C A Ison

Summary

Affiliation: Health Protection Agency
Country: UK

Publications

  1. doi request reprint Antimicrobial resistance in sexually transmitted infections in the developed world: implications for rational treatment
    Catherine A Ison
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency, London, UK
    Curr Opin Infect Dis 25:73-8. 2012
  2. doi request reprint Evolution of Neisseria gonorrhoeae is a continuing challenge for molecular detection of gonorrhoea: false negative gonococcal porA mutants are spreading internationally
    Catherine A Ison
    Sexually Transmitted Bacteria Reference Unit, Health Protection Agency, 61 Colindale Avenue, Colindale, London NW9 5HT, UK
    Sex Transm Infect 89:197-201. 2013
  3. ncbi request reprint Comparability of laboratory diagnosis and antimicrobial susceptibility testing of Neisseria gonorrhoeae from reference laboratories in Western Europe
    C A Ison
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency Centre for Infections, London, UK
    J Antimicrob Chemother 58:580-6. 2006
  4. doi request reprint Antimicrobial resistance in Neisseria gonorrhoeae in the UK: surveillance and management
    Catherine A Ison
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency, 61 Colindale Avenue, London, UK
    Expert Rev Anti Infect Ther 9:867-76. 2011
  5. pmc Update on lymphogranuloma venereum in the United Kingdom
    Heather Jebbari
    Health Protection Agency, Centre for Infections, London, UK
    Sex Transm Infect 83:324-6. 2007
  6. pmc Which cephalosporin for gonorrhoea?
    C A Ison
    Sexually Transmitted Bacteria Reference Laboratory, Specialist and Reference Microbiology Division, Health Protection Agency, 61 Colindale Avenue, London NW9 5HT, UK
    Sex Transm Infect 80:386-8. 2004
  7. doi request reprint Molecular epidemiology of syphilis in Scotland
    M J Cole
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency, London NW9 5EQ, UK
    Sex Transm Infect 85:447-51. 2009
  8. doi request reprint Emergence of high-level azithromycin resistance in Neisseria gonorrhoeae in England and Wales
    S A Chisholm
    Sexually Transmitted Bacteria Reference Laboratory, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, Colindale, London NW9 5HT, UK
    J Antimicrob Chemother 64:353-8. 2009
  9. pmc The prevalence of lymphogranuloma venereum infection in men who have sex with men: results of a multicentre case finding study
    H Ward
    Imperial College London, London, UK
    Sex Transm Infect 85:173-5. 2009
  10. doi request reprint Epidemiology and clinical presentation of gonorrhoea in England and Wales: findings from the Gonococcal Resistance to Antimicrobials Surveillance Programme 2001-2006
    V Delpech
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency Centre for Infections, London NW9 5EQ, UK
    Sex Transm Infect 85:317-21. 2009

