Christl A Donnelly

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. pmc Rabies and canine distemper virus epidemics in the red fox population of northern Italy (2006-2010)
    Pierre Nouvellet
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS ONE 8:e61588. 2013
  2. pmc The duration of the effects of repeated widespread badger culling on cattle tuberculosis following the cessation of culling
    Helen E Jenkins
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS ONE 5:e9090. 2010
  3. pmc A comparative epidemiologic analysis of SARS in Hong Kong, Beijing and Taiwan
    Eric H Y Lau
    School of Public Health, The University of Hong Kong, Pokfulam Road, Hong Kong
    BMC Infect Dis 10:50. 2010
  4. pmc Late-acting dominant lethal genetic systems and mosquito control
    Hoang Kim Phuc
    Department of Zoology, University of Oxford, South Parks Road, Oxford, UK
    BMC Biol 5:11. 2007
  5. ncbi request reprint Positive and negative effects of widespread badger culling on tuberculosis in cattle
    Christl A Donnelly
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Nature 439:843-6. 2006
  6. ncbi request reprint Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong
    Christl A Donnelly
    Department of Infectious Disease Epidemiology, Imperial College, London, UK
    Lancet 361:1761-6. 2003
  7. ncbi request reprint Extending backcalculation to analyse BSE data
    C A Donnelly
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, UK
    Stat Methods Med Res 12:177-90. 2003
  8. ncbi request reprint Gender difference in HIV-1 RNA viral loads
    C A Donnelly
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, UK
    HIV Med 6:170-8. 2005
  9. ncbi request reprint Epidemiological and genetic analysis of severe acute respiratory syndrome
    Christl A Donnelly
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, UK
    Lancet Infect Dis 4:672-83. 2004
  10. ncbi request reprint Impact of localized badger culling on tuberculosis incidence in British cattle
    Christl A Donnelly
    Independent Scientific Group on Cattle TB, c o Department for Environment, Food and Rural Affairs, 1A Page Street, London SW1P 4PQ, UK
    Nature 426:834-7. 2003

Detail Information

Publications79

  1. pmc Rabies and canine distemper virus epidemics in the red fox population of northern Italy (2006-2010)
    Pierre Nouvellet
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS ONE 8:e61588. 2013
    ..This was confirmed by field observations. Finally we discuss the implications for the eco-epidemiological dynamics of both epidemics in relation to control measures...
  2. pmc The duration of the effects of repeated widespread badger culling on cattle tuberculosis following the cessation of culling
    Helen E Jenkins
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS ONE 5:e9090. 2010
    ..However, a full assessment of the utility of badger culling requires information on the duration of culling effects...
  3. pmc A comparative epidemiologic analysis of SARS in Hong Kong, Beijing and Taiwan
    Eric H Y Lau
    School of Public Health, The University of Hong Kong, Pokfulam Road, Hong Kong
    BMC Infect Dis 10:50. 2010
    ..The aim of this study is to identify similarities and differences in SARS epidemiology in three populations with similar host and viral genotype...
  4. pmc Late-acting dominant lethal genetic systems and mosquito control
    Hoang Kim Phuc
    Department of Zoology, University of Oxford, South Parks Road, Oxford, UK
    BMC Biol 5:11. 2007
    ..Additionally, vector populations with strong density-dependent effects will tend to be resistant to SIT-based control as the population-reducing effect of induced sterility will tend to be offset by reduced density-dependent mortality...
  5. ncbi request reprint Positive and negative effects of widespread badger culling on tuberculosis in cattle
    Christl A Donnelly
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Nature 439:843-6. 2006
    ..These findings are biologically consistent with previous studies but will present challenges for policy development...
  6. ncbi request reprint Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong
    Christl A Donnelly
    Department of Infectious Disease Epidemiology, Imperial College, London, UK
    Lancet 361:1761-6. 2003
    ..We assessed the epidemiology of SARS in Hong Kong...
  7. ncbi request reprint Extending backcalculation to analyse BSE data
    C A Donnelly
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, UK
    Stat Methods Med Res 12:177-90. 2003
    ..Finally, future directions of epidemiological analysis of BSE epidemics are discussed taking into account ongoing developments in the science of BSE and possible changes in BSE-related policies...
