Richard Pebody

Summary

Affiliation: Health Protection Agency
Country: UK

Publications

  1. pmc A new sentinel surveillance system for severe influenza in England shows a shift in age distribution of hospitalised cases in the post-pandemic period
    Shelly Bolotin
    Health Protection Agency, London, United Kingdom
    PLoS ONE 7:e30279. 2012
  2. ncbi request reprint The United Kingdom public health response to an imported laboratory confirmed case of a novel coronavirus in September 2012
    R G Pebody
    Health Protection Agency HPA, London, UK
    Euro Surveill 17:20292. 2012
  3. pmc Rapid estimation of excess mortality: nowcasting during the heatwave alert in England and Wales in June 2011
    Helen K Green
    Department of Respiratory Diseases, Health Protection Agency, London, UK
    J Epidemiol Community Health 66:866-8. 2012
  4. doi request reprint Use of antibiotics and risk factors for carriage of Streptococcus pneumoniae: a longitudinal household study in the United Kingdom
    R G Pebody
    Centre for Infections, Health Protection Agency, London, UK
    Epidemiol Infect 137:555-61. 2009
  5. pmc Uptake of pneumococcal polysaccharide vaccine in at-risk populations in England and Wales 1999-2005
    R G Pebody
    HPA Centre for Infections, London, UK
    Epidemiol Infect 136:360-9. 2008
  6. doi request reprint No effect of 2008/09 seasonal influenza vaccination on the risk of pandemic H1N1 2009 influenza infection in England
    Richard Pebody
    Health Protection Agency Centre for Infections, 61 Colindale Avenue, UK
    Vaccine 29:2613-8. 2011
  7. pmc Use of antiviral drugs to reduce household transmission of pandemic (H1N1) 2009, United Kingdom
    Richard G Pebody
    Health Protection Agency, London, UK
    Emerg Infect Dis 17:990-9. 2011
  8. pmc The seroepidemiology of Bordetella pertussis infection in Western Europe
    R G Pebody
    Immunisation Department, Health Protection Agency HPA Communicable Disease Surveillance Centre, London, UK
    Epidemiol Infect 133:159-71. 2005
  9. ncbi request reprint Morbidity and mortality of pneumococcal meningitis and serotypes of causative strains prior to introduction of the 7-valent conjugant pneumococcal vaccine in England
    Alan P Johnson
    Department of Healthcare Associated Infection and Antimicrobial Resistance, Health Protection Agency Centre for Infections, London, NW9 5EQ, UK
    J Infect 55:394-9. 2007
  10. ncbi request reprint Trends in penicillin and macrolide resistance among pneumococci in the UK and the Republic of Ireland in relation to antibiotic sales to pharmacies and dispensing doctors
    David M Livermore
    Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5HT, UK
    Int J Antimicrob Agents 28:273-9. 2006

