Karl A Bettelheim
Affiliation: Great Ormond Street
- The non-O157 shiga-toxigenic (verocytotoxigenic) Escherichia coli; under-rated pathogensKarl A Bettelheim
Crit Rev Microbiol 33:67-87. 2007..The animal host-specificity of these STEC is also reviewed. In conclusion some methods of improving isolation of these pathogens is addressed...
- Treatment of enterohemorrhagic Escherichia coli (EHEC) infection and hemolytic uremic syndrome (HUS)Paul N Goldwater
Microbiology and Infectious Diseases, SA Pathology at the Women s and Children s Hospital, and Discipline of Paediatrics, University of Adelaide, 72 King William Road, North Adelaide, South Australia, Australia
BMC Med 10:12. 2012..Due to the complexity of pathogenesis, it is likely a multitargeted approach is warranted. Developments in terms of these treatments are discussed...
- Emergence and spread of two distinct clonal groups of multidrug-resistant Escherichia coli in a veterinary teaching hospital in AustraliaHanna E Sidjabat
School of Veterinary Science, University of Queensland, Brisbane, QLD 4072, Australia
J Med Microbiol 55:1125-34. 2006..These results confirm that in this particular outbreak, canine MDREC were highly clonal and CG 2 MDREC may colonize both humans and dogs...
- Comparison of virulence gene profiles of Escherichia coli strains isolated from healthy and diarrheic swineToni A Chapman
Immunology and Molecular Diagnostic Research Unit, Elizabeth Macarthur Agriculture Institute, PMB 8, Camden, NSW 2570, Australia
Appl Environ Microbiol 72:4782-95. 2006..coli strains have evolved and are engaged in the dynamic process of losing or acquiring VGs within the pig population...
- Bovine feces from animals with gastrointestinal infections are a source of serologically diverse atypical enteropathogenic Escherichia coli and Shiga toxin-producing E. coli strains that commonly possess intiminMichael A Hornitzky
Elizabeth Macarthur Agricultural Institute, New South Wales Department of Primary Industries, Private Mail Bag 8, Camden, New South Wales 2570, Australia
Appl Environ Microbiol 71:3405-12. 2005..1% of samples), and direct culture on BVCC agar was the most successful method for the isolation of EPEC (14.1% samples). These studies show that diarrheagenic calves and cattle represent important reservoirs of eae-positive E. coli...
- Escherichia coli and community-acquired gastroenteritis, Melbourne, AustraliaRoy M Robins-Browne
Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria 3010, Australia
Emerg Infect Dis 10:1797-805. 2004..Apart from the surface protein, intimin, no virulence determinant or phenotype was uniformly present in atypical EPEC strains. This study shows that atypical EPEC are an important cause of gastroenteritis in Melbourne...
- Serotypes and virulence gene profiles of shiga toxin-producing Escherichia coli strains isolated from feces of pasture-fed and lot-fed sheepSteven P Djordjevic
Elizabeth Macarthur Agricultural Institute, NSW Agriculture, Camden, New South Wales 2570, Australia
Appl Environ Microbiol 70:3910-7. 2004..Collectively, our data show that Australian sheep are colonized by diverse cSTEC serotypes that are rarely isolated from healthy Australian cattle...
- Distribution of intimin subtypes among Escherichia coli isolates from ruminant and human sourcesVidiya Ramachandran
Elizabeth Macarthur Agricultural Institute, Camden, New South Wales, 2570, Australia
J Clin Microbiol 41:5022-32. 2003..Our data confirm that ruminants are an important source of serologically and genetically diverse intimin-containing E. coli strains...
- Bovine non-O157 Shiga toxin 2-containing Escherichia coli isolates commonly possess stx2-EDL933 and/or stx2vhb subtypesKim N Brett
Elizabeth Macarthur Agricultural Institute, Camden, New South Wales, Australia 2570
J Clin Microbiol 41:2716-22. 2003..Three of the four were from separate sporadic cases of HUS, and one was from an unknown source...
