R Boyton

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. pmc Immune mechanisms and the impact of the disrupted lung microbiome in chronic bacterial lung infection and bronchiectasis
    R J Boyton
    Lung Immunology Group, Section of Infectious Diseases and Immunity, Hammersmith Campus, Department of Medicine, Centre for Respiratory Infection, Imperial College London, UK
    Clin Exp Immunol 171:117-23. 2013
  2. doi request reprint Immune regulation in idiopathic bronchiectasis
    Rosemary J Boyton
    Department of Medicine, Section of Infectious Diseases and Immunity, Lung Immunology Group and Human Disease Immunogenetics Group, Imperial College, London, United Kingdom
    Ann N Y Acad Sci 1272:68-72. 2012
  3. pmc Innate immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1)
    Pascal F Durrenberger
    Department of Medicine, Section of Infectious Diseases and Immunity, Commonwealth Building, Hammersmith Campus, Imperial College London, UK
    J Neuroinflammation 9:1. 2012
  4. doi request reprint Regulation of immunity in bronchiectasis
    R J Boyton
    Imperial College London, National Heart and Lung Institute, London, UK
    Med Mycol 47:S175-82. 2009
  5. pmc Human leucocyte antigen class II association in idiopathic bronchiectasis, a disease of chronic lung infection, implicates a role for adaptive immunity
    R J Boyton
    Lung Immunology Group, NHLI, Sir Alexander Fleming Building, South Kensington Campus, Faculty of Medicine, Imperial College, London, UK
    Clin Exp Immunol 152:95-101. 2008
  6. ncbi request reprint The role of natural killer T cells in lung inflammation
    R Boyton
    Lung Immunology Group, National Heart and Lung Institute, Imperial College London, UK
    J Pathol 214:276-82. 2008
  7. pmc Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease
    R J Boyton
    Lung Immunology Group, National Heart and Lung Institute, Sir Alexander Fleming Building, South Kensington Campus, Faculty of Medicine, Imperial College, London, UK
    Clin Exp Immunol 149:1-8. 2007
  8. ncbi request reprint IFN gamma and CXCR-1 gene polymorphisms in idiopathic bronchiectasis
    R J Boyton
    Lung Immunology Group, Infection and Immunity and National Heart and Lung Institute, Sir Alexander Fleming Building, South Kensington Campus, Faculty of Medicine, Imperial College, London SW7 2AZ, UK
    Tissue Antigens 68:325-30. 2006
  9. ncbi request reprint HLA-C and killer cell immunoglobulin-like receptor genes in idiopathic bronchiectasis
    Rosemary J Boyton
    Lung Immunology Group, Department of Biological Sciences National Heart and Lung Institute, Sir Alexander Fleming Building, South Kensington Campus, London SW7 2AZ, UK
    Am J Respir Crit Care Med 173:327-33. 2006
  10. ncbi request reprint Pulmonary infection with Cryptococcus neoformans in the face of underlying sarcoidosis
    Rosemary J Boyton
    Lung Immunology Group, Department of Biological Sciences NHLI, Faculty of Medicine, Imperial College London, London, UK
    Respiration 74:462-6. 2007

