Jeremy Sanderson

Summary

Affiliation: Guy's Hospital
Country: UK

Publications

  1. ncbi request reprint Genetic variation in myosin IXB is associated with ulcerative colitis
    Adriaan A van Bodegraven
    Department of Gastroenterology, VU University Medical Centre, Amsterdam, The Netherlands
    Gastroenterology 131:1768-74. 2006
  2. ncbi request reprint Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy?
    Jeremy Sanderson
    Departments of Purine Research and Gastroenterology, Guy s and St Thomas Hospitals, London SE1 7EH, UK
    Ann Clin Biochem 41:294-302. 2004
  3. ncbi request reprint Genetic determinants of the thiopurine methyltransferase intermediate activity phenotype in British Asians and Caucasians
    Anthony M Marinaki
    Purine Research and Department of Gastroenterology, Guy s and St Thomas Hospital, London SE1 9RT, UK
    Pharmacogenetics 13:97-105. 2003
  4. ncbi request reprint The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease
    Andrew P Cuthbert
    Division of Medical and Molecular Genetics, Guy s, King s, and St Thomas School of Medicine, London, England, United Kingdom
    Gastroenterology 122:867-74. 2002
  5. pmc Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
    Paul R Burton
    Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK
    Nat Genet 39:1329-37. 2007
  6. ncbi request reprint A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5
    Natalie J Prescott
    Department of Medical and Molecular Genetics, King s College London School of Medicine, Guy s Hospital, London, UK
    Gastroenterology 132:1665-71. 2007
  7. pmc IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease
    Mark Tremelling
    IBD Research Group, Addenbrooke s Hospital, University of Cambridge, Cambridge, England, UK
    Gastroenterology 132:1657-64. 2007
  8. ncbi request reprint Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British population
    Alexandra V Pearce
    Department of Medical and Molecular Genetics, King s College London School of Medicine, 8th Floor Guy s Tower, Guy s Hospital, London SE1 9RT, UK
    Int J Colorectal Dis 22:419-24. 2007
  9. ncbi request reprint Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: a case-control and meta-analysis study
    Clive M Onnie
    Department of Medical and Molecular Genetics, King s College London School of Medicine, Guy s Hospital, UK
    Inflamm Bowel Dis 12:263-71. 2006
  10. ncbi request reprint Mutation, selection, and evolution of the Crohn disease susceptibility gene CARD15
    Kathy King
    Department of Medical and Molecular Genetics, Guy s, King s and St Thomas School of Medicine, King s College London, London, United Kingdom
    Hum Mutat 27:44-54. 2006

Collaborators

  • Stefan Schreiber
  • Tariq Ahmad
  • N J Samani
  • A T Hattersley
  • P Burton
  • Lon R Cardon
  • Theodore Reich
  • Mark J Caulfield
  • Chris Wallace
  • A Compston
  • G Kirov
  • Mark-S Silverberg
  • Peter Donaldson
  • Ian R Jones
  • Anne C Barton
  • Clive M Onnie
  • Alastair Forbes
  • Christopher G Mathew
  • Sheila A Fisher
  • Cathryn M Lewis
  • Natalie J Prescott
  • Muddassar M Mirza
  • John Mansfield
  • Kathy King
  • Andrew P Cuthbert
  • Jochen Hampe
  • Peter Green
  • Mark Tremelling
  • Alexandra V Pearce
  • Reenal Pattni
  • Adriaan A van Bodegraven
  • Anthony M Marinaki
  • Jack Satsangi
  • Fraser Cummings
  • Elaine R Nimmo
  • Rhian Gwilliam
  • Andrew Keniry
  • Andre Franke
  • Miles Parkes
  • Carlo Berzuini
  • John C Mansfield
  • Derek Jewell
  • Panos Deloukas
  • Dianne Soars
  • Francesca Bredin
  • Hazel Drummond
  • Richard Bagnall
  • A Hilary Steinhart
  • Ronald K Linskens
  • David P Strachan
  • Mark J Daly
  • Vito Annese
  • Anna Latiano
  • Alienke J Monsuur
  • Reenal C Pattni
  • Karen A Hunt
  • Mohammed F Sheikh
  • Christine R Curley
  • Raymond J Playford
  • John D Rioux
  • Alain Bitton
  • David A van Heel
  • J Bart A Crusius
  • Roland G Roberts
  • Cisca Wijmenga
  • Emilia Escuredo
  • Andrew J S Macpherson
  • Antony C Wicks
  • John F Mayberry
  • Azhar Ansari
  • Lynette D Fairbanks
  • El Monsor Shobowale-Bakre
  • John A Duley
  • Monica Arenas
  • Zubair H Khan
  • Silvia Mascheretti
  • Peter J P Croucher

