T R E Barnes

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi request reprint Screening for the metabolic syndrome in community psychiatric patients prescribed antipsychotics: a quality improvement programme
    T R E Barnes
    Department of Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Campus, London, UK
    Acta Psychiatr Scand 118:26-33. 2008
  2. pmc Naturalistic follow-up of co-morbid substance use in schizophrenia: the West London first-episode study
    I Harrison
    Department of Psychological Medicine, Imperial College Faculty of Medicine, London, UK
    Psychol Med 38:79-88. 2008
  3. doi request reprint Effect of prior treatment with antipsychotic long-acting injection on randomised clinical trial treatment outcomes
    Thomas R E Barnes
    Centre for Mental Health, Imperial College, 37 Claybrook Road, London, UK
    Br J Psychiatry 203:215-20. 2013
  4. doi request reprint Role of the prescribing observatory for mental health
    Thomas R E Barnes
    Centre for Mental Health, Imperial College, 37 Claybrook Road, London W6 8RP, UK
    Br J Psychiatry 201:428-9. 2012
  5. doi request reprint Antipsychotics in dementia: prevalence and quality of antipsychotic drug prescribing in UK mental health services
    Thomas R E Barnes
    Imperial College London, and the Prescribing Observatory for Mental Health POMH, Royal College of Psychiatrists Centre for Quality Improvement, London, UK
    Br J Psychiatry 201:221-6. 2012
  6. pmc IQ as a predictor of functional outcome in schizophrenia: a longitudinal, four-year study of first-episode psychosis
    Verity C Leeson
    Department of Psychological Medicine, Imperial College London, Charing Cross Campus, St Dunstan s Road, London W6 8RP, UK
    Schizophr Res 107:55-60. 2009
  7. pmc Standards of lithium monitoring in mental health Ttrusts in the UK
    Noel Collins
    Prescribing Observatory for Mental Health, Royal College of Psychiatrists Centre for Quality Improvement, 4th Floor, Standon House, 21 Mansell Street, London E18AA, UK
    BMC Psychiatry 10:80. 2010
  8. pmc The MATISSE study: a randomised trial of group art therapy for people with schizophrenia
    Mike J Crawford
    Centre for Mental Health, Imperial College, Claybrook Road London, W6 8LN, UK
    BMC Psychiatry 10:65. 2010
  9. pmc Duration of untreated psychosis and social function: 1-year follow-up study of first-episode schizophrenia
    Thomas R E Barnes
    Department of Psychological Medicine, Imperial College Faculty of Medicine, St Dunstan s Road, London W6 8RF, UK
    Br J Psychiatry 193:203-9. 2008
  10. pmc A UK audit of screening for the metabolic side effects of antipsychotics in community patients
    Thomas R E Barnes
    Department of Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Campus, London W6 8RP, UK
    Schizophr Bull 33:1397-403. 2007

Detail Information

Publications40

  1. doi request reprint Screening for the metabolic syndrome in community psychiatric patients prescribed antipsychotics: a quality improvement programme
    T R E Barnes
    Department of Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Campus, London, UK
    Acta Psychiatr Scand 118:26-33. 2008
    ..The aim was to evaluate a quality improvement programme designed to increase screening for the metabolic syndrome in community psychiatric patients prescribed antipsychotics...
  2. pmc Naturalistic follow-up of co-morbid substance use in schizophrenia: the West London first-episode study
    I Harrison
    Department of Psychological Medicine, Imperial College Faculty of Medicine, London, UK
    Psychol Med 38:79-88. 2008
    ..The impact of co-morbid substance use in first-episode schizophrenia has not been fully explored...
  3. doi request reprint Effect of prior treatment with antipsychotic long-acting injection on randomised clinical trial treatment outcomes
    Thomas R E Barnes
    Centre for Mental Health, Imperial College, 37 Claybrook Road, London, UK
    Br J Psychiatry 203:215-20. 2013
    ..It is uncertain whether antipsychotic long-acting injection (LAI) medication in schizophrenia is associated with better clinical outcomes than oral preparations...
  4. doi request reprint Role of the prescribing observatory for mental health
    Thomas R E Barnes
    Centre for Mental Health, Imperial College, 37 Claybrook Road, London W6 8RP, UK
    Br J Psychiatry 201:428-9. 2012
    ..However, progress is gradual and gains generally modest...
  5. doi request reprint Antipsychotics in dementia: prevalence and quality of antipsychotic drug prescribing in UK mental health services
    Thomas R E Barnes
    Imperial College London, and the Prescribing Observatory for Mental Health POMH, Royal College of Psychiatrists Centre for Quality Improvement, London, UK
    Br J Psychiatry 201:221-6. 2012
    ..The potential risks of such treatment are becoming clearer, but the benefits remain uncertain. Concern about the frequency and quality of such prescribing was expressed in the National Dementia Strategy for England in 2009...