Collaborators

Detail Information

Publications14

  1. pmc Immune mechanisms and the impact of the disrupted lung microbiome in chronic bacterial lung infection and bronchiectasis
    R J Boyton
    Lung Immunology Group, Section of Infectious Diseases and Immunity, Hammersmith Campus, Department of Medicine, Centre for Respiratory Infection, Imperial College London, UK
    Clin Exp Immunol 171:117-23. 2013
    ..This review discusses the implication of these concepts for the development of therapeutic interventions...
  2. doi request reprint Immune regulation in idiopathic bronchiectasis
    Rosemary J Boyton
    Department of Medicine, Section of Infectious Diseases and Immunity, Lung Immunology Group and Human Disease Immunogenetics Group, Imperial College, London, United Kingdom
    Ann N Y Acad Sci 1272:68-72. 2012
    ..Recent evidence indicates a possible role of excessive natural killer cell activation in pathogenesis...
  3. pmc Innate immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1)
    Pascal F Durrenberger
    Department of Medicine, Section of Infectious Diseases and Immunity, Commonwealth Building, Hammersmith Campus, Imperial College London, UK
    J Neuroinflammation 9:1. 2012
    ..In this study, we investigated whether there were differences in NCR1+ cells in the peripheral blood of MS patients and whether NCR1+ cells are present in white matter lesions...
  4. doi request reprint Regulation of immunity in bronchiectasis
    R J Boyton
    Imperial College London, National Heart and Lung Institute, London, UK
    Med Mycol 47:S175-82. 2009
    ..A role for adaptive immune mechanisms is suggested by the genetic association of HLA-DR1, DQ5 with increased susceptibility to idiopathic bronchiectasis...
  5. pmc Human leucocyte antigen class II association in idiopathic bronchiectasis, a disease of chronic lung infection, implicates a role for adaptive immunity
    R J Boyton
    Lung Immunology Group, NHLI, Sir Alexander Fleming Building, South Kensington Campus, Faculty of Medicine, Imperial College, London, UK
    Clin Exp Immunol 152:95-101. 2008
    ..This may operate either through influencing susceptibility to specific pathogens or to self-reactivity and requires further investigation...
  6. ncbi request reprint The role of natural killer T cells in lung inflammation
    R Boyton
    Lung Immunology Group, National Heart and Lung Institute, Imperial College London, UK
    J Pathol 214:276-82. 2008
    ....
  7. pmc Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease
    R J Boyton
    Lung Immunology Group, National Heart and Lung Institute, Sir Alexander Fleming Building, South Kensington Campus, Faculty of Medicine, Imperial College, London, UK
    Clin Exp Immunol 149:1-8. 2007
    ....
  8. ncbi request reprint IFN gamma and CXCR-1 gene polymorphisms in idiopathic bronchiectasis
    R J Boyton
    Lung Immunology Group, Infection and Immunity and National Heart and Lung Institute, Sir Alexander Fleming Building, South Kensington Campus, Faculty of Medicine, Imperial College, London SW7 2AZ, UK
    Tissue Antigens 68:325-30. 2006
    ..These polymorphisms were distributed similarly in the idiopathic bronchiectasis group and controls, suggesting that these two candidate gene polymorphisms are not associated with disease susceptibility...
  9. ncbi request reprint HLA-C and killer cell immunoglobulin-like receptor genes in idiopathic bronchiectasis
    Rosemary J Boyton
    Lung Immunology Group, Department of Biological Sciences National Heart and Lung Institute, Sir Alexander Fleming Building, South Kensington Campus, London SW7 2AZ, UK
    Am J Respir Crit Care Med 173:327-33. 2006
    ..A possible role for natural killer (NK) cells is suggested by the observation that familial bronchiectasis occurs in a rare group of individuals with impaired HLA class I expression and consequent NK cell dysfunction...
  10. ncbi request reprint Pulmonary infection with Cryptococcus neoformans in the face of underlying sarcoidosis
    Rosemary J Boyton
    Lung Immunology Group, Department of Biological Sciences NHLI, Faculty of Medicine, Imperial College London, London, UK
    Respiration 74:462-6. 2007
    ..Novel immunotherapeutic options for cryptococcal infection are discussed...
  11. ncbi request reprint Infectious lung complications in patients with HIV/AIDS
    Rosemary J Boyton
    Lung Immunology Group, Department of Biological Sciences and National Heart and Lung Institute, Sir Alexander Fleming Building, South Kensington Campus, Imperial College, London, UK
    Curr Opin Pulm Med 11:203-7. 2005
    ....
  12. pmc Reciprocal conditioning: T cells as regulators of dendritic cell function
    Daniel M Altmann
    Human Disease Immunogenetics Group, Department of Infectious Diseases, Imperial College London, Hammersmith Hospital, London, UK
    Immunology 109:473-5. 2003
  13. ncbi request reprint Is selection for TCR affinity a factor in cytokine polarization?
    Rosemary J Boyton
    Human Disease Immunogenetics Group, Dept of Infectious Diseases, Hammersmith Hospital, Du Cane Road, London, UK W12 ONN
    Trends Immunol 23:526-9. 2002
    ..Reliance on experiments using a single, transgenic TCR polarized into either subset might have obscured the fact that, under physiological conditions, there is selection for differential TCRs on the basis of affinity...
  14. ncbi request reprint Pulmonary defences to acute respiratory infection
    Rosemary J Boyton
    National Heart and Lung Institute at St Mary s Hospital, Imperial College School of Medicine, London, UK
    Br Med Bull 61:1-12. 2002
    ..Different populations of T lymphocytes may dramatically alter the balance between clearance of the pathogen and induction of tissue damage depending on the cytokines they secrete...