Frances M Cowan

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi The internal capsule in neonatal imaging
    Frances M Cowan
    Department of Paediatrics, Imperial College, Hammersmith Hospital, London, UK
    Semin Fetal Neonatal Med 10:461-74. 2005
  2. doi Antepartum and intrapartum factors preceding neonatal hypoxic-ischemic encephalopathy
    Miriam Martinez-Biarge
    MRCPCH, Department of Paediatrics, 5 Floor, Hammersmith House, Hammersmith Hospital, DuCane Rd, London W12 OHS, United Kingdom
    Pediatrics 132:e952-9. 2013
  3. pmc Pilot randomized trial of therapeutic hypothermia with serial cranial ultrasound and 18-22 month follow-up for neonatal encephalopathy in a low resource hospital setting in Uganda: study protocol
    Nicola J Robertson
    Institute for Women s Health, 86 96 Chenies Mews, University College London, London, UK
    Trials 12:138. 2011
  4. pmc Neonatal ECMO Study of Temperature (NEST)--a randomised controlled trial
    David J Field
    Department of Heath Science, Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester, UK
    BMC Pediatr 10:24. 2010
  5. pmc Does cranial ultrasound imaging identify arterial cerebral infarction in term neonates?
    F Cowan
    Department of Paediatrics and Neonatal Medicine, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
    Arch Dis Child Fetal Neonatal Ed 90:F252-6. 2005
  6. ncbi Origin and timing of brain lesions in term infants with neonatal encephalopathy
    Frances Cowan
    Department of Paediatrics, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK
    Lancet 361:736-42. 2003
  7. doi Specific relations between neurodevelopmental abilities and white matter microstructure in children born preterm
    Serena J Counsell
    Imaging Sciences Department, Robert Steiner MR Unit, Imperial College London, Hammersmith Hospital, London, UK
    Brain 131:3201-8. 2008
  8. doi White matter and cortical injury in hypoxic-ischemic encephalopathy: antecedent factors and 2-year outcome
    Miriam Martinez-Biarge
    Department of Pediatrics and Imaging Sciences, Imperial College, Hammersmith Hospital Campus, London, United Kingdom
    J Pediatr 161:799-807. 2012
  9. ncbi Thalamo-cortical connectivity in children born preterm mapped using probabilistic magnetic resonance tractography
    Serena J Counsell
    Robert Steiner MR Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, DuCane Road, London, W12 0HS, UK
    Neuroimage 34:896-904. 2007
  10. doi Prediction of neurodevelopmental outcome after hypoxic-ischemic encephalopathy treated with hypothermia by diffusion tensor imaging analyzed using tract-based spatial statistics
    Nora Tusor
    Centre for the Developing Brain, Imperial College and MRC Clinical Sciences Centre, Hammersmith Hospital, London, UK
    Pediatr Res 72:63-9. 2012

Collaborators

Detail Information

Publications42

  1. ncbi The internal capsule in neonatal imaging
    Frances M Cowan
    Department of Paediatrics, Imperial College, Hammersmith Hospital, London, UK
    Semin Fetal Neonatal Med 10:461-74. 2005
    ..Future studies will assess the relevance of these findings not only for motor outcome but also for cognitive, visual and sensory abilities...
  2. doi Antepartum and intrapartum factors preceding neonatal hypoxic-ischemic encephalopathy
    Miriam Martinez-Biarge
    MRCPCH, Department of Paediatrics, 5 Floor, Hammersmith House, Hammersmith Hospital, DuCane Rd, London W12 OHS, United Kingdom
    Pediatrics 132:e952-9. 2013
    ..To determine whether antepartum factors alone, intrapartum factors alone, or both in combination, are associated with term neonatal hypoxic-ischemic encephalopathy (HIE)...
  3. pmc Pilot randomized trial of therapeutic hypothermia with serial cranial ultrasound and 18-22 month follow-up for neonatal encephalopathy in a low resource hospital setting in Uganda: study protocol
    Nicola J Robertson
    Institute for Women s Health, 86 96 Chenies Mews, University College London, London, UK
    Trials 12:138. 2011
    ..However, the greatest burden of perinatal asphyxia falls in low and mid-resource settings where it is unclear whether therapeutic hypothermia is safe and effective...
  4. pmc Neonatal ECMO Study of Temperature (NEST)--a randomised controlled trial
    David J Field
    Department of Heath Science, Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester, UK
    BMC Pediatr 10:24. 2010
    ..Infants allocated to the control group will receive ECMO at 37 degrees C throughout their course, which is currently standard practice around the world. Health status of both groups will be assessed formally at 2 years corrected age...