  6. pmc IQ as a predictor of functional outcome in schizophrenia: a longitudinal, four-year study of first-episode psychosis
    Verity C Leeson
    Department of Psychological Medicine, Imperial College London, Charing Cross Campus, St Dunstan s Road, London W6 8RP, UK
    Schizophr Res 107:55-60. 2009
    ..This study suggests that early in the course of schizophrenia, general cognitive ability, as measured by IQ, is a more sensitive and reliable predictor of functional outcome than measures of specific ability...
  7. pmc Standards of lithium monitoring in mental health Ttrusts in the UK
    Noel Collins
    Prescribing Observatory for Mental Health, Royal College of Psychiatrists Centre for Quality Improvement, 4th Floor, Standon House, 21 Mansell Street, London E18AA, UK
    BMC Psychiatry 10:80. 2010
    ..Adherence to these recommendations has not been subject to national UK audit...
  8. pmc The MATISSE study: a randomised trial of group art therapy for people with schizophrenia
    Mike J Crawford
    Centre for Mental Health, Imperial College, Claybrook Road London, W6 8LN, UK
    BMC Psychiatry 10:65. 2010
    ..The MATISSE study aims to evaluate the clinical and cost effectiveness of group Art Therapy for people with schizophrenia...
  9. pmc Duration of untreated psychosis and social function: 1-year follow-up study of first-episode schizophrenia
    Thomas R E Barnes
    Department of Psychological Medicine, Imperial College Faculty of Medicine, St Dunstan s Road, London W6 8RF, UK
    Br J Psychiatry 193:203-9. 2008
    ..In first-episode schizophrenia, longer duration of untreated psychosis (DUP) predicts poorer outcomes...
  10. pmc A UK audit of screening for the metabolic side effects of antipsychotics in community patients
    Thomas R E Barnes
    Department of Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Campus, London W6 8RP, UK
    Schizophr Bull 33:1397-403. 2007
    ....
  11. doi request reprint Evidence-based guidelines for the pharmacological treatment of schizophrenia: recommendations from the British Association for Psychopharmacology
    Thomas R E Barnes
    Centre for Mental Health, Imperial College, Charing Cross Campus, London, UK
    J Psychopharmacol 25:567-620. 2011
    ..They are accompanied by a more detailed qualitative review of the available evidence. The strength of supporting evidence for each recommendation is rated...
  12. doi request reprint Antipsychotic polypharmacy in schizophrenia: benefits and risks
    Thomas R E Barnes
    Division of Experimental Medicine, Centre for Mental Health, Imperial College London, Charing Cross Campus, London, UK
    CNS Drugs 25:383-99. 2011
    ..Further, their prescription for each patient should be in the context of an individual trial, with monitoring of the clinical response and adverse effects, and appropriate physical health monitoring...
  13. ncbi request reprint The Barnes Akathisia Rating Scale--revisited
    Thomas R E Barnes
    Department of Psychological Medicine, Imperial College, Charing Cross Campus, London, UK
    J Psychopharmacol 17:365-70. 2003
    ..Subsequently, its validity and reliability have been established, and it has been used extensively in clinical studies worldwide...
  14. ncbi request reprint Nocturnal enuresis with antipsychotic medication
    Thomas R E Barnes
    Imperial College London, Centre for Mental Health, Faculty of Medicine, The Claybrook Centre, 37 Claybrook Road, London, W6 8LN, UK
    Br J Psychiatry 200:7-9. 2012
    ..Direct but sensitive questioning may be required to elicit this side-effect. We briefly review possible mechanisms of this problem, and management and treatment options...
  15. doi request reprint Improving prescribing practice in psychiatry: the experience of the Prescribing Observatory for Mental Health (POMH-UK)
    Thomas R E Barnes
    Centre for Mental Health, Imperial College, London, and Prescribing Observatory for Mental Health, Centre for Quality Improvement, Royal College of Psychiatrists, UK
    Int Rev Psychiatry 23:328-35. 2011
    ..In this QIP there was little improvement in overall performance against the clinical standards in the total national sample between baseline and re-audit...
  16. ncbi request reprint Comorbid substance use and age at onset of schizophrenia
    Thomas R E Barnes
    Department of Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Campus, St Dunstan s Road, London W6 8RP, UK
    Br J Psychiatry 188:237-42. 2006
    ..Substance use may be a risk factor for the onset of schizophrenia...
