Research Topics
| Noel W ClarkeSummaryAffiliation: Hope Hospital Country: UK Publications
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Detail Information
Publications
Management of the spectrum of hormone refractory prostate cancerNoel W Clarke
Christie Hospital and Salford Royal Hospitals NHS Trusts, Manchester, UK
Eur Urol 50:428-38; discussion 438-9. 2006..Aim of this review was to critically evaluate the current and potential approaches to patients affected by HRPC...
Classification of fixed urological cells using Raman tweezersTim J Harvey
School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, UK
J Biophotonics 2:47-69. 2009..Results indicate that urine has no detrimental effect on prediction results...- Investigating FTIR based histopathology for the diagnosis of prostate cancerMatthew J Baker
Manchester Interdisciplinary Biocentre, Centre for Instrumentation and Analytical Science, School of Chemical Engineering and Analytical Science, The University of Manchester, 131 Princess Street, Manchester, UK
J Biophotonics 2:104-13. 2009..In this paper we report the results of a large patient study in which FTIR has been proven to grade CaP tissue specimens to a high degree of sensitivity and specificity... - Measurement of elastic properties of prostate cancer cells using AFMElsa Correia Faria
School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, The University of Manchester, Manchester, UK
Analyst 133:1498-500. 2008.... - Discrimination of prostate cancer cells by reflection mode FTIR photoacoustic spectroscopyTim J Harvey
School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, UK
Analyst 132:292-5. 2007.... - Direct evidence of lipid translocation between adipocytes and prostate cancer cells with imaging FTIR microspectroscopyEhsan Gazi
ProMPT Genito Urinary Cancer Research Group, Paterson Institute for Cancer Research, The University of Manchester, Manchester, UK
J Lipid Res 48:1846-56. 2007.... 
Characterization of the Hoechst 33342 side population from normal and malignant human renal epithelial cellsSanjai K Addla
Genito Urinary Cancer Research Group, School of Cancer and Imaging Sciences, Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester, UK
Am J Physiol Renal Physiol 295:F680-7. 2008..The population is, however, heterogeneous, confirming that the terms "SP cell" and "stem cell" cannot be used interchangeably...- FTIR microscopy of biological cells and tissue: data analysis using resonant Mie scattering (RMieS) EMSC algorithmPaul Bassan
Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK
Analyst 137:1370-7. 2012..Importantly however, we show that using three different non-ideal reference spectra, the same unique correction solution can be obtained... - Molecular mechanisms of metastasis in prostate cancerNoel W Clarke
Genito Urinary Cancer Research Group, School of Cancer and Imaging Sciences, Paterson Institute for Cancer Research, Christie Hospital, University of Manchester, Manchester, UK
Asian J Androl 11:57-67. 2009..In this review, we present the current understanding of the molecular processes driving PCa metastasis to the bone... - Characterization of benign and malignant prostate epithelial Hoechst 33342 side populationsMick D Brown
ProMPT Genito Urinary Cancer Research Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK
Prostate 67:1384-96. 2007..The prostate epithelial stem cell has been proposed as the primary origin of neoplastic change in prostate cancer. However, the isolation and characterization of unexpanded prostate epithelial stem cells have proven problematic... - A correlation of FTIR spectra derived from prostate cancer biopsies with gleason grade and tumour stageEhsan Gazi
School of Chemical Engineering and Analytical Science, University of Manchester, Manchester, UK
Eur Urol 50:750-60; discussion 760-1. 2006..For the first time, we correlate FTIR spectra derived from prostate cancer (pCA) tissue with Gleason score and the clinical stage of the tumour at time of biopsy... - FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladderCaryn Hughes
Manchester Institute of Biotechnology, University of Manchester, Manchester, UK
J Biophotonics 6:73-87. 2013..As shown, their spectroscopic signals can change dramatically as a consequence of differentiation. Example cases are discussed and compared with histological evaluations... - Early prostate cancer--which treatment do men prefer and why?Carmel N Anandadas
