I M Balfour-Lynn

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi request reprint Deaths in childhood from cystic fibrosis: 10-year analysis from two London specialist centres
    Donald S Urquhart
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, Sydney Street, London SW3 6NP, UK
    Arch Dis Child 98:123-7. 2013
  2. doi request reprint Domiciliary oxygen for children
    Ian M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Pediatr Clin North Am 56:275-96, xiii. 2009
  3. pmc Cystic fibrosis papers of the year 2007
    Ian M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust Sydney Street, London SW3 6NP, UK
    J R Soc Med 101:S10-4. 2008
  4. ncbi request reprint Newborn screening for cystic fibrosis: evidence for benefit
    Ian M Balfour-Lynn
    Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Arch Dis Child 93:7-10. 2008
  5. ncbi request reprint Anti-inflammatory approaches to cystic fibrosis airways disease
    Ian M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Curr Opin Pulm Med 13:522-8. 2007
  6. ncbi request reprint Multicenter randomized controlled trial of withdrawal of inhaled corticosteroids in cystic fibrosis
    Ian M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, and National Heart and Lung Institute, Imperial College London, SW3 6NP, UK
    Am J Respir Crit Care Med 173:1356-62. 2006
  7. pmc BTS guidelines for the management of pleural infection in children
    I M Balfour-Lynn
    Consultant in Paediatric Respiratory Medicine, Royal Brompton Hospital, Syndey St, SW3 6NP London, UK
    Thorax 60:i1-21. 2005
  8. pmc Intravenous immunoglobulin for cystic fibrosis lung disease: a case series of 16 children
    I M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, Sydney Street, London, UK
    Arch Dis Child 89:315-9. 2004
  9. pmc Asthma in cystic fibrosis
    Ian M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, Sydney Street, London SW3 6NP, UK
    J R Soc Med 96:30-4. 2003
  10. pmc "CF asthma": what is it and what do we do about it?
    I M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London SW3 6NP, UK
    Thorax 57:742-8. 2002

