P M Hughes

Summary

Country: UK

Publications

  1. ncbi Comparison of matrix metalloproteinase expression during Wallerian degeneration in the central and peripheral nervous systems
    P M Hughes
    Nurin Ltd, CNS Inflammation Group, Biomedical Sciences Building, University of Southampton, Southampton SO16 7PX, UK
    Neuroscience 113:273-87. 2002
  2. ncbi T-cell- and macrophage-mediated axon damage in the absence of a CNS-specific immune response: involvement of metalloproteinases
    T A Newman
    CNS Inflammation Group, School of Biological Sciences, University of Southampton, UK
    Brain 124:2203-14. 2001
  3. ncbi Focal lesions in the rat central nervous system induced by endothelin-1
    P M Hughes
    Nurin Ltd, Southampton, United Kingdom
    J Neuropathol Exp Neurol 62:1276-86. 2003

Collaborators

Detail Information

Publications3

  1. ncbi Comparison of matrix metalloproteinase expression during Wallerian degeneration in the central and peripheral nervous systems
    P M Hughes
    Nurin Ltd, CNS Inflammation Group, Biomedical Sciences Building, University of Southampton, Southampton SO16 7PX, UK
    Neuroscience 113:273-87. 2002
    ....
  2. ncbi T-cell- and macrophage-mediated axon damage in the absence of a CNS-specific immune response: involvement of metalloproteinases
    T A Newman
    CNS Inflammation Group, School of Biological Sciences, University of Southampton, UK
    Brain 124:2203-14. 2001
    ..Our results show that axon injury, possibly mediated by MMPs, is immunologically non-specific and may continue behind an intact blood-brain barrier...
  3. ncbi Focal lesions in the rat central nervous system induced by endothelin-1
    P M Hughes
    Nurin Ltd, Southampton, United Kingdom
    J Neuropathol Exp Neurol 62:1276-86. 2003
    ..Focal injections of endothelin-1 into specific areas of the rat CNS represent a model to investigate therapeutic approaches to white matter ischemia...