Paul Cullinan

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. pmc Outcome of occupational asthma after cessation of exposure: a systematic review
    George Rachiotis
    Department of Occupational and Environmental Medicine, Imperial College NHLI, 1B Manresa Road, London SW3 6LR, UK
    Thorax 62:147-52. 2007
  2. ncbi request reprint Allergen and dust exposure as determinants of work-related symptoms and sensitization in a cohort of flour-exposed workers; a case-control analysis
    P Cullinan
    Department of Occupational and Environmental Medicine, Imperial College, NHLI, SW3 6LR, London, UK
    Ann Occup Hyg 45:97-103. 2001
  3. doi request reprint Occupational asthma
    Paul Cullinan
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College, 1B Manresa Road, London SW3 6LR, UK
    Occup Environ Med 65:151. 2008
  4. pmc Epidemiological assessment of health effects from chemical incidents
    Paul Cullinan
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, London, UK
    Occup Environ Med 59:568-72; quiz 572,516. 2002
  5. pmc Early allergen exposure, skin prick responses, and atopic wheeze at age 5 in English children: a cohort study
    P Cullinan
    Department of Occupational and Environmental Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, Manresa Road, London SW3 6LR, UK
    Thorax 59:855-61. 2004
  6. ncbi request reprint The prevention of occupational asthma
    P Cullinan
    Dept of Occupational and Environmental Medicine, Imperial College NHLI, London, UK
    Eur Respir J 22:853-60. 2003
  7. ncbi request reprint Can early infection explain the sibling effect in adult atopy?
    P Cullinan
    Dept of Occupational and Environmental Medicine, Imperial College School of Medicine NHLI, London, UK
    Eur Respir J 22:956-61. 2003
  8. pmc Early prescriptions of antibiotics and the risk of allergic disease in adults: a cohort study
    P Cullinan
    Department of Occupational and Environmental Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, UK
    Thorax 59:11-5. 2004
  9. ncbi request reprint Modified Th2 responses at high-dose exposures to allergen: using an occupational model
    Hayley Jeal
    Department of Occupational and Environmental Medicine, Faculty of Medicine, Imperial College NHLI, London, United Kingdom
    Am J Respir Crit Care Med 174:21-5. 2006
  10. doi request reprint Epidemiological measures of childhood asthma: cross-sectional and longitudinal consistency
    Cristina Canova
    MRC HPA Centre for Environment and Health, Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, Emmanuel Kaye Building, Manresa Road, Imperial College, London SW3 6LR, UK
    Respir Med 106:1226-35. 2012

Detail Information

Publications39

  1. pmc Outcome of occupational asthma after cessation of exposure: a systematic review
    George Rachiotis
    Department of Occupational and Environmental Medicine, Imperial College NHLI, 1B Manresa Road, London SW3 6LR, UK
    Thorax 62:147-52. 2007
    ..Patients with occupational asthma, and their medical advisers, need valid information about the prognosis of their disease...
  2. ncbi request reprint Allergen and dust exposure as determinants of work-related symptoms and sensitization in a cohort of flour-exposed workers; a case-control analysis
    P Cullinan
    Department of Occupational and Environmental Medicine, Imperial College, NHLI, SW3 6LR, London, UK
    Ann Occup Hyg 45:97-103. 2001
    ..To estimate the incidence of specific IgE sensitization and allergic respiratory symptoms among UK bakery and flour mill workers; and to examine the roles of flour aeroallergen and total dust exposures in determining these outcomes...
  3. doi request reprint Occupational asthma
    Paul Cullinan
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College, 1B Manresa Road, London SW3 6LR, UK
    Occup Environ Med 65:151. 2008
  4. pmc Epidemiological assessment of health effects from chemical incidents
    Paul Cullinan
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, London, UK
    Occup Environ Med 59:568-72; quiz 572,516. 2002
  5. pmc Early allergen exposure, skin prick responses, and atopic wheeze at age 5 in English children: a cohort study
    P Cullinan
    Department of Occupational and Environmental Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, Manresa Road, London SW3 6LR, UK
    Thorax 59:855-61. 2004
    ..There are, however, few prospective data in support. We aimed to examine this relationship in a representative cohort of children born in Ashford, Kent (UK)...
