David Erritzoe

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi request reprint In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users
    David Erritzoe
    Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Arch Gen Psychiatry 68:562-76. 2011
  2. doi request reprint A nonlinear relationship between cerebral serotonin transporter and 5-HT(2A) receptor binding: an in vivo molecular imaging study in humans
    David Erritzoe
    Neurobiology Research Unit and PET and Cyclotron Unit, University Hospital Rigshospitalet, Copenhagen, Denmark
    J Neurosci 30:3391-7. 2010
  3. pmc Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels
    Anders Bue Klein
    Neurobiology Research Unit, The Neuroscience Center, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    J Cereb Blood Flow Metab 30:e1-7. 2010
  4. doi request reprint Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding
    Vibe G Frokjaer
    Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Copenhagen, Denmark
    Psychoneuroendocrinology 35:1311-20. 2010
  5. doi request reprint Seasonal changes in brain serotonin transporter binding in short serotonin transporter linked polymorphic region-allele carriers but not in long-allele homozygotes
    Jan Kalbitzer
    Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Biol Psychiatry 67:1033-9. 2010
  6. doi request reprint The personality trait openness is related to cerebral 5-HTT levels
    Jan Kalbitzer
    Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Denmark
    Neuroimage 45:280-5. 2009
  7. doi request reprint Serotonin2A receptor blockade and clinical effect in first-episode schizophrenia patients treated with quetiapine
    Hans Rasmussen
    Center for Neuropsychiatric Schizophrenia Research, Faculty of Health Sciences, Copenhagen University Hospital Glostrup, Copenhagen, Denmark
    Psychopharmacology (Berl) 213:583-92. 2011
  8. doi request reprint Cognitive function is related to fronto-striatal serotonin transporter levels--a brain PET study in young healthy subjects
    Karine Madsen
    The Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Psychopharmacology (Berl) 213:573-81. 2011
  9. doi request reprint Cortical and subcortical 5-HT2A receptor binding in neuroleptic-naive first-episode schizophrenic patients
    David Erritzoe
    Neurobiology Research Unit, Center for Integrated Molecular Brain Imaging, University Hospital Rigshospitalet, Copenhagen, Denmark
    Neuropsychopharmacology 33:2435-41. 2008
  10. doi request reprint Brain imaging of serotonin 4 receptors in humans with [11C]SB207145-PET
    Lisbeth Marner
    The Neuroscience Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen O, Denmark
    Neuroimage 50:855-61. 2010

