Katherine L Brown
Affiliation: Great Ormond Street
- Cost utility evaluation of extracorporeal membrane oxygenation as a bridge to transplant for children with end-stage heart failure due to dilated cardiomyopathyKate L Brown
Cardiac Unit, Great Ormond Street Hospital for Sick Children, London, United Kingdom
J Heart Lung Transplant 28:32-8. 2009..Extracorporeal membrane oxygenation (ECMO) and cardiac transplantation are recognized to be expensive...
- Extracorporeal membrane oxygenation and term neonatal respiratory failure deaths in the United Kingdom compared with the United States: 1999 to 2005Kate L Brown
Cardiac Critical Care, Great Ormond Street Hospital for Children, London, UK
Pediatr Crit Care Med 11:60-5. 2010..To compare national neonatal extracorporeal membrane oxygenation data and deaths from primary respiratory disorders of term neonates between the United Kingdom and the United States from 1999 to 2005...
- Adverse family social circumstances and outcome in pediatric cardiac transplant recipients at a UK centerKate L Brown
Cardiac Unit, Great Ormond Street Hospital, London, UK
J Heart Lung Transplant 28:1267-72. 2009..Socioeconomic disadvantage is known to prejudice certain health-related outcomes...
- Neonatal extra-corporeal life support: indications and limitationsKate L Brown
Cardiac Intensive Care Unit, Great Ormond Street Hospital for Sick Children, Great Ormond Street, London WC1N 3JH, UK
Early Hum Dev 84:143-8. 2008..Further research is required in order to determine the optimal methods for patient selection and to establish important predictors of outcome including the longterm neurological development of survivors...
- The relationship between workload and medical staffing levels in a paediatric cardiac intensive care unitKatherine L Brown
Cardiac Unit, Great Ormond Street Hospital NHS Trust, London WC1N 3JH, UK
Intensive Care Med 37:326-33. 2011..To evaluate the matching between workload in a paediatric cardiac intensive care unit (ICU) and the corresponding medical staffing levels over a 24-h period...
- Delayed diagnosis of congenital heart disease worsens preoperative condition and outcome of surgery in neonatesK L Brown
Cardiac Unit, Great Ormond Street Hospital for Sick Children, London, UK
Heart 92:1298-302. 2006..To assess whether the route by which neonatal congenital heart disease (CHD) is first recognised influences outcome after surgery...
- Outcome in neonates with congenital heart disease referred for respiratory extracorporeal membrane oxygenationKate L Brown
Cardiac Intensive Care Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK
Acta Paediatr 94:1280-4. 2005....
- ECLS for children with late (post-discharge) rejection after heart transplantationAstrid E Lammers
Department of Paediatric Cardiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
Pediatr Transplant 17:336-42. 2013..ECLS thus appears to be a good rescue therapy for children with severe acute rejection post OHT, refractory to conventional treatment, leading to good medium-term outcome...
- Acute rejection after paediatric heart transplantation: far less common and less severeAstrid E Lammers
Department of Paediatric Cardiology, Great Ormond Street Hospital for Children, London, UK
Transpl Int 23:38-46. 2010..Sirolimus without a calcineurin inhibitor was associated with more rejection episodes, whereas tacrolimus and mycophenolate appeared to provide the best protective profile...
- Predictors of outcome for children requiring respiratory extra-corporeal life support: implications for inclusion and exclusion criteriaNazima Pathan
Cardiac Critical Care Unit, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK
Intensive Care Med 34:2256-63. 2008..Our aims were: (1) to analyse predictors of outcome and (2) comment on inclusion and exclusion criteria...
- Monitoring risk-adjusted outcomes in congenital heart surgery: does the appropriateness of a risk model change with time?Victor T Tsang
Cardiac Unit, Great Ormond Street Hospital, London, United Kingdom
Ann Thorac Surg 87:584-7. 2009..A question arises as to whether the risk model used remains appropriate over time...
- Role of immunoglobulin supplementation for secondary immunodeficiency associated with chylothorax after pediatric cardiothoracic surgeryAparna U Hoskote
Cardiac Critical Care Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK
Pediatr Crit Care Med 13:535-41. 2012..To evaluate whether intravenous immunoglobulin was linked to a reduction in sepsis in patients with prolonged chylothoraces postpediatric cardiothoracic surgery...
- The impact of mechanical ventilation time before initiation of extracorporeal life support on survival in pediatric respiratory failure: a review of the Extracorporeal Life Support RegistryMichele B Domico
Department of Pediatrics, Division of Critical Care, Children s Hospital of Orange County, Orange, CA, USA
Pediatr Crit Care Med 13:16-21. 2012..Previous studies suggest patients who received >7-10 days of mechanical ventilation were not acceptable extracorporeal life support candidates as a result of irreversible lung damage...
- Mortality as a measure of quality of care in infants with congenital cardiovascular malformations following surgeryHanna A Jensen
Cardiac Unit, Great Ormond Street Hospital for Children, Great Ormond Street, London WC1N 3JH, UK
Br Med Bull 111:5-15. 2014..In the rapidly developing arena of paediatric cardiac surgery, the insightful analysis of mortality figures is challenging...
- Cardiac ECMO for biventricular hearts after paediatric open heart surgeryR R Chaturvedi
Randall Centre, King s College, London, UK
Heart 90:545-51. 2004..To delineate predictors of hospital survival in a large series of children with biventricular physiology supported with extracorporeal membrane oxygenation (ECMO) after open heart surgery...
- Healthcare-associated infection in pediatric patients on extracorporeal life support: The role of multidisciplinary surveillanceKate L Brown
Cardiac Intensive Care Unit, Great Ormond Street Hospital for Sick Children, Institute of Child Health, London, UK
Pediatr Crit Care Med 7:546-50. 2006..To describe the use of a multidisciplinary approach to sepsis surveillance and evaluate impact on outcome...
- Percutaneous left ventricular "vent" insertion for left heart decompression during extracorporeal membrane oxygenationMichael M H Cheung
Cardiothoracic Unit, Great Ormond Street Hospital, London, UK
Pediatr Crit Care Med 4:447-9. 2003..Description of a novel method of left ventricular decompression by a percutaneous technique under transthoracic echocardiographic guidance...
- Risk factors for long intensive care unit stay after cardiopulmonary bypass in childrenKate L Brown
Cardiac Intensive Care Unit, Great Ormond Street Hospital for Sick Children, London, UK
Crit Care Med 31:28-33. 2003..To identify factors associated with longer ICU stays that are potential targets for quality improvement...
- Transcatheter closure of a patent arterial duct in a patient on veno-arterial extracorporeal membrane oxygenationKate L Brown
Cardiac Intensive Care Unit, Great Ormond Street Hospital, London, UK
Intensive Care Med 28:501-3. 2002..This is the first report of transcatheter occlusion of a patent arterial duct in an infant on ECMO support...