Stephen D Marks

Summary

Affiliation: Great Ormond Street
Country: UK

Publications

  1. pmc How have the past 5 years of research changed clinical practice in paediatric nephrology?
    Stephen D Marks
    Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1N 3JH, UK
    Arch Dis Child 92:357-61. 2007
  2. doi request reprint Renal FMD may not confer a familial hypertensive risk nor is it caused by ACTA2 mutations
    Stephen D Marks
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK
    Pediatr Nephrol 26:1857-61. 2011
  3. doi request reprint Modern therapeutic strategies for paediatric systemic lupus erythematosus and lupus nephritis
    Stephen D Marks
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Acta Paediatr 99:967-74. 2010
  4. ncbi request reprint Clinicopathological correlations of paediatric lupus nephritis
    Stephen D Marks
    Nephro Urology Unit, Institute of Child Health, London, UK
    Pediatr Nephrol 22:77-83. 2007
  5. ncbi request reprint Imaging in childhood urinary tract infections: time to reduce investigations
    Stephen D Marks
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1N 3JH, UK
    Pediatr Nephrol 23:9-17. 2008
  6. doi request reprint Renal artery revascularisation can restore kidney function with absent radiotracer uptake
    Yincent Tse
    Department of Nephrology, Great Ormond Street Hospital for Children, NHS Trust, Great Ormond Street, London, WC1N 3JH, UK
    Pediatr Nephrol 27:2153-7. 2012
  7. ncbi request reprint B lymphocyte depletion therapy in children with refractory systemic lupus erythematosus
    Stephen D Marks
    Department of Paediatric Nephrology, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, UK
    Arthritis Rheum 52:3168-74. 2005
  8. doi request reprint Systemic polyarteritis nodosa in the young: a single-center experience over thirty-two years
    Despina Eleftheriou
    Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
    Arthritis Rheum 65:2476-85. 2013
  9. pmc Imaging in the evaluation of renovascular disease
    Kjell Tullus
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK
    Pediatr Nephrol 25:1049-56. 2010
  10. doi request reprint Multicentre prospective randomised trial of tacrolimus, azathioprine and prednisolone with or without basiliximab: two-year follow-up data
    Nicholas J A Webb
    Department of Paediatric Nephrology, Royal Manchester Children s Hospital, Manchester, M27 4HA, UK
    Pediatr Nephrol 24:177-82. 2009

Collaborators

Detail Information

Publications48

  1. pmc How have the past 5 years of research changed clinical practice in paediatric nephrology?
    Stephen D Marks
    Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1N 3JH, UK
    Arch Dis Child 92:357-61. 2007
    ....
  2. doi request reprint Renal FMD may not confer a familial hypertensive risk nor is it caused by ACTA2 mutations
    Stephen D Marks
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK
    Pediatr Nephrol 26:1857-61. 2011
    ..Furthermore, in our cohort, FMD was not caused by ACTA2 mutations...
  3. doi request reprint Modern therapeutic strategies for paediatric systemic lupus erythematosus and lupus nephritis
    Stephen D Marks
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Acta Paediatr 99:967-74. 2010
    ..In this article, we explore current evidence to effectively treat children and adolescents with SLE with or without LN...
  4. ncbi request reprint Clinicopathological correlations of paediatric lupus nephritis
    Stephen D Marks
    Nephro Urology Unit, Institute of Child Health, London, UK
    Pediatr Nephrol 22:77-83. 2007
    ..73 m(2) in patients with diffuse global sclerosing [class IV-G(C)] LN. The new classification allows expanded histopathological grading of LN with further delineation of classes III and IV with activity and chronicity indices...
  5. ncbi request reprint Imaging in childhood urinary tract infections: time to reduce investigations
    Stephen D Marks
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1N 3JH, UK
    Pediatr Nephrol 23:9-17. 2008
    ....
