Brian Greenwood

Summary

Country: UK

Publications

  1. ncbi request reprint Maternal immunisation in developing countries
    Brian Greenwood
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Vaccine 21:3436-41. 2003
  2. doi request reprint Combining community case management and intermittent preventive treatment for malaria
    Brian Greenwood
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    Trends Parasitol 27:477-80. 2011
  3. pmc Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants
    Matthew Cairns
    London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trans R Soc Trop Med Hyg 103:1199-201. 2009
  4. pmc The age patterns of severe malaria syndromes in sub-Saharan Africa across a range of transmission intensities and seasonality settings
    Arantxa Roca-Feltrer
    Department of Disease Control, Faculty of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Malar J 9:282. 2010
  5. pmc Intermittent preventive treatment for malaria in infants: a decision-support tool for sub-Saharan Africa
    Ilona Carneiro
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
    Bull World Health Organ 88:807-14. 2010
  6. doi request reprint Identification of hot spots of malaria transmission for targeted malaria control
    Teun Bousema
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom
    J Infect Dis 201:1764-74. 2010
  7. pmc Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy
    R Matthew Chico
    Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E7HT, UK
    Malar J 7:255. 2008
  8. pmc Intermittent screening and treatment versus intermittent preventive treatment of malaria in pregnancy: user acceptability
    Lucy A Smith
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK
    Malar J 9:18. 2010
  9. pmc Anti-malarial drugs and the prevention of malaria in the population of malaria endemic areas
    Brian Greenwood
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Malar J 9:S2. 2010
  10. doi request reprint Can we defeat meningococcal disease in low and middle income countries?
    Brian Greenwood
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Vaccine 30:B63-6. 2012

