Frances M Cowan
Affiliation: Imperial College
- The internal capsule in neonatal imagingFrances M Cowan
Department of Paediatrics, Imperial College, Hammersmith Hospital, London, UK
Semin Fetal Neonatal Med 10:461-74. 2005..Future studies will assess the relevance of these findings not only for motor outcome but also for cognitive, visual and sensory abilities...
- Pilot randomized trial of therapeutic hypothermia with serial cranial ultrasound and 18-22 month follow-up for neonatal encephalopathy in a low resource hospital setting in Uganda: study protocolNicola J Robertson
Institute for Women s Health, 86 96 Chenies Mews, University College London, London, UK
Trials 12:138. 2011..However, the greatest burden of perinatal asphyxia falls in low and mid-resource settings where it is unclear whether therapeutic hypothermia is safe and effective...
- Neonatal ECMO Study of Temperature (NEST)--a randomised controlled trialDavid J Field
Department of Heath Science, Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester, UK
BMC Pediatr 10:24. 2010..Infants allocated to the control group will receive ECMO at 37 degrees C throughout their course, which is currently standard practice around the world. Health status of both groups will be assessed formally at 2 years corrected age...
- Does cranial ultrasound imaging identify arterial cerebral infarction in term neonates?F Cowan
Department of Paediatrics and Neonatal Medicine, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
Arch Dis Child Fetal Neonatal Ed 90:F252-6. 2005..To evaluate the diagnostic accuracy of cranial ultrasound (CUS) for detection of neonatal arterial territory cerebral infarction in term infants...
- Origin and timing of brain lesions in term infants with neonatal encephalopathyFrances Cowan
Department of Paediatrics, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK
Lancet 361:736-42. 2003..However, there is no evidence that brain damage occurs before birth. We aimed to test the hypothesis that neonatal encephalopathy, early neonatal seizures, or both result from early antenatal insults...
- Specific relations between neurodevelopmental abilities and white matter microstructure in children born pretermSerena J Counsell
Imaging Sciences Department, Robert Steiner MR Unit, Imperial College London, Hammersmith Hospital, London, UK
Brain 131:3201-8. 2008..FA may aid prognostication and provide a biomarker for therapeutic or mechanistic studies of preterm brain injury...
- Natural history of brain lesions in extremely preterm infants studied with serial magnetic resonance imaging from birth and neurodevelopmental assessmentLeigh E Dyet
Department of Paediatrics, Medical Research Council Clinical Sciences Centre, Imperial College, Hammersmith Campus, London, United Kingdom
Pediatrics 118:536-48. 2006....
- White matter and cortical injury in hypoxic-ischemic encephalopathy: antecedent factors and 2-year outcomeMiriam Martinez-Biarge
Department of Pediatrics and Imaging Sciences, Imperial College, Hammersmith Hospital Campus, London, United Kingdom
J Pediatr 161:799-807. 2012..To examine the spectrum of isolated white matter (WM)/cortical injury and its relation to outcomes in infants with hypoxic-ischemic encephalopathy (HIE) and normal appearing basal ganglia and thalami...
- Prediction of neurodevelopmental outcome after hypoxic-ischemic encephalopathy treated with hypothermia by diffusion tensor imaging analyzed using tract-based spatial statisticsNora Tusor
Centre for the Developing Brain, Imperial College and MRC Clinical Sciences Centre, Hammersmith Hospital, London, UK
Pediatr Res 72:63-9. 2012....
- Thalamo-cortical connectivity in children born preterm mapped using probabilistic magnetic resonance tractographySerena J Counsell
Robert Steiner MR Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, DuCane Road, London, W12 0HS, UK
Neuroimage 34:896-904. 2007..This technique promises to be a useful tool for assessing connectivity in the developing brain and in infants with lesions...
- Patterns of cerebral injury and neurodevelopmental outcomes after symptomatic neonatal hypoglycemiaCharlotte M Burns
Department of Paediatrics, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, England
Pediatrics 122:65-74. 2008..Brain injury patterns identified on early MRI scans and their relationships to the nature of the hypoglycemic insult and neurodevelopmental outcomes are poorly defined...
