingdom
    J Clin Endocrinol Metab 82:3271-7. 1997
    ..7 +/- 0.8%; P < 0.001). Our data suggest that anionic liposomes increase transplacental transfer of T4. If confirmed in vivo, liposomes may provide an alternative noninvasive method of drug delivery to the fetus...
  13. ncbi request reprint Intrauterine rescue transfusion in monochorionic multiple pregnancies with recent single intrauterine death
    S Tanawattanacharoen
    Centre for Fetal Care, Department of Maternal and Fetal Medicine, Imperial College School of Medicine, Queen Charlotte's and Chelsea Hospital, Du Cane Road, Hammersmith Hospital, London W12 0NN, UK
    Prenat Diagn 21:274-8. 2001
    ..Until its role becomes clearer, we recommend that its use be restricted to situations in which the parents and the local jurisdiction allow late termination as an option if brain injury subsequently manifests on ultrasound...
  14. ncbi request reprint In utero therapy for lower urinary tract obstruction
    S K Agarwal
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, London, UK
    Prenat Diagn 21:970-6. 2001
    ..It also discusses the limited data against which the efficacy of the various options can be assessed. The current state of fetal intervention is detailed in the present review...
  15. ncbi request reprint Transport and metabolism of thyrotrophin-releasing hormone across the fetal membrane
    R Bajoria
    Royal Postgraduate Medical School, Institute of Obstetrics and Gynaecology, Queen Charlotte s and Chelsea Hospital, London, United Kingdom
    J Clin Endocrinol Metab 82:3399-407. 1997
    ..26 +/- 1.50%; P < 0.05). These results suggest that the human fetal membrane acts as an enzymatic barrier to the bidirectional transfer of TRH from 24 weeks gestation...
  16. ncbi request reprint Caesarean section: every woman's right to choose?
    S Paterson-Brown
    Institute of Obstetrics and Gynaecology, Imperial College School of Medicine, Queen Charlotte s and Chelsea Hospital, London, UK
    Curr Opin Obstet Gynecol 9:351-5. 1997
    ....
  17. ncbi request reprint Interstitial laser: a new surgical technique for twin reversed arterial perfusion sequence in early pregnancy
    M Jolly
    Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Institute of Reproductive and Developmental Biology, Imperial College School of Medicine, London, UK
    BJOG 108:1098-102. 2001
    ..Both pregnancies continued uneventfully and each resulted in the birth of a healthy baby at term...
  18. ncbi request reprint Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow
    C Campagnoli
    Department of Maternal and Fetal Medicine, Institute of Reproductive and Developmental Biology, Imperial College School of Medicine, London, United Kingdom
    Blood 98:2396-402. 2001
    ..MSCs similar to those derived from adult bone marrow, fetal liver, and fetal bone marrow circulate in first-trimester human blood and may provide novel targets for in utero cellular and gene therapy...
  19. ncbi request reprint Effects of fetal intravenous glucose challenge in normal and growth retarded fetuses
    U Nicolini
    Royal Postgraduate Medical School, Institute of Obstetrics and Gynaecology, Queen Charlotte's Maternity Hospital, London, United Kingdom
    Horm Metab Res 22:426-30. 1990
    ..79) (P less than 0.02). These results support the concept of a low energy state in IUGR. Fetal glucose supplementation in IUGR is unlikely to be of benefit and may even exacerbate underlying acidosis...
  20. ncbi request reprint Fetal telemedicine: interactive transfer of realtime ultrasound and video via ISDN for remote consultation
    N M Fisk
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, London, UK
    J Telemed Telecare 1:38-44. 1995
    ..If confirmed, the success of this technology has implications for future referral practice in fetal medicine...
  21. ncbi request reprint Re: Intra-amniotic Doppler measurement of blood flow in placental vascular anastomoses in twin-twin transfusion syndrome
    M J O Taylor
    Ultrasound Obstet Gynecol 24:479; author reply 479-81. 2004
  22. ncbi request reprint Pseudo-arterio-arterial anastomoses in twin-twin transfusion syndrome
    M J O Taylor
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital and Institute of Reproductive and Developmental Biology, Imperial College, London, UK
    Placenta 25:742-7; discussion 748-52. 2004
    ..We applied a computer model of chorionic vessels to determine a configuration that reproduced this phenomenon...
  23. ncbi request reprint Characterisation of deep arterio-venous anastomoses within monochorionic placentae by vascular casting
    L Y Wee
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, United Kingdom
    Placenta 26:19-24. 2005
    ....
