Research Topics
| Naomi J CloutSummaryAffiliation: Imperial College Country: UK Publications
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Detail Information
Publications
A model of FAS1 domain 4 of the corneal protein beta(ig)-h3 gives a clearer view on corneal dystrophiesNaomi J Clout
Department of Biological Sciences, Imperial College London, South Kensington Campus, London, United Kingdom
Mol Vis 9:440-8. 2003..The integrin binding properties of beta(ig)-h3, described in several recent studies, have been analysed with respect to the beta(ig)-h3 structure...
Binding site for Robo receptors revealed by dissection of the leucine-rich repeat region of SlitJason A Howitt
Department of Biological Sciences, Imperial College London, London, UK
EMBO J 23:4406-12. 2004..Our results show that a small portion of Slit is able to induce Robo signalling and indicate that the distinct functions of Drosophila Robos are encoded in their divergent cytosolic domains...
Novel fold revealed by the structure of a FAS1 domain pair from the insect cell adhesion molecule fasciclin INaomi J Clout
Biophysics Section, Department of Biological Sciences, Imperial College, SW7 2AZ, London, United Kingdom
Structure 11:197-203. 2003..Many mutations alter highly conserved core residues, but the two most common mutations, affecting Arg-124 and Arg-555, map to exposed alpha-helical regions, suggesting reduced protein solubility as the disease mechanism...
Crystal structure of the LG1-3 region of the laminin alpha2 chainFederico Carafoli
Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom
J Biol Chem 284:22786-92. 2009..The alpha 2LG1-3 structure provides the first atomic view of the integrin binding region of laminins...
Structural basis for Gas6-Axl signallingTakako Sasaki
Max Planck Institut fur Biochemie, Martinsried, Germany
EMBO J 25:80-7. 2006..Specificity at the major contact is suggested to result from the segregation of charged and apolar residues to opposite faces of the newly formed beta-sheet...
