Oliver Fleck

Summary

Country: UK

Publications

  1. Villahermosa D, Christensen O, Knapp K, Fleck O. Schizosaccharomyces pombe MutS? and MutL? Maintain Stability of Tetra-Nucleotide Repeats and Msh3 of Hepta-Nucleotide Repeats. G3 (Bethesda). 2017;7:1463-1473 pubmed publisher
    ..We conclude that Msh3 has no obvious function in MMR in S. pombe, but contributes to DNA repeat stability in MMR-independent processes. ..
  2. Fleck O, Fahnøe U, Løvschal K, Gasasira M, Marinova I, Kragelund B, et al. Deoxynucleoside Salvage in Fission Yeast Allows Rescue of Ribonucleotide Reductase Deficiency but Not Spd1-Mediated Inhibition of Replication. Genes (Basel). 2017;8: pubmed publisher
    ..We propose that this inhibition works at the point of the replication clamp proliferating cell nuclear antigen, a co-factor for DNA replication. ..
  3. Villahermosa D, Knapp K, Fleck O. A mutated dph3 gene causes sensitivity of Schizosaccharomyces pombe cells to cytotoxic agents. Curr Genet. 2017;63:1081-1091 pubmed publisher
    ..This is likely mediated by efficient translation of proteins in response to DNA damage and replication stress. ..
  4. Villahermosa D, Fleck O. Elp3 and Dph3 of Schizosaccharomyces pombe mediate cellular stress responses through tRNALysUUU modifications. Sci Rep. 2017;7:7225 pubmed publisher