- Structural linear measurements in the newborn brain: accuracy of cranial ultrasound compared to MRILara M Leijser
Department of Paediatrics, Hammersmith Hospital, Imperial College, Du Cane Road, London W12 OHS, UK
Pediatr Radiol 37:640-8. 2007..Cranial ultrasonography (cUS) is the primary method used for evaluating the neonatal brain and it is important to know whether linear measurements made using this technique are accurate...
- Patterns of brain injury in neonates exposed to perinatal sentinel eventsAkudo Okereafor
Department of Paediatrics and Neonatal Medicine, Hammersmith Hospital, Du Cane Rd, London, W12 OHS, United Kingdom
Pediatrics 121:906-14. 2008....
- Frequently encountered cranial ultrasound features in the white matter of preterm infants: correlation with MRILara M Leijser
Department of Paediatrics, Imaging Science Department, Clinical Sciences Centre, Hammersmith Hospital, Imperial College, London, UK
Eur J Paediatr Neurol 13:317-26. 2009..Bilateral symmetrical echogenic and echolucent areas in the white matter are frequently seen on the cranial ultrasound scans of apparently well preterm infants without overt pathology...
- Tractography of the corticospinal tracts in infants with focal perinatal injury: comparison with normal controls and to motor developmentElise Roze
Centre for the Developing Brain, Imperial College, Hammersmith Campus, London, UK
Neuroradiology 54:507-16. 2012....
- The effect of preterm birth on neonatal cerebral vasculature studied with magnetic resonance angiography at 3 TeslaChristina Malamateniou
Robert Steiner MRI Unit, Imaging Sciences Department, Hammersmith Hospital Campus, Imperial College London, London, UK
Neuroimage 32:1050-9. 2006....
- Outcomes after central grey matter injury in term perinatal hypoxic-ischaemic encephalopathyMiriam Martinez-Biarge
Department of Paediatrics and Imaging Sciences, Imperial College London, UK
Early Hum Dev 86:675-82. 2010..We present a guide for predicting outcome at 2 years in different developmental domains based on the severity of injury seen in the basal ganglia and thalami (BGT) on neonatal MRI...
- A common neonatal image phenotype predicts adverse neurodevelopmental outcome in children born pretermJ P Boardman
Institute of Clinical Sciences, Imperial College London and MRC Clinical Sciences Centre, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
Neuroimage 52:409-14. 2010....
- MR imaging quantification of cerebellar growth following hypoxic-ischemic injury to the neonatal brainElisabeth Le Strange
Robert Steiner Magnetic Resonance Unit, Imaging Sciences Department, Imperial College, Hammersmith Campus, Du Cane Road, London W12 0HS, England, UK
AJNR Am J Neuroradiol 25:463-8. 2004..We sought to determine whether perinatal hypoxic-ischemic injury leads to poor cerebellar growth and whether such impairment occurs asymmetrically in infants with predominantly unilateral brain injury...
- Neurological examination of preterm infants at term equivalent ageDaniela Ricci
Department of Paediatrics and Imaging Sciences, Hammersmith Campus, Imperial College, London, UK
Early Hum Dev 84:751-61. 2008..However, the cohort number was too small to draw any definitive conclusion about the distribution of findings...
- T2 relaxation values in the developing preterm brainSerena J Counsell
Robert Steiner MR Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Campus, Imperial College, DuCane Road, London, England
AJNR Am J Neuroradiol 24:1654-60. 2003..The aim of this study was to obtain T2 values in the preterm brain from 25 weeks' gestational age (GA) until term-equivalent age in infants who had normal neurodevelopmental findings at a minimum corrected age of 1 year...
- How you ask really matters: randomised comparison of four sexual behaviour questionnaire delivery modes in Zimbabwean youthLisa F Langhaug
University College London, London, UK
Sex Transm Infect 87:165-73. 2011..A sexual health survey among rural Zimbabwean youth was used to compare the validity and reliability of sexual behaviour measures between four questionnaire delivery modes...