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Maternal immunisation in developing countries
    Brian Greenwood
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Vaccine 21:3436-41. 2003
    ..Thus, a strong case can be made for a trial of the effectiveness of maternal immunisation with a pneumococcal vaccine in preventing serious illness or death in young infants in developing countries...
  2. doi request reprint Combining community case management and intermittent preventive treatment for malaria
    Brian Greenwood
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    Trends Parasitol 27:477-80. 2011
    ....
  3. pmc Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants
    Matthew Cairns
    London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Trans R Soc Trop Med Hyg 103:1199-201. 2009
    ..However, because of concerns about development of drug resistance, new combinations of long-acting drugs are urgently needed...
  4. pmc The age patterns of severe malaria syndromes in sub-Saharan Africa across a range of transmission intensities and seasonality settings
    Arantxa Roca-Feltrer
    Department of Disease Control, Faculty of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Malar J 9:282. 2010
    ..A greater understanding of the relationship between transmission intensity, seasonality and the age-pattern of malaria is needed to guide appropriate targeting of malaria interventions in different epidemiological settings...
  5. pmc Intermittent preventive treatment for malaria in infants: a decision-support tool for sub-Saharan Africa
    Ilona Carneiro
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
    Bull World Health Organ 88:807-14. 2010
    ..To develop a decision-support tool to help policy-makers in sub-Saharan Africa assess whether intermittent preventive treatment in infants (IPTi) would be effective for local malaria control...
  6. doi request reprint Identification of hot spots of malaria transmission for targeted malaria control
    Teun Bousema
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom
    J Infect Dis 201:1764-74. 2010
    ..This heterogeneity creates opportunities for targeted interventions but only if hot spots of malaria transmission can be easily identified...
  7. pmc Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy
    R Matthew Chico
    Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E7HT, UK
    Malar J 7:255. 2008
    ..Several scientific and programmatic questions of interest to policymakers and programme managers are also presented that would need to be addressed before azithromycin-chloroquine could be adopted for use in IPTp...
  8. pmc Intermittent screening and treatment versus intermittent preventive treatment of malaria in pregnancy: user acceptability
    Lucy A Smith
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK
    Malar J 9:18. 2010
    ..This paper reports on a complementary study investigating the acceptability of the different strategies to women enrolled in the trial...
  9. pmc Anti-malarial drugs and the prevention of malaria in the population of malaria endemic areas
    Brian Greenwood
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Malar J 9:S2. 2010
    ..Mass drug administration probably has little role to play in control of mortality and morbidity from malaria but may have an important role in the final stages of an elimination campaign...
  10. doi request reprint Can we defeat meningococcal disease in low and middle income countries?
    Brian Greenwood
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Vaccine 30:B63-6. 2012
    ..In middle income countries, financial challenges predominate. These could be met by demonstration of the cost effectiveness of new meningococcal vaccines and through the introduction of a tiered-pricing system...
  11. pmc Age-patterns of malaria vary with severity, transmission intensity and seasonality in sub-Saharan Africa: a systematic review and pooled analysis
    Ilona Carneiro
    Disease Control and Vector Biology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 5:e8988. 2010
    ..We have, therefore, undertaken a pooled analysis of existing data from multiple sites to enable a comprehensive overview of the age-patterns of malaria outcomes under different epidemiological conditions in sub-Saharan Africa...
  12. pmc Vaccines and global health
    Brian Greenwood
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Philos Trans R Soc Lond B Biol Sci 366:2733-42. 2011
    ..Papers based on presentations at the discussion meeting and a summary of the main conclusions of the satellite meeting are included in this issue of Philosophical Transactions of the Royal Society B...
  13. doi request reprint Can malaria be eliminated?
    Brian Greenwood
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Trans R Soc Trop Med Hyg 103:S2-5. 2009
    ..However, malaria elimination (cessation of local transmission) is a realistic short- to medium-term goal for an increasing number of countries that are already bringing malaria under control...
  14. ncbi request reprint Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled trial
    Roly D Gosling
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Lancet 374:1521-32. 2009
    ..However, rising resistance to this combination is a concern. We investigated a shortacting and longacting antimalarial drug as alternative regimens for IPTi...
  15. pmc A mathematical model of serotype replacement in pneumococcal carriage following vaccination
    Christian Bottomley
    MRC Tropical Epidemiology Group, LSHTM, Keppel St, London WC1E 7HT, UK
    J R Soc Interface 10:20130786. 2013
    ..We examine the impact of a hypothetical vaccine that provides partial protection against all serotypes, and find that this reduces overall carriage, but is unable to eliminate low or medium prevalence serotypes. ..
  16. pmc Priorities for research on meningococcal disease and the impact of serogroup A vaccination in the African meningitis belt
    Danny Altmann
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    Vaccine 31:1453-7. 2013
    ..menafricar.org) and on the web site of the Centers for Disease Control (www.cdc.gov)...
  17. ncbi request reprint The Gates Malaria Partnership: a consortium approach to malaria research and capacity development
    Brian Greenwood
    Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
    Trop Med Int Health 17:558-63. 2012
    ....
  18. ncbi request reprint Progress in malaria control in endemic areas
    Brian Greenwood
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Travel Med Infect Dis 6:173-6. 2008
    ....
  19. ncbi request reprint Effects of misclassification of causes of death on the power of a trial to assess the efficacy of a pneumococcal conjugate vaccine in The Gambia
    Shabbar Jaffar
    Medical Research Council Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1 E7HT, UK
    Int J Epidemiol 32:430-6. 2003
    ..Causes assigned in this way have poor sensitivity and specificity. We illustrate the effects of this misclassification on the power of a large trial of a pneumococcal polysaccharide/protein conjugate vaccine with a mortality endpoint...
  20. ncbi request reprint Use of clinical algorithms for diagnosing malaria
    Daniel Chandramohan
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 7:45-52. 2002
    ..In highly endemic areas where laboratory support is not available, the policy of offering antimalarial drugs to all children presenting with a febrile illness recommended by the integrated child management initiative is appropriate...