  6. doi request reprint Renal artery revascularisation can restore kidney function with absent radiotracer uptake
    Yincent Tse
    Department of Nephrology, Great Ormond Street Hospital for Children, NHS Trust, Great Ormond Street, London, WC1N 3JH, UK
    Pediatr Nephrol 27:2153-7. 2012
    ..Conventional treatment of these children has been nephrectomy of the poorly functioning kidney to normalise their blood pressure (BP)...
  7. ncbi request reprint B lymphocyte depletion therapy in children with refractory systemic lupus erythematosus
    Stephen D Marks
    Department of Paediatric Nephrology, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, UK
    Arthritis Rheum 52:3168-74. 2005
    ..To determine the safety and efficacy of B lymphocyte depletion therapy in patients with refractory childhood-onset systemic lupus erythematosus (SLE)...
  8. doi request reprint Systemic polyarteritis nodosa in the young: a single-center experience over thirty-two years
    Despina Eleftheriou
    Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
    Arthritis Rheum 65:2476-85. 2013
    ..Polyarteritis nodosa (PAN) is a rare disease of childhood. The aims of this study were to describe the clinical features, treatment, and outcome of systemic childhood PAN and to identify predictors of relapse...
  9. pmc Imaging in the evaluation of renovascular disease
    Kjell Tullus
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK
    Pediatr Nephrol 25:1049-56. 2010
    ..Doppler ultrasonography, computed tomography (CT) angiography and magnetic resonance (MR) angiography can all be helpful, but none has, at present, high enough sensitivity to rule out RVD in a child with a suggestion of that diagnosis...
  10. doi request reprint Multicentre prospective randomised trial of tacrolimus, azathioprine and prednisolone with or without basiliximab: two-year follow-up data
    Nicholas J A Webb
    Department of Paediatric Nephrology, Royal Manchester Children s Hospital, Manchester, M27 4HA, UK
    Pediatr Nephrol 24:177-82. 2009
    ..These data provide further evidence of a lack of benefit associated with the addition of basiliximab to a TAS regimen for European paediatric renal transplant recipients at low immunological risk...
  11. doi request reprint Urinary monocyte chemoattractant protein-1 correlates with disease activity in lupus nephritis
    Stephen D Marks
    Nephro Urology Unit, University College London Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK
    Pediatr Nephrol 25:2283-8. 2010
    ..04). These results provide evidence of increased urinary--but not plasma--MCP-1 levels in children with LN, which correlates well with SLE disease activity as measured by the BILAG index...
  12. doi request reprint Dense B cell infiltrates in paediatric renal transplant biopsies are predictive of allograft loss
    Mordi R Muorah
    Departments of Paediatric Nephrology, Great Ormond Street Hospital for Childrens NHS Trust, Great Ormond Street, London, UK
    Pediatr Transplant 13:217-22. 2009
    ..This observation raises the possibility of future studies examining the efficacy of B cell depletion therapy in this clinical context...
  13. doi request reprint Maximising living donation with paediatric blood-group-incompatible renal transplantation
    Nizam Mamode
    Department of Transplantation, Renal Unit, Guy s Hospital, London, SE1 9RT, UK
    Pediatr Nephrol 28:1037-40. 2013
    ....
  14. doi request reprint Interventions for impaired bladders in paediatric renal transplant recipients with lower urinary tract dysfunction
    Naji Al-Khudairi
    Renal Unit, Guys Hospital, London, UK
    Transpl Int 26:428-34. 2013
    ..The mode of intervention and timing of intervention, in relation to transplant, do not influence outcomes if guided by careful assessment and investigation...
  15. doi request reprint Results of surgical treatment for renovascular hypertension in children: 30 year single centre experience
    Marike B Stadermann
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, UK
    Nephrol Dial Transplant 25:807-13. 2010
    ....