  6. ncbi request reprint The prevention of occupational asthma
    P Cullinan
    Dept of Occupational and Environmental Medicine, Imperial College NHLI, London, UK
    Eur Respir J 22:853-60. 2003
    ..Considerably more cooperation between scientists in the field, regulatory authorities and industry is required...
  7. ncbi request reprint Can early infection explain the sibling effect in adult atopy?
    P Cullinan
    Dept of Occupational and Environmental Medicine, Imperial College School of Medicine NHLI, London, UK
    Eur Respir J 22:956-61. 2003
    ..The findings support the suggestion that the "sibling effect" in atopy may not simply reflect protection by early infection...
  8. pmc Early prescriptions of antibiotics and the risk of allergic disease in adults: a cohort study
    P Cullinan
    Department of Occupational and Environmental Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, UK
    Thorax 59:11-5. 2004
    ..It is frequently asserted that antibiotic prescriptions in childhood are associated with the development of allergic disease, especially asthma. A study was undertaken to establish the direction of this relationship...
  9. ncbi request reprint Modified Th2 responses at high-dose exposures to allergen: using an occupational model
    Hayley Jeal
    Department of Occupational and Environmental Medicine, Faculty of Medicine, Imperial College NHLI, London, United Kingdom
    Am J Respir Crit Care Med 174:21-5. 2006
    ..quot; Attenuation of risk of allergy and asthma at high exposure levels has been reported in longitudinal studies of both childhood and occupational asthma...
  10. doi request reprint Epidemiological measures of childhood asthma: cross-sectional and longitudinal consistency
    Cristina Canova
    MRC HPA Centre for Environment and Health, Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, Emmanuel Kaye Building, Manresa Road, Imperial College, London SW3 6LR, UK
    Respir Med 106:1226-35. 2012
    ..We compared different definitions of childhood asthma, identified characteristics that might have influenced their accuracy and an acquisition of an 'asthma' label in wheezy and treated children...
  11. doi request reprint A large-scale, consortium-based genomewide association study of asthma
    Miriam F Moffatt
    National Heart and Lung Institute, Imperial College, London, United Kingdom
    N Engl J Med 363:1211-21. 2010
    ..Genetic risk factors may be useful in identifying subtypes of asthma and determining whether intermediate phenotypes, such as elevation of the total serum IgE level, are causally linked to disease...
  12. pmc Recorded infections and antibiotics in early life: associations with allergy in UK children and their parents
    Jessica M Harris
    Occupational and Environmental Medicine, Imperial College School of Medicine NHLI, Manresa Road, London SW3 6LR, UK
    Thorax 62:631-7. 2007
    ..It is suggested that the inverse relationship between allergic disease and family size reflects reduced exposure to early life infections, and that antibiotic treatment in childhood diminishes any protective effect of such infection...
  13. doi request reprint Asthma and occupation in the 1958 birth cohort
    Rebecca Elisabeth Ghosh
    Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, Imperial College London and MRC HPA Centre for Environment and Health, Imperial College, London, UK
    Thorax 68:365-71. 2013
    ..To examine the association of adult onset asthma with lifetime exposure to occupations and occupational exposures...
  14. doi request reprint Occupational asthma
    Joanna Szram
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College, London, United Kingdom
    Semin Respir Crit Care Med 33:653-65. 2012
    ..Occupational asthma is a disease that is potentially preventable and often curable; positive outcomes are dependent more on changes in the workplace than on pharmacological therapy...
  15. ncbi request reprint Asthma: environmental and occupational factors
    Paul Cullinan
    Department of Occupational and Environmental Lung Disease, Imperial College, London, UK
    Br Med Bull 68:227-42. 2003
    ..To date the 'hygiene hypothesis' offers the most efficient explanation for the distribution of the disease in time and place although convincing evidence for it remains elusive...