  17. pmc Abnormal negative feedback processing in first episode schizophrenia: evidence from an oculomotor rule switching task
    V C Huddy
    Institute of Psychiatry, Kings College London, London, UK
    Psychol Med 41:1805-14. 2011
    ..The present study used an oculomotor 'rule switching' task to investigate the use of negative feedback when switching between task rules in people with schizophrenia...
  18. ncbi request reprint Clinical correlates of early medication adherence: West London first episode schizophrenia study
    S H Mutsatsa
    Department of Psychological Medicine, Imperial College Faculty of Medicine, St Dunstans Road, London W68 8RP, U K
    Acta Psychiatr Scand 108:439-46. 2003
    ..This study sought to identify factors that may be associated with medication adherence in first-episode schizophrenia...
  19. pmc Impaired conscious and preserved unconscious inhibitory processing in recent onset schizophrenia
    V C Huddy
    Division of Neuroscience and Mental Health, Imperial College London, UK
    Psychol Med 39:907-16. 2009
    ..As response inhibition is known to occur in both voluntary and involuntary processes, an important question is whether both aspects of response inhibition are specifically impaired in people with schizophrenia...
  20. pmc Do patients with schizophrenia exhibit aberrant salience?
    J P Roiser
    Institute of Cognitive Neuroscience, University College London, London, UK
    Psychol Med 39:199-209. 2009
    ..To test this hypothesis we investigated whether patients with schizophrenia showed impaired learning of task-relevant stimulus-reinforcement associations in the presence of distracting task-irrelevant cues...
  21. doi request reprint Medication prescribed to people with personality disorder: the influence of patient factors and treatment setting
    M J Crawford
    Centre for Mental Health, Imperial College London, UK
    Acta Psychiatr Scand 124:396-402. 2011
    ..To examine the extent of use and clinical rationale for the prescribing of psychotropic drugs for people with personality disorder (PD) who are in contact with mental health services...
  22. ncbi request reprint Saccadic distractibility in first-episode schizophrenia
    S B Hutton
    Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine, Charing Cross Hospital, London, UK
    Neuropsychologia 40:1729-36. 2002
    ..Possible explanations of these results include reduced working memory resources and impaired motor preparation in schizophrenia...
  23. ncbi request reprint Pharmacological management of acute mania: does current prescribing practice reflect treatment guidelines?
    A Streeruwitz
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    J Psychopharmacol 21:206-9. 2007
    ..The findings reinforce the value of prescribing surveys in mental health and the need to share understanding of the constraints that may lead to deviation from prescribing guidelines...
  24. doi request reprint Interrater reliability of the Antipsychotic Non-Neurological Side-Effects Rating Scale measured in patients treated with clozapine
    R I Ohlsen
    MRC SGDP Centre and Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, London, UK
    J Psychopharmacol 22:323-9. 2008
    ....
  25. pmc White matter tracts in first-episode psychosis: a DTI tractography study of the uncinate fasciculus
    Gary Price
    Institute of Neurology, University College London, Queen Square, London, UK
    Neuroimage 39:949-55. 2008
    ..The SCV of FA was lower in females across both groups and there was no correlation between the SCV of FA and clinical ratings...
  26. ncbi request reprint The determinants and effect of shared care on patient outcomes and psychiatric admissions - an inner city primary care cohort study
    Natalie K Fitzpatrick
    Department of Public Health Research, Westminster Primary Care Trust, Westminster Primary Care Trust Headquarters, 15 Marylebone Road, London NW1 5JD, UK
    Soc Psychiatry Psychiatr Epidemiol 39:154-63. 2004
    ..The aim of this study was to determine the factors associated with receipt of different levels of shared care, and the effect of shared care on patient outcomes...
  27. ncbi request reprint Structural neural networks subserving oculomotor function in first-episode schizophrenia
    Manjinder S Bagary
    Institute of Neurology, University College London, Queens Square, London WC1N 3BG, United Kingdom
    Biol Psychiatry 56:620-7. 2004
    ..Smooth pursuit and antisaccade abnormalities are well documented in schizophrenia, but their neuropathological correlates remain unclear...
  28. ncbi request reprint Cognitive heterogeneity in first-episode schizophrenia
    Eileen M Joyce
    Institute of Neurology, University College London, Box 19, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Br J Psychiatry 187:516-22. 2005
    ..Studies of chronic schizophrenia suggest that there are subgroups with different profiles of cognitive impairment...
  29. pmc Randomized controlled trial of effect of prescription of clozapine versus other second-generation antipsychotic drugs in resistant schizophrenia
    Shon W Lewis
    University of Manchester, London
    Schizophr Bull 32:715-23. 2006
    ..In conclusion, in people with schizophrenia with poor treatment response to 2 or more antipsychotic drugs, there is an advantage to commencing clozapine rather than other SGA drugs in terms of symptom improvement over 1 year...
