Noel W Clarke

Summary

Affiliation: Hope Hospital
Country: UK

Publications

  1. ncbi request reprint Management of the spectrum of hormone refractory prostate cancer
    Noel W Clarke
    Christie Hospital and Salford Royal Hospitals NHS Trusts, Manchester, UK
    Eur Urol 50:428-38; discussion 438-9. 2006
  2. doi request reprint FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladder
    Caryn Hughes
    Manchester Institute of Biotechnology, University of Manchester, Manchester, UK
    J Biophotonics 6:73-87. 2013
  3. doi request reprint Classification of fixed urological cells using Raman tweezers
    Tim J Harvey
    School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, UK
    J Biophotonics 2:47-69. 2009
  4. doi request reprint Investigating FTIR based histopathology for the diagnosis of prostate cancer
    Matthew J Baker
    Manchester Interdisciplinary Biocentre, Centre for Instrumentation and Analytical Science, School of Chemical Engineering and Analytical Science, The University of Manchester, 131 Princess Street, Manchester, UK
    J Biophotonics 2:104-13. 2009
  5. doi request reprint Measurement of elastic properties of prostate cancer cells using AFM
    Elsa Correia Faria
    School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, The University of Manchester, Manchester, UK
    Analyst 133:1498-500. 2008
  6. ncbi request reprint Discrimination of prostate cancer cells by reflection mode FTIR photoacoustic spectroscopy
    Tim J Harvey
    School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, UK
    Analyst 132:292-5. 2007
  7. ncbi request reprint Direct evidence of lipid translocation between adipocytes and prostate cancer cells with imaging FTIR microspectroscopy
    Ehsan Gazi
    ProMPT Genito Urinary Cancer Research Group, Paterson Institute for Cancer Research, The University of Manchester, Manchester, UK
    J Lipid Res 48:1846-56. 2007
  8. pmc Characterization of the Hoechst 33342 side population from normal and malignant human renal epithelial cells
    Sanjai K Addla
    Genito Urinary Cancer Research Group, School of Cancer and Imaging Sciences, Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester, UK
    Am J Physiol Renal Physiol 295:F680-7. 2008
  9. doi request reprint Whole organ cross-section chemical imaging using label-free mega-mosaic FTIR microscopy
    Paul Bassan
    Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK
    Analyst 138:7066-9. 2013
  10. doi request reprint FTIR microscopy of biological cells and tissue: data analysis using resonant Mie scattering (RMieS) EMSC algorithm
    Paul Bassan
    Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK
    Analyst 137:1370-7. 2012