  5. pmc Does cranial ultrasound imaging identify arterial cerebral infarction in term neonates?
    F Cowan
    Department of Paediatrics and Neonatal Medicine, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
    Arch Dis Child Fetal Neonatal Ed 90:F252-6. 2005
    ..To evaluate the diagnostic accuracy of cranial ultrasound (CUS) for detection of neonatal arterial territory cerebral infarction in term infants...
  6. ncbi Origin and timing of brain lesions in term infants with neonatal encephalopathy
    Frances Cowan
    Department of Paediatrics, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK
    Lancet 361:736-42. 2003
    ..However, there is no evidence that brain damage occurs before birth. We aimed to test the hypothesis that neonatal encephalopathy, early neonatal seizures, or both result from early antenatal insults...
  7. doi Specific relations between neurodevelopmental abilities and white matter microstructure in children born preterm
    Serena J Counsell
    Imaging Sciences Department, Robert Steiner MR Unit, Imperial College London, Hammersmith Hospital, London, UK
    Brain 131:3201-8. 2008
    ..FA may aid prognostication and provide a biomarker for therapeutic or mechanistic studies of preterm brain injury...
  8. doi White matter and cortical injury in hypoxic-ischemic encephalopathy: antecedent factors and 2-year outcome
    Miriam Martinez-Biarge
    Department of Pediatrics and Imaging Sciences, Imperial College, Hammersmith Hospital Campus, London, United Kingdom
    J Pediatr 161:799-807. 2012
    ..To examine the spectrum of isolated white matter (WM)/cortical injury and its relation to outcomes in infants with hypoxic-ischemic encephalopathy (HIE) and normal appearing basal ganglia and thalami...
  9. ncbi Thalamo-cortical connectivity in children born preterm mapped using probabilistic magnetic resonance tractography
    Serena J Counsell
    Robert Steiner MR Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, DuCane Road, London, W12 0HS, UK
    Neuroimage 34:896-904. 2007
    ..This technique promises to be a useful tool for assessing connectivity in the developing brain and in infants with lesions...
  10. doi Prediction of neurodevelopmental outcome after hypoxic-ischemic encephalopathy treated with hypothermia by diffusion tensor imaging analyzed using tract-based spatial statistics
    Nora Tusor
    Centre for the Developing Brain, Imperial College and MRC Clinical Sciences Centre, Hammersmith Hospital, London, UK
    Pediatr Res 72:63-9. 2012
    ....
  11. doi Feeding and communication impairments in infants with central grey matter lesions following perinatal hypoxic-ischaemic injury
    Miriam Martinez-Biarge
    Department of Paediatrics and Imaging Sciences, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom
    Eur J Paediatr Neurol 16:688-96. 2012
    ..However there is no equivalent predictive data for other specific outcomes. Feeding and communication impairments are also common in children following hypoxic-ischaemic encephalopathy (HIE) and BGT injury...
  12. doi Patterns of brain injury in neonates exposed to perinatal sentinel events
    Akudo Okereafor
    Department of Paediatrics and Neonatal Medicine, Hammersmith Hospital, Du Cane Rd, London, W12 OHS, United Kingdom
    Pediatrics 121:906-14. 2008
    ....
  13. ncbi Natural history of brain lesions in extremely preterm infants studied with serial magnetic resonance imaging from birth and neurodevelopmental assessment
    Leigh E Dyet
    Department of Paediatrics, Medical Research Council Clinical Sciences Centre, Imperial College, Hammersmith Campus, London, United Kingdom
    Pediatrics 118:536-48. 2006
    ....
  14. ncbi Axial and radial diffusivity in preterm infants who have diffuse white matter changes on magnetic resonance imaging at term-equivalent age
    Serena J Counsell
    Imaging Sciences Department, MRC Clinical Sciences Centre, London, United Kingdom
    Pediatrics 117:376-86. 2006
    ....
  15. doi Patterns of cerebral injury and neurodevelopmental outcomes after symptomatic neonatal hypoglycemia
    Charlotte M Burns
    Department of Paediatrics, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, England
    Pediatrics 122:65-74. 2008
    ..Brain injury patterns identified on early MRI scans and their relationships to the nature of the hypoglycemic insult and neurodevelopmental outcomes are poorly defined...
  16. ncbi Structural linear measurements in the newborn brain: accuracy of cranial ultrasound compared to MRI
    Lara M Leijser
    Department of Paediatrics, Hammersmith Hospital, Imperial College, Du Cane Road, London W12 OHS, UK
    Pediatr Radiol 37:640-8. 2007
    ..Cranial ultrasonography (cUS) is the primary method used for evaluating the neonatal brain and it is important to know whether linear measurements made using this technique are accurate...