  16. doi request reprint Obliterative bronchiolitis in fibreglass workers: a new occupational disease?
    Paul Cullinan
    Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK
    Occup Environ Med 70:357-9. 2013
    ..Obliterative bronchiolitis (OB) is a rare disease with a small number of established occupational aetiologies. We describe a case series of severe OB in workers making glass-reinforced plastics...
  17. doi request reprint Growing old with cystic fibrosis - the characteristics of long-term survivors of cystic fibrosis
    Nicholas J Simmonds
    Department of Cystic Fibrosis, National Heart and Lung Institute, Imperial College and Royal Brompton Hospital, London, UK
    Respir Med 103:629-35. 2009
    ..We surveyed a population of long-term CF survivors to assess their burden of illness and profile their disease characteristics...
  18. ncbi request reprint Is occupational asthma to diisocyanates a non-IgE-mediated disease?
    Meinir G Jones
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Faculty of Medicine, Imperial College, London, UK
    J Allergy Clin Immunol 117:663-9. 2006
    ..There has been much debate as to whether this is due to diisocyanate-induced asthma being mediated by non-IgE mechanisms or whether it is the result of using inappropriate conjugates...
  19. ncbi request reprint Respiratory effects of exposure to diesel traffic in persons with asthma
    James McCreanor
    National Heart and Lung Institute, Imperial College, and Royal Brompton Hospital, London, United Kingdom
    N Engl J Med 357:2348-58. 2007
    ..We investigated the effects of short-term exposure to diesel traffic in people with asthma in an urban, roadside environment...
  20. ncbi request reprint HLA associations with occupational sensitization to rat lipocalin allergens: a model for other animal allergies?
    Hayley Jeal
    Department of Occupational and Environmental Medicine, Imperial College NHLI, London, United Kingdom
    J Allergy Clin Immunol 111:795-9. 2003
    ..Laboratory animal allergy is a common occupational health problem affecting between 11% and 44% of exposed researchers. Allergy to rats and mice is most common, probably because these are the animals most frequently used...
  21. ncbi request reprint Urban air pollution and children's asthma: what do parents and health professionals think?
    Emma Stevens
    Department of Environmental Science and Technology, Imperial College London, London, UK
    Pediatr Pulmonol 37:530-6. 2004
    ....
  22. doi request reprint Oral contraceptives do not appear to affect cystic fibrosis disease severity
    Natalie G Kernan
    Dept of Gene Therapy, Imperial College London, London, UK
    Eur Respir J 41:67-73. 2013
    ..Our data suggests that the use of OCs does not affect CF disease severity...
  23. ncbi request reprint Occupational asthma often goes unrecognised
    Paul Cullinan
    Royal Brompton Hospital, London, UK
    Practitioner 256:15-8, 2. 2012
    ..Patients should routinely be asked whether their symptoms improve when they are not at work...
  24. doi request reprint Medical surveillance for prevention of occupational asthma
    Joanna Szram
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK
    Curr Opin Allergy Clin Immunol 13:138-44. 2013
    ..Here we review one approach to prevention: the routine use of health surveillance in exposed workforces...
  25. pmc Occupational asthma: an assessment of diagnostic agreement between physicians
    David Fishwick
    Centre for Workplace Health, Health and Safety Laboratory, Harpur Hill, Buxton, Derbyshire SK17 9JN, UK
    Occup Environ Med 64:185-90. 2007
    ..To investigate the levels of agreement between expert respiratory physicians when making a diagnosis of occupational asthma...
  26. ncbi request reprint Domestic aeroallergen levels in Barcelona and Menorca (Spain)
    Xavier Basagana
    Respiratory and Environmental Health Research Unit, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
    Pediatr Allergy Immunol 13:412-7. 2002
    ..Additionally, allergen reduction measures related to indoor sources must be specific to each location...