  16. doi request reprint Indications for use and safety of rituximab in childhood renal diseases
    Kjell Tullus
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, England, UK
    Pediatr Nephrol 28:1001-9. 2013
    ..We will here review the scientific basis for the use of rituximab in children with renal diseases and give recommendations both regarding its clinical use and need for further research...
  17. doi request reprint Is laparoscopic donation safe for paediatric recipients?--a study of 85 paediatric recipients comparing open and laparoscopic donor nephrectomy
    Pankaj Chandak
    Department of Transplantation, Renal Unit, Guy s, St Thomas and Evelina Children s Hospital, London, UK
    Nephrol Dial Transplant 27:845-9. 2012
    ..Small studies have shown no difference in graft survival when compared with open techniques, but previous data from United Network for Organ Sharing suggests a higher incidence of rejection in laparoscopically procured kidneys...
  18. doi request reprint Vitamin D deficiency is associated with short stature and may influence blood pressure control in paediatric renal transplant recipients
    Rukshana Shroff
    Renal Unit, Great Ormond Street Hospital for Children NHS Trust and Institute of Child Health London, London, WC1N 3JH, UK
    Pediatr Nephrol 26:2227-33. 2011
    ..Further studies are required to test if routine supplementation with ergo or cholecalciferol is safe and effective in children after renal transplantation...
  19. doi request reprint Glomerular expression of monocyte chemoattractant protein-1 is predictive of poor renal prognosis in pediatric lupus nephritis
    Stephen D Marks
    Institute of Child Health, 30 Guilford Street, London, UK
    Nephrol Dial Transplant 23:3521-6. 2008
    ..Monocyte chemoattractant protein-1 (MCP-1) is upregulated and it recruits and activates inflammatory cells in murine lupus nephritis (LN)...
  20. doi request reprint Induction therapy: why, when, and which agent?
    Leah Krischock
    Department of Paediatric Nephrology, Royal Hospital for Sick Children, Glasgow, UK
    Pediatr Transplant 14:298-313. 2010
    ..The aim of this review is to summarize the current literature relating to the use of antibody agents for induction in paediatric solid organ transplantation...
  21. doi request reprint Chronic kidney disease in children following lung and heart-lung transplantation
    Christian Benden
    Cardio Respiratory and Critical Care Division, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Pediatr Transplant 13:104-10. 2009
    ..Unlike in adults, we were unable to detect any predictors of renal impairment in pediatric lung transplant recipients...
  22. doi request reprint Biologic therapy in primary systemic vasculitis of the young
    Despina Eleftheriou
    Rheumatology Department, Institute of Child Health, London, UK
    Rheumatology (Oxford) 48:978-86. 2009
    ..To describe the biologic treatment regimens and report the efficacy and safety of biologic therapies in a multicentre series of children with primary systemic vasculitis (PSV)...
  23. ncbi request reprint Targeted B-cell depletion therapy in childhood-onset systemic lupus erythematosus: progress to date
    Stephen D Marks
    Nephro Urology Unit, Institute of Child Health, London, UK
    Paediatr Drugs 9:371-8. 2007
    ....
  24. doi request reprint Rituximab in refractory nephrotic syndrome
    Agnieszka Prytuła
    Department of Paediatric Nephrology, Great Ormond Street Hospital NHS Trust, London, UK
    Pediatr Nephrol 25:461-8. 2010
    ..The good initial response in group 3 can be biased by the accompanying treatments that were administered at the same time as rituximab. Controlled prospective trials are required to establish the value of rituximab in idiopathic NS...
  25. doi request reprint Update on imaging for suspected renovascular hypertension in children and adolescents
    Stephen D Marks
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
    Curr Hypertens Rep 14:591-5. 2012
    ....
  26. doi request reprint Prevalence and complications of chronic kidney disease in paediatric renal transplantation: a K/DOQI perspective
    Rajiv Sinha
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK
    Nephrol Dial Transplant 25:1313-20. 2010
    ..Further multi-centre prospective studies are required to substantiate our findings and to explore whether early identification and intervention can improve renal allograft outcome...
