Research Topics
| Moises A CalderonSummaryAffiliation: Imperial College Country: UK Publications
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Detail Information
Publications
EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapyMoises A Calderon
Section of Allergy and Clinical Immunology, Imperial College, National Heart and Lung Institute, Dovehouse Street, London, SW3 6LY, UK
Clin Transl Allergy 2:20. 2012....
Perspectives on allergen-specific immunotherapy in childhood: an EAACI position statementM A Calderon
Department of Allergy and Respiratory Medicine, Royal Brompton Hospital, Imperial College, London, UK
Pediatr Allergy Immunol 23:300-6. 2012..Working together for the benefit of the community is essential. The European Academy of Allergy and Clinical Immunology (EAACI) serves as the platform of such cooperation...
Comparability of subcutaneous and sublingual immunotherapy outcomes in allergic rhinitis clinical trialsMoises A Calderon
Section of Allergy and Clinical Immunology, Imperial College, National Heart and Lung Institute, Royal Brompton Hospital, London, UK
Curr Opin Allergy Clin Immunol 12:249-56. 2012..To conduct a qualitative comparison between the primary and secondary outcomes used in clinical trials of subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) for allergic rhinitis...
Multiple-allergen and single-allergen immunotherapy strategies in polysensitized patients: looking at the published evidenceMoises A Calderon
Imperial College National Heart and Lung Institute, Royal Brompton Hospital, London, UK
J Allergy Clin Immunol 129:929-34. 2012..Sublingual and subcutaneous multiallergen immunotherapy in polysensitized patients requires more supporting data to validate its efficacy in practice...
One hundred years of allergen immunotherapy European Academy of Allergy and Clinical Immunology celebration: review of unanswered questionsM Calderon
Imperial College London, National Heart and Lung Institute, London, UK
Allergy 67:462-76. 2012..On the centenary of Noon's discovery, European experts in the field of immunotherapy met in Geneva under the aegis of the EAACI to discuss these controversial issues. This study presents outcomes and conclusions from these discussions...
Sublingual allergen immunotherapy: mode of action and its relationship with the safety profileM A Calderon
Section of Allergy and Clinical Immunology, Imperial College NHLI, Royal Brompton Hospital, London, UK
Allergy 67:302-11. 2012..Anaphylaxis risk factors associated with SCIT and/or SLIT should be characterized further...
Sublingual immunotherapy for allergic conjunctivitis: Cochrane systematic review and meta-analysisM A Calderon
Section of Allergy and Clinical Immunology, Imperial College NHLI, Royal Brompton Hospital, London, UK
Clin Exp Allergy 41:1263-72. 2011..Sublingual immunotherapy (SLIT) is an effective and safe treatment for nasal symptoms of AR; its effectiveness is however less well established for ocular symptoms...
European Academy of Allergy and Clinical Immunology task force report on 'dose-response relationship in allergen-specific immunotherapy'M A Calderon
National Heart and Lung Institute, Imperial College London, UK
Allergy 66:1345-59. 2011..Allergen products for SIT are being increasingly required to conform to regulatory requirements for human medicines, which include the need to demonstrate dose-dependent effects...
Immunotherapy: The meta-analyses. What have we Learned?Moises A Calderon
Department of Allergy and Respiratory Medicine, Imperial College, National Heart and Lung Institute, Royal Brompton and Harefield Trust, Dovehouse Street, London SW3 6LY, UK
Immunol Allergy Clin North Am 31:159-73, vii. 2011..The safety profile of SIT should be evaluated using international guidelines and terminology, and needs to include high-quality surveillance data...
Allergen-specific immunotherapy for respiratory allergies: from meta-analysis to registration and beyondMoises A Calderon
Section of Allergy and Clinical Immunology, Imperial College, NHLI, Royal Brompton Hospital, London, United Kingdom
J Allergy Clin Immunol 127:30-8. 2011..In this review, the authors put into perspective current international expert recommendations on the use of SIT (in relation to levels of clinical evidence) and analyze what is needed for the future...
Specific immunotherapy with high dose SO standardized grass allergen tablets was safe and well toleratedM Calderon
Upper Respiratory Medicine, Royal Brompton Hospital, Imperial College, London, United Kingdom
J Investig Allergol Clin Immunol 16:338-44. 2006..Rhinoconjunctivitis and asthma co-exist and we aimed to find a safe dose range of a self-administered grass allergen tablet (ALK Abello A/S) in patients suffering from rhinoconjunctivitis and asthma...
Grass pollen immunotherapy: IL-10 induction and suppression of late responses precedes IgG4 inhibitory antibody activityJames N Francis
Allergy and Clinical Immunology Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom
J Allergy Clin Immunol 121:1120-1125.e2. 2008..Grass pollen immunotherapy is an effective treatment for seasonal allergic rhinitis that provides the opportunity to study the induction and maintenance of allergen-specific immune tolerance...
Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomesGuy W Scadding
Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, UK
J Immunol Methods 384:25-32. 2012..Our model allows correlation between clinical responses and local biomarkers following nasal allergen challenge...
Sublingual immunotherapy for treating allergic conjunctivitisMoises A Calderon
Department of Allergy and Respiratory Medicine, Royal Brompton Hospital, Imperial College School of Medicine at the National Heart and Lung Institute, London, UK, SW3 6LY
Cochrane Database Syst Rev 7:CD007685. 2011..Sublingual Immunotherapy (SLIT) is an effective and well-tolerated treatment for allergic rhinitis, but its effects on symptoms of ocular allergy have not been well established...
Adjuvants for immunotherapyOliver Pfaar
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Mannheim, Germany
Curr Opin Allergy Clin Immunol 12:648-57. 2012..This article gives an overview about the current state of preclinical and clinical studies using different kinds of adjuvants and their effect on allergen-specific immunotherapy (SIT)...
