P Cullinan

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi request reprint The double macchiato years; awards for the best basic science and epidemiology papers in 2012
    Paul Cullinan
    Department of Occupational and Environmental Medicine, Imperial College NHLI, London, UK
    Thorax 68:777-9. 2013
  2. doi request reprint Obliterative bronchiolitis in fibreglass workers: a new occupational disease?
    Paul Cullinan
    Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK
    Occup Environ Med 70:357-9. 2013
  3. doi request reprint Occupation and chronic obstructive pulmonary disease (COPD)
    Paul Cullinan
    Occupational and Environmental Medicine, Imperial College NHLI, London, UK
    Br Med Bull 104:143-61. 2012
  4. ncbi request reprint Asthma: environmental and occupational factors
    Paul Cullinan
    Department of Occupational and Environmental Lung Disease, Imperial College, London, UK
    Br Med Bull 68:227-42. 2003
  5. ncbi request reprint Clinical aspects of occupational asthma
    P Cullinan
    Department of Occupational and Environmental, Medicine, Imperial College NHLI, London, UK
    Panminerva Med 46:111-20. 2004
  6. pmc Supermarket baker's asthma: how accurate is routine health surveillance?
    A Brant
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College, London, UK
    Occup Environ Med 62:395-9. 2005
  7. doi request reprint Dual sensitization to rat and mouse urinary allergens reflects cross-reactive molecules rather than atopy
    H Jeal
    Department of Occupational and Environmental Medicine, Imperial College, London, UK
    Allergy 64:855-61. 2009
  8. ncbi request reprint The prognosis of occupational asthma due to detergent enzymes: clinical, immunological and employment outcomes
    A Brant
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College, Royal Brompton Hospital, London, UK
    Clin Exp Allergy 36:483-8. 2006
  9. ncbi request reprint The changing distribution of occupational asthma: a survey of supermarket bakery workers
    A Brant
    Dept of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College, 1b Manresa Rd, London SW3 6LR, UK
    Eur Respir J 25:303-8. 2005
  10. ncbi request reprint Detergent protease exposure and respiratory disease: case-referent analysis of a retrospective cohort
    A Brant
    Department of Occupational and Environmental Medicine, Imperial College NHLI and Royal Brompton Hospital, London SW3 6LR, UK
    Occup Environ Med 66:754-8. 2009

Collaborators

Detail Information

Publications48

  1. doi request reprint The double macchiato years; awards for the best basic science and epidemiology papers in 2012
    Paul Cullinan
    Department of Occupational and Environmental Medicine, Imperial College NHLI, London, UK
    Thorax 68:777-9. 2013
    ..We think that comparisons are invidious but our chief editors, with all their schoolboy charm, disagree so here are our awards for the best basic science and epidemiological manuscripts in the year of the London Olympics. ..
  2. doi request reprint Obliterative bronchiolitis in fibreglass workers: a new occupational disease?
    Paul Cullinan
    Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK
    Occup Environ Med 70:357-9. 2013
    ..Obliterative bronchiolitis (OB) is a rare disease with a small number of established occupational aetiologies. We describe a case series of severe OB in workers making glass-reinforced plastics...
  3. doi request reprint Occupation and chronic obstructive pulmonary disease (COPD)
    Paul Cullinan
    Occupational and Environmental Medicine, Imperial College NHLI, London, UK
    Br Med Bull 104:143-61. 2012
    ..There is growing interest in preventable, non-smoking causes of chronic obstructive pulmonary disease (COPD), among which are chronic exposures to respiratory irritants in the workplace...
  4. ncbi request reprint Asthma: environmental and occupational factors
    Paul Cullinan
    Department of Occupational and Environmental Lung Disease, Imperial College, London, UK
    Br Med Bull 68:227-42. 2003
    ..To date the 'hygiene hypothesis' offers the most efficient explanation for the distribution of the disease in time and place although convincing evidence for it remains elusive...
