Naomi A Fineberg

Summary

Country: UK

Publications

  1. ncbi request reprint Obsessive-compulsive disorder: boundary issues
    Naomi A Fineberg
    Postgraduate School of Medicine, University of Hertfordshire, Gueen Elizabeth II Hospital, Welwyn Garden City, UK
    CNS Spectr 12:359-64, 367-375. 2007
  2. ncbi request reprint Sustained response versus relapse: the pharmacotherapeutic goal for obsessive-compulsive disorder
    Naomi A Fineberg
    Postgraduate School of Medicine, University of Hertfordshire, Hatfield, Herts, UK
    Int Clin Psychopharmacol 22:313-22. 2007
  3. doi request reprint Evidence-based pharmacotherapy of obsessive-compulsive disorder
    Naomi A Fineberg
    Mental Health Unit, QEII Hospital, Welwyn Garden City, Hertfordshire, UK
    Int J Neuropsychopharmacol 15:1173-91. 2012
  4. ncbi request reprint Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: a meta-analysis of randomized controlled treatment trials
    Naomi A Fineberg
    Hertfordshire Partnership NHS Trust, UK
    Int Clin Psychopharmacol 21:337-43. 2006
  5. pmc Probing compulsive and impulsive behaviors, from animal models to endophenotypes: a narrative review
    Naomi A Fineberg
    Department of Psychiatry, National OCDs Specialist Centre, Hertfordshire Partnership NHS Foundation Trust, Queen Elizabeth II Hospital, Welwyn Garden City, Hertfordshire, UK
    Neuropsychopharmacology 35:591-604. 2010
  6. ncbi request reprint Escitalopram prevents relapse of obsessive-compulsive disorder
    Naomi A Fineberg
    Postgraduate Medical School, University of Hertfordshire, Hatfield, United Kingdom
    Eur Neuropsychopharmacol 17:430-9. 2007
  7. ncbi request reprint A review of antipsychotics in the treatment of obsessive compulsive disorder
    Naomi A Fineberg
    Department of Psychiatry, Queen Elizabeth II Hospital, Welwyn Garden City, Hertfordshire, UK
    J Psychopharmacol 20:97-103. 2006
  8. ncbi request reprint Adding quetiapine to SRI in treatment-resistant obsessive-compulsive disorder: a randomized controlled treatment study
    Naomi A Fineberg
    Department of Psychiatry, Mental Health Unit, Queen Elizabeth II Hospital, Howlands, Hertfordshire, Welwyn Garden City, UK
    Int Clin Psychopharmacol 20:223-6. 2005
  9. ncbi request reprint Evidence-based pharmacotherapy of obsessive-compulsive disorder
    Naomi A Fineberg
    Department of Psychiatry, Queen Elizabeth II Hospital, Welwyn Garden City, UK
    Int J Neuropsychopharmacol 8:107-29. 2005
  10. doi request reprint Response perseveration in stimulant dependence is associated with striatal dysfunction and can be ameliorated by a D(2/3) receptor agonist
    Karen D Ersche
    Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
    Biol Psychiatry 70:754-62. 2011