Collaborators

Detail Information

Publications32

  1. doi request reprint Antimicrobial resistance in sexually transmitted infections in the developed world: implications for rational treatment
    Catherine A Ison
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency, London, UK
    Curr Opin Infect Dis 25:73-8. 2012
    ..The scope of the problem and the implications for treatment that follow are discussed in this review...
  2. doi request reprint Evolution of Neisseria gonorrhoeae is a continuing challenge for molecular detection of gonorrhoea: false negative gonococcal porA mutants are spreading internationally
    Catherine A Ison
    Sexually Transmitted Bacteria Reference Unit, Health Protection Agency, 61 Colindale Avenue, Colindale, London NW9 5HT, UK
    Sex Transm Infect 89:197-201. 2013
    ..Here we describe the characterisation of two such gonococcal isolates received by the reference service at the Health Protection Agency, London, England...
  3. ncbi request reprint Comparability of laboratory diagnosis and antimicrobial susceptibility testing of Neisseria gonorrhoeae from reference laboratories in Western Europe
    C A Ison
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency Centre for Infections, London, UK
    J Antimicrob Chemother 58:580-6. 2006
    ..Surveillance of bacterial STIs is important across Europe because of the movement of individuals between countries at a time when STI incidence appears to be increasing in many countries...
  4. doi request reprint Antimicrobial resistance in Neisseria gonorrhoeae in the UK: surveillance and management
    Catherine A Ison
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency, 61 Colindale Avenue, London, UK
    Expert Rev Anti Infect Ther 9:867-76. 2011
    ..Innovative and collaborative approaches will be essential to maintain gonorrhea as a treatable infection...
  5. pmc Update on lymphogranuloma venereum in the United Kingdom
    Heather Jebbari
    Health Protection Agency, Centre for Infections, London, UK
    Sex Transm Infect 83:324-6. 2007
    ..This report updates the UK epidemiology of lymphogranuloma venereum (LGV) to the end of April 2007...
  6. pmc Which cephalosporin for gonorrhoea?
    C A Ison
    Sexually Transmitted Bacteria Reference Laboratory, Specialist and Reference Microbiology Division, Health Protection Agency, 61 Colindale Avenue, London NW9 5HT, UK
    Sex Transm Infect 80:386-8. 2004
    ..We therefore underscore that ceftriaxone or cefixime should be the agents of choice to replace ciprofloxacin, as recommended in the new treatment guidelines, and that cefuroxime is a poor substitute...
  7. doi request reprint Molecular epidemiology of syphilis in Scotland
    M J Cole
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency, London NW9 5EQ, UK
    Sex Transm Infect 85:447-51. 2009
    ..To examine the molecular epidemiology of syphilis in Scotland...
  8. doi request reprint Emergence of high-level azithromycin resistance in Neisseria gonorrhoeae in England and Wales
    S A Chisholm
    Sexually Transmitted Bacteria Reference Laboratory, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, Colindale, London NW9 5HT, UK
    J Antimicrob Chemother 64:353-8. 2009
    ..This study aimed to investigate the origin of high-level azithromycin resistance that emerged in isolates of Neisseria gonorrhoeae in England and Wales in 2007, and to establish methods for identifying high-level azithromycin resistance...
  9. pmc The prevalence of lymphogranuloma venereum infection in men who have sex with men: results of a multicentre case finding study
    H Ward
    Imperial College London, London, UK
    Sex Transm Infect 85:173-5. 2009
    ..To determine the prevalence of lymphogranuloma venereum (LGV) and non-LGV associated serovars of urethral and rectal Chlamydia trachomatis (CT) infection in men who have sex with men (MSM)...
  10. doi request reprint Epidemiology and clinical presentation of gonorrhoea in England and Wales: findings from the Gonococcal Resistance to Antimicrobials Surveillance Programme 2001-2006
    V Delpech
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency Centre for Infections, London NW9 5EQ, UK
    Sex Transm Infect 85:317-21. 2009
    ..To analyse the enhanced data for gonorrhoea cases in England and Wales collected by the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) to better inform health policy and targeted interventions...
  11. ncbi request reprint A prospective social and molecular investigation of gonococcal transmission
    H Ward
    Department of Epidemiology and Public Health, Imperial College School of Medicine, London, UK
    Lancet 356:1812-7. 2000
    ..Tracing chains of transmission is difficult, because sexual partners are commonly difficult or impossible to identify. We assess the use of gonococcal opa-typing in identifying transmission links not revealed through interview...
  12. ncbi request reprint European Surveillance of Sexually Transmitted Infections (ESSTI): the first combined antimicrobial susceptibility data for Neisseria gonorrhoeae in Western Europe
    I M C Martin
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency Centre for Infections, London, UK
    J Antimicrob Chemother 58:587-93. 2006
    ..To conduct a sentinel surveillance study for antimicrobial resistance in Neisseria gonorrhoeae in Western Europe in 2004 as part of the European Surveillance of Sexually Transmitted Infections (ESSTI) Programme...
  13. doi request reprint Presentation of clinically suspected persistent chlamydial infection: a case series
    R A Pitt
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    Int J STD AIDS 24:469-75. 2013
    ..There is a need for a case definition of clinical treatment failure, development of susceptibility testing methods and guidance on appropriate treatment for patients with persistent infection...
  14. pmc The prevalence of proline iminopeptidase negative Neisseria gonorrhoeae throughout England and Wales
    S Alexander
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency, Centre for Infections, Colindale Avenue, London NW9 5HT, UK
    Sex Transm Infect 82:280-2. 2006
    ..This study aimed to determine the frequency of Pip negative gonococci in England and Wales...
  15. doi request reprint Association of Mycoplasma genitalium with acute non-gonococcal urethritis in Russian men: a comparison with gonococcal and chlamydial urethritis
    D Taylor-Robinson
    Division of Medicine, Imperial College London, St Mary s Campus, Paddington, London, UK