Collaborators

Detail Information

Publications38

  1. doi request reprint Deaths in childhood from cystic fibrosis: 10-year analysis from two London specialist centres
    Donald S Urquhart
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, Sydney Street, London SW3 6NP, UK
    Arch Dis Child 98:123-7. 2013
    ..Death in childhood from cystic fibrosis (CF) is now an uncommon event in the U.K. We wished to assess the circumstances surrounding deaths (and lung transplantation) in the modern era of CF care...
  2. doi request reprint Domiciliary oxygen for children
    Ian M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Pediatr Clin North Am 56:275-96, xiii. 2009
    ..Nevertheless, many children benefit from receiving supplemental oxygen at home, particularly because it helps to keep them out of the hospital...
  3. pmc Cystic fibrosis papers of the year 2007
    Ian M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust Sydney Street, London SW3 6NP, UK
    J R Soc Med 101:S10-4. 2008
  4. ncbi request reprint Newborn screening for cystic fibrosis: evidence for benefit
    Ian M Balfour-Lynn
    Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Arch Dis Child 93:7-10. 2008
  5. ncbi request reprint Anti-inflammatory approaches to cystic fibrosis airways disease
    Ian M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Curr Opin Pulm Med 13:522-8. 2007
    ..Therapy aimed at combating excessive lung inflammation should benefit patients with cystic fibrosis. This article reviews anti-inflammatory strategies, focusing on new evidence published since 2006...
  6. ncbi request reprint Multicenter randomized controlled trial of withdrawal of inhaled corticosteroids in cystic fibrosis
    Ian M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, and National Heart and Lung Institute, Imperial College London, SW3 6NP, UK
    Am J Respir Crit Care Med 173:1356-62. 2006
    ..Lung inflammation and injury is critical in cystic fibrosis. An ideal antiinflammatory agent has not been identified but inhaled corticosteroids are widely used despite lack of evidence...
  7. pmc BTS guidelines for the management of pleural infection in children
    I M Balfour-Lynn
    Consultant in Paediatric Respiratory Medicine, Royal Brompton Hospital, Syndey St, SW3 6NP London, UK
    Thorax 60:i1-21. 2005
  8. pmc Intravenous immunoglobulin for cystic fibrosis lung disease: a case series of 16 children
    I M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, Sydney Street, London, UK
    Arch Dis Child 89:315-9. 2004
    ..In an attempt to reduce the use of regular oral corticosteroids, we treated a group of such children with monthly courses of intravenous immunoglobulin (IVIG)...
  9. pmc Asthma in cystic fibrosis
    Ian M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, Sydney Street, London SW3 6NP, UK
    J R Soc Med 96:30-4. 2003
  10. pmc "CF asthma": what is it and what do we do about it?
    I M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London SW3 6NP, UK
    Thorax 57:742-8. 2002
    ..This may not matter, however; the relevance lies in the possible approaches to treatment...
  11. ncbi request reprint Bronchoscopy--how and when?
    Ian M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, Sydney Street, London SW3 6NP, UK
    Paediatr Respir Rev 3:255-64. 2002
    ..Particular attention is paid to indications and contraindications, as well as potential complications...
  12. ncbi request reprint Effect of intravenous antibiotics on exercise tolerance (3-min step test)) in cystic fibrosis
    S E Pike
    Department of Physiotherapy, Royal Brompton and Harefield NHS Trust, London, UK
    Pediatr Pulmonol 32:38-43. 2001
    ..The simple ward-based 3-min step test was found to be a particularly suitable method for measuring changes in exercise tolerance in children with CF...
  13. pmc Corticosteroid responsiveness and clinical characteristics in childhood difficult asthma
    C J Bossley
    Dept of Respiratory Paediatrics, Royal Brompton Hospital, London SW3 6NP, UK
    Eur Respir J 34:1052-9. 2009
    ..93, 95% CI 0.90-0.97). Only 11% of DA children exhibited complete corticosteroid responsiveness. The rarity of complete corticosteroid responsiveness suggests alternative therapies are needed for children with DA...
  14. doi request reprint Fitness to fly testing in term and ex-preterm babies without bronchopulmonary dysplasia
    C J Bossley
    Royal Brompton Hospital, London, UK
    Arch Dis Child Fetal Neonatal Ed 97:F199-203. 2012
    ..The consequences of feeding a baby during the hypoxia challenge were also unknown...
  15. ncbi request reprint Three-minute step test to assess exercise capacity in children with cystic fibrosis with mild lung disease
    I Narang
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Pediatr Pulmonol 35:108-13. 2003
    ..The 15c did not discriminate between a maximal and a submaximal test, and was less useful than VAS. Important information may be missed by the step test which is detected by more complex exercise tests...
  16. ncbi request reprint Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial
    A Equi
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Lancet 360:978-84. 2002
    ..The macrolide antibiotic azithromycin has anti-inflammatory properties potentially beneficial in cystic fibrosis. Since findings of open pilot studies seemed to show clinical benefit, we undertook a formal trial...
  17. pmc Growth and lung function in Asian patients with cystic fibrosis
    B D Callaghan
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, UK
    Arch Dis Child 90:1029-32. 2005
    ..The incidence of cystic fibrosis (CF) in Asians is rare. How these patients fare in terms of morbidity and mortality in the UK compared to their non-Asian peers is not well documented...
  18. ncbi request reprint Children with difficult asthma: a practical approach
    D N Payne
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, UK
    J Asthma 38:189-203. 2001
    ..Identification of different pathological subtypes of severe asthma should allow for more rational prescribing of asthma therapy, as well as the design of further trials of potential steroid-sparing treatments...
  19. ncbi request reprint Exercise tolerance in children with cystic fibrosis undergoing lung transplantation assessment
    P Aurora
    Cardiorespiratory and Critical Care Directorate, Great Ormond Street Hospital for Children, London, UK
    Eur Respir J 18:293-7. 2001
    ..The 3-min step test produced a greater fall in Sa,O2 and a greater rise in HR than the 6-min walk test in children with moderate to severe CF lung disease. It may be of value when assessing a child's suitability for lung transplantation...