  8. ncbi request reprint Gender difference in HIV-1 RNA viral loads
    C A Donnelly
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, UK
    HIV Med 6:170-8. 2005
    ..To test and characterize the dependence of viral load on gender in different countries and racial groups as a function of CD4 T-cell count...
  9. ncbi request reprint Epidemiological and genetic analysis of severe acute respiratory syndrome
    Christl A Donnelly
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, UK
    Lancet Infect Dis 4:672-83. 2004
    ....
  10. ncbi request reprint Impact of localized badger culling on tuberculosis incidence in British cattle
    Christl A Donnelly
    Independent Scientific Group on Cattle TB, c o Department for Environment, Food and Rural Affairs, 1A Page Street, London SW1P 4PQ, UK
    Nature 426:834-7. 2003
    ..Here we present results from a large-scale field trial that indicate that localized badger culling not only fails to control but also seems to increase TB incidence in cattle...
  11. ncbi request reprint Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial
    Christl A Donnelly
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, Norfolk Place, London W2 1PG, UK
    Int J Infect Dis 11:300-8. 2007
    ..Failure to control the infection has been linked to transmission from European badgers; badger culling has therefore formed a component of British TB control policy since 1973...
  12. pmc Serial intervals and the temporal distribution of secondary infections within households of 2009 pandemic influenza A (H1N1): implications for influenza control recommendations
    Christl A Donnelly
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    Clin Infect Dis 52:S123-30. 2011
    ..These results will inform future recommendations on duration of isolation of individuals with ILI...
  13. ncbi request reprint Transmission dynamics of the etiological agent of SARS in Hong Kong: impact of public health interventions
    Steven Riley
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, Exhibition Road, London SW7 2AZ, UK
    Science 300:1961-6. 2003
    ..We estimate that most currently infected persons are now hospitalized, which highlights the importance of control of nosocomial transmission...
  14. ncbi request reprint Evolution in a multi-host parasite: chronobiological circadian rhythm and population genetics of Schistosoma japonicum cercariae indicates contrasting definitive host reservoirs by habitat
    Da Bing Lu
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, Norfolk Place, London W2 1PG, UK
    Int J Parasitol 39:1581-8. 2009
    ..Such parasite diversity could, in turn, provide an explanation for the different infection scenarios observed between the two regions, and hence have important applied implications in terms of targeted control of key reservoirs...
  15. pmc Epidemiology, transmission dynamics and control of SARS: the 2002-2003 epidemic
    Roy M Anderson
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Philos Trans R Soc Lond B Biol Sci 359:1091-105. 2004
    ..These lessons learnt from the SARS experience are presented in an epidemiological and public health context...
  16. pmc The impact of single versus mixed schistosome species infections on liver, spleen and bladder morbidity within Malian children pre- and post-praziquantel treatment
    Artemis Koukounari
    Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, UK
    BMC Infect Dis 10:227. 2010
    ..Mixed infections might generate synergistic or antagonistic interactions and thereby clinically affect individuals and/or impact parasite epidemiology...
  17. pmc Transmission of Schistosoma japonicum in marshland and hilly regions of China: parasite population genetic and sibship structure
    Da Bing Lu
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, UK
    PLoS Negl Trop Dis 4:e781. 2010
    ..Such results suggest a different transmission process within the hilly region from within the marshlands. Moreover, this is the first time that the sibling relationship analysis was applied to the transmission dynamics for S. japonicum...
  18. ncbi request reprint Short-term projections for variant Creutzfeldt-Jakob disease onsets
    Azra C Ghani
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, UK
    Stat Methods Med Res 12:191-201. 2003
    ..These results demonstrate the continued uncertainty in the future scale of this disease...
  19. pmc Factors determining the pattern of the variant Creutzfeldt-Jakob disease (vCJD) epidemic in the UK
    Azra C Ghani
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, Norfolk Place, London W2 1PG, UK
    Proc Biol Sci 270:689-98. 2003
    ....
