Research Topics
| Sarah BurlSummaryAffiliation: Imperial College Country: UK Publications
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Detail Information
Publications
Age-dependent maturation of Toll-like receptor-mediated cytokine responses in Gambian infantsSarah Burl
Infant Immunology, Medical Research Council UK The Gambia, Fajara, The Gambia
PLoS ONE 6:e18185. 2011..These observations provide fresh insights into the ontogeny of innate immunity in African children, and may inform development of age-specific adjuvanted vaccine formulations important for global health...
Delaying bacillus Calmette-Guérin vaccination from birth to 4 1/2 months of age reduces postvaccination Th1 and IL-17 responses but leads to comparable mycobacterial responses at 9 months of ageSarah Burl
Medical Research Council United Kingdom, The Gambia, Fajara, The Gambia, West Africa
J Immunol 185:2620-8. 2010..The evidence did not suggest that mycobacterial specific naturally occurring Tregs accounted for this attenuated immunogenicity...
The tuberculin skin test (TST) is affected by recent BCG vaccination but not by exposure to non-tuberculosis mycobacteria (NTM) during early lifeSarah Burl
Infant Immunology, Medical Research Council UK The Gambia, Fajara, The Gambia
PLoS ONE 5:e12287. 2010..Collectively these data provide further insights into how the TST is regulated in early life, and how a positive response might be interpreted...
The challenge of assessing infant vaccine responses in resource-poor settingsKatie L Flanagan
Medical Research Council UK The Gambia, Fajara, The Gambia
Expert Rev Vaccines 9:665-74. 2010..In this article, we will review immunity to vaccines in early life, discuss the many challenges associated with assessing immunogenicity and provide practical tips...
The effect of placental malaria infection on cord blood and maternal immunoregulatory responses at birthKatie L Flanagan
MRC Laboratories, Fajara, The Gambia
Eur J Immunol 40:1062-72. 2010..The findings might explain some of the adverse effects on the health of babies born to women with PM...