Detail Information

Publications12

  1. ncbi request reprint Genetic variation in myosin IXB is associated with ulcerative colitis
    Adriaan A van Bodegraven
    Department of Gastroenterology, VU University Medical Centre, Amsterdam, The Netherlands
    Gastroenterology 131:1768-74. 2006
    ..These findings suggested the current study investigating a possible further role for MYO9B variation in inflammatory bowel disease...
  2. ncbi request reprint Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy?
    Jeremy Sanderson
    Departments of Purine Research and Gastroenterology, Guy s and St Thomas Hospitals, London SE1 7EH, UK
    Ann Clin Biochem 41:294-302. 2004
    ..This article reviews literature on the role of TPMT measurement prior to treatment with thiopurines and provides some guidance to the use of TPMT as a guide to tailoring thiopurine therapy...
  3. ncbi request reprint Genetic determinants of the thiopurine methyltransferase intermediate activity phenotype in British Asians and Caucasians
    Anthony M Marinaki
    Purine Research and Department of Gastroenterology, Guy s and St Thomas Hospital, London SE1 9RT, UK
    Pharmacogenetics 13:97-105. 2003
    ..Here we present the allele frequencies of genetic modifiers of TPMT activity in a British Asian population, as well as the concordance between intermediate TPMT activity and ORF and VNTR genotypes in a predominantly Caucasian population...
  4. ncbi request reprint The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease
    Andrew P Cuthbert
    Division of Medical and Molecular Genetics, Guy s, King s, and St Thomas School of Medicine, London, England, United Kingdom
    Gastroenterology 122:867-74. 2002
    ....
  5. pmc Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
    Paul R Burton
    Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK
    Nat Genet 39:1329-37. 2007
    ....
  6. ncbi request reprint A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5
    Natalie J Prescott
    Department of Medical and Molecular Genetics, King s College London School of Medicine, Guy s Hospital, London, UK
    Gastroenterology 132:1665-71. 2007
    ..We investigated this association in independent U.K. cohorts of Crohn's disease and ulcerative colitis...
  7. pmc IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease
    Mark Tremelling
    IBD Research Group, Addenbrooke s Hospital, University of Cambridge, Cambridge, England, UK
    Gastroenterology 132:1657-64. 2007
    ..We tested for association between IL23R and IBD in a large independent UK panel to determine the size of the effect and explore subphenotype correlation and interaction with CARD15...
  8. ncbi request reprint Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British population
    Alexandra V Pearce
    Department of Medical and Molecular Genetics, King s College London School of Medicine, 8th Floor Guy s Tower, Guy s Hospital, London SE1 9RT, UK
    Int J Colorectal Dis 22:419-24. 2007
    ....
  9. ncbi request reprint Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: a case-control and meta-analysis study
    Clive M Onnie
    Department of Medical and Molecular Genetics, King s College London School of Medicine, Guy s Hospital, UK
    Inflamm Bowel Dis 12:263-71. 2006
    ....
  10. ncbi request reprint Mutation, selection, and evolution of the Crohn disease susceptibility gene CARD15
    Kathy King
    Department of Medical and Molecular Genetics, Guy s, King s and St Thomas School of Medicine, King s College London, London, United Kingdom
    Hum Mutat 27:44-54. 2006
    ..The strategy developed here may have general application to the assessment of mutation pathogenicity and genetic models in other complex disorders...
  11. pmc Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease
    Muddassar M Mirza
    Division of Medical and Molecular Genetics, Guy s, King s, and Thomas s School of Medicine, King s College London, Guy s Hospital, London, United Kingdom
    Am J Hum Genet 72:1018-22. 2003
    ..0019). These findings suggest that genetic variants at the 5q31 (IBD5) locus may hasten the onset of Crohn disease and cooperate with CARD15 in disease causation...
  12. ncbi request reprint Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's disease
    Clive M Onnie
    Division of Genetics and Molecular Medicine, King s College London School of Medicine, Guy s Hospital, London, UK
    Eur J Gastroenterol Hepatol 20:37-45. 2008
    ..We studied 630 well-characterized patients to clarify the genotype/phenotype relationship in CD...