  20. ncbi request reprint Public health. Public health risk from the avian H5N1 influenza epidemic
    Neil M Ferguson
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Science 304:968-9. 2004
  21. pmc Integrated monitoring and evaluation and environmental risk factors for urogenital schistosomiasis and active trachoma in Burkina Faso before preventative chemotherapy using sentinel sites
    Artemis Koukounari
    Schistosomiasis Control Initiative, Department of Infectious Diseases Epidemiology, St Mary s Campus, Faculty of Medicine, Imperial College London, UK
    BMC Infect Dis 11:191. 2011
    ....
  22. pmc Household transmission of 2009 pandemic influenza A (H1N1) virus in the United States
    Simon Cauchemez
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London
    N Engl J Med 361:2619-27. 2009
    ..Risk factors for transmission remain largely uncharacterized. We characterize the risk factors and describe the transmission of the virus within households...
  23. pmc Implications of BSE infection screening data for the scale of the British BSE epidemic and current European infection levels
    Christl A Donnelly
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College of Science, Technology and Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Proc Biol Sci 269:2179-90. 2002
    ..Infection incidence for cattle born after mid-1996 was highest in Greece, Italy and Belgium, with Spain and The Netherlands having intermediate levels, and estimates for Great Britain, Germany and France being comparably low...
  24. doi request reprint The effects of annual widespread badger culls on cattle tuberculosis following the cessation of culling
    Helen E Jenkins
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, Norfolk Place, London W2 1PG, UK
    Int J Infect Dis 12:457-65. 2008
    ....
  25. pmc Monitoring trends in HIV prevalence among young people, aged 15 to 24 years, in Manicaland, Zimbabwe
    Kimberly A Marsh
    Department of Infectious Disease Epidemiology, Imperial College London, UK
    J Int AIDS Soc 14:27. 2011
    ..Changes in socio-demographic characteristics and reported sexual behaviour are investigated...
  26. ncbi request reprint Schistosoma haematobium infection and morbidity before and after large-scale administration of praziquantel in Burkina Faso
    Artemis Koukounari
    Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, Imperial College London, London, W2 1PG, United Kingdom
    J Infect Dis 196:659-69. 2007
    ..In sub-Saharan Africa, 112 million people are infected with Schistosoma haematobium, with the most intense infections in children 5-15 years old...
  27. ncbi request reprint Evaluating the proximate determinants framework for HIV infection in rural Zimbabwe
    James J C Lewis
    London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    Sex Transm Infect 83:i61-69. 2007
    ..One suggested solution has been a proximate determinants framework, in which risk factors are grouped into "underlying", "proximate" and "biological" determinants...
  28. doi request reprint Contrasting reservoirs for Schistosoma japonicum between marshland and hilly regions in Anhui, China--a two-year longitudinal parasitological survey
    Da Bing Lu
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, Norfolk Place, London W2 1PG, UK
    Parasitology 137:99-110. 2010
    ..Such results may have implications for the current human- and bovine-oriented control policy for this medically and veterinarily important disease, particularly within the hilly regions of mainland China...
  29. ncbi request reprint Viral replication under combination antiretroviral therapy: a comparison of four different regimens
    Azra C Ghani
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College of Science, Technology and Medicine, London, UK
    J Acquir Immune Defic Syndr 30:167-76. 2002
    ..04; 95% CI, 1.0-1.07). Measurement of viral load after approximately 7 days provided the most accurate measure of the degree of viral suppression induced by a given drug regimen...
  30. doi request reprint Implications of a circulating vaccine-derived poliovirus in Nigeria
    Helen E Jenkins
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom
    N Engl J Med 362:2360-9. 2010
    ....
  31. pmc Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility
    Simon Cauchemez
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    Lancet Infect Dis 14:50-6. 2014
    ..We analysed epidemiological and genetic data to assess the extent of human infection, the performance of case detection, and the transmission potential of MERS-CoV with and without control measures...
  32. pmc Localized reactive badger culling increases risk of bovine tuberculosis in nearby cattle herds
    Flavie Vial
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    Biol Lett 8:50-3. 2012
    ..Such findings may partly explain why some earlier localized approaches to bTB control were ineffective...
  33. pmc Updated projections of future vCJD deaths in the UK
    Azra C Ghani
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Norfolk Place, London W2 1PG, UK
    BMC Infect Dis 3:4. 2003
    ..However, recent vCJD case data have indicated a decrease in the annual incidence of deaths over the past two years...