Detail Information

Publications42

  1. pmc A new sentinel surveillance system for severe influenza in England shows a shift in age distribution of hospitalised cases in the post-pandemic period
    Shelly Bolotin
    Health Protection Agency, London, United Kingdom
    PLoS ONE 7:e30279. 2012
    ..This article presents the results of the first season of operation of USISS in 2010/11...
  2. ncbi request reprint The United Kingdom public health response to an imported laboratory confirmed case of a novel coronavirus in September 2012
    R G Pebody
    Health Protection Agency HPA, London, UK
    Euro Surveill 17:20292. 2012
    ..Ten days after last exposure, none of 64 close contacts had developed severe disease, with 13 of 64 reporting mild respiratory symptoms. The novel coronavirus was not detected in 10 of 10 symptomatic contacts tested...
  3. pmc Rapid estimation of excess mortality: nowcasting during the heatwave alert in England and Wales in June 2011
    Helen K Green
    Department of Respiratory Diseases, Health Protection Agency, London, UK
    J Epidemiol Community Health 66:866-8. 2012
    ....
  4. doi request reprint Use of antibiotics and risk factors for carriage of Streptococcus pneumoniae: a longitudinal household study in the United Kingdom
    R G Pebody
    Centre for Infections, Health Protection Agency, London, UK
    Epidemiol Infect 137:555-61. 2009
    ..52, 95% CI 1.41-4.52). Taking antibiotics significantly reduces the risk of carriage the following month in a setting with a low prevalence of pneumococcal antimicrobial resistance...
  5. pmc Uptake of pneumococcal polysaccharide vaccine in at-risk populations in England and Wales 1999-2005
    R G Pebody
    HPA Centre for Infections, London, UK
    Epidemiol Infect 136:360-9. 2008
    ..In conclusion, there remain large gaps in the uptake of PPV in several high-risk populations in the United Kingdom. Effective strategies need to be developed to address these deficiencies...
  6. doi request reprint No effect of 2008/09 seasonal influenza vaccination on the risk of pandemic H1N1 2009 influenza infection in England
    Richard Pebody
    Health Protection Agency Centre for Infections, 61 Colindale Avenue, UK
    Vaccine 29:2613-8. 2011
    ..Vaccine effectiveness did not differ significantly by age-group or hospitalisation status. There was no evidence prior vaccination with TIV significantly altered subsequent risk of pandemic influenza H1N1 2009 infection...
  7. pmc Use of antiviral drugs to reduce household transmission of pandemic (H1N1) 2009, United Kingdom
    Richard G Pebody
    Health Protection Agency, London, UK
    Emerg Infect Dis 17:990-9. 2011
    ..9% (1/34) when the primary contact was a man (p = 0.010). Of 53 confirmed secondary case-patients, 45 had not received AV prophylaxis. The effectiveness of AV prophylaxis in preventing infection was 92%...
  8. pmc The seroepidemiology of Bordetella pertussis infection in Western Europe
    R G Pebody
    Immunisation Department, Health Protection Agency HPA Communicable Disease Surveillance Centre, London, UK
    Epidemiol Infect 133:159-71. 2005
    ....
  9. ncbi request reprint Morbidity and mortality of pneumococcal meningitis and serotypes of causative strains prior to introduction of the 7-valent conjugant pneumococcal vaccine in England
    Alan P Johnson
    Department of Healthcare Associated Infection and Antimicrobial Resistance, Health Protection Agency Centre for Infections, London, NW9 5EQ, UK
    J Infect 55:394-9. 2007
    ....
  10. ncbi request reprint Trends in penicillin and macrolide resistance among pneumococci in the UK and the Republic of Ireland in relation to antibiotic sales to pharmacies and dispensing doctors
    David M Livermore
    Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5HT, UK
    Int J Antimicrob Agents 28:273-9. 2006
    ..Stabilisation or decline in penicillin resistance has occurred in Ireland despite stable or increasing oral beta-lactam sales...
  11. pmc Seroprevalence of influenza A(H1N1)pdm09 virus antibody, England, 2010 and 2011
    Katja Hoschler
    Respiratory Virus Unit, Virus Reference Department, Microbiology Services Colindale, Health Protection Agency, 61 Colindale Ave, London, NW9 5HT, UK
    Emerg Infect Dis 18:1894-7. 2012
    ..Population-based seroepidemiology confirms that the third wave of influenza A(H1N1)pdm09 virus circulation was associated with a shift in age groups affected, with the highest rate of infection in young adults...
  12. doi request reprint Effective management in clusters of pneumococcal disease: a systematic review
    Marina Basarab
    Health Protection Agency, Centre for Infections, London, UK
    Lancet Infect Dis 11:119-30. 2011
    ....
  13. pmc Seroepidemiologic study of pandemic (H1N1) 2009 during outbreak in boarding school, England
    Sandra Johnson
    Health Protection Agency, London, UK
    Emerg Infect Dis 17:1670-7. 2011
    ..2%-43.0%) had negative test results, respectively. A weak association was found between seropositivity and a prophylactic dose of antiviral agents (AOR 0.55, 95% CI 0.30-0.99); prophylactic antiviral agents lowered the odds of ARI by 50%...
  14. pmc Trends in incidence of pneumococcal disease before introduction of conjugate vaccine: South West England, 1996-2005
    C A Ihekweazu
    Health Protection Agency, South West, Stonehouse, Stroud, Gloucestershire, UK
    Epidemiol Infect 136:1096-102. 2008
    ..This study provides an important baseline to assess the impact of changing vaccination programmes on the epidemiology of IPD, thus informing future use of pneumococcal vaccines...