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Management of the spectrum of hormone refractory prostate cancer
    Noel W Clarke
    Christie Hospital and Salford Royal Hospitals NHS Trusts, Manchester, UK
    Eur Urol 50:428-38; discussion 438-9. 2006
    ..Aim of this review was to critically evaluate the current and potential approaches to patients affected by HRPC...
  2. doi request reprint FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladder
    Caryn Hughes
    Manchester Institute of Biotechnology, University of Manchester, Manchester, UK
    J Biophotonics 6:73-87. 2013
    ..As shown, their spectroscopic signals can change dramatically as a consequence of differentiation. Example cases are discussed and compared with histological evaluations...
  3. doi request reprint Classification of fixed urological cells using Raman tweezers
    Tim J Harvey
    School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, UK
    J Biophotonics 2:47-69. 2009
    ..Results indicate that urine has no detrimental effect on prediction results...
  4. doi request reprint Investigating FTIR based histopathology for the diagnosis of prostate cancer
    Matthew J Baker
    Manchester Interdisciplinary Biocentre, Centre for Instrumentation and Analytical Science, School of Chemical Engineering and Analytical Science, The University of Manchester, 131 Princess Street, Manchester, UK
    J Biophotonics 2:104-13. 2009
    ..In this paper we report the results of a large patient study in which FTIR has been proven to grade CaP tissue specimens to a high degree of sensitivity and specificity...
  5. doi request reprint Measurement of elastic properties of prostate cancer cells using AFM
    Elsa Correia Faria
    School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, The University of Manchester, Manchester, UK
    Analyst 133:1498-500. 2008
    ....
  6. ncbi request reprint Discrimination of prostate cancer cells by reflection mode FTIR photoacoustic spectroscopy
    Tim J Harvey
    School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, UK
    Analyst 132:292-5. 2007
    ....
  7. ncbi request reprint Direct evidence of lipid translocation between adipocytes and prostate cancer cells with imaging FTIR microspectroscopy
    Ehsan Gazi
    ProMPT Genito Urinary Cancer Research Group, Paterson Institute for Cancer Research, The University of Manchester, Manchester, UK
    J Lipid Res 48:1846-56. 2007
    ....
  8. pmc Characterization of the Hoechst 33342 side population from normal and malignant human renal epithelial cells
    Sanjai K Addla
    Genito Urinary Cancer Research Group, School of Cancer and Imaging Sciences, Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester, UK
    Am J Physiol Renal Physiol 295:F680-7. 2008
    ..The population is, however, heterogeneous, confirming that the terms "SP cell" and "stem cell" cannot be used interchangeably...
  9. doi request reprint Whole organ cross-section chemical imaging using label-free mega-mosaic FTIR microscopy
    Paul Bassan
    Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK
    Analyst 138:7066-9. 2013
    ..5 × 5.5 μm(2) of tissue and contains a full infrared spectrum providing a chemical fingerprint. The data acquisition time was 14 hours, thus showing that a clinical time frame of hours rather than days has been achieved. ..
  10. doi request reprint FTIR microscopy of biological cells and tissue: data analysis using resonant Mie scattering (RMieS) EMSC algorithm
    Paul Bassan
    Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK
    Analyst 137:1370-7. 2012
    ..Importantly however, we show that using three different non-ideal reference spectra, the same unique correction solution can be obtained...
  11. pmc Molecular mechanisms of metastasis in prostate cancer
    Noel W Clarke
    Genito Urinary Cancer Research Group, School of Cancer and Imaging Sciences, Paterson Institute for Cancer Research, Christie Hospital, University of Manchester, Manchester, UK
    Asian J Androl 11:57-67. 2009
    ..In this review, we present the current understanding of the molecular processes driving PCa metastasis to the bone...
  12. ncbi request reprint A correlation of FTIR spectra derived from prostate cancer biopsies with gleason grade and tumour stage
    Ehsan Gazi
    School of Chemical Engineering and Analytical Science, University of Manchester, Manchester, UK
    Eur Urol 50:750-60; discussion 760-1. 2006
    ..For the first time, we correlate FTIR spectra derived from prostate cancer (pCA) tissue with Gleason score and the clinical stage of the tumour at time of biopsy...
  13. ncbi request reprint Characterization of benign and malignant prostate epithelial Hoechst 33342 side populations
    Mick D Brown
    ProMPT Genito Urinary Cancer Research Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK
    Prostate 67:1384-96. 2007
    ..The prostate epithelial stem cell has been proposed as the primary origin of neoplastic change in prostate cancer. However, the isolation and characterization of unexpanded prostate epithelial stem cells have proven problematic...
