D J Crockford

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi request reprint Curve-fitting method for direct quantitation of compounds in complex biological mixtures using 1H NMR: application in metabonomic toxicology studies
    D J Crockford
    Biological Chemistry, Biomedical Sciences Division, Faculty of Medicine, Imperial College London, SW7 2AZ, UK
    Anal Chem 77:4556-62. 2005
  2. ncbi request reprint Statistical search space reduction and two-dimensional data display approaches for UPLC-MS in biomarker discovery and pathway analysis
    Derek J Crockford
    Biological Chemistry, Division of Biomedical Sciences, Sir Alexander Fleming Building, Imperial College, London, SW7 2AZ, UK
    Anal Chem 78:4398-408. 2006
  3. doi request reprint 1H NMR and UPLC-MS(E) statistical heterospectroscopy: characterization of drug metabolites (xenometabolome) in epidemiological studies
    Derek J Crockford
    Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Medicine and Anaesthetics, Sir Alexander Fleming Building, Imperial College London, UK
    Anal Chem 80:6835-44. 2008
  4. ncbi request reprint Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies
    Derek J Crockford
    Biological Chemistry, Division of Biomedical Sciences, Sir Alexander Fleming Building, Imperial College London, SW7 2AZ, UK
    Anal Chem 78:363-71. 2006

Detail Information

Publications4

  1. ncbi request reprint Curve-fitting method for direct quantitation of compounds in complex biological mixtures using 1H NMR: application in metabonomic toxicology studies
    D J Crockford
    Biological Chemistry, Biomedical Sciences Division, Faculty of Medicine, Imperial College London, SW7 2AZ, UK
    Anal Chem 77:4556-62. 2005
    ..The results of all these tests give confidence that the technique can be used in automated quantitation of compounds in large NMR data sets with minimal operator intervention...
  2. ncbi request reprint Statistical search space reduction and two-dimensional data display approaches for UPLC-MS in biomarker discovery and pathway analysis
    Derek J Crockford
    Biological Chemistry, Division of Biomedical Sciences, Sir Alexander Fleming Building, Imperial College, London, SW7 2AZ, UK
    Anal Chem 78:4398-408. 2006
    ....
  3. doi request reprint 1H NMR and UPLC-MS(E) statistical heterospectroscopy: characterization of drug metabolites (xenometabolome) in epidemiological studies
    Derek J Crockford
    Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Medicine and Anaesthetics, Sir Alexander Fleming Building, Imperial College London, UK
    Anal Chem 80:6835-44. 2008
    ..This approach is of great potential value in the description of population xenometabolomes and in population pharmacology studies, and indeed for drug metabolism studies in general...
  4. ncbi request reprint Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies
    Derek J Crockford
    Biological Chemistry, Division of Biomedical Sciences, Sir Alexander Fleming Building, Imperial College London, SW7 2AZ, UK
    Anal Chem 78:363-71. 2006
    ..Biological applications of SHY as demonstrated here show promise as a new systems biology tool for biomarker recovery...