    Int J STD AIDS 20:234-7. 2009
    ..genitalium. The data provide evidence for the pathogenicity and frequent occurrence of M. genitalium in men in Moscow and presumably elsewhere in Russia...
  16. pmc Gonorrhoea in London: usefulness of first line therapies
    C A Ison
    Department of Infectious Diseases and Microbiology, Faculty of Medicine, Imperial College of Science, Technology and Medicine, London, UK
    Sex Transm Infect 78:106-9. 2002
    ..To determine the true prevalence and patterns of resistance of Neisseria gonorrhoeae to antimicrobial agents used for therapy in London...
  17. pmc Gonorrhoea
    C Bignell
    Sexually Transmitted Bacteria Reference Laboratory, Health Protection Agency Centre for Infections, Colindale, London, UK
    Sex Transm Infect 82:iv6-9. 2006
  18. ncbi request reprint Results of a Europe-wide investigation to assess the presence of a new variant of Chlamydia trachomatis
    E J Savage
    ESSTI European Surveillance of STIs network, Health Protection Agency, London, UK
    Euro Surveill 12:E3-4. 2007
    ..It is too early to tell whether the variant will remain confined to Sweden or whether the number of cases will significantly increase. Enhanced surveillance will need to be continued to address these concerns...
  19. doi request reprint Audit of laboratory diagnostic methods for syphilis in England and Wales
    A K Amin
    Department of Medical Microbiology, Barts and The London NHS Trust, London, UK
    Sex Transm Infect 85:88-91. 2009
    ..A standard operating procedure for the serological diagnosis of syphilis has recently been developed by the Health Protection Agency. This study aimed to audit clinical and laboratory practice in England and Wales against this standard...
  20. pmc The epidemiology of ciprofloxacin resistant isolates of Neisseria gonorrhoeae in Scotland 2002: a comparison of phenotypic and genotypic analysis
    H M Palmer
    Scottish Neisseria gonorrhoeae Reference Laboratory, Department of Medical Microbiology, Royal Infirmary of Edinburgh, Edinburgh EH16 5SA, UK
    Sex Transm Infect 81:403-7. 2005
    ....
  21. pmc Persistence of two genotypes of Neisseria gonorrhoeae during transmission
    I M C Martin
    Department of Infectious Diseases and Microbiology, Faculty of Medicine, Imperial College London, London, United Kingdom
    J Clin Microbiol 41:5609-14. 2003
    ..gonorrhoeae. We propose that the level of diversity of opa genotypes in a population is linked to the degree of sexual mixing of individuals and the incidence of mixed infections of N. gonorrhoeae...
  22. ncbi request reprint Neisseria gonorrhoeae multi-antigen sequence typing (NG-MAST) of ciprofloxacin resistant isolates of Pretoria, South Africa
    M De Jongh
    Department of Microbiological Pathology, University of Limpopo, Medunsa Campus, Ga Rankuwa, Pretoria, South Africa
    J Clin Pathol 61:686-7. 2008
    ..There was one cluster (four isolates) of known sequence type (ST) similar to the pattern seen among strains from Scotland, England, and Durban, South Africa. Two other known STs were identified, while the remaining STs were unique...
  23. doi request reprint A real-time quadriplex PCR assay for the diagnosis of rectal lymphogranuloma venereum and non-lymphogranuloma venereum Chlamydia trachomatis infections
    C Y Chen
    Division of STD Prevention, National Center for HIV AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Mail Stop G 39, 1600 Clifton Road, Atlanta, GA 30333, USA
    Sex Transm Infect 84:273-6. 2008
    ..To develop and evaluate a real-time quadriplex PCR for the diagnosis of lymphogranuloma venereum (LGV) and non-LGV chlamydial infections using rectal swab specimens...
  24. pmc Lymphogranuloma venereum in the United Kingdom
    P French
    Sex Transm Infect 81:97-8. 2005
  25. pmc Introduction and summary tables
    J D C Ross
    Whittall Street Clinic, Whittall Street, Birmingham B4 6DH, UK
    Sex Transm Infect 82:iv1-5. 2006
  26. pmc Diagnosis of lymphogranuloma venereum from biopsy samples
    I M C Martin
    Gut 55:1522-3. 2006
  27. pmc Methods employed by genitourinary medicine clinics in the United Kingdom to diagnose bacterial vaginosis
    F E A Keane
    Department of Genitourinary Medicine, Royal Cornwall Hospital, Treliske, Truro TR1 3LJ, UK
    Sex Transm Infect 81:155-7. 2005
    ..To determine the methods used by genitourinary medicine (GUM) clinics in the United Kingdom for the diagnosis of bacterial vaginosis (BV)...
  28. pmc Detection of mixed infection of Neisseria gonorrhoeae
    I M C Martin
    Department of Infectious Diseases and Microbiology, Faculty of Medicine, Imperial College of Science Technology and Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Sex Transm Infect 79:56-8. 2003
    ..We report the first published evidence, to our knowledge, of the demonstration of the potential existence of mixed infections of Neisseria gonorrhoeae in vivo through the use of a highly discriminatory genotypic technique...
  29. pmc Gonococcal resistance to beta-lactams and tetracycline involves mutation in loop 3 of the porin encoded at the penB locus
    M J Gill
    Department of Infection, University of Birmingham Medical School, Birmingham, United Kingdom
    Antimicrob Agents Chemother 42:2799-803. 1998
    ....
  30. ncbi request reprint Naturally occurring isolates of Neisseria gonorrhoeae, which display anomalous serovar properties, express PIA/PIB hybrid porins, deletions in PIB or novel PIA molecules
    S J Cooke
    Molecular Microbiology Group, Southampton General Hospital, Southampton, UK
    FEMS Microbiol Lett 162:75-82. 1998
    ..This is the first demonstration of naturally occurring gonococci expressing a hybrid Protein IA/IB...
  31. ncbi request reprint Involvement of the gonococcal MtrE protein in the resistance of Neisseria gonorrhoeae to toxic hydrophobic agents
    R M Delahay
    Department of Medical Microbiology, Imperial College School of Medicine, St Mary s, London
    Microbiology 143:2127-33. 1997
    ..A transposon-like element, similar to that found downstream of the region containing the promoters for mtrR and mtrC in Neisseria meningitidis, was identified 63 bp downstream of the mtrE gene...
  32. ncbi request reprint Variation within serovars of Neisseria gonorrhoeae detected by structural analysis of outer-membrane protein PIB and by pulsed-field gel electrophoresis
    S J Cooke
    Molecular Microbiology Group, University of Southampton Medical School, Southampton General Hospital, UK
    Microbiology 143:1415-22. 1997
    ....