  20. ncbi request reprint A comparison of the prevalence of urinary incontinence in girls with cystic fibrosis, asthma, and healthy controls
    S A Prasad
    Great Ormond Street Hospital for Children, London, UK
    Pediatr Pulmonol 41:1065-8. 2006
    ..Surprisingly it is perceived as a relatively minor problem in terms of the distress it causes. Pediatric CF clinics should be routinely addressing UI as a potential problem in all girls from the age of 11 years...
  21. ncbi request reprint Incidence and outcome of scoliosis in children with pleural infection
    S Mukherjee
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, United Kingdom
    Pediatr Pulmonol 42:221-4. 2007
    ..To ascertain the incidence and outcome of secondary scoliosis associated with parapneumonic effusions/empyema...
  22. ncbi request reprint Tumour necrosis factor gene polymorphisms and childhood wheezing
    H Bilolikar
    Dept of Paediatric Respiratory Medicine, Royal BromptonHospital, Sydney Street, London SW3 6NP, UK
    Eur Respir J 26:637-46. 2005
    ..In conclusion, these findings may have implications for future early intervention studies by helping to identify infants at increased risk for wheezing and childhood asthma...
  23. doi request reprint Use of home oxygen for children in England and Wales
    R A Primhak
    Department of Paediatric Respiratory Medicine, Sheffield Children s Hospital, Sheffield, UK
    Arch Dis Child 96:389-92. 2011
    ..The authors' aim was to determine the incidence and patterns of home oxygen prescribing...
  24. ncbi request reprint Cystic fibrosis presenting with haematological abnormalities
    C C Minasian
    Department of Paediatric Respiratory Medicine, Imperial College and Royal Brompton Hospital, Sydney Street, London, UK
    Clin Lab Haematol 28:423-6. 2006
    ..We present three cases of children with CF who presented with haematological abnormalities. In all cases, they underwent extensive and invasive investigations prior to the diagnosis...
  25. ncbi request reprint Inflammatory endobronchial polyps in childhood: clinical spectrum and possible link to mechanical ventilation
    D McShane
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, UK
    Pediatr Pulmonol 34:79-84. 2002
    ..The small caliber of the main airways in neonates may also be a contributory factor in presentation...
  26. doi request reprint Growth in children with cystic fibrosis-related diabetes
    M S Cheung
    Chelsea and Westminster Hospital, London, UK
    Pediatr Pulmonol 44:1223-5. 2009
    ..It would be useful to know whether early treatment with insulin can help promote catch up growth...
  27. pmc Home oxygen for children: who, how and when?
    I M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Thorax 60:76-81. 2005
    ..A review of the specific requirements of home oxygen therapy in children which attempts to offer guidance to clinicians and service providers...
  28. ncbi request reprint Taking young children on aeroplanes: what are the risks?
    C Bossley
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Arch Dis Child 93:528-33. 2008
  29. ncbi request reprint Quality, size, and composition of pediatric endobronchial biopsies in cystic fibrosis
    Nicolas Regamey
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Chest 131:1710-7. 2007
    ..We prospectively assessed how the quality of biopsy specimens obtained from children with CF compare with those from children with other airway diseases...
  30. pmc Are annual blood tests in preschool cystic fibrosis patients worthwhile?
    A Jaffe
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, Sydney Street, London SW3 6NP, UK
    Arch Dis Child 87:518-20. 2002
    ..Aim: To investigate whether routine annual assessment blood tests in cystic fibrosis (CF) patients under 5 years influence management...
  31. doi request reprint Increased incidence of bronchopulmonary fistulas complicating pediatric pneumonia
    A J McKee
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, Royal Brompton and Harefield NHS Foundation Trust, Sydney Street, London, UK
    Pediatr Pulmonol 46:717-21. 2011
    ..During 2008-2009, we noted an increase in the number of children whose empyema was complicated by the development of a bronchopleural fistula and air leak. We studied these children to see if there was an associated cause...
  32. ncbi request reprint Thrombophilia in children with cystic fibrosis
    I M Balfour-Lynn
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Pediatr Pulmonol 39:306-10. 2005
    ..We recommend that thrombophilia screening be performed prior to insertion of a TIVAD, and also in those with a history of venous thrombosis, blocked TIVADs, or recurring problems with long lines...
  33. ncbi request reprint Subcutaneous terbutaline in children with chronic severe asthma
    Donald N R Payne
    Department of Respiratory Medicine, Royal Brompton Hospital, London, UK
    Pediatr Pulmonol 33:356-61. 2002
    ..These initial findings support the need for further controlled studies to evaluate the use of CSIT in severe childhood asthma...
  34. ncbi request reprint Is this baby fit to fly? Hypoxia in aeroplanes
    Cara Bossley
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Early Hum Dev 83:755-9. 2007
    ..The British Thoracic Society 2004 guideline currently recommends supplemental oxygen be given if the child's oxygen saturation falls below 90% during the test, although 85% may be a more appropriate cut off level...
  35. doi request reprint Diagnosing allergic bronchopulmonary aspergillosis in children with cystic fibrosis
    Lena P Thia
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Paediatr Respir Rev 10:37-42. 2009
    ....
  36. ncbi request reprint Treatment of severe small airways disease in children with cystic fibrosis: alternatives to corticosteroids
    Adam Jaffe
    Department of Respiratory Medicine, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
    Paediatr Drugs 4:381-9. 2002
    ..The order in which they are attempted is unclear, but it would be sensible to try the least invasive medication with the least adverse effects first, moving on to more potent, but more toxic drugs if that treatment fails...
  37. ncbi request reprint Management of empyema in children
    Adam Jaffe
    Portex Respiratory Medicine Group, Great Ormond Street Hospital for Children, National Health System Trust and Institute of Child Health, London, UK
    Pediatr Pulmonol 40:148-56. 2005
    ..There is an urgent need for this to be addressed, particularly with the introduction of relatively new surgical techniques such as video-assisted thorascopic surgery...
  38. doi request reprint Endobronchial biopsy in childhood
    Nicolas Regamey
    Chest 133:312; author reply 313. 2008