- Using cerebral ultrasound effectively in the newborn infantLara M Leijser
Department of Paediatrics and Imaging Science Department, Imperial College, Hammersmith Hospital, Du Cane Road, London, UK
Early Hum Dev 82:827-35. 2006..Issues of concern regarding teaching, supervision and experience of the examiner are also addressed...
- Diffusion-weighted imaging of the brain in preterm infants with focal and diffuse white matter abnormalitySerena J Counsell
Robert Steiner Magnetic Resonance Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Campus, London, United Kingdom
Pediatrics 112:1-7. 2003....
- School based HIV prevention in Zimbabwe: feasibility and acceptability of evaluation trials using biological outcomesFrances M Cowan
Department of Sexually Transmitted Diseases, Royal Free and University College Medical School, London, UK
AIDS 16:1673-8. 2002..To determine the feasibility and acceptability of conducting a community randomized trial (CRT) of an adolescent reproductive health intervention (ARHI) using biological measures of effectiveness...
- Predicting motor outcome and death in term hypoxic-ischemic encephalopathyM Martinez-Biarge
Department of Pediatrics, Hammersmith Hospital, London, UK
Neurology 76:2055-61. 2011....
- Prothrombotic disorders and abnormal neurodevelopmental outcome in infants with neonatal cerebral infarctionE Mercuri
Departments of Paediatrics, Imperial College, Hammersmith Campus, London, United Kingdom
Pediatrics 107:1400-4. 2001....
- Neurological and perceptual-motor outcome at 5 - 6 years of age in children with neonatal encephalopathy: relationship with neonatal brain MRIA Barnett
Department of Paediatrics, Imperial College School of Medicine, Hammersmith Campus, London, United Kingdom
Neuropediatrics 33:242-8. 2002....
- Comparison of findings on cranial ultrasound and magnetic resonance imaging in preterm infantsE F Maalouf
Department of Paediatrics, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
Pediatrics 107:719-27. 2001..In addition, normal WM echogenicity on US is not a good predictor of normal WM signal intensity on MRI...
- Maturation of cerebral electrical activity and development of cortical folding in young very preterm infantsE Biagioni
Department of Paediatrics, Imperial College Hammersmith Hospital, London, UK
Clin Neurophysiol 118:53-9. 2007..The aim of this study was to examine the relationship between cortical development and cerebral electrical activity at early gestational ages...
- Neonatal cerebral infarction and visual function at school ageE Mercuri
Department of Paediatrics, Hammersmith Campus, Imperial College School of Medicine, London, UK
Arch Dis Child Fetal Neonatal Ed 88:F487-91. 2003..To assess various aspects of visual function at school age in children with neonatal cerebral infarction...
- Probabilistic diffusion tractography of the optic radiations and visual function in preterm infants at term equivalent ageLaura Bassi
NICU, Institute of Pediatrics and Neonatology, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, University of Milan, Italy
Brain 131:573-82. 2008..Our results suggest that in preterm infants at term equivalent age visual function is directly related to the development of white matter in the optic radiations...
- Axial and radial diffusivity in preterm infants who have diffuse white matter changes on magnetic resonance imaging at term-equivalent ageSerena J Counsell
Imaging Sciences Department, MRC Clinical Sciences Centre, London, United Kingdom
Pediatrics 117:376-86. 2006....
- Should cranial MRI screening of preterm infants become routine?Linda S de Vries
Department of Neonatology, Wilhelmina Children s Hospital, Utrecht, The Netherlands
Nat Clin Pract Neurol 3:532-3. 2007
- The value of autopsy in determining the cause of failure to respond to resuscitation at birthWaney Squier
Department of Neuropathology, Radcliffe Infirmary, Oxford OX2 6HE, UK
Semin Neonatol 9:331-45. 2004..Metabolic disease, including peroxisomal disorders, non-ketotic hyperglycinaemia, lipid and glycogen storage disorders and mitochondrial diseases may cause profound hypotonia and respiratory failure at birth or shortly afterwards...