Stephanie Ascough

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. pmc Anthrax lethal toxin and the induction of CD4 T cell immunity
    Stephanie Ascough
    Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College, Hammersmith Hospital, London, UK
    Toxins (Basel) 4:878-99. 2012
  2. pmc Anthrax Lethal Factor as an Immune Target in Humans and Transgenic Mice and the Impact of HLA Polymorphism on CD4+ T Cell Immunity
    Stephanie Ascough
    Department of Medicine, Imperial College London, London, United Kingdom
    PLoS Pathog 10:e1004085. 2014
  3. doi request reprint Th1 not Th17 cells drive spontaneous MS-like disease despite a functional regulatory T cell response
    Daniel E Lowther
    Human Disease Immunogenetics Group, Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College, Hammersmith Hospital, London, W12 0NN, UK
    Acta Neuropathol 126:501-15. 2013

Collaborators

Detail Information

Publications3

  1. pmc Anthrax lethal toxin and the induction of CD4 T cell immunity
    Stephanie Ascough
    Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College, Hammersmith Hospital, London, UK
    Toxins (Basel) 4:878-99. 2012
    ..We discuss how LT affects the adaptive immune response and specifically the identification of B. anthracis epitopes that are both immunogenic and protective with the potential for inclusion in protein sub-unit based vaccines...
  2. pmc Anthrax Lethal Factor as an Immune Target in Humans and Transgenic Mice and the Impact of HLA Polymorphism on CD4+ T Cell Immunity
    Stephanie Ascough
    Department of Medicine, Imperial College London, London, United Kingdom
    PLoS Pathog 10:e1004085. 2014
    ..The ability of the identified epitopes to confer protective immunity was demonstrated by lethal anthrax challenge of HLA transgenic mice immunized with a peptide subunit vaccine comprising the immunodominant epitopes that we identified. ..
  3. doi request reprint Th1 not Th17 cells drive spontaneous MS-like disease despite a functional regulatory T cell response
    Daniel E Lowther
    Human Disease Immunogenetics Group, Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College, Hammersmith Hospital, London, W12 0NN, UK
    Acta Neuropathol 126:501-15. 2013
    ....