  30. ncbi request reprint Relationship between insight, cognitive function, social function and symptomatology in schizophrenia: the West London first episode study
    Stanley H Mutsatsa
    Department of Psychological Medicine, Imperial College, St Dunstan s Road, London, W6 8RP
    Eur Arch Psychiatry Clin Neurosci 256:356-63. 2006
    ..To examine the nature and clinical correlates of insight in first-episode schizophrenia, and how these differ from findings in established schizophrenia...
  31. ncbi request reprint Randomized controlled trial of the effect on Quality of Life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1)
    Peter B Jones
    Department of Psychiatry, University of Cambridge and Cambridgeshire and Peterborough Mental Health NHS Trust, Cambridge, England
    Arch Gen Psychiatry 63:1079-87. 2006
    ..Most evidence comes from short-term efficacy trials of symptoms...
  32. ncbi request reprint Prevalence and nature of side effects during clozapine maintenance treatment and the relationship with clozapine dose and plasma concentration
    Babur Yusufi
    West London Mental Health NHS Trust, Guy s and St Thomas NHS Foundation Trust, Department of Psychological Medicine, London, UK
    Int Clin Psychopharmacol 22:238-43. 2007
    ..The use of target plasma concentrations below those used for acute treatment should be explored as a strategy for minimizing side effects...
  33. ncbi request reprint Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
    Theresa H M Moore
    Academic Unit of Psychiatry, University of Bristol, Bristol, UK
    Lancet 370:319-28. 2007
    ..We systematically reviewed the evidence pertaining to cannabis use and occurrence of psychotic or affective mental health outcomes...
  34. doi request reprint High-dose and combination antipsychotic prescribing in acute adult wards in the UK: the challenges posed by p.r.n. prescribing
    Carol Paton
    Oxleas NHS Foundation Trust, Pinewood House, Pinewood Place, Dartford, Kent DA2 7WG, UK
    Br J Psychiatry 192:435-9. 2008
    ..Clinical guidelines recommend the routine use of a single antipsychotic drug in a standard dose, but prescriptions for high-dose and combined antipsychotics are common in clinical practice...
  35. ncbi request reprint A randomized controlled trial of cognitive-behavior therapy for persistent symptoms in schizophrenia: a five-year follow-up
    Douglas Turkington
    School of Neurology, Neurobiology and Psychiatry, Royal Victoria Infirmary, Leazes Wing, Richardson Road, University of Newcastle, Newcastle upon Tyne, Tyne and Wear, NE1 4LP, UK
    Schizophr Res 98:1-7. 2008
    ..The initial cost of an adjunctive course of CBT for individuals with medication refractory schizophrenia may be justified in light of symptomatic benefits that persist over the medium term...
  36. pmc Abnormal brain connectivity in first-episode psychosis: a diffusion MRI tractography study of the corpus callosum
    Gary Price
    Department of Neuroinflammation, Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK
    Neuroimage 35:458-66. 2007
    ..The FA reduction in patients may be due to aberrant myelination or axonal abnormalities, but the similar tract volumes in the two groups suggest that severe axonal loss is unlikely at this stage of the illness...
  37. ncbi request reprint A volumetric MRI and magnetization transfer imaging follow-up study of patients with first-episode schizophrenia
    Gary Price
    Department of Neuroinflammation, Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK
    Schizophr Res 87:100-8. 2006
    ..The results of the study need to be interpreted in the light of the small sample size and of the limitations of current image analysis methods...
  38. pmc Gaze strategies during planning in first-episode psychosis
    Vyv C Huddy
    Division of Neuroscience and Mental Health, Imperial College London, London, England
    J Abnorm Psychol 116:589-98. 2007
    ..This suggests that the patients had difficulty in encoding the essential features of the stimulus array. This finding is compatible with slowing of working memory consolidation...
  39. ncbi request reprint The relationship between antisaccades, smooth pursuit, and executive dysfunction in first-episode schizophrenia
    Samuel B Hutton
    Department of Psychology, University of Sussex, Brighton, UK
    Biol Psychiatry 56:553-9. 2004
    ....
  40. ncbi request reprint Relapse prevention in schizophrenia with new-generation antipsychotics: a systematic review and exploratory meta-analysis of randomized, controlled trials
    Stefan Leucht
    Klinik and Poliklinik für Psychiatrie und Psychotherapie der Technichen Universität München, Germany
    Am J Psychiatry 160:1209-22. 2003
    ..The authors performed a systematic review and meta-analysis of studies of the potential of new-generation antipsychotic drugs to improve adherence and decrease relapse rates in patients with schizophrenia...