  21. pmc Cluster randomised trial of intermittent preventive treatment for malaria in infants in area of high, seasonal transmission in Ghana
    Daniel Chandramohan
    London School of Hygiene and Tropical Medicine, London WC1E 7HT
    BMJ 331:727-33. 2005
    ..To evaluate the effects of intermittent preventive treatment for malaria in infants (IPTi) with sulfadoxine-pyrimethamine in an area of intense, seasonal transmission...
  22. ncbi request reprint Review: Intermittent preventive treatment--a new approach to the prevention of malaria in children in areas with seasonal malaria transmission
    Brian Greenwood
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
    Trop Med Int Health 11:983-91. 2006
    ..The potential benefits of intermittent preventive treatment in children are substantial; more research is needed to determine if this is a practical approach to malaria control...
  23. ncbi request reprint Malaria in pregnancy: priorities for research
    Brian Greenwood
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Lancet Infect Dis 7:169-74. 2007
    ....
  24. ncbi request reprint Malaria vaccines. Evaluation and implementation
    Brian Greenwood
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC 1E 7HT, UK
    Acta Trop 95:298-304. 2005
    ..Malaria vaccines will need to be more effective or more cost effective than these alternative control strategies or be able to provide substantial added value, when deployed with them if they are to be adopted widely...
  25. ncbi request reprint The molecular epidemiology of malaria
    Brian Greenwood
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 7:1012-21. 2002
    ..This review discusses how the use of molecular genetic techniques such as the polymerase chain reaction are helping in the management and prevention of malaria...
  26. pmc The safety of artemisinins during pregnancy: a pressing question
    Stephanie Dellicour
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, 50, Bedford Square, London, WC1B 3DP, UK
    Malar J 6:15. 2007
    ..There is an urgent need to assess the safety of these drugs in pregnant women who may be inadvertently exposed to or actively treated with ACTs...
  27. ncbi request reprint Malaria vaccine trials
    Brian Greenwood
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Chem Immunol 80:366-95. 2002
  28. ncbi request reprint Pneumococcal vaccination in developing countries
    Orin S Levine
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet 367:1880-2. 2006
  29. pmc Duration of protection against malaria and anaemia provided by intermittent preventive treatment in infants in Navrongo, Ghana
    Matthew Cairns
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 3:e2227. 2008
    ..This study investigated how the protective efficacy of IPTi against malaria and anaemia changes over time...
  30. ncbi request reprint Malaria--a shadow over Africa
    Louis H Miller
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
    Science 298:121-2. 2002
    ..The completed genomes of Plasmodium falciparum and its vector Anopheles gambiae represent a big step toward the discovery of these needed tools...
  31. pmc Treating malaria in Africa
    Brian Greenwood
    BMJ 328:534-5. 2004
  32. ncbi request reprint Between hope and a hard place
    Brian Greenwood
    Malaria Centre at the London School of Hygiene and Tropical Medicine, UK
    Nature 430:926-7. 2004
  33. pmc The contribution of social science research to malaria prevention and control
    Holly Ann Williams
    Partnership for Social Sciences in Malaria Control
    Bull World Health Organ 80:251-2. 2002
  34. ncbi request reprint The use of anti-malarial drugs to prevent malaria in the population of malaria-endemic areas
    Brian Greenwood
    Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Trop Med Hyg 70:1-7. 2004
    ....
  35. ncbi request reprint Elimination of Haemophilus influenzae type b (Hib) disease from The Gambia after the introduction of routine immunisation with a Hib conjugate vaccine: a prospective study
    Richard A Adegbola
    Medical Research Council Laboratories, The Gambia
    Lancet 366:144-50. 2005
    ..We investigated the effectiveness of the vaccine when delivered through the expanded programme on immunisation and the effect of national immunisation on incidence of Hib disease...
  36. ncbi request reprint Systematic review: Impact of meningococcal vaccination on pharyngeal carriage of meningococci
    Stephanie Dellicour
    Liverpool School of Tropical Medicine, Liverpool, UK
    Trop Med Int Health 12:1409-21. 2007
    ..To investigate the effect of meningococcal vaccines on pharyngeal carriage of meningococci...
  37. pmc A trial of the efficacy, safety and impact on drug resistance of four drug regimens for seasonal intermittent preventive treatment for malaria in Senegalese children
    Cheikh Sokhna
    Institut de Recherche pour le Developpement, Dakar, Senegal
    PLoS ONE 3:e1471. 2008
    ..We compared this regimen with three alternatives...
  38. ncbi request reprint Revaccination with Bacillus Calmette-Guerin (BCG) vaccine does not reduce morbidity from malaria in African children
    Amabelia Rodrigues
    Projecto de Saude de Bandim, Guine Bissau, Bissau
    Trop Med Int Health 12:224-9. 2007
    ..It is possible that this effect is mediated partly through an effect on malaria, a hypothesis supported by animal studies. We investigated whether revaccination with BCG at 19 months of age reduced morbidity from malaria...
  39. pmc An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria
    Seth Owusu-Agyei
    Kintmapo Health Research Centre, Ministry of Health, Kintampo, Ghana
    PLoS ONE 3:e2530. 2008
    ..A comparison of the efficacy and safety of these three drug combinations was necessary to make evidence based drug treatment policies...
  40. pmc Modelling the epidemiological impact of intermittent preventive treatment against malaria in infants
    Amanda Ross
    Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland
    PLoS ONE 3:e2661. 2008
    ..We investigated mechanisms proposed for the action of IPTi and made predictions of the likely impact on morbidity and mortality...
  41. ncbi request reprint Malaria in pregnancy in an area of stable and intense transmission: is it asymptomatic?
    Harry Tagbor
    Department of Community Health, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
    Trop Med Int Health 13:1016-21. 2008
    ..To report a study of the signs and symptoms of malarial infection during pregnancy in an area of stable and intense transmission...
  42. doi request reprint Brian Greenwood: making milestones in malaria research
    Priya Shetty
    Lancet 372:365. 2008
  43. ncbi request reprint Antischistosomal efficacy of artesunate combination therapies administered as curative treatments for malaria attacks
    Denis Boulanger
    Institut de Recherche pour le Developpement, UR024, Dakar, Senegal and Montpellier, France
    Trans R Soc Trop Med Hyg 101:113-6. 2007
    ..6% and 94.5%, respectively. Our findings indicate that artesunate, in addition to being a very effective treatment for uncomplicated malaria, can also sharply reduce the S. haematobium loads harboured by pre-school African children...
  44. ncbi request reprint Intermittent preventive antimalarial treatment in infants
    Brian Greenwood
    Clin Infect Dis 45:26-8. 2007