Detail Information

Publications34

  1. ncbi request reprint Obsessive-compulsive disorder: boundary issues
    Naomi A Fineberg
    Postgraduate School of Medicine, University of Hertfordshire, Gueen Elizabeth II Hospital, Welwyn Garden City, UK
    CNS Spectr 12:359-64, 367-375. 2007
    ..Studies designed to delineate the cause, consequences, and common factors are a challenging but essential goal for future research in this area...
  2. ncbi request reprint Sustained response versus relapse: the pharmacotherapeutic goal for obsessive-compulsive disorder
    Naomi A Fineberg
    Postgraduate School of Medicine, University of Hertfordshire, Hatfield, Herts, UK
    Int Clin Psychopharmacol 22:313-22. 2007
    ..Viewed collectively, these results suggest that selective serotonin reuptake inhibitors are effective long-term treatments and relapse prevention represents the treatment target for obsessive-compulsive disorder...
  3. doi request reprint Evidence-based pharmacotherapy of obsessive-compulsive disorder
    Naomi A Fineberg
    Mental Health Unit, QEII Hospital, Welwyn Garden City, Hertfordshire, UK
    Int J Neuropsychopharmacol 15:1173-91. 2012
    ..Newer compounds targeting other neurotransmitter systems, such as glutamate, are undergoing evaluation...
  4. ncbi request reprint Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: a meta-analysis of randomized controlled treatment trials
    Naomi A Fineberg
    Hertfordshire Partnership NHS Trust, UK
    Int Clin Psychopharmacol 21:337-43. 2006
    ..008), the clinical significance of which was limited by between-study heterogeneity. The mechanism underlying the effect may involve serotonin and/or dopamine neurotransmission...
  5. pmc Probing compulsive and impulsive behaviors, from animal models to endophenotypes: a narrative review
    Naomi A Fineberg
    Department of Psychiatry, National OCDs Specialist Centre, Hertfordshire Partnership NHS Foundation Trust, Queen Elizabeth II Hospital, Welwyn Garden City, Hertfordshire, UK
    Neuropsychopharmacology 35:591-604. 2010
    ..Targeted application of neurocognitive tasks, receptor-specific neurochemical probes, and brain systems neuroimaging techniques have potential for future research in this field...
  6. ncbi request reprint Escitalopram prevents relapse of obsessive-compulsive disorder
    Naomi A Fineberg
    Postgraduate Medical School, University of Hertfordshire, Hatfield, United Kingdom
    Eur Neuropsychopharmacol 17:430-9. 2007
    ..These results demonstrate that escitalopram is effective for long-term treatment and relapse prevention in OCD...
  7. ncbi request reprint A review of antipsychotics in the treatment of obsessive compulsive disorder
    Naomi A Fineberg
    Department of Psychiatry, Queen Elizabeth II Hospital, Welwyn Garden City, Hertfordshire, UK
    J Psychopharmacol 20:97-103. 2006
  8. ncbi request reprint Adding quetiapine to SRI in treatment-resistant obsessive-compulsive disorder: a randomized controlled treatment study
    Naomi A Fineberg
    Department of Psychiatry, Mental Health Unit, Queen Elizabeth II Hospital, Howlands, Hertfordshire, Welwyn Garden City, UK
    Int Clin Psychopharmacol 20:223-6. 2005
    ..Larger studies are needed to explore the efficacy of second generation antipsychotics, such as quetiapine, when used as adjunct treatment in resistant OCD...
  9. ncbi request reprint Evidence-based pharmacotherapy of obsessive-compulsive disorder
    Naomi A Fineberg
    Department of Psychiatry, Queen Elizabeth II Hospital, Welwyn Garden City, UK
    Int J Neuropsychopharmacol 8:107-29. 2005
    ..This paper reviews the key questions related to OCD pharmacotherapy, synthesizing evidence derived from randomized controlled trials, meta-analyses and consensus guidelines...
  10. doi request reprint Response perseveration in stimulant dependence is associated with striatal dysfunction and can be ameliorated by a D(2/3) receptor agonist
    Karen D Ersche
    Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
    Biol Psychiatry 70:754-62. 2011
    ..The aim of this study was to measure behavioral and neural markers of compulsivity in stimulant-dependent individuals and to test whether these markers could be modulated by treatment with drugs targeting the dopamine system...
  11. ncbi request reprint A neuropsychological comparison of obsessive-compulsive disorder and trichotillomania
    Samuel R Chamberlain
    Department of Psychiatry, University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Cambridge, UK
    Neuropsychologia 45:654-62. 2007
    ..However, the extent to which these disorders share a common cognitive phenotype has yet to be elucidated using patients without confounding co-morbidities...
  12. ncbi request reprint Motor inhibition and cognitive flexibility in obsessive-compulsive disorder and trichotillomania
    Samuel R Chamberlain
    Department of Psychiatry, University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Box 189, Cambridge, UK
    Am J Psychiatry 163:1282-4. 2006
    ..The authors assessed and compared motor inhibition and cognitive flexibility in OCD and trichotillomania for the first time, to their knowledge...
  13. pmc Grey matter abnormalities in trichotillomania: morphometric magnetic resonance imaging study
    Samuel R Chamberlain
    Department of Psychiatry, University of Cambridge, Cambridge CB2 2QQ, UK
    Br J Psychiatry 193:216-21. 2008
    ..Trichotillomania (repetitive hair-pulling) is an Axis I psychiatric disorder whose neurobiological basis is incompletely understood. Whole-brain trichotillomania neuroimaging studies are lacking...
  14. doi request reprint Pharmacotherapy of obsessive-compulsive disorder: evidence-based treatment and beyond