  17. ncbi The effect of preterm birth on neonatal cerebral vasculature studied with magnetic resonance angiography at 3 Tesla
    Christina Malamateniou
    Robert Steiner MRI Unit, Imaging Sciences Department, Hammersmith Hospital Campus, Imperial College London, London, UK
    Neuroimage 32:1050-9. 2006
    ....
  18. doi Frequently encountered cranial ultrasound features in the white matter of preterm infants: correlation with MRI
    Lara M Leijser
    Department of Paediatrics, Imaging Science Department, Clinical Sciences Centre, Hammersmith Hospital, Imperial College, London, UK
    Eur J Paediatr Neurol 13:317-26. 2009
    ..Bilateral symmetrical echogenic and echolucent areas in the white matter are frequently seen on the cranial ultrasound scans of apparently well preterm infants without overt pathology...
  19. ncbi Development of the optic radiations and visual function after premature birth
    Michela Groppo
    Centre for the Developing Brain, Imperial College, London, United Kingdom NICU, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Universita degli Studi di Milano, Milano, Italy
    Cortex 56:30-7. 2014
    ..We tested the hypothesis that these abnormalities develop during the late preterm period...
  20. doi Neurodevelopmental outcome in children with congenital heart disease
    Miriam Martinez-Biarge
    Department of Paediatrics, Hammersmith Hospital, Imperial College, London, UK
    Semin Fetal Neonatal Med 18:279-85. 2013
    ..Long-term neurodevelopmental follow-up of children with CHD is warranted for early identification of and intervention for difficulties. ..
  21. pmc 'How poor are you?' -- a comparison of four questionnaire delivery modes for assessing socio-economic position in rural zimbabwe
    Sophie J S Pascoe
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 8:e74977. 2013
    ..This paper reports on results of a trial of four QDMs, and the effect of mode on poverty reporting...
  22. doi Tractography of the corticospinal tracts in infants with focal perinatal injury: comparison with normal controls and to motor development
    Elise Roze
    Centre for the Developing Brain, Imperial College, Hammersmith Campus, London, UK
    Neuroradiology 54:507-16. 2012
    ....
  23. doi Outcomes after central grey matter injury in term perinatal hypoxic-ischaemic encephalopathy
    Miriam Martinez-Biarge
    Department of Paediatrics and Imaging Sciences, Imperial College London, UK
    Early Hum Dev 86:675-82. 2010
    ..We present a guide for predicting outcome at 2 years in different developmental domains based on the severity of injury seen in the basal ganglia and thalami (BGT) on neonatal MRI...
  24. ncbi A common neonatal image phenotype predicts adverse neurodevelopmental outcome in children born preterm
    J P Boardman
    Institute of Clinical Sciences, Imperial College London and MRC Clinical Sciences Centre, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
    Neuroimage 52:409-14. 2010
    ....
  25. doi How you ask really matters: randomised comparison of four sexual behaviour questionnaire delivery modes in Zimbabwean youth
    Lisa F Langhaug
    University College London, London, UK
    Sex Transm Infect 87:165-73. 2011
    ..A sexual health survey among rural Zimbabwean youth was used to compare the validity and reliability of sexual behaviour measures between four questionnaire delivery modes...
  26. ncbi MR imaging quantification of cerebellar growth following hypoxic-ischemic injury to the neonatal brain
    Elisabeth Le Strange
    Robert Steiner Magnetic Resonance Unit, Imaging Sciences Department, Imperial College, Hammersmith Campus, Du Cane Road, London W12 0HS, England, UK
    AJNR Am J Neuroradiol 25:463-8. 2004
    ..We sought to determine whether perinatal hypoxic-ischemic injury leads to poor cerebellar growth and whether such impairment occurs asymmetrically in infants with predominantly unilateral brain injury...
  27. doi Neurological examination of preterm infants at term equivalent age
    Daniela Ricci
    Department of Paediatrics and Imaging Sciences, Hammersmith Campus, Imperial College, London, UK
    Early Hum Dev 84:751-61. 2008
    ..However, the cohort number was too small to draw any definitive conclusion about the distribution of findings...
  28. pmc Difference in prevalence of common mental disorder as measured using four questionnaire delivery methods among young people in rural Zimbabwe
    Lisa F Langhaug
    Royal Free and University College Medical School, London, United Kingdom
    J Affect Disord 118:220-3. 2009
    ..We report here on differences in prevalence of reporting mental health between four questionnaire delivery modes (QDM)...
  29. doi Evaluation of early childhood social-communication difficulties in children born preterm using the Quantitative Checklist for Autism in Toddlers
    Hilary S Wong
    Section of Neonatal Medicine, Department of Medicine, Chelsea and Westminster Hospital, Imperial College London, London, United Kingdom
    J Pediatr 164:26-33.e1. 2014
    ....