  27. doi request reprint Comparison of parameters of chronic kidney disease following paediatric preemptive versus non-preemptive renal transplantation
    Rajiv Sinha
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Pediatr Transplant 14:583-8. 2010
    ..002). We demonstrated improved CKD parameters and lower use of CKD medications among PRT when compared with NPRT. This finding should act as an added impetus for PRT programmes...
  28. ncbi request reprint Renal tubular dysfunction in children with systemic lupus erythematosus
    Stephen D Marks
    Nephro Urology Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Pediatr Nephrol 20:141-8. 2005
    ..Evidence of tubular dysfunction in lupus non-nephritis patients may help to identify lupus nephritis prior to the onset of albuminuria...
  29. doi request reprint Renovascular hypertension in children
    Kjell Tullus
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Lancet 371:1453-63. 2008
    ..Modern treatment provided by a multidisciplinary team of paediatric nephrologists, interventional radiologists, and vascular surgeons offers good long-term treatment results...
  30. doi request reprint New immunosuppressants in pediatric solid organ transplantation
    Stephen D Marks
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London, UK
    Curr Opin Organ Transplant 17:503-8. 2012
    ....
  31. pmc Non-viral infections in children after renal transplantation
    Francesca Mencarelli
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, England, UK
    Pediatr Nephrol 27:1465-76. 2012
    ....
  32. ncbi request reprint Current issues in pediatric lupus nephritis: role of revised histopathological classification
    Stephen D Marks
    Nephro Urology Unit, Institute of Child Health, London, UK
    Fetal Pediatr Pathol 25:297-309. 2006
    ..However, we are many years away from completely understanding the etiopathogenesis of LN and the predictive role of the revised histological classification for direction of patient management...
  33. doi request reprint Standard dosing of tacrolimus leads to overexposure in pediatric renal transplantation recipients
    Joshua Y Kausman
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Pediatr Transplant 12:329-35. 2008
    ..We therefore outline a regimen restricting tacrolimus dosage given to larger/older patients, but emphasize the need for a prospective randomized trial to define optimal dosing...
  34. ncbi request reprint Distribution of ABO blood group antibody titers in pediatric patients awaiting renal transplantation: implications for organ allocation policy
    A Nicholas R Barnett
    Renal and Transplant Department, Guy s Hospital, Guy s and St Thomas National Health Service Foundation Trust, London, UK
    Transplantation 94:362-8. 2012
    ..This study is the first to examine the distribution of ABO blood group antibody titers in a population of pediatric patients on the deceased-donor renal transplantation waiting list...
  35. doi request reprint What is the value of magnetic resonance venography in children before renal transplantation?
    Mark G Meister
    Department of Paediatric Radiology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, England, UK
    Pediatr Nephrol 23:1157-62. 2008
    ..MRV infrequently contributes beneficial information, is difficult to justify as a screening tool, and due to the risks of gadolinium in uraemia, should only be used on an individual patient basis...
  36. doi request reprint Ten-year follow-up of children after acute renal failure from a developing country
    Rajiv Sinha
    1Specialist Registrar in Paediatric Nephrology, Great Ormond Street Hospital, London, UK
    Nephrol Dial Transplant 24:829-33. 2009
    ..The aim of this study was to look at the spectrum of ARF on presentation at a tertiary centre in Kolkata, India, with subsequent 10 years of follow-up...
  37. doi request reprint Vasculitis in children and adolescents: clinical presentation, etiopathogenesis, and treatment
    Kjell Tullus
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1N 3JH, UK
    Paediatr Drugs 11:375-80. 2009
    ..The more rare vasculitides are generally much more severe, often needing treatment with high doses of corticosteroids and immunosuppressant agents such as cyclophosphamide, azathioprine, and mycophenolate mofetil...
