P R Clarke
Affiliation: Imperial Cancer Research Fund
- Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle?P R Clarke
Biomedical Research Centre, Level 5, Ninewells Hospital and Medical School, University of Dundee, DD1 9SY, Dundee, UK
Trends Cell Biol 11:366-71. 2001..Here, we review these advances and discuss a general model for Ran in the coordination of nuclear processes throughout the cell division cycle via common biochemical mechanisms...
- Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extractsC Zhang
Biomedical Research Centre, University of Dundee, Level 5, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK
Science 288:1429-32. 2000..Thus, concentration of Ran-GDP followed by generation of Ran-GTP is sufficient to induce NE assembly...
- Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free systemC Zhang
Biomedical Research Centre, Level 5, Ninewells Hospital and Medical School, University of Dundee, DD1 9SY, Scotland, UK
Curr Biol 11:208-12. 2001..Thus, the GTP-GDP cycle of Ran controls both the recruitment of vesicles and their fusion to form NEs...
- XMog1, a nuclear ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe mog1p that co-operates with RanBP1 to control generation of Ran-GTPF J Nicolas
Biomedical Research Centre, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
J Cell Sci 114:3013-23. 2001..We propose that Mog1-related proteins, together with RanBP1, facilitate the generation of Ran-GTP from Ran-GDP in the nucleus...