  5. ncbi request reprint Clinical aspects of occupational asthma
    P Cullinan
    Department of Occupational and Environmental, Medicine, Imperial College NHLI, London, UK
    Panminerva Med 46:111-20. 2004
    ..Management is more difficult since there are often important employment and other social issues to be taken into account...
  6. pmc Supermarket baker's asthma: how accurate is routine health surveillance?
    A Brant
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College, London, UK
    Occup Environ Med 62:395-9. 2005
    ..Regular health surveillance is commonly recommended for workers exposed to occupational antigens but little is known about how effective it is in identifying cases...
  7. doi request reprint Dual sensitization to rat and mouse urinary allergens reflects cross-reactive molecules rather than atopy
    H Jeal
    Department of Occupational and Environmental Medicine, Imperial College, London, UK
    Allergy 64:855-61. 2009
    ..We examined cross-reactivity between rat and mouse urine and the effect atopy has on dual sensitization in laboratory animal workers...
  8. ncbi request reprint The prognosis of occupational asthma due to detergent enzymes: clinical, immunological and employment outcomes
    A Brant
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College, Royal Brompton Hospital, London, UK
    Clin Exp Allergy 36:483-8. 2006
    ..Little is known about the prognosis of occupational asthma induced by high molecular weight proteins...
  9. ncbi request reprint The changing distribution of occupational asthma: a survey of supermarket bakery workers
    A Brant
    Dept of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College, 1b Manresa Rd, London SW3 6LR, UK
    Eur Respir J 25:303-8. 2005
    ..Changes in the location and process of bread manufacture have led to a change in the distribution of bakers' asthma in the UK...
  10. ncbi request reprint Detergent protease exposure and respiratory disease: case-referent analysis of a retrospective cohort
    A Brant
    Department of Occupational and Environmental Medicine, Imperial College NHLI and Royal Brompton Hospital, London SW3 6LR, UK
    Occup Environ Med 66:754-8. 2009
    ..To examine the relationship between protease exposure and respiratory disease in a cohort of detergent enzyme manufacturers...
  11. ncbi request reprint Determination of the T cell epitopes of the lipocalin allergen, Rat n 1
    H Jeal
    Department of Occupational and Environmental Medicine, Imperial College, London SW3 6LR, UK
    Clin Exp Allergy 34:1919-25. 2004
    ..To date, Bos d 2 is the only mammalian lipocalin allergen to have been studied in detail...
  12. doi request reprint Temporal changes in UK birth order and the prevalence of atopy
    S Upchurch
    Occupational and Environmental Medicine, Imperial College School of Medicine NHLI, London, UK
    Allergy 65:1039-41. 2010
    ..Many studies have reported an inverse association between birth order and the risk of respiratory allergic disease. In recent decades, the prevalence of atopy has increased alongside reductions in fertility rates...
  13. ncbi request reprint Environmental associations with eczema in early life
    J M Harris
    Department of Occupational and Environmental Medicine, Imperial College of Science and Technology National Heart and Lung Institute, 1B Manresa Road, London SW3 6LR, UK
    Br J Dermatol 144:795-802. 2001
    ..Although atopic eczema (AE) is a common disease, little is known about its causes...
  14. pmc Early allergen exposure, skin prick responses, and atopic wheeze at age 5 in English children: a cohort study
    P Cullinan
    Department of Occupational and Environmental Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, Manresa Road, London SW3 6LR, UK
    Thorax 59:855-61. 2004
    ..There are, however, few prospective data in support. We aimed to examine this relationship in a representative cohort of children born in Ashford, Kent (UK)...
  15. ncbi request reprint The effects of farming and birth order on asthma and allergies
    C Zekveld
    Dept of Occupational and Environmental, Imperial College of School of Medicine National Heart and Lung Institute, London, UK
    Eur Respir J 28:82-8. 2006
    ..Thus farming effects may be specific to local practices. First-born children in this community also appear to be at increased risk of allergic disease...