- Non-O157 verotoxin-producing Escherichia coli: a problem, paradox, and paradigmKarl A Bettelheim
National Escherichia coli Reference Laboratory, Microbiological Diagnostic Unit, Public Health Laboratory, Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3052, Australia
Exp Biol Med (Maywood) 228:333-44. 2003..The VTEC and their toxicity are considered as a paradigm for emerging pathogens. The question on how such pathogens could arise from a basic commensal population is also addressed...
- Escherichia coli 'O' group serological responses and clinical correlations in epidemic HUS patientsHemant Kulkarni
Department of Nephrology, Women s and Children s Hospital, North Adelaide, SA, Australia
Comp Immunol Microbiol Infect Dis 25:249-68. 2002..This study indicates that co-infection with different VTEC serogroups may affect clinical outcome...
- Verocytotoxigenic Escherichia coli serologic responses in patients with hemolytic uremic syndromePaul N Goldwater
J Infect Dis 186:582; author reply 582-3. 2002
- Virulence properties and serotypes of Shiga toxin-producing Escherichia coli from healthy Australian cattleMichael A Hornitzky
Elizabeth Macarthur Agricultural Institute, New South Wales Agriculture, Camden, Australia
Appl Environ Microbiol 68:6439-45. 2002..The second, a longitudinal study of three feedlots and five pasture beef properties, resulted in the recovery of 118 cSTEC isolates from 104 animals. Of the 70 serotypes identified, 38 had not previously been reported...
- Antibiotic resistance among verocytotoxigenic Escherichia coli (VTEC) and non-VTEC isolated from domestic animals and humansKarl A Bettelheim
Microbiological Diagnostic Unit, Public Health Laboratory, Department of Microbiology and Immunology, University of Melbourne, Royal Parade, Parkville, Victoria, Australia 3052
J Med Microbiol 52:155-62. 2003....
- stx1c Is the most common Shiga toxin 1 subtype among Shiga toxin-producing Escherichia coli isolates from sheep but not among isolates from cattleKim N Brett
Cooperative Research Centre for Cattle and Beef Quality, Elizabeth Macarthur Agricultural Institute, Camden, New South Wales 2570, Australia
J Clin Microbiol 41:926-36. 2003....
- Infection and food: a factor in sudden infant death syndrome?Jane L Pearce
Department of Agricultural Sciences, Faculty of Science, Technology and Engineering, La Trobe University, Victoria 3086, Australia
FEMS Immunol Med Microbiol 42:66-75. 2004..In this ecological study, we demonstrated significant correlations between SIDS rates and exposure to meat from some sources, and we propose that more detailed studies be carried out...
- Outbreak of Shiga toxin-producing Escherichia coli O111:H8 infectionKarl A Bettelheim
Clin Infect Dis 39:148; author reply 148-9. 2004
- Isolation of Escherichia coli O5 :H-, possessing genes for Shiga toxin 1, intimin-beta and enterohaemolysin, from an intestinal biopsy from an adult case of bloody diarrhoea: evidence for two distinct O5 :H- pathotypesCatriona McLean
Department of Pathology, Alfred Hospital, Prahran, Victoria 3181, Australia
J Med Microbiol 54:605-7. 2005..Both were biochemically typical Escherichia coli O5 :H(-), apart from producing urease. Such O5 isolates represent a human pathogenic E. coli lineage...
- Curliated Escherichia coli, soluble curlin and the sudden infant death syndrome (SIDS)Paul N Goldwater
J Med Microbiol 51:1009-12. 2002
- First isolation outside Europe of sorbitol-fermenting verocytotoxigenic Escherichia coli (VTEC) belonging to O group O157Karl A Bettelheim
J Med Microbiol 51:713-4. 2002
- HEp-2 cell adherence, actin aggregation, and intimin types of attaching and effacing Escherichia coli strains isolated from healthy infants in Germany and AustraliaLothar Beutin
Division of Emerging Bacterial Pathogens, Department of Biological Safety, Robert Koch Institute, 13353 Berlin, Germany
Infect Immun 71:3995-4002. 2003..Our finding indicates that atypical EPEC strains could play a double role as strains that naturally immunize against intimin in humans and as reservoirs for new emerging human pathogenic EPEC strains...
- Role of Non-O157:H7 Escherichia coli in hemolytic uremic syndromePaul N Goldwater
Clin Infect Dis 35:346-7. 2002