Christopher J Hammond

Summary

Country: UK

Publications

  1. ncbi A susceptibility locus for myopia in the normal population is linked to the PAX6 gene region on chromosome 11: a genomewide scan of dizygotic twins
    Christopher J Hammond
    Twin Research and Genetic Epidemiology Unit, St Thomas Hospital, London, and West Kent Eye Center, Princess Royal University Hospital, Orpington, United Kingdom
    Am J Hum Genet 75:294-304. 2004
  2. ncbi Repeated measures of intraocular pressure result in higher heritability and greater power in genetic linkage studies
    Francis Carbonaro
    Department of Twin Research and Genetic Epidemiology, King s College London School of Medicine, London, United Kingdom
    Invest Ophthalmol Vis Sci 50:5115-9. 2009
  3. ncbi Common polymorphisms in the SERPINI2 gene are associated with refractive error in the 1958 British Birth Cohort
    Pirro G Hysi
    MRC Centre of Epidemiology for Child Health, Institute of Child Health, University College London, London, United Kingdom
    Invest Ophthalmol Vis Sci 53:440-7. 2012
  4. ncbi Estimating heritability and shared environmental effects for refractive error in twin and family studies
    Margarida C Lopes
    Department of Twin Research and Genetic Epidemiology, King s College London School of Medicine, London, United Kingdom
    Invest Ophthalmol Vis Sci 50:126-31. 2009
  5. ncbi A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25
    Pirro G Hysi
    Department of Twin Research and Genetic Epidemiology, King s College London, St Thomas Hospital, London, UK
    Nat Genet 42:902-5. 2010
  6. ncbi Identification and replication of three novel myopia common susceptibility gene loci on chromosome 3q26 using linkage and linkage disequilibrium mapping
    Toby Andrew
    Twin Research and Genetic Epidemiology, King s College London, St Thomas Hospital, London, UK
    PLoS Genet 4:e1000220. 2008
  7. ncbi The relationship between retinal arteriolar and venular calibers is genetically mediated, and each is associated with risk of cardiovascular disease
    Samantha J Fahy
    Department of Twin Research and Genetic Epidemiology, King s College London, School of Medicine, London, United Kingdom
    Invest Ophthalmol Vis Sci 52:975-81. 2011
  8. ncbi The heritability of macular response to supplemental lutein and zeaxanthin: a classic twin study
    Christopher J Hammond
    Department of Twin Research and Genetic Epidemiology, King s College London, St Thomas Hospital Campus, London, United Kingdom
    Invest Ophthalmol Vis Sci 53:4963-8. 2012
  9. ncbi Genetic dissection of myopia: evidence for linkage of ocular axial length to chromosome 5q
    Gu Zhu
    Genetic Epidemiology Unit, Queensland Institute of Medical Research, Brisbane, Australia
    Ophthalmology 115:1053-1057.e2. 2008
  10. ncbi Novel mutations in the small leucine-rich repeat protein/proteoglycan (SLRP) genes in high myopia
    Marja Majava
    Collagen Research Unit, Biocenter and Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland
    Hum Mutat 28:336-44. 2007

Collaborators

Detail Information

Publications10

  1. ncbi A susceptibility locus for myopia in the normal population is linked to the PAX6 gene region on chromosome 11: a genomewide scan of dizygotic twins
    Christopher J Hammond
    Twin Research and Genetic Epidemiology Unit, St Thomas Hospital, London, and West Kent Eye Center, Princess Royal University Hospital, Orpington, United Kingdom
    Am J Hum Genet 75:294-304. 2004
    ....
  2. ncbi Repeated measures of intraocular pressure result in higher heritability and greater power in genetic linkage studies
    Francis Carbonaro
    Department of Twin Research and Genetic Epidemiology, King s College London School of Medicine, London, United Kingdom
    Invest Ophthalmol Vis Sci 50:5115-9. 2009
    ..This was a cohort study in which 344 pairs of twins, 163 monozygotic (MZ) and 181 dizygotic (DZ), were enrolled...
  3. ncbi Common polymorphisms in the SERPINI2 gene are associated with refractive error in the 1958 British Birth Cohort
    Pirro G Hysi
    MRC Centre of Epidemiology for Child Health, Institute of Child Health, University College London, London, United Kingdom
    Invest Ophthalmol Vis Sci 53:440-7. 2012
    ..To identify heritable genetic factors altering susceptibility to refractive error in the general population...
  4. ncbi Estimating heritability and shared environmental effects for refractive error in twin and family studies
    Margarida C Lopes
    Department of Twin Research and Genetic Epidemiology, King s College London School of Medicine, London, United Kingdom
    Invest Ophthalmol Vis Sci 50:126-31. 2009
    ..This large twin study aimed to explore the role of shared environment in refractive error...
  5. ncbi A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25
    Pirro G Hysi
    Department of Twin Research and Genetic Epidemiology, King s College London, St Thomas Hospital, London, UK
    Nat Genet 42:902-5. 2010
    ..001). The identification of a susceptibility locus for refractive error on 15q25 will be important in characterizing the molecular mechanism responsible for the most common cause of visual impairment...
  6. ncbi Identification and replication of three novel myopia common susceptibility gene loci on chromosome 3q26 using linkage and linkage disequilibrium mapping
    Toby Andrew
    Twin Research and Genetic Epidemiology, King s College London, St Thomas Hospital, London, UK
    PLoS Genet 4:e1000220. 2008
    ..That two mitochondrial regulatory processes in the retina are implicated in the aetiology of myopia is surprising and is likely to provide novel insight into the molecular genetic basis of common myopia...
  7. ncbi The relationship between retinal arteriolar and venular calibers is genetically mediated, and each is associated with risk of cardiovascular disease
    Samantha J Fahy
    Department of Twin Research and Genetic Epidemiology, King s College London, School of Medicine, London, United Kingdom
    Invest Ophthalmol Vis Sci 52:975-81. 2011
    ..59) between these two traits and to assess the shared and specific influence of established and novel cardiovascular disease risk factors on them...
  8. ncbi The heritability of macular response to supplemental lutein and zeaxanthin: a classic twin study
    Christopher J Hammond
    Department of Twin Research and Genetic Epidemiology, King s College London, St Thomas Hospital Campus, London, United Kingdom
    Invest Ophthalmol Vis Sci 53:4963-8. 2012
    ..This classic twin study was designed to determine the heritability of macular pigment (MP) augmentation in response to supplemental lutein (L) and zeaxanthin (Z)...
  9. ncbi Genetic dissection of myopia: evidence for linkage of ocular axial length to chromosome 5q
    Gu Zhu
    Genetic Epidemiology Unit, Queensland Institute of Medical Research, Brisbane, Australia
    Ophthalmology 115:1053-1057.e2. 2008
    ..To estimate heritability and locate quantitative trait loci influencing axial length...
  10. ncbi Novel mutations in the small leucine-rich repeat protein/proteoglycan (SLRP) genes in high myopia
    Marja Majava
    Collagen Research Unit, Biocenter and Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland
    Hum Mutat 28:336-44. 2007
    ..This study provides new insight into the genetics of high myopia, suggesting that sequence variations in the SLRP genes expressed in the eye may be among the genetic risk factors underlying the pathogenesis of high myopia...