A J Buckton

Summary

Affiliation: Health Protection Agency
Country: UK

Publications

  1. pmc Multitypic hepatitis C virus infection identified by real-time nucleotide sequencing of minority genotypes
    Andrew J Buckton
    Centre for Infections, Health Protection Agency, 61 Colindale Avenue, Colindale, London NW9 5HT, United Kingdom
    J Clin Microbiol 44:2779-84. 2006
  2. ncbi Emergence of occult minority genotype 2b hepatitis C infection in an HIV-1-co-infected patient treated for genotype 5a HCV infection with 48 weeks of pegylated-interferon-alpha 2b and ribavirin
    A J Buckton
    Virus Reference Department, Centre for Infections, Health Protection Agency, London, UK
    J Clin Virol 40:60-3. 2007
  3. doi Development and optimization of an internally controlled dried blood spot assay for surveillance of human immunodeficiency virus type-1 drug resistance
    Andrew J Buckton
    Virus Reference Department, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    J Antimicrob Chemother 62:1191-8. 2008
  4. doi New methods for the surveillance of HIV drug resistance in the resource poor world
    Andrew J Buckton
    Centre for Infections, Health Protection Agency, London, UK
    Curr Opin Infect Dis 21:653-8. 2008
  5. doi HIV type-1 drug resistance in treatment-naive patients monitored using minority species assays: a systematic review and meta-analysis
    Andrew J Buckton
    Centre for Infections, Health Protection Agency, London, UK
    Antivir Ther 16:9-16. 2011
  6. doi Increased detection of the HIV-1 reverse transcriptase M184V mutation using mutation-specific minority assays in a UK surveillance study suggests evidence of unrecognized transmitted drug resistance
    A J Buckton
    Centre for Infections, Health Protection Agency, London, UK
    HIV Med 12:250-4. 2011
  7. pmc Evaluation of a new assay in comparison with reverse hybridization and sequencing methods for hepatitis C virus genotyping targeting both 5' noncoding and nonstructural 5b genomic regions
    Elisa Martro
    Microbiology Department, Hospital Universitari Germans Trias i Pujol, Ctra de Canyet, s n 08916 Badalona, Spain
    J Clin Microbiol 46:192-7. 2008

Collaborators

Detail Information

Publications7

  1. pmc Multitypic hepatitis C virus infection identified by real-time nucleotide sequencing of minority genotypes
    Andrew J Buckton
    Centre for Infections, Health Protection Agency, 61 Colindale Avenue, Colindale, London NW9 5HT, United Kingdom
    J Clin Microbiol 44:2779-84. 2006
    ..The low rate of detection in people at high risk of repeated HCV infection suggests that multitypic HCV carriage is uncommon...
  2. ncbi Emergence of occult minority genotype 2b hepatitis C infection in an HIV-1-co-infected patient treated for genotype 5a HCV infection with 48 weeks of pegylated-interferon-alpha 2b and ribavirin
    A J Buckton
    Virus Reference Department, Centre for Infections, Health Protection Agency, London, UK
    J Clin Virol 40:60-3. 2007
    ..Occult presence of minority HCV subpopulations and their acquisition of mutations following therapy can result in poor treatment outcome...
  3. doi Development and optimization of an internally controlled dried blood spot assay for surveillance of human immunodeficiency virus type-1 drug resistance
    Andrew J Buckton
    Virus Reference Department, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    J Antimicrob Chemother 62:1191-8. 2008
    ..We present the evaluation of a methodology for the genotypic assessment of human immunodeficiency virus type-1 (HIV-1) drug resistance, optimized for use with dried blood spots (DBS)...
  4. doi New methods for the surveillance of HIV drug resistance in the resource poor world
    Andrew J Buckton
    Centre for Infections, Health Protection Agency, London, UK
    Curr Opin Infect Dis 21:653-8. 2008
    ..This article reviews new surveillance methods and practices used to monitor drug resistance in the developing world...
  5. doi HIV type-1 drug resistance in treatment-naive patients monitored using minority species assays: a systematic review and meta-analysis
    Andrew J Buckton
    Centre for Infections, Health Protection Agency, London, UK
    Antivir Ther 16:9-16. 2011
    ..Because minority species assays are mutation-specific, the benefit of this approach differs depending on the mutation being detected...
  6. doi Increased detection of the HIV-1 reverse transcriptase M184V mutation using mutation-specific minority assays in a UK surveillance study suggests evidence of unrecognized transmitted drug resistance
    A J Buckton
    Centre for Infections, Health Protection Agency, London, UK
    HIV Med 12:250-4. 2011
    ..The aim of the study was to estimate the levels of transmitted drug resistance (TDR) in HIV-1 using very sensitive assays to detect minority drug-resistant populations...
  7. pmc Evaluation of a new assay in comparison with reverse hybridization and sequencing methods for hepatitis C virus genotyping targeting both 5' noncoding and nonstructural 5b genomic regions
    Elisa Martro
    Microbiology Department, Hospital Universitari Germans Trias i Pujol, Ctra de Canyet, s n 08916 Badalona, Spain
    J Clin Microbiol 46:192-7. 2008
    ....