  27. ncbi request reprint Bhopal priorities
    V Ramana Dhara
    Int J Occup Environ Health 10:107. 2004
  28. ncbi request reprint A prospective study of Fel d1 and Der p1 exposure in infancy and childhood wheezing
    Sarah Polk
    Unitat Recerca Respiratòria i Ambietal, Institut Municipal Investigacio Medica, Barcelona, Spain
    Am J Respir Crit Care Med 170:273-8. 2004
    ..77; 95% confidence interval = 1.19-6.46). Our data support the idea that several patterns of wheezing with different risk profiles exist among young children. The effect of Fel d1 exposure varied according to age and maternal asthma...
  29. ncbi request reprint Smoking cessation and associated factors during pregnancy
    Matias Torrent
    Area de Salut de Menorca ib salut, Spain
    Gac Sanit 18:184-9. 2004
    ..To examine smoking habits before and during pregnancy, as well as factors associated with smoking cessation, in three European settings...
  30. pmc Prenatal dichlorodiphenyldichloroethylene (DDE) and asthma in children
    Jordi Sunyer
    Unitat Recerca Respiratòria i Ambiental, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Environ Health Perspect 113:1787-90. 2005
    ..DDE was not associated with atopy alone. Prenatal exposure to DDE residues may contribute to development of asthma...
  31. ncbi request reprint Early-life domestic aeroallergen exposure and IgE sensitization at age 4 years
    Matias Torrent
    Menorca Health Area, Ib Salut, Menorca, Spain
    J Allergy Clin Immunol 118:742-8. 2006
    ....
  32. ncbi request reprint Peanuts in pregnancy: what is a mother to do?
    Seif O Shaheen
    Am J Respir Crit Care Med 178:113-4. 2008
  33. pmc Protective effect of fruits, vegetables and the Mediterranean diet on asthma and allergies among children in Crete
    Leda Chatzi
    Department of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece
    Thorax 62:677-83. 2007
    ..A study was undertaken to examine whether this discrepancy could be attributed to a high consumption of fresh fruit and vegetables or adherence to a traditional Mediterranean diet...
  34. ncbi request reprint Early-life allergen exposure and atopy, asthma, and wheeze up to 6 years of age
    Matias Torrent
    Menorca Health Area, ib salut Menorca, Institute Universitary d Investigacio en Ciencies de la Salut, Menorca, Spain
    Am J Respir Crit Care Med 176:446-53. 2007
    ....
  35. ncbi request reprint The incidence of cancer in patients with idiopathic pulmonary fibrosis and sarcoidosis in the UK
    Ivan Le Jeune
    Division of Epidemiology and Public Health, University of Nottingham, Clinical Sciences Building, Nottingham City Hospital, Nottingham NG5 1PB, UK
    Respir Med 101:2534-40. 2007
    ....
  36. pmc Personal exposure and long-term health effects in survivors of the union carbide disaster at bhopal
    V Ramana Dhara
    Emory Eastside Occupational Health Center, Snellville, Georgia, USA
    Environ Health Perspect 110:487-500. 2002
    ..04). The results show that total exposure weighted for distance has met the criteria for a successful index by being associated with most respiratory symptoms as well as FEF(25-75), features of obstructive airways disease...
  37. ncbi request reprint Seasonal allergic rhinitis is associated with a detrimental effect on examination performance in United Kingdom teenagers: case-control study
    Samantha Walker
    Education for Health, Warwick, United Kingdom
    J Allergy Clin Immunol 120:381-7. 2007
    ..Seasonal allergic rhinitis is common globally, and symptoms have been shown to impair learning ability in children in laboratory conditions. Critical examinations in children are often held in the summer during the peak grass pollen season...
  38. ncbi request reprint Chemical respiratory allergy: opportunities for hazard identification and characterisation. The report and recommendations of ECVAM workshop 60
    Ian Kimber
    Syngenta Central Toxicology Laboratory, Macclesfield, UK
    Altern Lab Anim 35:243-65. 2007