  15. doi request reprint Effectiveness of trivalent and pandemic influenza vaccines in England and Wales 2008-2010: results from a cohort study in general practice
    Pia Hardelid
    Statistics Unit, Health Protection Agency Centre for Infections, London, UK
    Vaccine 30:1371-8. 2012
    ..The cohort study design could be used each season to estimate VE; however, residual confounding by indication could still present issues, despite adjustment for propensity to consult...
  16. pmc Deaths from norovirus among the elderly, England and Wales
    John P Harris
    Centre for Infections, GEZI, Health Protection Agency, London, UK
    Emerg Infect Dis 14:1546-52. 2008
    ..5%-18.5%) of deaths caused by noninfectious intestinal disease were associated with norovirus. An estimated 80 deaths each year in this age group may be associated with norovirus infection...
  17. pmc Mortality attributable to influenza in England and Wales prior to, during and after the 2009 pandemic
    Helen K Green
    Respiratory Diseases Department, Centre for Infectious Disease Surveillance and Control, Public Health England, London, United Kingdom
    PLoS ONE 8:e79360. 2013
    ..This analysis forms part of the preparatory work to establish a routine mortality monitoring system ahead of introduction of the UK universal childhood seasonal influenza vaccination programme in 2013/14. ..
  18. doi request reprint Effectiveness of seasonal influenza vaccine in preventing medically attended influenza infection in England and Wales during the 2010/2011 season: a primary care-based cohort study
    George Kafatos
    Statistics Unit, Public Health England, London, UK
    Influenza Other Respir Viruses 7:1175-80. 2013
    ..Estimates of seasonal influenza vaccine effectiveness (VE) are affected by factors such as the strain of the current circulating influenza virus and characteristics of the host...
  19. doi request reprint Has estimation of numbers of cases of pandemic influenza H1N1 in England in 2009 provided a useful measure of the occurrence of disease?
    Barry Evans
    Health Protection Agency, Centre for Infections, London, UK
    Influenza Other Respir Viruses 5:e504-12. 2011
    ..An approach was developed to estimate the number of cases of influenza-like illness (ILI) occurring because of infection with pandemic influenza virus...
  20. ncbi request reprint Pneumococcal carriage in United Kingdom families: estimating serotype-specific transmission parameters from longitudinal data
    Alessia Melegaro
    Modelling and Economics Unit, Centre for Infections, Health Protection Agency, London, United Kingdom
    Am J Epidemiol 166:228-35. 2007
    ..Only small differences in the transmission characteristics were found when vaccine and nonvaccine serotypes were grouped, suggesting that a serotype-specific analysis is needed to detect distinctive serotype behavior...
  21. doi request reprint Outbreaks of serious pneumococcal disease in closed settings in the post-antibiotic era: a systematic review
    Chikwe Ihekweazu
    Health Protection Agency, Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK
    J Infect 61:21-7. 2010
    ..Our objective was to review the epidemiology of reported outbreaks of serious pneumococcal disease in closed settings to inform the development of guidelines to manage such outbreaks...
  22. pmc A longitudinal household study of Streptococcus pneumoniae nasopharyngeal carriage in a UK setting
    M Hussain
    Immunisation Department, Communicable Disease Surveillance Centre, Health Protection Agency Centre for Infections, London, UK
    Epidemiol Infect 133:891-8. 2005
    ..pneumoniae is common in a UK setting in the pre-conjugate vaccine era. PCV would protect against a large proportion of carriage isolates. However, the impact of vaccination on non-vaccine serotypes will need to be monitored...
  23. doi request reprint The burden of infection with cytomegalovirus in England and Wales: how many women are infected in pregnancy?
    A J Vyse
    Health Protection Agency, Centre for Infections, Immunisation Department, London, UK
    Epidemiol Infect 137:526-33. 2009
    ....
  24. doi request reprint A comparison of hepatitis B seroepidemiology in ten European countries
    A Nardone
    Centre for Infections, Health Protection Agency, London, UK
    Epidemiol Infect 137:961-9. 2009
    ..Regular serological surveys to ascertain HBV status within a population, such as reported here, provide important data to assess the need for and to evaluate universal HBV vaccination programmes...
  25. ncbi request reprint Sero-epidemiology of Bordetella pertussis in England and Wales
    A Nardone
    Immunisation Division, Communicable Disease Surveillance Centre, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    Vaccine 22:1314-9. 2004
    ..There is an important incidence of infection in the population, which is greater amongst children than adults, but there is only limited evidence of a correlation with epidemic cycles...
  26. pmc Sero-epidemiology of mumps in western Europe
    A Nardone
    PHLS Communicable Disease Surveillance Centre, 61 Colindale Avenue, London, NW9 SEQ, UK
    Epidemiol Infect 131:691-701. 2003
    ..Sero-surveillance of mumps is an important component of disease control and its usefulness will be enhanced by the development of an international mumps standard...
  27. ncbi request reprint Estimating the number of deaths with rotavirus as a cause in England and wales
    Mark Jit
    Modelling and Economics Unit, Immunisation Department, Health Protection Agency, London, UK