  16. ncbi request reprint Allergen and dust exposure as determinants of work-related symptoms and sensitization in a cohort of flour-exposed workers; a case-control analysis
    P Cullinan
    Department of Occupational and Environmental Medicine, Imperial College, NHLI, SW3 6LR, London, UK
    Ann Occup Hyg 45:97-103. 2001
    ..To estimate the incidence of specific IgE sensitization and allergic respiratory symptoms among UK bakery and flour mill workers; and to examine the roles of flour aeroallergen and total dust exposures in determining these outcomes...
  17. ncbi request reprint Early allergen exposure and atopic eczema
    J M Harris
    Occupational and Environmental Medicine, Imperial College School of Medicine, 1B Manresa Road, London SW3 6LR, UK
    Br J Dermatol 156:698-704. 2007
    ....
  18. ncbi request reprint Crete: does farming explain urban and rural differences in atopy?
    M Barnes
    Department of Occupational and Environmental Medicine, Imperial College School of Medicine NHLI and Royal Brompton and Harefield Hospital, London, UK
    Clin Exp Allergy 31:1822-8. 2001
    ..Within Europe, where such variations are less striking, a farm childhood has been postulated to be protective...
  19. doi request reprint Occupational egg allergy in an embryological research facility
    M Jones
    Department of Occupational and Environmental Medicine, Imperial College, London, UK
    Occup Med (Lond) 63:348-53. 2013
    ..Two newly identified cases prompted us to examine the extent of this problem in a university laboratory...
  20. pmc Estimating the incidence of occupational asthma and rhinitis from laboratory animal allergens in the UK, 1999-2000
    A Draper
    Department of Occupational and Environmental Medicine, Royal Brompton Hospital and NHLI, London, UK
    Occup Environ Med 60:604-5. 2003
    ..56/1000 employees. Although reported cases are rare, estimated incidence rates of asthma attributable to birds (23.9/1000/year) and insects (2.35/1000/year) are high...
  21. ncbi request reprint Interaction of HLA phenotype and exposure intensity in sensitization to complex platinum salts
    A J Newman Taylor
    Department of Occupational and Environmental Medicine, Imperial College School of Medicine National Heart and Lung Institute, London, United Kingdom
    Am J Respir Crit Care Med 160:435-8. 1999
    ..They imply that as exposure-control measures are taken to prevent occupational sensitization and, by analogy, sensitization to allergens outside the workplace, disease incidence will increasingly be determined by genetic susceptibility...
  22. ncbi request reprint Childhood peak flow and the Oxford Transport Strategy
    S J MacNeill
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, 16 Manresa Road, London, UK
    Thorax 64:651-6. 2009
    ..The impact of the OTS on peak expiratory flow (PEF) and respiratory symptoms among schoolchildren in the city is reported...
  23. doi request reprint Cryptogenic fibrosing alveolitis and lung cancer: the BTS study
    J M Harris
    Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College, 1B Manresa Road, London SW3 6LR, UK
    Thorax 65:70-6. 2010
    ..The risk of lung cancer is often reported to be increased for patients with cryptogenic fibrosing alveolitis (CFA)...
  24. pmc The introduction of solids in relation to asthma and eczema
    A Zutavern
    Dr von Haunersches Kinderspital University Children s Hospital, Department of Occupational and Environmental Medicine, Imperial College of Science and Technology, National Heart and Lung Institute, London, UK
    Arch Dis Child 89:303-8. 2004
    ..Despite scarce scientific evidence, current feeding guidelines recommend delayed introduction of solids for the prevention of asthma and allergy...
  25. ncbi request reprint New pregnancies and loss of allergy
    J M Harris
    Department of Occupational and Environmental Medicine, Imperial College NHLI, London, UK
    Clin Exp Allergy 34:369-72. 2004
    ..Alternative explanations include the possibility that pregnancy itself determines maternal atopic status...