  30. ncbi Using cerebral ultrasound effectively in the newborn infant
    Lara M Leijser
    Department of Paediatrics and Imaging Science Department, Imperial College, Hammersmith Hospital, Du Cane Road, London, UK
    Early Hum Dev 82:827-35. 2006
    ..Issues of concern regarding teaching, supervision and experience of the examiner are also addressed...
  31. ncbi T2 relaxation values in the developing preterm brain
    Serena J Counsell
    Robert Steiner MR Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Campus, Imperial College, DuCane Road, London, England
    AJNR Am J Neuroradiol 24:1654-60. 2003
    ..The aim of this study was to obtain T2 values in the preterm brain from 25 weeks' gestational age (GA) until term-equivalent age in infants who had normal neurodevelopmental findings at a minimum corrected age of 1 year...
  32. ncbi Diffusion-weighted imaging of the brain in preterm infants with focal and diffuse white matter abnormality
    Serena J Counsell
    Robert Steiner Magnetic Resonance Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Campus, London, United Kingdom
    Pediatrics 112:1-7. 2003
    ....
  33. ncbi School based HIV prevention in Zimbabwe: feasibility and acceptability of evaluation trials using biological outcomes
    Frances M Cowan
    Department of Sexually Transmitted Diseases, Royal Free and University College Medical School, London, UK
    AIDS 16:1673-8. 2002
    ..To determine the feasibility and acceptability of conducting a community randomized trial (CRT) of an adolescent reproductive health intervention (ARHI) using biological measures of effectiveness...
  34. pmc Predicting motor outcome and death in term hypoxic-ischemic encephalopathy
    M Martinez-Biarge
    Department of Pediatrics, Hammersmith Hospital, London, UK
    Neurology 76:2055-61. 2011
    ....
  35. ncbi Maturation of cerebral electrical activity and development of cortical folding in young very preterm infants
    E Biagioni
    Department of Paediatrics, Imperial College Hammersmith Hospital, London, UK
    Clin Neurophysiol 118:53-9. 2007
    ..The aim of this study was to examine the relationship between cortical development and cerebral electrical activity at early gestational ages...
  36. ncbi Neurological and perceptual-motor outcome at 5 - 6 years of age in children with neonatal encephalopathy: relationship with neonatal brain MRI
    A Barnett
    Department of Paediatrics, Imperial College School of Medicine, Hammersmith Campus, London, United Kingdom
    Neuropediatrics 33:242-8. 2002
    ....
  37. pmc Neonatal cerebral infarction and visual function at school age
    E Mercuri
    Department of Paediatrics, Hammersmith Campus, Imperial College School of Medicine, London, UK
    Arch Dis Child Fetal Neonatal Ed 88:F487-91. 2003
    ..To assess various aspects of visual function at school age in children with neonatal cerebral infarction...
  38. ncbi Prothrombotic disorders and abnormal neurodevelopmental outcome in infants with neonatal cerebral infarction
    E Mercuri
    Departments of Paediatrics, Imperial College, Hammersmith Campus, London, United Kingdom
    Pediatrics 107:1400-4. 2001
    ....
  39. ncbi Comparison of findings on cranial ultrasound and magnetic resonance imaging in preterm infants
    E F Maalouf
    Department of Paediatrics, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
    Pediatrics 107:719-27. 2001
    ..In addition, normal WM echogenicity on US is not a good predictor of normal WM signal intensity on MRI...
  40. doi Probabilistic diffusion tractography of the optic radiations and visual function in preterm infants at term equivalent age
    Laura Bassi
    NICU, Institute of Pediatrics and Neonatology, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, University of Milan, Italy
    Brain 131:573-82. 2008
    ..Our results suggest that in preterm infants at term equivalent age visual function is directly related to the development of white matter in the optic radiations...
  41. ncbi Should cranial MRI screening of preterm infants become routine?
    Linda S de Vries
    Department of Neonatology, Wilhelmina Children s Hospital, Utrecht, The Netherlands
    Nat Clin Pract Neurol 3:532-3. 2007
  42. ncbi The value of autopsy in determining the cause of failure to respond to resuscitation at birth
    Waney Squier
    Department of Neuropathology, Radcliffe Infirmary, Oxford OX2 6HE, UK
    Semin Neonatol 9:331-45. 2004
    ..Metabolic disease, including peroxisomal disorders, non-ketotic hyperglycinaemia, lipid and glycogen storage disorders and mitochondrial diseases may cause profound hypotonia and respiratory failure at birth or shortly afterwards...