F H Marshall

Summary

Affiliation: Gunnels Wood Road
Country: UK

Publications

  1. ncbi Heterodimerization of G-protein-coupled receptors in the CNS
    F H Marshall
    Molecular Pharmacology Department, GlaxoWellcome Research and Development, Stevenage, Hertfordshire, UK
    Curr Opin Pharmacol 1:40-4. 2001
  2. ncbi Heterodimerization is required for the formation of a functional GABA(B) receptor
    J H White
    Receptor Systems, Molecular Pharmacology Unit, GlaxoWellcome, Medicines Research Centre, Stevenage, Hertfordshire, UK
    Nature 396:679-82. 1998
  3. ncbi Calcium sensing properties of the GABA(B) receptor
    A Wise
    Receptor Systems, Molecular Pharmacology Unit, Glaxo Wellcome Medicines Research Centre, Stevenage, Hertfordshire, UK
    Neuropharmacology 38:1647-56. 1999
  4. ncbi The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx
    J H White
    Receptor Systems, Molecular Pharmacology Department, Glaxo Wellcome Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, United Kingdom
    Proc Natl Acad Sci U S A 97:13967-72. 2000
  5. ncbi Advances in the molecular understanding of GABA(B) receptors
    A Billinton
    Dept of Neurobiology, Babraham Institute, Babraham, Cambridge, UK, CB2 4AT
    Trends Neurosci 24:277-82. 2001

Collaborators

  • M J Main
  • J H White
  • A Wise
  • A Billinton
  • P C Emson
  • A Green
  • J P Bolam
  • A O Ige
  • W Y Chan
  • R A McIllhinney
  • F Ciruela
  • R Wilson
  • N Fraser
  • N J Fraser
  • P Emson
  • A A Barnes
  • S M Foord
  • G H Disney

Detail Information

Publications5

  1. ncbi Heterodimerization of G-protein-coupled receptors in the CNS
    F H Marshall
    Molecular Pharmacology Department, GlaxoWellcome Research and Development, Stevenage, Hertfordshire, UK
    Curr Opin Pharmacol 1:40-4. 2001
    ..Crosstalk at the level of the receptors might explain some of the known physiological interactions of these neurotransmitter systems and also provide new approaches for therapeutic intervention...
  2. ncbi Heterodimerization is required for the formation of a functional GABA(B) receptor
    J H White
    Receptor Systems, Molecular Pharmacology Unit, GlaxoWellcome, Medicines Research Centre, Stevenage, Hertfordshire, UK
    Nature 396:679-82. 1998
    ..These results indicate that, in vivo, functional brain GABA(B) receptors may be heterodimers composed of GABA(B)R1 and GABA(B)R2...
  3. ncbi Calcium sensing properties of the GABA(B) receptor
    A Wise
    Receptor Systems, Molecular Pharmacology Unit, Glaxo Wellcome Medicines Research Centre, Stevenage, Hertfordshire, UK
    Neuropharmacology 38:1647-56. 1999
    ..Calcium appears to act allosterically to enhance GABA responses at the GABA(B) receptor, however, unlike the Ca2+-sensing receptor and some of the mGluR family, Ca2+ does not act as a ligand in its own right...
  4. ncbi The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx
    J H White
    Receptor Systems, Molecular Pharmacology Department, Glaxo Wellcome Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, United Kingdom
    Proc Natl Acad Sci U S A 97:13967-72. 2000
    ..Such a signaling mechanism is unique among Family C G protein-coupled receptors and, in the case of the GABA(B) receptor and CREB2, may play a role in long-term changes in the nervous system...
  5. ncbi Advances in the molecular understanding of GABA(B) receptors
    A Billinton
    Dept of Neurobiology, Babraham Institute, Babraham, Cambridge, UK, CB2 4AT
    Trends Neurosci 24:277-82. 2001
    ....