  24. ncbi request reprint Increased latency of absent end-diastolic flow in the umbilical artery of monochorionic twin fetuses
    T M Vanderheyden
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, and Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, UK
    Ultrasound Obstet Gynecol 26:44-9. 2005
    ..To determine if absent end-diastolic flow (AEDF) in the umbilical artery (UA) has a longer latency in monochorionic (MC) twin fetuses compared to singleton or dichorionic twin (DC) fetuses...
  25. ncbi request reprint High perinatal survival in monoamniotic twins managed by prophylactic sulindac, intensive ultrasound surveillance, and Cesarean delivery at 32 weeks' gestation
    L Pasquini
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, London, UK
    Ultrasound Obstet Gynecol 28:681-7. 2006
    ....
  26. ncbi request reprint Longitudinal blood flow in shared (arteriovenous anastomoses) and non-shared cotyledons in monochorionic placentae
    L Y Wee
    Experimental Fetal Medicine Group, Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, UK
    Placenta 28:516-22. 2007
    ..In this study we aimed to quantitate monochorionic twin placental blood flow in vivo through arterio-venous anastomoses (AVA) and corresponding vessels within normal cotyledons...
  27. ncbi request reprint Stage I twin-twin transfusion syndrome: rates of progression and regression in relation to outcome
    K O'Donoghue
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, London, UK
    Ultrasound Obstet Gynecol 30:958-64. 2007
    ..We investigated rates of progression and regression in Stage I TTTS and determined factors influencing the course of the disease...
  28. doi request reprint The placenta contributes to activation of the renin angiotensin system in twin-twin transfusion syndrome
    P Galea
    Experimental Fetal Medicine Group, Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, UK
    Placenta 29:734-42. 2008
    ..Given the markedly different phenotypes in the genetically identical fetuses with TTTS, we suggest that the source of RAS components may influence their clinical manifestations...
  29. ncbi request reprint Management of other complications specific to monochorionic twin pregnancies
    L Pasquini
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, Du Cane Road, Hammaersmith, W12 0HS London, UK
    Best Pract Res Clin Obstet Gynaecol 18:577-99. 2004
    ..Recent strategies to reduce the high perinatal mortality due to cord entanglement in antenatally diagnosed monoamniotic twins including medical amnioreduction and elective caesarean delivery at 32 weeks, are also discussed...
  30. ncbi request reprint Derivation of rate of arterio-arterial anastomotic transfusion between monochorionic twin fetuses by Doppler waveform analysis
    M L Denbow
    Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, United Kingdom
    Placenta 25:664-70. 2004
    ..Although AA net flows are modest, chronic unbalanced counterflow of this magnitude in the absence of compensatory superficial anastomoses could lead to significant haemodynamic compromise...
  31. ncbi request reprint Occlusion of arterio-arterial anastomosis manifesting as acute twin-twin transfusion syndrome
    T Y T Tan
    Institute of Reproductive and Developmental Biology, Imperial College, Hammersmith Campus, London, UK
    Placenta 25:238-42. 2004
    ..This case report shows that the unmasking of unbalanced AVA configurations by occlusion of a protective AAA can manifest as TTTS...
  32. pmc Influence of twin-twin transfusion syndrome on fetal cardiovascular structure and function: prospective case-control study of 136 monochorionic twin pregnancies
    A A Karatza
    Department of Maternal Fetal Medicine, Queen Charlotte s and Chelsea Hospital, Imperial College, London, UK
    Heart 88:271-7. 2002
    ..To test the hypothesis that identical twins show no inter-twin differences in cardiovascular structure or physiology in fetal life unless there has been twin-twin transfusion syndrome...
  33. ncbi request reprint Test amnioinfusion to determine suitability for serial therapeutic amnioinfusion in midtrimester premature rupture of membranes
    L K Tan
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, and Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Hammersmith Campus, London, UK
    Fetal Diagn Ther 18:183-9. 2003
    ..To evaluate whether a test amnioinfusion procedure is useful in selecting cases of midtrimester preterm premature rupture of membranes (PPROM) which may benefit from serial amnioinfusions if the initial fluid is retained...
  34. ncbi request reprint Reducing the incidence of twins and triplets
    R C Wimalasundera
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, Du Cane Road, Hammersmith, London W12 0HS, UK
    Best Pract Res Clin Obstet Gynaecol 17:309-29. 2003
    ..New developments in blastocyst culture, single embryo transfer, embryo cryopreservation and pre-implantation aneuploidy exclusion, should allow improvements in pregnancy rates without increasing multiple pregnancies...