  38. doi request reprint Postnatal investigation of fetal renal disease
    Rose De Bruyn
    Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, UK
    Semin Fetal Neonatal Med 13:133-41. 2008
    ..However, magnetic resonance urography may have increasing importance in becoming the investigation of choice of the future for more complex cases...
  39. doi request reprint Clinical significance of isolated v lesions in paediatric renal transplant biopsies: muscular arteries required to refute the diagnosis of acute rejection
    Chrysothemis C Brown
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
    Transpl Int 27:170-5. 2014
    ..This may result in suboptimal therapy with possible adverse effects on renal outcome. ..
  40. doi request reprint Successful treatment of central nervous system PTLD with rituximab and cranial radiotherapy
    Valerie Said-Conti
    Department of Paediatric Nephrology, Great Ormond Street Hospital NHS Trust, London, UK
    Pediatr Nephrol 28:2053-6. 2013
    ..The modalities of treatment include reduction in immunosuppression, cranial radiotherapy (CRT), intravenous and intrathecal rituximab when CD20 is expressed on B-lymphocytes and PTLD cells, and chemotherapy...
  41. doi request reprint High prevalence of food sensitisation in young children with liver disease: a clue to food allergy pathogenesis?
    Chrysothemis Brown
    Department of Paediatrics, Imperial College London, London, UK
    Pediatr Allergy Immunol 23:771-8. 2012
    ..The pathogenesis of food allergy is not completely understood - animal models suggest hepatic mechanisms may be important for immune tolerance to orally ingested antigens, but there is little direct evidence for this in humans...
  42. doi request reprint Autoantibodies in systemic lupus erythematosus
    Stephen D Marks
    Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK
    Pediatr Nephrol 27:1855-68. 2012
    ..SLE patients have dysregulation of inflammatory cytokines, chemokines and immune response-related genes, as well as of the genes involved in apoptosis, signal transduction and the cell cycle...
  43. pmc Primary hyperoxaluria type 1
    Michal J Ajzensztejn
    Great Ormond Street Hospital for Children NHS Trust, London, UK
    Arch Dis Child 92:197. 2007
  44. doi request reprint Treating the causes of paediatric hypertension using non-invasive physiological parameters
    Joe Brierley
    Paediatric and Neonatal Intensive Care Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Med Hypotheses 75:439-41. 2010
    ..Modern therapeutic strategies targeted at a child's individual physiological derangement should offer more rapid and effective anti-hypertensive medication than current therapy based on physician preference...
  45. doi request reprint Electronic prescribing reduced prescribing errors in a pediatric renal outpatient clinic
    Yogini Hariprasad Jani
    Centre for Pediatric Pharmacy Research, The School of Pharmacy, University of London and the Institute of Child Health, University College London, London, UK
    J Pediatr 152:214-8. 2008
    ..To assess the effect of an electronic prescribing (EP) system on the incidence and type of prescribing errors and the number of error-free visits...
  46. ncbi request reprint Renal transplantation or bladder augmentation first? A comparison of complications and outcomes in children
    Arash K Taghizadeh
    Great Ormond Street Hospital for Children NHS Trust, London WC1N 3JH, UK
    BJU Int 100:1365-70. 2007
    ..To identify whether the order of performing transplant and bladder reconstruction operations in children who need both operations affects outcome of either operation...
  47. ncbi request reprint Evaluation of renal improvement in juvenile systemic lupus erythematosus: Comment on the articles by Ruperto et al
    Stephen D Marks
    Arthritis Rheum 55:990-1; author reply 991. 2006
  48. ncbi request reprint Neonatal renal venous thrombosis: clinical outcomes and prevalence of prothrombotic disorders
    Stephen D Marks
    Division of Nephrology, Department of Pediatrics, Hospital for Sick Children and University of Toronto, Ontario, Canada
    J Pediatr 146:811-6. 2005
    ..To determine clinical outcomes and the prevalence of prothrombotic conditions in patients who had neonatal renal venous thrombosis (RVT)...