Michael C Barber

Summary

Affiliation: Hannah Research Institute
Country: UK

Publications

  1. ncbi request reprint Growth hormone, acting in part through the insulin-like growth factor axis, rescues developmental, but not metabolic, activity in the mammary gland of mice expressing a single allele of the prolactin receptor
    Gordon J Allan
    Institut National de la Sante et de la Recherche Medicale, Unite 344, Faculte de Medecine Necker, 75730 Paris, France
    Endocrinology 143:4310-9. 2002
  2. ncbi request reprint Structure and regulation of acetyl-CoA carboxylase genes of metazoa
    Michael C Barber
    Hannah Research Institute, Ayr, KA6 5HL, Scotland, United Kingdom
    Biochim Biophys Acta 1733:1-28. 2005
  3. ncbi request reprint Characterisation of an N-terminal variant of acetyl-CoA carboxylase-alpha: expression in human tissues and evolutionary aspects
    Maureen T Travers
    Cell Biochemistry Group, Hannah Research Institute, Hannah Research Park, Ayr, Scotland KA6 5HL, UK
    Biochim Biophys Acta 1634:97-106. 2003
  4. ncbi request reprint Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland
    David J Flint
    Hannah Research Institute, Ayr KA6 5HL, UK
    Am J Physiol Endocrinol Metab 288:E1179-87. 2005
  5. pmc Induction of transcripts derived from promoter III of the acetyl-CoA carboxylase-alpha gene in mammary gland is associated with recruitment of SREBP-1 to a region of the proximal promoter defined by a DNase I hypersensitive site
    Michael C Barber
    Hannah Research Institute, Ayr KA6 5HL, Scotland, UK
    Biochem J 375:489-501. 2003
  6. ncbi request reprint Asymmetric expression of transcripts derived from the shared promoter between the divergently oriented ACACA and TADA2L genes
    Maureen T Travers
    Hannah Research Institute, Ayr KA6 5HL, UK
    Genomics 85:71-84. 2005
  7. ncbi request reprint Insulin-like growth factor binding protein-5 (IGFBP-5) induces premature cell death in the mammary glands of transgenic mice
    Elizabeth Tonner
    Hannah Research Institute, Ayr KA6 5HL, England, UK
    Development 129:4547-57. 2002
  8. ncbi request reprint Localization of messenger RNAs encoding enzymes associated with malonyl-CoA metabolism in mouse brain
    Annette Sorensen
    Hannah Research Institute, Ayr KA6 5HL, UK
    Brain Res Gene Expr Patterns 1:167-73. 2002

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Growth hormone, acting in part through the insulin-like growth factor axis, rescues developmental, but not metabolic, activity in the mammary gland of mice expressing a single allele of the prolactin receptor
    Gordon J Allan
    Institut National de la Sante et de la Recherche Medicale, Unite 344, Faculte de Medecine Necker, 75730 Paris, France
    Endocrinology 143:4310-9. 2002
    ..This may be due to the maintenance by GH/IGF-I of a proliferative, rather than a differentiative, phenotype...
  2. ncbi request reprint Structure and regulation of acetyl-CoA carboxylase genes of metazoa
    Michael C Barber
    Hannah Research Institute, Ayr, KA6 5HL, Scotland, United Kingdom
    Biochim Biophys Acta 1733:1-28. 2005
    ..This review focuses on the structure of ACC genes and the putative individual roles of their gene products in fatty acid metabolism, taking an evolutionary viewpoint provided by data in genome databases...
  3. ncbi request reprint Characterisation of an N-terminal variant of acetyl-CoA carboxylase-alpha: expression in human tissues and evolutionary aspects
    Maureen T Travers
    Cell Biochemistry Group, Hannah Research Institute, Hannah Research Park, Ayr, Scotland KA6 5HL, UK
    Biochim Biophys Acta 1634:97-106. 2003
    ....
  4. ncbi request reprint Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland
    David J Flint
    Hannah Research Institute, Ayr KA6 5HL, UK
    Am J Physiol Endocrinol Metab 288:E1179-87. 2005
    ..Obese animals also exhibited marked abnormalities in alveolar development of the mammary gland, which may partially explain the delay in differentiation evident during lactogenesis...
  5. pmc Induction of transcripts derived from promoter III of the acetyl-CoA carboxylase-alpha gene in mammary gland is associated with recruitment of SREBP-1 to a region of the proximal promoter defined by a DNase I hypersensitive site
    Michael C Barber
    Hannah Research Institute, Ayr KA6 5HL, Scotland, UK
    Biochem J 375:489-501. 2003
    ..SREBP-1 motifs are also present in the proximal region of PII, which is also induced in lactation. This indicates that SREBP-1 is a major developmental regulator of the programme of lipid synthesis de novo in the lactating mammary gland...
  6. ncbi request reprint Asymmetric expression of transcripts derived from the shared promoter between the divergently oriented ACACA and TADA2L genes
    Maureen T Travers
    Hannah Research Institute, Ayr KA6 5HL, UK
    Genomics 85:71-84. 2005
    ..Thus, regulation of clearance of Pol II from the promoter and the rate of elongation may therefore be determinants of the asymmetric expression of these transcripts...
  7. ncbi request reprint Insulin-like growth factor binding protein-5 (IGFBP-5) induces premature cell death in the mammary glands of transgenic mice
    Elizabeth Tonner
    Hannah Research Institute, Ayr KA6 5HL, England, UK
    Development 129:4547-57. 2002
    ..It clearly demonstrates that IGF-I is an important developmental/survival factor for the mammary gland and, furthermore, this cell death programme may be utilised in a wide variety of tissues...
  8. ncbi request reprint Localization of messenger RNAs encoding enzymes associated with malonyl-CoA metabolism in mouse brain
    Annette Sorensen
    Hannah Research Institute, Ayr KA6 5HL, UK
    Brain Res Gene Expr Patterns 1:167-73. 2002
    ..Localization of transcripts encoding enzymes involved in fatty acid synthesis and beta-oxidation in distinct nuclei of the hypothalamus supports a role for malonyl-CoA as a potential effector of satiety...