    Hum Vaccin 3:23-6. 2007
    ..The two methods gave estimates of 3.8 and 3.2 rotavirus deaths a year respectively...
  28. doi request reprint International flight-related transmission of pandemic influenza A(H1N1)pdm09: an historical cohort study of the first identified cases in the United Kingdom
    Nicholas Young
    Health Protection Agency, Bristol, UK
    Influenza Other Respir Viruses 8:66-73. 2014
    ..Current World Health Organization (WHO) guidance recommends contact tracing of passengers seated within two rows of a case of influenza during air travel...
  29. doi request reprint Predictors of death after severe Streptococcus pyogenes infection
    Theresa L Lamagni
    Health Protection Agency Centre for Infections, London, UK
    Emerg Infect Dis 15:1304-7. 2009
    ..Some evidence suggested a seasonal pattern to patient survival rate...
  30. pmc Molecular typing of pneumococci for investigation of linked cases of invasive pneumococcal disease
    Bruno Pichon
    Respiratory and Systemic Infection Laboratory, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, United Kingdom
    J Clin Microbiol 48:1926-8. 2010
    ....
  31. doi request reprint Infection-related mortality in children with malignancy in England and Wales, 2003-2005
    Jessica Bate
    St George s University of London, Paediatric Infectious Diseases Unit, Cranmer Terrace, London, UK
    Pediatr Blood Cancer 53:371-4. 2009
    ..The aim of this study is to describe the infections contributing to deaths in children under 15 years with malignancy in England and Wales in the period 2003-2005...
  32. ncbi request reprint Immunogenicity of second dose measles-mumps-rubella (MMR) vaccine and implications for serosurveillance
    R G Pebody
    Sero Epidemiology Unit, Immunisation Division, PHLS Communicable Disease Surveillance Centre, 61 Colindale Avenue, London, UK
    Vaccine 20:1134-40. 2002
    ..Further studies including qualitative measures, such as avidity, in different populations are merited and may contribute to the understanding of MMR population protection...
  33. pmc The sero-epidemiology of diphtheria in Western Europe. ESEN Project. European Sero-Epidemiology Network
    W J Edmunds
    PHLS Communicable Disease Surveillance Centre, London, UK
    Epidemiol Infect 125:113-25. 2000
    ..Although the United Kingdom and Sweden both have higher proportions of seronegative children than elsewhere the likelihood of a resurgence of diphtheria in these countries seems remote...
  34. pmc Lack of serologic evidence of Neospora caninum in humans, England
    Catherine M McCann
    University of Liverpool, Liverpool, UK Health Protection Agency, London, UK
    Emerg Infect Dis 14:978-80. 2008
    ..Results were obtained by using immunofluorescence antibody testing and ELISA to analyze frequency distribution...
  35. pmc The seroepidemiology of herpes simplex virus type 1 and 2 in Europe
    R G Pebody
    Immunisation Department, Communicable Disease Surveillance Centre, London, UK
    Sex Transm Infect 80:185-91. 2004
    ..To describe the seroepidemiology of herpes simplex virus (HSV) types 1 and 2 in the general populations of eight European countries to better understand recent reported changes in disease epidemiology...
  36. ncbi request reprint Pneumococcal disease surveillance in Europe
    R G Pebody
    Health Protection Agency, London, United Kingdom
    Euro Surveill 11:171-8. 2006
    ..If IPD surveillance in Europe can be strengthened, countries will be able to make informed decisions regarding the introduction of new pneumococcal vaccines and also to monitor and compare the impact and effectiveness of new programmes...
  37. doi request reprint Pandemic (H1N1) 2009 influenza in the UK: clinical and epidemiological findings from the first few hundred (FF100) cases
    E McLean
    Health Protection Agency, Centre for Infections, London, UK
    Epidemiol Infect 138:1531-41. 2010
    ..9 days, P=0.01). No patients died, although 14 were hospitalized, of whom three required mechanical ventilation. The FF100 identified key clinical and epidemiological characteristics of infection with this novel virus in near real-time...
  38. doi request reprint Estimated mortality and hospital admission due to rotavirus infection in the WHO European region
    C J Williams
    Health Protection Agency Centre for Infections, London, UK
    Epidemiol Infect 137:607-16. 2009
    ..Data from low-income countries is still sparse, and improved disease burden studies are required to better inform regional vaccine policy...
  39. ncbi request reprint Pneumococcal vaccination policy in Europe
    R G Pebody
    Health Protection Agency Centre, London, United Kingdom
    Euro Surveill 10:174-8. 2005
    ..Indeed, at least one country, Luxembourg, has since implemented a universal infant PCV immunisation policy...
  40. pmc The seroepidemiology of measles in Western Europe
    H de Melker
    National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Epidemiol Infect 126:249-59. 2001
    ..In the high susceptibility country the priority will be to increase infant vaccine coverage and reduce regional variation in coverage levels...
  41. ncbi request reprint Universal varicella-zoster vaccination: is Europe ready?
    R G Pebody
    Int J Clin Pract 59:1248-50. 2005
  42. ncbi request reprint QFLU: new influenza monitoring in UK primary care to support pandemic influenza planning
    J Hippisley-Cox
    University of Nottingham, Nottingham, United Kingdom
    Euro Surveill 11:E060622.4. 2006