  35. ncbi request reprint Ultrasound-guided umbilical cord occlusion using bipolar diathermy for Stage III/IV twin-twin transfusion syndrome
    M J O Taylor
    Centre for Fetal Care, Department of Maternal and Fetal Medicine, Imperial College School of Medicine, Queen Charlotte s and Chelsea Hospital, Du Cane Road, London W12 0HS, UK
    Prenat Diagn 22:70-6. 2002
    ..To evaluate bipolar diathermy as a technique for selective fetocide in the treatment of advanced (Stage III/IV) twin-twin transfusion syndrome (TTTS)...
  36. ncbi request reprint Transmitted arterio-arterial anastomosis waveforms causing cyclically intermittent absent/reversed end-diastolic umbilical artery flow in monochorionic twins
    L Y Wee
    Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital and Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, Du Cane Road, W12 0NN, London, UK
    Placenta 24:772-8. 2003
    ....
  37. ncbi request reprint Twin-to-twin transfusion syndrome results from dynamic asymmetrical reduction in placental anastomoses: a hypothesis
    N J Sebire
    Centre for Fetal Care, Department of Maternal-Fetal Medicine, Imperial College School of Medicine at Queen Charlotte's, Hammersmith Hospital Site, Du Cane Road, London, UK
    Placenta 22:383-91. 2001
    ....
  38. ncbi request reprint Validation of the Quintero staging system for twin-twin transfusion syndrome
    M J O Taylor
    Centre for Fetal Care, Department of Maternal and Fetal Medicine, Imperial College of Science, Technology and Medicine, Queen Charlotte s and Chelsea Hospital, London, United Kingdom
    Obstet Gynecol 100:1257-65. 2002
    ..To validate an established staging system for twin-twin transfusion syndrome...
  39. ncbi request reprint Amniotic fluid testosterone: relationship with cortisol and gestational age
    P Sarkar
    Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, UK
    Clin Endocrinol (Oxf) 67:743-7. 2007
    ..Although best investigated in foetal plasma, this is now difficult because of the decline in frequency of foetal blood sampling; in this study, we used amniotic fluid as a biomarker to investigate foetal exposure...
  40. ncbi request reprint FastFISH: technique for ultrarapid fluorescence in situ hybridization on uncultured amniocytes yielding results within 2 h of amniocentesis
    M Choolani
    Diagnostic Biomarker Discovery Laboratory, Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, 119074 Singapore
    Mol Hum Reprod 13:355-9. 2007
    ..FastFISH allows results to be released on the same day as amniocentesis. It represents the necessary development for a 1-day prenatal diagnosis service...
  41. ncbi request reprint Maternal anxiety at amniocentesis and plasma cortisol
    P Sarkar
    Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, UK
    Prenat Diagn 26:505-9. 2006
    ..To assess whether anticipation of amniocentesis is linked with maternal anxiety, and whether this anxiety is associated with increased maternal plasma cortisol...
  42. ncbi request reprint Histomorphometric characterisation of shared and non-shared cotyledonary villus territories of monochorionic placentae in relation to pregnancy complications
    L Y Wee
    Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, UK
    Placenta 27:475-82. 2006
    ....
  43. pmc Fetal plasma testosterone correlates positively with cortisol
    R Gitau
    Wolfson and Weston Research Centre for Family Health, Institute of Reproductive and Developmental Biology, Imperial College London, Du Cane Road, London W12 0NN, UK
    Arch Dis Child Fetal Neonatal Ed 90:F166-9. 2005
    ..Fetal exposure to testosterone has been implicated in programming childhood behaviour, but little is known about the determinants of fetal testosterone concentrations...
  44. ncbi request reprint Variable umbilical artery end-diastolic frequency is associated with arterio-arterial anastomosis
    L Y Wee
    Ultrasound Obstet Gynecol 21:626. 2003
  45. pmc Human fetal and maternal corticotrophin releasing hormone responses to acute stress
    R Gitau
    Fetal and Neonatal Stress Research Group, Wolfson and Weston Research Centre for Family Health, Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College London, London W12 0NN, UK
    Arch Dis Child Fetal Neonatal Ed 89:F29-32. 2004
    ....
  46. ncbi request reprint Standardization of power Doppler quantification of blood flow in the human fetus using the aorta and inferior vena cava
    A W Welsh
    Department of Obstetrics, Royal Prince Alfred Hospital, Camperdown, Australia
    Ultrasound Obstet Gynecol 26:33-43. 2005
    ..This study aimed to test the applicability to the fetus of mathematical techniques developed to standardize power Doppler indices of adult regional perfusion...