P R Clarke

Summary

Affiliation: Imperial Cancer Research Fund
Country: UK

Publications

  1. ncbi request reprint Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle?
    P R Clarke
    Biomedical Research Centre, Level 5, Ninewells Hospital and Medical School, University of Dundee, DD1 9SY, Dundee, UK
    Trends Cell Biol 11:366-71. 2001
  2. ncbi request reprint Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts
    C Zhang
    Biomedical Research Centre, University of Dundee, Level 5, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK
    Science 288:1429-32. 2000
  3. ncbi request reprint Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system
    C Zhang
    Biomedical Research Centre, Level 5, Ninewells Hospital and Medical School, University of Dundee, DD1 9SY, Scotland, UK
    Curr Biol 11:208-12. 2001
  4. ncbi request reprint XMog1, a nuclear ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe mog1p that co-operates with RanBP1 to control generation of Ran-GTP
    F J Nicolas
    Biomedical Research Centre, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
    J Cell Sci 114:3013-23. 2001

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle?
    P R Clarke
    Biomedical Research Centre, Level 5, Ninewells Hospital and Medical School, University of Dundee, DD1 9SY, Dundee, UK
    Trends Cell Biol 11:366-71. 2001
    ..Here, we review these advances and discuss a general model for Ran in the coordination of nuclear processes throughout the cell division cycle via common biochemical mechanisms...
  2. ncbi request reprint Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts
    C Zhang
    Biomedical Research Centre, University of Dundee, Level 5, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK
    Science 288:1429-32. 2000
    ..Thus, concentration of Ran-GDP followed by generation of Ran-GTP is sufficient to induce NE assembly...
  3. ncbi request reprint Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system
    C Zhang
    Biomedical Research Centre, Level 5, Ninewells Hospital and Medical School, University of Dundee, DD1 9SY, Scotland, UK
    Curr Biol 11:208-12. 2001
    ..Thus, the GTP-GDP cycle of Ran controls both the recruitment of vesicles and their fusion to form NEs...
  4. ncbi request reprint XMog1, a nuclear ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe mog1p that co-operates with RanBP1 to control generation of Ran-GTP
    F J Nicolas
    Biomedical Research Centre, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
    J Cell Sci 114:3013-23. 2001
    ..We propose that Mog1-related proteins, together with RanBP1, facilitate the generation of Ran-GTP from Ran-GDP in the nucleus...