- Bowels control brain: gut hormones and obesityGavin A Bewick
Section of Investigative Medicine, Imperial College London, London, United Kingdom
Biochem Med (Zagreb) 22:283-97. 2012..This review gives an overview of the main gut hormones implicated in the regulation of food intake and how some of these are being targeted to develop anti obesity treatments...
- The hyperphagic effect of ghrelin is inhibited in mice by a diet high in fatJames V Gardiner
Department of Investigative Medicine, Hammersmith Campus, Imperial College London, London, UK
Gastroenterology 138:2468-76, 2476.e1. 2010..These mice, as expected, are hyperphagic and glucose intolerant. We investigated whether exposure to a high-fat diet (HFD) would exacerbate this phenotype...
- The role of the gut/brain axis in modulating food intakeAmir H Sam
Section of Investigative Medicine, Imperial College London, London W12 0NN, UK
Neuropharmacology 63:46-56. 2012..Research in this area has provided novel targets for the pharmacological treatment of obesity. This article is part of a Special Issue entitled 'Central Control Food Intake'..
- Prokineticin 2 is a hypothalamic neuropeptide that potently inhibits food intakeJames V Gardiner
Department of Investigative Medicine, Imperial College London, London, UK
Diabetes 59:397-406. 2010..Prokineticin 2 (PK2) is a hypothalamic neuropeptide expressed in central nervous system areas known to be involved in food intake. We therefore hypothesized that PK2 plays a role in energy homeostasis...