Department of Clinical Oncology, the Christie NHS Foundation Trust, Manchester, UK
BJU Int 107:1762-8. 2011..Preference (prospective cohort)... - Differential inhibition of invasion and proliferation by bisphosphonates: anti-metastatic potential of Zoledronic acid in prostate cancerRichard Montague
Genito-Urinary Cancer Research Group, Kay Kendall Laboratory, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Wilmslow Road, Manchester, M20 4BX, UK
Eur Urol 46:389-401; discussion 401-2. 2004..CONCLUSION: Zoledronic acid is a potent inhibitor of PEC invasion across bone marrow endothelium and colony formation with the bone marrow stroma, affecting the MMP: TIMP-2 balance to favour MMP inhibition... - The molecular staging of prostate cancerIain G McIntyre
Genito-Urinary Cancer Research Group, Christie Hospital, Manchester, UK
BJU Int 94:1217-20. 2004 - Landmarks in non-hormonal pharmacological therapies for castration-resistant prostate cancerNoel W Clarke
The Christie and Salford Royal Hospitals, Manchester, UK
BJU Int 110:14-22. 2012..Most of these remain experimental but on-going pharmacological development will inevitably provide urologists and urological oncologists with a broader range of therapeutic options for better cancer management in the future... - The increased rate of prostate specific antigen testing has not affected prostate cancer presentation in an inner city population in the UKMoeketsi Mokete
Department of Urology, Hope Hospital, Salford Royal Hospitals NHS Trust, Salford, Manchester, UK
BJU Int 97:266-9. 2006..While there was an increase in PSA testing during the study period, the testing rate remains much lower than in other reported series from the UK... - A contemporary standard for morbidity and outcome after radical cystectomyVijay A C Ramani
Department of Urology, the Christie NHS Foundation Trust, Manchester, UK
BJU Int 104:628-32. 2009.... - Chemotherapy in hormone refractory prostate cancer: where do we stand?Noel W Clarke
Eur Urol 46:709-11. 2004 - Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometryMatthew J Baker
Manchester Interdisciplinary Biocentre, Centre for Instrumentation and Analytical Science, School of Chemical Engineering and Analytical Science, The University of Manchester, UK
Analyst 133:175-9. 2008.... - The origin of the bone scan as a tumour marker in prostate cancerNoel W Clarke
Eur Urol 50:873-8. 2006 - The natural history of postoperative renal function in patients undergoing ileal conduit diversion for cancer measured using serial isotopic glomerular filtration rate and 99m technetium-mercaptoacetyltriglycine renographyJoanne D Samuel
Departments of Urology, Christie Hospital, Salford, United Kingdom
J Urol 176:2518-22; discussion 2522. 2006..In 11% of patients deterioration was due to upper tract obstruction. This was identifiable using renography and the glomerular filtration rate. A type IIIb curve was an early indicator of obstruction... - Radiotherapy and androgen deprivation in combination after local surgery (RADICALS): a new Medical Research Council/National Cancer Institute of Canada phase III trial of adjuvant treatment after radical prostatectomyChris Parker
Academic Unit of Radiotherapy and Oncology, Institute of Cancer Research and the Royal, Marsden NHS Foundation Trust, Sutton, Surrey, UK
BJU Int 99:1376-9. 2007 - The influence of lipid metabolism on prostate cancer development and progression: is it time for a closer look?Noel W Clarke
Eur Urol 52:3-4. 2007 - Early hormonal data from a multicentre phase II trial using transdermal oestrogen patches as first-line hormonal therapy in patients with locally advanced or metastatic prostate cancerRuth E Langley
Endocrinology and Metabolic Medicine, Imperial College, London, UK
BJU Int 102:442-5. 2008..To assess the hormonal effects of Fem7 (Merck, KGaA, Darmstadt, Germany) 100 microg transdermal oestrogen patches on men undergoing first-line androgen-deprivation therapy for prostate cancer... - Optical artefacts in transflection mode FTIR microspectroscopic images of single cells on a biological support: the effect of back-scattering into collection opticsJoe Lee
School of Chemistry, University of Manchester, P O Box 88, Manchester, UK M60 1QD
Analyst 132:750-5. 2007..This leads to an apparent reduction in absorption at the cell...