  26. ncbi request reprint Asthma and allergies: is the farming environment (still) protective in Poland? The GABRIEL Advanced Studies
    S J MacNeill
    Department of Occupational and Environmental Medicine, National Heart and Lung Istitute, Imperial College London, London, UK
    Allergy 68:771-9. 2013
    ....
  27. ncbi request reprint Association of maternal anti-HLA class II antibodies with protection from allergy in offspring
    M Jones
    Department of Occupational and Environmental Medicine, Imperial College, London, UK
    Allergy 68:1143-9. 2013
    ..In this study, we investigated whether production of HLA antibodies 4 years after pregnancy with index child is associated with allergic outcomes in offspring at 8 years...
  28. ncbi request reprint Can early infection explain the sibling effect in adult atopy?
    P Cullinan
    Dept of Occupational and Environmental Medicine, Imperial College School of Medicine NHLI, London, UK
    Eur Respir J 22:956-61. 2003
    ..The findings support the suggestion that the "sibling effect" in atopy may not simply reflect protection by early infection...
  29. pmc Early prescriptions of antibiotics and the risk of allergic disease in adults: a cohort study
    P Cullinan
    Department of Occupational and Environmental Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, UK
    Thorax 59:11-5. 2004
    ..It is frequently asserted that antibiotic prescriptions in childhood are associated with the development of allergic disease, especially asthma. A study was undertaken to establish the direction of this relationship...
  30. doi request reprint Cystic fibrosis and survival to 40 years: a case-control study
    N J Simmonds
    Dept of Cystic Fibrosis, Royal Brompton Hospital, Sydney Street, London, UK
    Eur Respir J 36:1277-83. 2010
    ..Even "early-diagnosis" disease appears to have different phenotypes, possibly independent of CF gene function, that have different survival patterns...
  31. ncbi request reprint Occupational distribution and geographic clustering of deaths certified to be cryptogenic fibrosing alveolitis in england and wales
    J M Harris
    Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College, London, UK
    Chest 119:428-33. 2001
    ....
  32. pmc Occupational asthma caused by cellulase and lipase in the detergent industry
    A Brant
    Department of Occupational and Environmental Medicine, Royal Brompton Hospital, Imperial College NHLI, 1b Manresa Rd, London SW36LR, UK
    Occup Environ Med 61:793-5. 2004
    ..Four of the most common enzymes used in this industry have now been reported to cause occupational asthma; continued vigilance and caution are needed when working with these or other enzymes...
  33. ncbi request reprint The prevention of occupational asthma
    P Cullinan
    Dept of Occupational and Environmental Medicine, Imperial College NHLI, London, UK
    Eur Respir J 22:853-60. 2003
    ..Considerably more cooperation between scientists in the field, regulatory authorities and industry is required...
  34. doi request reprint Respiratory protective equipment reduces occurrence of sensitization to laboratory animals
    M Jones
    Department of Occupational and Environmental Medicine, Imperial College, London SW3 6LR, UK
    Occup Med (Lond) 64:104-8. 2014
    ..Respiratory protective equipment (RPE) has been shown to reduce exposure to laboratory animal allergens, but there are no studies that have examined its effect on the development of sensitization...
  35. ncbi request reprint Latex allergy. A position paper of the British Society of Allergy and Clinical Immunology
    P Cullinan
    Imperial College, London, UK
    Clin Exp Allergy 33:1484-99. 2003
  36. pmc Occupational asthma from fungicides fluazinam and chlorothalonil
    A Draper
    Department of Occupational and Environmental Medicine, Royal Brompton Hospital and NHLI, 1B Manresa Road, London SW3 6LR, UK
    Occup Environ Med 60:76-7. 2003
    ..These fungicides are known to cause dermatitis; this report indicates that these compounds can induce specific immunological reactions in the airways as well as skin...
  37. ncbi request reprint Long term morbidity in survivors of the 1984 Bhopal gas leak
    P Cullinan
    National Heart and Lung Institute, London, UK
    Natl Med J India 9:5-10. 1996
    ..In 1994 an International Medical Commission was set up with the aim of assessing respiratory, neurological and other health effects attributable to gas exposure...