  34. pmc A statistical model of the international spread of wild poliovirus in Africa used to predict and prevent outbreaks
    Kathleen M O'Reilly
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
    PLoS Med 8:e1001109. 2011
    ..A quantitative understanding of the factors that predict the distribution and timing of outbreaks will enable their prevention and facilitate the completion of global eradication...
  35. ncbi request reprint Assessment of ultrasound morbidity indicators of schistosomiasis in the context of large-scale programs illustrated with experiences from Malian children
    Artemis Koukounari
    Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, UK
    Am J Trop Med Hyg 75:1042-52. 2006
    ..mansoni infection. We conclude that ultrasonography should be included in large-scale control interventions, where logistics allow, but cautiously...
  36. pmc Assessment of the risk posed by bovine spongiform encephalopathy in cattle in Great Britain and the impact of potential changes to current control measures
    Neil M Ferguson
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Proc Biol Sci 270:1579-84. 2003
    ..04 additional vCJD deaths over the next 60 years. However, there is substantial (more than 40-fold) uncertainty surrounding this estimate, the sources of which are discussed...
  37. ncbi request reprint Bovine spongiform encephalopathy in the United States--an epidemiologist's view
    Christl A Donnelly
    Department of Infectious Disease Epidemiology, Imperial College, London
    N Engl J Med 350:539-42. 2004
  38. pmc HIV-1 transmitting couples have similar viral load set-points in Rakai, Uganda
    T Deirdre Hollingsworth
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Pathog 6:e1000876. 2010
    ..The most parsimonious explanation is that this is due to shared characteristics of the transmitted virus, a finding which sheds light on both the role of viral factors in HIV-1 pathogenesis and on the evolution of the virus...
  39. ncbi request reprint Comparison of the risks of atherosclerotic events versus death from other causes associated with antiretroviral use
    Grace P S Kwong
    Department of Infectious Disease Epidemiology, Imperial College London, UK
    AIDS 20:1941-50. 2006
    ..Studies considering the risk of atherosclerotic disease (AtD) associated with the use of HAART have reported inconsistent results...
  40. doi request reprint Estimating risk over time using data from targeted surveillance systems: application to bovine tuberculosis in Great Britain
    Isobel M Blake
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
    Epidemics 4:179-86. 2012
    ..We show that for an increasing underlying incidence trend, the current Defra approach can produce artefactual fluctuations whereas the alternative method described provides more accurate descriptions of the underlying risks over time...
  41. pmc Essential epidemiological mechanisms underpinning the transmission dynamics of seasonal influenza
    James Truscott
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College, London W2 1PG, UK
    J R Soc Interface 9:304-12. 2012
    ..We discuss our findings in the context of other work fitting to seasonal influenza data...
  42. ncbi request reprint The transmission dynamics of BSE and vCJD
    Azra C Ghani
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College of Science, Technology and Medicine St Mary s, Norfolk Place, London W2 1PG, UK
    C R Biol 325:37-47. 2002
    ..We also consider the epidemiological determinants of the future course of the vCJD epidemic, including the age and genetic characteristics of the confirmed cases, and present predictions of future case numbers...
  43. pmc Sensitivities and specificities of diagnostic tests and infection prevalence of Schistosoma haematobium estimated from data on adults in villages northwest of Accra, Ghana
    Artemis Koukounari
    Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, United Kingdom
    Am J Trop Med Hyg 80:435-41. 2009
    ..Furthermore, microscopy and hematuria dipsticks were indicated through these models as the most appropriate techniques for detection of S. haematobium infection...
  44. pmc Pandemic potential of a strain of influenza A (H1N1): early findings
    Christophe Fraser
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, Faculty of Medicine, Norfolk Place, London W2 1PG, UK
    Science 324:1557-61. 2009
    ..Transmissibility is therefore substantially higher than that of seasonal flu, and comparable with lower estimates of R0 obtained from previous influenza pandemics...
  45. pmc Local cattle and badger populations affect the risk of confirmed tuberculosis in British cattle herds
    Flavie Vial
    Department of Infectious Disease Epidemiology, MRC Centre for Outbreak Analysis and Modelling, School of Public Health, Imperial College London, London, United Kingdom
    PLoS ONE 6:e18058. 2011
    ....
