Research Topics
Species | J A CutlerSummaryAffiliation: Guy's and St Thomas' NHS Foundation Trust Country: UK Publications
| Collaborators |
Detail Information
Publications
The significance of published polymorphisms in 14 cases of mild factor VII deficiencyJacqueline A Cutler
Centre for Haemostasis and Thrombosis Haemophilia Reference Centre, St Thomas Hospital, London, UK
Blood Coagul Fibrinolysis 16:91-5. 2005..This study highlights the significance of mild FVII deficiency, and examines the importance of seven previously published polymorphisms in such patients...
Molecular characterization of 11 novel mutations in patients with heterozygous and homozygous FV deficiencyJ A Cutler
Centre for Haemostasis and Thrombosis, St Thomas Hospital, London, UK
Haemophilia 16:937-42. 2010..The addition of a significant number of previously unidentified mutations to the public domain will contribute to the knowledge and understanding of the molecular pathology of this rare disorder...
A rapid and cost-effective method for analysis of three common genetic risk factors for thrombosisJ A Cutler
The Reference Centre for Haemostatic and Thrombotic Disorders, St Thomas Hospital, London, UK
Blood Coagul Fibrinolysis 12:33-6. 2001..This sensitive protocol obviates the need for endonuclease digestion and the associated gel running and documentation, and leads to a reduction in the recurrent costs of laboratory consumables...
The identification and classification of 41 novel mutations in the factor VIII gene (F8C)J A Cutler
The Haemophilia Reference Centre, Centre for Thrombosis and Haemostasis, St Thomas Hospital, Lambeth Palace Road, London, UK
Hum Mutat 19:274-8. 2002..Our findings support the view that the phenotypic result of a mutation in the FVIII gene correlates more with the position of the amino acid change within the 3D structure of the protein than with the actual nature of the alteration...