  14. ncbi request reprint Assessing the challenges of Fourier transform infrared spectroscopic analysis of blood serum
    Caryn Hughes
    Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK Genito Urinary Cancer Research Group, Institute of Cancer Sciences, Paterson Building, The University of Manchester, Manchester Academic Health Science Centre, the Christie NHS Foundation Trust, Manchester, M20 4BX, UK
    J Biophotonics 7:180-8. 2014
    ..We review the possibilities of using different sample preparation methods and speculate upon the potential pitfalls of both transmission and attenuated total reflectance (ATR) techniques...
  15. doi request reprint Early prostate cancer--which treatment do men prefer and why?
    Carmel N Anandadas
    Department of Clinical Oncology, the Christie NHS Foundation Trust, Manchester, UK
    BJU Int 107:1762-8. 2011
    ..Preference (prospective cohort)...
  16. ncbi request reprint Differential inhibition of invasion and proliferation by bisphosphonates: anti-metastatic potential of Zoledronic acid in prostate cancer
    Richard Montague
    Genito Urinary Cancer Research Group, Kay Kendall Laboratory, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Wilmslow Road, Manchester, M20 4BX, UK
    Eur Urol 46:389-401; discussion 401-2. 2004
    ..To determine the mode of action of Zoledronic acid in the inhibition of metastasis in prostate cancer and the reduction of prostate cancer bone metastases...
  17. ncbi request reprint The molecular staging of prostate cancer
    Iain G McIntyre
    Genito Urinary Cancer Research Group, Christie Hospital, Manchester, UK
    BJU Int 94:1217-20. 2004
  18. doi request reprint Landmarks in non-hormonal pharmacological therapies for castration-resistant prostate cancer
    Noel W Clarke
    The Christie and Salford Royal Hospitals, Manchester, UK
    BJU Int 110:14-22. 2012
    ..Most of these remain experimental but on-going pharmacological development will inevitably provide urologists and urological oncologists with a broader range of therapeutic options for better cancer management in the future...
  19. ncbi request reprint The increased rate of prostate specific antigen testing has not affected prostate cancer presentation in an inner city population in the UK
    Moeketsi Mokete
    Department of Urology, Hope Hospital, Salford Royal Hospitals NHS Trust, Salford, Manchester, UK
    BJU Int 97:266-9. 2006
    ....
  20. doi request reprint A contemporary standard for morbidity and outcome after radical cystectomy
    Vijay A C Ramani
    Department of Urology, the Christie NHS Foundation Trust, Manchester, UK
    BJU Int 104:628-32. 2009
    ....
  21. ncbi request reprint Chemotherapy in hormone refractory prostate cancer: where do we stand?
    Noel W Clarke
    Eur Urol 46:709-11. 2004
  22. ncbi request reprint The origin of the bone scan as a tumour marker in prostate cancer
    Noel W Clarke
    Eur Urol 50:873-8. 2006
  23. pmc Early hormonal data from a multicentre phase II trial using transdermal oestrogen patches as first-line hormonal therapy in patients with locally advanced or metastatic prostate cancer
    Ruth E Langley
    Endocrinology and Metabolic Medicine, Imperial College, London, UK
    BJU Int 102:442-5. 2008
    ..To assess the hormonal effects of Fem7 (Merck, KGaA, Darmstadt, Germany) 100 microg transdermal oestrogen patches on men undergoing first-line androgen-deprivation therapy for prostate cancer...
  24. ncbi request reprint The natural history of postoperative renal function in patients undergoing ileal conduit diversion for cancer measured using serial isotopic glomerular filtration rate and 99m technetium-mercaptoacetyltriglycine renography
    Joanne D Samuel
    Departments of Urology, Christie Hospital, Salford, United Kingdom
    J Urol 176:2518-22; discussion 2522. 2006
    ....
  25. ncbi request reprint Radiotherapy and androgen deprivation in combination after local surgery (RADICALS): a new Medical Research Council/National Cancer Institute of Canada phase III trial of adjuvant treatment after radical prostatectomy
    Chris Parker
    Academic Unit of Radiotherapy and Oncology, Institute of Cancer Research and the Royal, Marsden NHS Foundation Trust, Sutton, Surrey, UK
    BJU Int 99:1376-9. 2007
  26. ncbi request reprint The influence of lipid metabolism on prostate cancer development and progression: is it time for a closer look?
    Noel W Clarke
    Eur Urol 52:3-4. 2007
  27. ncbi request reprint Optical artefacts in transflection mode FTIR microspectroscopic images of single cells on a biological support: the effect of back-scattering into collection optics
    Joe Lee
    School of Chemistry, University of Manchester, P O Box 88, Manchester, UK M60 1QD
    Analyst 132:750-5. 2007
    ..This leads to an apparent reduction in absorption at the cell...
  28. doi request reprint Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry
    Matthew J Baker
    Manchester Interdisciplinary Biocentre, Centre for Instrumentation and Analytical Science, School of Chemical Engineering and Analytical Science, The University of Manchester, UK
    Analyst 133:175-9. 2008
    ....