Puspa Batten

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi request reprint Human mesenchymal stem cells induce T cell anergy and downregulate T cell allo-responses via the TH2 pathway: relevance to tissue engineering human heart valves
    Puspa Batten
    Heart Science Centre, National Heart and Lung Institute, Imperial College London at Harefield Hospital, Harefield, Middlesex, United Kingdom
    Tissue Eng 12:2263-73. 2006
  2. pmc Immune response to stem cells and strategies to induce tolerance
    Puspa Batten
    Tissue Engineering Group, Heart Science Centre, National Heart and Lung Institute, Imperial College London, Harefield Hospital, Harefield, Middlesex UB9 6JH, UK
    Philos Trans R Soc Lond B Biol Sci 362:1343-56. 2007
  3. ncbi request reprint Characterization of structural and signaling molecules by human valve interstitial cells and comparison to human mesenchymal stem cells
    Najma Latif
    Imperial College, National Heart and Lung Institute, Heart Science Centre, Harefield Hospital, Harefield, Middlesex UB9 6JH, UK
    J Heart Valve Dis 16:56-66. 2007
  4. ncbi request reprint Collagen synthesis by mesenchymal stem cells and aortic valve interstitial cells in response to mechanical stretch
    Ching Hsin Ku
    Department of Cardiothoracic Surgery, Heart Science Centre, Harefield Hospital, NHLI, Imperial College London, UK
    Cardiovasc Res 71:548-56. 2006
  5. ncbi request reprint Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells seeded on collagen scaffolds-relevance to tissue engineering
    John V Terrovitis
    Heart Science Centre, Harefield Hospital, Imperial College, London, United Kingdom
    Tissue Eng 12:2765-75. 2006
  6. ncbi request reprint The cardiac valve interstitial cell
    Patricia M Taylor
    Division of Cardiothoracic Surgery, National Heart and Lung Institute, Faculty of Medicine, Imperial College of Science, Technology and Medicine at Harefield Hospital, Heart Science Centre, Middlesex, Harefield, UB9 6JH, UK
    Int J Biochem Cell Biol 35:113-8. 2003
  7. ncbi request reprint Loss of ecto-5'nucleotidase from porcine endothelial cells after exposure to human blood: Implications for xenotransplantation
    Zain Khalpey
    Heart Science Centre, Imperial College at Harefield Hospital, Middlesex UB9 6JH, UK
    Biochim Biophys Acta 1741:191-8. 2005

Detail Information

Publications7

  1. ncbi request reprint Human mesenchymal stem cells induce T cell anergy and downregulate T cell allo-responses via the TH2 pathway: relevance to tissue engineering human heart valves
    Puspa Batten
    Heart Science Centre, National Heart and Lung Institute, Imperial College London at Harefield Hospital, Harefield, Middlesex, United Kingdom
    Tissue Eng 12:2263-73. 2006
    ..This implies that allogeneic MSCs could be a suitable cell source for tissue engineering a heart valve...
  2. pmc Immune response to stem cells and strategies to induce tolerance
    Puspa Batten
    Tissue Engineering Group, Heart Science Centre, National Heart and Lung Institute, Imperial College London, Harefield Hospital, Harefield, Middlesex UB9 6JH, UK
    Philos Trans R Soc Lond B Biol Sci 362:1343-56. 2007
    ..The ultimate goal is to produce 'off-the-shelf' cells and tissues capable of inducing specific immune tolerance...
  3. ncbi request reprint Characterization of structural and signaling molecules by human valve interstitial cells and comparison to human mesenchymal stem cells
    Najma Latif
    Imperial College, National Heart and Lung Institute, Heart Science Centre, Harefield Hospital, Harefield, Middlesex UB9 6JH, UK
    J Heart Valve Dis 16:56-66. 2007
    ..A comprehensive, phenotypic analysis of MSCs and, for the latter, their comparison with valve interstitial cells (ICs) is therefore essential...
  4. ncbi request reprint Collagen synthesis by mesenchymal stem cells and aortic valve interstitial cells in response to mechanical stretch
    Ching Hsin Ku
    Department of Cardiothoracic Surgery, Heart Science Centre, Harefield Hospital, NHLI, Imperial College London, UK
    Cardiovasc Res 71:548-56. 2006
    ..We have examined and compared the capacity of mesenchymal stem cells to synthesise collagen in response to stretch in comparison with native aortic valve interstitial cells...
  5. ncbi request reprint Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells seeded on collagen scaffolds-relevance to tissue engineering
    John V Terrovitis
    Heart Science Centre, Harefield Hospital, Imperial College, London, United Kingdom
    Tissue Eng 12:2765-75. 2006
    ..Ferumoxide labeling of human MSCs seeded on collagen scaffolds is an effective, non-toxic technique for visualization of these cells using MRI. This technique appears promising for cell tracking in future tissue-engineering applications...
  6. ncbi request reprint The cardiac valve interstitial cell
    Patricia M Taylor
    Division of Cardiothoracic Surgery, National Heart and Lung Institute, Faculty of Medicine, Imperial College of Science, Technology and Medicine at Harefield Hospital, Heart Science Centre, Middlesex, Harefield, UB9 6JH, UK
    Int J Biochem Cell Biol 35:113-8. 2003
    ..In this respect, these cells exhibit a profile unlike skin fibroblasts, which may allude to their role in valve function...
  7. ncbi request reprint Loss of ecto-5'nucleotidase from porcine endothelial cells after exposure to human blood: Implications for xenotransplantation
    Zain Khalpey
    Heart Science Centre, Imperial College at Harefield Hospital, Middlesex UB9 6JH, UK
    Biochim Biophys Acta 1741:191-8. 2005
    ..This effect is triggered by human humoral immune responses, and complement contributes but does not fully mediate E5'N depletion...