  46. doi request reprint Genetic diversity of Schistosoma japonicum miracidia from individual rodent hosts
    Da Bing Lu
    Department of Epidemiology and Statistics, School of Public Health, Medical College of Soochow University, Suzhou 215123, China
    Int J Parasitol 41:1371-6. 2011
    ..japonicum compared with other schistosomes, were proposed to explain the observed results and practical implications for control strategies are recommended...
  47. pmc A latent markov modelling approach to the evaluation of circulating cathodic antigen strips for schistosomiasis diagnosis pre- and post-praziquantel treatment in Uganda
    Artemis Koukounari
    MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom Department of Statistics, London School of Economics and Political Science, London, United Kingdom
    PLoS Comput Biol 9:e1003402. 2013
    ..mansoni infection, although additional diagnostic tools should be incorporated in schistosomiasis elimination programs. ..
  48. ncbi request reprint Robust parameter estimation techniques for stochastic within-host macroparasite models
    Steven Riley
    Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, W2 1PG London, UK
    J Theor Biol 225:419-30. 2003
    ..This indicates that the observed aggregation of parasite load may be dynamically generated by random variation in the development of an effective immune response against parasite larvae...
  49. ncbi request reprint BSE in France: epidemiological analysis and predictions
    Christl A Donnelly
    Department of Infectious Disease Epidemiology, Division of Primary Care and Population Health Sciences, Faculty of Medicine, Imperial College, Norfolk Place, London W2 1PG, United Kingdom
    C R Biol 325:793-806. 2002
    ..The results reveal that thousands of French cattle were infected with BSE over the course of the epidemic. However, case incidence is predicted to decline in future years...
  50. pmc Herd-level risk factors associated with tuberculosis breakdowns among cattle herds in England before the 2001 foot-and-mouth disease epidemic
    W T Johnston
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Biol Lett 1:53-6. 2005
    ..Spreading artificial fertilizers or farmyard manure on grazing land were both associated with decreased risk. These first case-control results from the RBCT will be followed by similar analyses as more data become available...
  51. ncbi request reprint Estimating the human health risk from possible BSE infection of the British sheep flock
    N M Ferguson
    Department of Infectious Disease Epidemiology, Imperial College of Science, Technology and Medicine, St Mary s Campus, London, UK
    Nature 415:420-4. 2002
    ....
  52. pmc The prevalence, distribution and severity of detectable pathological lesions in badgers naturally infected with Mycobacterium bovis
    H E Jenkins
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, UK
    Epidemiol Infect 136:1350-61. 2008
    ..However, the predominance of lesions in the respiratory tract indicates that most transmission occurs by the respiratory route...
  53. pmc Parasites as causative agents of human affective disorders? The impact of anti-psychotic, mood-stabilizer and anti-parasite medication on Toxoplasma gondii's ability to alter host behaviour
    J P Webster
    Department of Zoology, University of Oxford South Parks Road, Oxford OX1 3SY, UK
    Proc Biol Sci 273:1023-30. 2006
    ..gondii drugs in preventing such behavioural alterations. Our results have important implications regarding the aetiology and treatment of such disorders...
  54. pmc Patterns of uptake of treatment for self reported sexually transmitted infection symptoms in rural Zimbabwe
    J J C Lewis
    Department of Infectious Disease Epidemiology, Imperial College London, Faculty of Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Sex Transm Infect 81:326-32. 2005
    ..To determine the extent of self reported symptoms perceived to be related to sexually transmitted infections and the patterns of subsequent treatment seeking behaviour in a predominantly rural population of Zimbabwe...
  55. ncbi request reprint Comparison of the effectiveness of non-nucleoside reverse transcriptase inhibitor-containing and protease inhibitor-containing regimens using observational databases
    A C Ghani
    Department of Infectious Disease Epidemiology, Imperial College School of Medicine, London, UK
    AIDS 15:1133-42. 2001
    ..To compare the effectiveness of first protease inhibitor (PI)-containing and non-nucleoside reverse transcriptase inhibitor (NNRTI)-containing regimens...