Detail Information

Publications13

  1. doi request reprint In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users
    David Erritzoe
    Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Arch Gen Psychiatry 68:562-76. 2011
    ..In addition, MDMA is a potent releaser and reuptake inhibitor of presynaptic serotonin...
  2. doi request reprint A nonlinear relationship between cerebral serotonin transporter and 5-HT(2A) receptor binding: an in vivo molecular imaging study in humans
    David Erritzoe
    Neurobiology Research Unit and PET and Cyclotron Unit, University Hospital Rigshospitalet, Copenhagen, Denmark
    J Neurosci 30:3391-7. 2010
    ..That is, the observed association between the 5-HT(2A) receptor and SERT binding could be driven by the projection output from the raphe nuclei, but other explanations are also at hand...
  3. pmc Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels
    Anders Bue Klein
    Neurobiology Research Unit, The Neuroscience Center, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    J Cereb Blood Flow Metab 30:e1-7. 2010
    ..In conclusion, val66met BDNF polymorphism status is not associated with changes in the serotonergic system. Moreover, BDNF levels in blood do not correlate with either 5-HT(2A) or SERT binding...
  4. doi request reprint Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding
    Vibe G Frokjaer
    Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Copenhagen, Denmark
    Psychoneuroendocrinology 35:1311-20. 2010
    ..This study was undertaken to examine if baseline levels of endogenous sex hormones are associated with cerebral serotonin 2A (5-HT(2A)) receptor binding in men...
  5. doi request reprint Seasonal changes in brain serotonin transporter binding in short serotonin transporter linked polymorphic region-allele carriers but not in long-allele homozygotes
    Jan Kalbitzer
    Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Biol Psychiatry 67:1033-9. 2010
    ..A polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) has been associated with seasonality both in patients with seasonal affective disorder and in the general population...
  6. doi request reprint The personality trait openness is related to cerebral 5-HTT levels
    Jan Kalbitzer
    Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Denmark
    Neuroimage 45:280-5. 2009
    ..We speculate that the set-point of serotonergic signaling in an individual represents a trade-off between flexibility and vulnerability when exposed to environmental stress...
  7. doi request reprint Serotonin2A receptor blockade and clinical effect in first-episode schizophrenia patients treated with quetiapine
    Hans Rasmussen
    Center for Neuropsychiatric Schizophrenia Research, Faculty of Health Sciences, Copenhagen University Hospital Glostrup, Copenhagen, Denmark
    Psychopharmacology (Berl) 213:583-92. 2011
    ....
  8. doi request reprint Cognitive function is related to fronto-striatal serotonin transporter levels--a brain PET study in young healthy subjects
    Karine Madsen
    The Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Psychopharmacology (Berl) 213:573-81. 2011
    ..We hypothesized that higher performance on tests sensitive to serotonin would be associated with higher SERT levels in specific fronto-striatal brain regions...
  9. doi request reprint Cortical and subcortical 5-HT2A receptor binding in neuroleptic-naive first-episode schizophrenic patients
    David Erritzoe
    Neurobiology Research Unit, Center for Integrated Molecular Brain Imaging, University Hospital Rigshospitalet, Copenhagen, Denmark
    Neuropsychopharmacology 33:2435-41. 2008
    ..However, a preliminary finding of increased 5-HT(2A) binding in the caudate nucleus requires further investigation to explore the relation of subcortical and cortical 5-HT(2A) receptor binding...
  10. doi request reprint Brain imaging of serotonin 4 receptors in humans with [11C]SB207145-PET
    Lisbeth Marner
    The Neuroscience Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen O, Denmark
    Neuroimage 50:855-61. 2010
    ..In conclusion, the 5-HT(4) receptor binding in human brain can be reliably assessed with [(11)C]SB207145, which is encouraging for future PET studies of drug occupancy or patients with neuropsychiatric disorders...
  11. doi request reprint Simultaneous polysubstance use among Danish 3,4-methylenedioxymethamphetamine and hallucinogen users: combination patterns and proposed biological bases
    Cecilie L Licht
    Neurobiology Research Unit NRU and Center for Integrated Molecular Brain Imaging Cimbi, University of Copenhagen and Rigshospitalet, Copenhagen, Denmark
    Hum Psychopharmacol 27:352-63. 2012
    ..To describe patterns of simultaneous polysubstance use (SPU) among Danish 3,4-methylenedioxymethamphetamine (MDMA) ("Ecstasy") and hallucinogen users...
  12. doi request reprint Serotonin transporter binding in the hypothalamus correlates negatively with tonic heat pain ratings in healthy subjects: a [11C]DASB PET study
    Ron Kupers
    Section for Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Neuroimage 54:1336-43. 2011
    ..The negative correlation between SERT binding in the hypothalamus and insula with tonic pain ratings suggests a possible serotonergic control of the role of these areas in the modulation or in the affective appreciation of pain...
  13. doi request reprint A probabilistic approach to delineating functional brain regions
    Jan Kalbitzer
    Neurobiology Research Unit, Copenhagen University Hospital, Copenhagen, Denmark
    J Nucl Med Technol 37:91-5. 2009
    ..The case is made for the raphé nuclei, a collection of nuclei situated in the brain stem known to be densely packed with serotonin transporters (5-hydroxytryptaminic [5-HTT] system)...