  38. ncbi request reprint BSACI guidelines for the management of allergic and non-allergic rhinitis
    G K Scadding
    The Royal National Throat Nose and Ear Hospital, Gray s Inn Road, London, UK
    Clin Exp Allergy 38:19-42. 2008
    ..There are also special sections for children, co-morbid associations and pregnancy. Finally, we have made recommendations for potential areas of future research...
  39. ncbi request reprint Amiodarone-associated thyroid dysfunction: risk factors in adults with congenital heart disease
    S A Thorne
    Grown Up Congenital Heart Disease Unit, Royal Brompton Hospital, Department of Occupational and Environmental Medicine, Imperial College of Science, Technology, and Medicine, London, UK
    Circulation 100:149-54. 1999
    ..A retrospective study was performed to examine the frequency of amiodarone-associated thyroid dysfunction in adults with congenital heart disease and to identify any contributing factors...
  40. pmc Exposure-response relations among laboratory animal workers exposed to rats
    M J Nieuwenhuijsen
    Department of Environmental Science and Technology, Imperial College of Science, Technology and Medicine, Royal School of Mines, London SW7 2BP, UK
    Occup Environ Med 60:104-8. 2003
    ..To explore exposure-response relations in a cohort of laboratory animal workers...
  41. ncbi request reprint Childhood atopy and allergic disease and skin test responses to environmental mycobacteria in rural Crete: a cross-sectional survey
    I Bibakis
    Anti Tuberculosis Unit, Venizalion Hospital, Heraklion, Crete
    Clin Exp Allergy 35:624-9. 2005
    ..Through its powerful immunoregulatory effects, infection with atypical mycobacteria may exert a protective effect on the development of childhood allergic disease...
  42. pmc Evidence based guidelines for the prevention, identification, and management of occupational asthma
    P J Nicholson
    Procter and Gamble, Whitehall Lane, Egham, Surrey, UK
    Occup Environ Med 62:290-9. 2005
    ..This work was commissioned by the British Occupational Health Research Foundation to assist the Health and Safety Executive in achieving its target of reducing the incidence of occupational asthma in Great Britain by 30% by 2010...
  43. ncbi request reprint Atopy and asthma in rural Poland: a paradigm for the emergence of childhood respiratory allergies in Europe
    B Sozanska
    Department of Paediatrics, Allergology and Cardiology, Wroclaw Medical University, Wroclaw, Poland
    Allergy 62:394-400. 2007
    ..We hypothesized that, in south-west Poland, a 'rural' protective effect on atopy and respiratory allergies would be most pronounced among children but that at all ages would be stronger among those with a rural background...
  44. pmc Childhood allergies, birth order and family size
    P Cullinan
    Thorax 61:3-5. 2006
  45. ncbi request reprint Interstitial lung diseases: an epidemiological overview
    M Demedts
    Pulmonary Division, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Belgium
    Eur Respir J Suppl 32:2s-16s. 2001
    ..Notwithstanding the aforementioned problems, this report tries to provide a balanced overview of the epidemiology of different interstitial lung diseases...
  46. pmc BOHRF guidelines for occupational asthma
    A J Newman Taylor
    Thorax 60:364-6. 2005
  47. ncbi request reprint Standards of care for occupational asthma
    D Fishwick
    Centre for Workplace Health, Respiratory Function Unit, A Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
    Thorax 63:240-50. 2008
  48. ncbi request reprint Concentrations and determinants of NO2 in homes of Ashford, UK and Barcelona and Menorca, Spain
    O Garcia Algar
    Pediatrics Service, Hospital del Mar, Barcelona, Spain
    Indoor Air 14:298-304. 2004
    ..In conclusion, despite differences in indoor NO2 mean concentrations probably reflecting different outdoor NO2 level, home factors affecting indoor NO2 values and their specific contributions were constant across the three cohorts...