  56. pmc The development of an age-structured model for trachoma transmission dynamics, pathogenesis and control
    Manoj Gambhir
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Negl Trop Dis 3:e462. 2009
    ..We present an age-structured mathematical model of trachoma transmission and disease to predict the impact of interventions on the prevalence of blinding trachoma...
  57. pmc Low diversity Cryptococcus neoformans variety grubii multilocus sequence types from Thailand are consistent with an ancestral African origin
    Sitali P Simwami
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom
    PLoS Pathog 7:e1001343. 2011
    ..96 - 27,177.76). Further high-density sampling of global Cng STs is now necessary to resolve the temporal sequence underlying the global emergence of this human pathogen...
  58. ncbi request reprint Mathematical biology and medical statistics: contributions to the understanding of AIDS epidemiology
    C A Donnelly
    Department of Infectious Disease Epidemiology, Imperial College School of Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Stat Methods Med Res 10:141-54. 2001
    ..The different kinds of data involved are critically compared. Some studies of the incubation period are briefly reviewed and some comments made on the role of adherence to therapy...
  59. ncbi request reprint The foot-and-mouth epidemic in Great Britain: pattern of spread and impact of interventions
    N M Ferguson
    Department of Infectious Disease Epidemiology, Imperial College School of Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Science 292:1155-60. 2001
    ..Culling is predicted to be more effective than vaccination...
  60. ncbi request reprint Transmission intensity and impact of control policies on the foot and mouth epidemic in Great Britain
    N M Ferguson
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College of Science, Technology and Medicine, St Mary s Campus, London, UK
    Nature 413:542-8. 2001
    ....
  61. doi request reprint Effectiveness of immunization against paralytic poliomyelitis in Nigeria
    Helen E Jenkins
    Medical Research Council Centre for Outbreak Analysis and Modeling, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom
    N Engl J Med 359:1666-74. 2008
    ..Understanding the relative contribution of these vaccines and the improved coverage to the decline in incident cases is essential for future planning...
  62. pmc Creating and validating an algorithm to measure AIDS mortality in the adult population using verbal autopsy
    Ben A Lopman
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    PLoS Med 3:e312. 2006
    ..A reliable tool that is independent of HIV status is needed for measuring the frequency of AIDS deaths and ultimately the impact of antiretroviral therapy on mortality...
  63. ncbi request reprint Surrogate markers for disease progression in treated HIV infection
    A C Ghani
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College School of Science, Technology, and Medicine, London, UK
    J Acquir Immune Defic Syndr 28:226-31. 2001
    ..To characterize the relationships among highly active antiretroviral therapy (HAART), HIV-1 RNA levels, immune system markers, and clinical outcome in a cohort of HIV-1-infected homosexual men...
  64. pmc Adherence to antiretroviral therapy and its impact on clinical outcome in HIV-infected patients
    N M Ferguson
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, Norfolk Place, London W2 1PG, UK
    J R Soc Interface 2:349-63. 2005
    ....
  65. ncbi request reprint Patterns of antiretroviral use in the United States of America: analysis of three observational databases
    A C Ghani
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College of Science, Technology and Medicine, London, UK
    HIV Med 4:24-32. 2003
    ..To characterize patterns of antiretroviral use in HIV-infected patients and explore variation by patient characteristics and disease stage...
  66. ncbi request reprint Morbidity indicators of Schistosoma mansoni: relationship between infection and anemia in Ugandan schoolchildren before and after praziquantel and albendazole chemotherapy
    Artemis Koukounari
    Schistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom
    Am J Trop Med Hyg 75:278-86. 2006
    ..834 g/dL after treatment was found. Our results suggest that anemia is associated with schistosomiasis and hookworm in Ugandan children and that such anemia shows a significant improvement after chemotherapy...
  67. ncbi request reprint Beer halls as a focus for HIV prevention activities in rural Zimbabwe
    James J C Lewis
    Department of Infectious Disease Epidemiology, Imperial College Faculty of Medicine, London, UK
    Sex Transm Dis 32:364-9. 2005
    ..The authors conducted an assessment of the role of beer halls in the HIV epidemic of rural Zimbabwe as part of the ongoing identification of risky places for the targeting of prevention activities...
