Kanchan Rao

Summary

Affiliation: Great Ormond Street
Country: UK

Publications

  1. ncbi request reprint Improved survival after unrelated donor bone marrow transplantation in children with primary immunodeficiency using a reduced-intensity conditioning regimen
    Kanchan Rao
    Department of Bone Marrow Transplant, Great Ormond Street Hospital, London, United Kingdom
    Blood 105:879-85. 2005
  2. doi request reprint Outcome of hematopoietic stem cell transplantation for adenosine deaminase-deficient severe combined immunodeficiency
    Amel Hassan
    Centre for Immunodeficiency, Molecular Immunology Unit, UCL Institute of Child Health, London, United Kingdom
    Blood 120:3615-24; quiz 3626. 2012
  3. ncbi request reprint Successful treatment of lymphoproliferative disease complicating primary immunodeficiency/immunodysregulatory disorders with reduced-intensity allogeneic stem-cell transplantation
    Jonathan M Cohen
    Department of Clinical Immunology, Great Ormond Street Hospital, London, United Kingdom
    Blood 110:2209-14. 2007
  4. ncbi request reprint Serial transplantation of mismatched donor hematopoietic cells between HLA-identical sibling pairs with congenital immunodeficiency: in vivo tolerance permits rapid immune reconstitution following T-replete transplantation without GVHD in the secondary re
    Jonathan M Cohen
    Department of Bone Marrow Transplantation, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, United Kingdom
    Blood 108:2124-6. 2006
  5. doi request reprint Pulmonary hypertension following haematopoietic stem cell transplantation for primary haemophagocytic lymphohistiocytosis
    Ulrike Zeilhofer
    Department of Bone Marrow Transplantation, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
    Pediatr Blood Cancer 60:521-3. 2013
  6. doi request reprint Mesenchymal stem cells exert differential effects on alloantigen and virus-specific T-cell responses
    Helen Karlsson
    Molecular Immunology Unit, Institute of Child Health, London, United Kingdom
    Blood 112:532-41. 2008
  7. doi request reprint Omission of in vivo T-cell depletion promotes rapid expansion of naïve CD4+ cord blood lymphocytes and restores adaptive immunity within 2 months after unrelated cord blood transplant
    Robert Chiesa
    Bone Marrow Transplantation Department, Great Ormond Street Hospital, London, UK
    Br J Haematol 156:656-66. 2012
  8. ncbi request reprint Early pediatric anthracycline cardiotoxicity: managed by serial heart and bone marrow transplantation
    Jasveer S Mangat
    Department of Paediatric Cardiology, Great Ormond Street Hospital, London, UK
    J Heart Lung Transplant 26:658-60. 2007
  9. ncbi request reprint Stem cell transplantation with reduced-intensity conditioning for hemophagocytic lymphohistiocytosis
    Nichola Cooper
    Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
    Blood 107:1233-6. 2006
  10. ncbi request reprint Increased incidence of EBV-related disease following paediatric stem cell transplantation with reduced-intensity conditioning
    Jonathan Cohen
    Department of Bone Marrow Transplantation, Great Ormond Street Hospital NHS Trust, London, UK
    Br J Haematol 129:229-39. 2005

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Improved survival after unrelated donor bone marrow transplantation in children with primary immunodeficiency using a reduced-intensity conditioning regimen
    Kanchan Rao
    Department of Bone Marrow Transplant, Great Ormond Street Hospital, London, United Kingdom
    Blood 105:879-85. 2005
    ....
  2. doi request reprint Outcome of hematopoietic stem cell transplantation for adenosine deaminase-deficient severe combined immunodeficiency
    Amel Hassan
    Centre for Immunodeficiency, Molecular Immunology Unit, UCL Institute of Child Health, London, United Kingdom
    Blood 120:3615-24; quiz 3626. 2012
    ..These data detail for the first time the outcomes of HCT for ADA-SCID and show that, if patients survive HCT, long-term cellular and humoral immune recovery is achieved...
  3. ncbi request reprint Successful treatment of lymphoproliferative disease complicating primary immunodeficiency/immunodysregulatory disorders with reduced-intensity allogeneic stem-cell transplantation
    Jonathan M Cohen
    Department of Clinical Immunology, Great Ormond Street Hospital, London, United Kingdom
    Blood 110:2209-14. 2007
    ..With careful monitoring and pre-emptive therapy, we advocate this RIC SCT approach to patients with PID who have pre-existing EBV-LPD...
  4. ncbi request reprint Serial transplantation of mismatched donor hematopoietic cells between HLA-identical sibling pairs with congenital immunodeficiency: in vivo tolerance permits rapid immune reconstitution following T-replete transplantation without GVHD in the secondary re
    Jonathan M Cohen
    Department of Bone Marrow Transplantation, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, United Kingdom
    Blood 108:2124-6. 2006
    ....
  5. doi request reprint Pulmonary hypertension following haematopoietic stem cell transplantation for primary haemophagocytic lymphohistiocytosis
    Ulrike Zeilhofer
    Department of Bone Marrow Transplantation, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
    Pediatr Blood Cancer 60:521-3. 2013
    ..PHT may be an association with HLH and physicians treating HLH should be aware of this potential association...
  6. doi request reprint Mesenchymal stem cells exert differential effects on alloantigen and virus-specific T-cell responses
    Helen Karlsson
    Molecular Immunology Unit, Institute of Child Health, London, United Kingdom
    Blood 112:532-41. 2008
    ..These data have major implications for immunotherapy of GVHD with MSCs and suggest that the effector functions of virus-specific T cells may be retained after MSC infusion...
  7. doi request reprint Omission of in vivo T-cell depletion promotes rapid expansion of naïve CD4+ cord blood lymphocytes and restores adaptive immunity within 2 months after unrelated cord blood transplant
    Robert Chiesa
    Bone Marrow Transplantation Department, Great Ormond Street Hospital, London, UK
    Br J Haematol 156:656-66. 2012
    ..We postulate that this relates to the specific immunological and ontological qualities of fetal-derived lymphocytes...
  8. ncbi request reprint Early pediatric anthracycline cardiotoxicity: managed by serial heart and bone marrow transplantation
    Jasveer S Mangat
    Department of Paediatric Cardiology, Great Ormond Street Hospital, London, UK
    J Heart Lung Transplant 26:658-60. 2007
    ..This case is unique in the literature. We believe it offers an alternative strategy for children with hematologic malignancies, where severe early post-anthracycline cardiotoxicity might preclude bone marrow transplantation...
  9. ncbi request reprint Stem cell transplantation with reduced-intensity conditioning for hemophagocytic lymphohistiocytosis
    Nichola Cooper
    Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
    Blood 107:1233-6. 2006
    ..Three of 9 survivors have mixed chimerism but remain free of disease. In summary, RIC compares favorably to conventional SCT with long-term disease control in surviving patients despite a significant incidence of mixed chimerism...
  10. ncbi request reprint Increased incidence of EBV-related disease following paediatric stem cell transplantation with reduced-intensity conditioning
    Jonathan Cohen
    Department of Bone Marrow Transplantation, Great Ormond Street Hospital NHS Trust, London, UK
    Br J Haematol 129:229-39. 2005
    ..This probably reflects the profound immunosuppression following RIC SCT, together with the incomplete ablation of recipient-derived B cells...