  68. pmc Epidemiological analysis of data for scrapie in Great Britain
    T J Hagenaars
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London, UK
    Epidemiol Infect 134:359-67. 2006
    ..We show that the data analysed are consistent with the within-flock reproduction number of scrapie lying in the range 1.5-6, consistent with previous epidemiological studies...
  69. pmc Dynamics of a scrapie outbreak in a flock of Romanov sheep--estimation of transmission parameters
    T J Hagenaars
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Marys Campus, Norfolk Place, London W2 1PG
    Epidemiol Infect 131:1015-22. 2003
    ....
  70. ncbi request reprint Review of foot-and-mouth disease virus survival in animal excretions and on fomites
    L M Bartley
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, University of London, St Mary s Campus, Norfolk Place, London W2 1PG
    Vet Rec 151:667-9. 2002
  71. ncbi request reprint Methods for estimating the case fatality ratio for a novel, emerging infectious disease
    A C Ghani
    Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
    Am J Epidemiol 162:479-86. 2005
    ..They demonstrate the importance of patient characteristics regarding outcome by analyzing subgroups defined by age at admission to the hospital...
  72. ncbi request reprint The seasonal pattern of dengue in endemic areas: mathematical models of mechanisms
    L M Bartley
    Department of Infectious Disease Epidemiology, Imperial College, Faculty of Medicine, Norfolk Place, London W2 1PG, UK
    Trans R Soc Trop Med Hyg 96:387-97. 2002
    ..It was changes in such parameters (vector biting and mortality rate) which caused seasonal prevalence, but the timing of peak prevalence was a result of time delays within the system...
  73. ncbi request reprint Spatial heterogeneity and the persistence of infectious diseases
    T J Hagenaars
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    J Theor Biol 229:349-59. 2004
    ..The observed patterns are interpreted in terms of rescue effects for strong spatial heterogeneity and in terms of between-patch coherence and synchronization effects at intermediate and weak levels of heterogeneity...
  74. pmc Detecting emerging transmissibility of avian influenza virus in human households
    Michiel van Boven
    Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
    PLoS Comput Biol 3:e145. 2007
    ..We discuss the applicability of our method for the detection of emerging human-to-human transmission of avian influenza viruses in particular, and for the analysis of within-household infection data in general...
  75. ncbi request reprint The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: an analysis of all 1755 patients
    Gabriel M Leung
    University of Hong Kong, Government of the Hong Kong Special Administrative Region, and Hong Kong Hospital Authority, Hong Kong, China
    Ann Intern Med 141:662-73. 2004
    ..As yet, no one has written a comprehensive epidemiologic account of a severe acute respiratory syndrome (SARS) outbreak from an affected country...
  76. pmc Culling and cattle controls influence tuberculosis risk for badgers
    Rosie Woodroffe
    Department of Wildlife, Fish, and Conservation Biology, University of California Davis, One Shields Avenue, Davis, CA 95616, USA
    Proc Natl Acad Sci U S A 103:14713-7. 2006
    ..Our findings highlight the need for policymakers to consider multiple transmission routes when managing multihost pathogens...
  77. ncbi request reprint Non-parametric estimation of the case fatality ratio with competing risks data: an application to Severe Acute Respiratory Syndrome (SARS)
    Nicholas P Jewell
    Division of Biostatistics and Department of Statistics, University of California, Berkeley, USA
    Stat Med 26:1982-98. 2007
    ..These issues are investigated here for non-parametric estimators of F(1) and F(2). The ideas are illustrated on case fatality data for individuals infected with Severe Acute Respiratory Syndrome (SARS) in Hong Kong in 2003...
  78. pmc Simple model for tuberculosis in cattle and badgers
    D R Cox
    Nuffield College, New Road, Oxford OX1 1NF, United Kingdom
    Proc Natl Acad Sci U S A 102:17588-93. 2005
    ..1. The implications for controlling the disease are discussed...
  79. ncbi request reprint Chicken welfare is influenced more by housing conditions than by stocking density
    Marian Stamp Dawkins
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Nature 427:342-4. 2004
    ..Our results show that differences among producers in the environment that they provide for chickens have more impact on welfare than has stocking density itself...