    Naomi A Fineberg
    1Mental Health Unit, Hertfordshire Partnership Foundation Trust, Queen Elizabeth II Hospital, Welwyn Garden City, UK
    Aust N Z J Psychiatry 47:121-41. 2013
    ..Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder associated with a significant degree of functional disability and poor quality of life. Pharmacotherapy may have a substantial impact on the course and outcome of OCD...
  15. ncbi request reprint Clinical screening for obsessive-compulsive and related disorders
    Naomi A Fineberg
    National OCD Treatment Service, Queen Elizabeth II Hospital, Welwyn Garden City, Hertfordshire, UK
    Isr J Psychiatry Relat Sci 45:151-63. 2008
    ..Increased prevalence of OCDs is also reported to occur in certain secondary health-care settings. Better identification and treatment of OCDs are increasingly recognized as important public health priorities...
  16. doi request reprint Remission of obsessive-compulsive disorders and syndromes; evidence from a prospective community cohort study over 30 years
    Naomi A Fineberg
    National Obsessive Compulsive Disorders Specialist Service, Hertfordshire Partnership NHS Foundation Trust, Queen Elizabeth II Hospital, Welwyn Garden City, Hertfordshire, UK
    Int J Psychiatry Clin Pract 17:179-87. 2013
    ..However, roughly one-third of OCD cases do not remit by 50 years of age. ..
  17. ncbi request reprint Does obsessive-compulsive personality disorder belong within the obsessive-compulsive spectrum?
    Naomi A Fineberg
    Postgraduate School of Medicine, University of Hertfordshire, Queen Elizabeth II Hospital, Welwyn Garden City, UK
    CNS Spectr 12:467-82. 2007
    ..By viewing OCPD as a candidate member of the obsessive-compulsive spectrum, we gain a fresh approach to understanding its neurobiology, etiology, and potential treatments...
  18. doi request reprint Impaired visuospatial associative memory and attention in obsessive compulsive disorder but no evidence for differential dopaminergic modulation
    Sharon Morein-Zamir
    Department of Psychiatry, University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Hills Road, Box 189, CB2 2QQ, Cambridge, UK
    Psychopharmacology (Berl) 212:357-67. 2010
    ..Patients with obsessive compulsive disorder (OCD) demonstrate impaired cognition in some selected domains. Although serotoninergic dysfunction has been implicated in OCD, recent evidence suggests that dopamine may play a role as well...
  19. doi request reprint Orbitofrontal dysfunction in patients with obsessive-compulsive disorder and their unaffected relatives
    Samuel R Chamberlain
    Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Box 189, Cambridge CB2 0QQ, UK
    Science 321:421-2. 2008
    ....
  20. doi request reprint Lifetime comorbidity of obsessive-compulsive disorder and sub-threshold obsessive-compulsive symptomatology in the community: impact, prevalence, socio-demographic and clinical characteristics
    Naomi A Fineberg
    National Obsessive Compulsive Disorders Specialist Service, Hertfordshire Partnership NHS Foundation Trust, Queen Elizabeth II Hospital, Welwyn Garden City, Hertfordshire, UK
    Int J Psychiatry Clin Pract 17:188-96. 2013
    ..Conclusions. Despite the statistical limitations imposed by the small sample-size, our findings highlight the negative impact of psychiatric comorbidity on health and psychosocial function. ..
  21. pmc Strategy implementation in obsessive-compulsive disorder and trichotillomania
    Samuel R Chamberlain
    Department of Psychiatry, University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Cambridge, UK
    Psychol Med 36:91-7. 2006
    ....
  22. doi request reprint Cognitive Assessment Instrument of Obsessions and Compulsions (CAIOC-13) - a new 13-item scale for evaluating functional impairment associated with OCD
    Winand H Dittrich
    Department of Psychology, University of Hertfordshire, Hatfield, AL10 9AB, UK
    Psychiatry Res 187:283-90. 2011
    ..Further validation, including research into the relationship of the CAIOC-13 with laboratory measures of cognitive impairment and evaluation of its sensitivity is indicated...
  23. doi request reprint Trichotillomania: neurobiology and treatment
    Samuel R Chamberlain
    Department of Psychiatry, University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Cambridge, UK
    Neurosci Biobehav Rev 33:831-42. 2009
    ..Finally, we highlight important areas for future neurobiological and treatment research...
  24. ncbi request reprint Are placebo-controlled trials still important for obsessive compulsive disorder?
    Naomi A Fineberg
    Department of Psychiatry, Queen Elizabeth II Hospital, Welwyn Garden City, Herts, UK
    Prog Neuropsychopharmacol Biol Psychiatry 30:413-22. 2006
    ..In this paper we examine arguments for and against the ongoing use of placebo agents in the development of new treatments for obsessive compulsive disorder in the context of evidence from randomised controlled trials...
  25. ncbi request reprint Comorbid depression in obsessive compulsive disorder (OCD): symptomatic differences to major depressive disorder
    Naomi A Fineberg
    Department of Psychiatry, QE II Hospital, Howlands, Welwyn Garden City, Hertfordshire, AL7 4HQ, UK
    J Affect Disord 87:327-30. 2005
    ..We discuss these findings in the context of neurobiological bases for the two disorders...
  26. doi request reprint A prospective population-based cohort study of the prevalence, incidence and impact of obsessive-compulsive symptomatology
    Naomi A Fineberg
    Department of Psychiatry, National OCD Specialist Service, Hertfordshire Partnership NHS Foundation Trust, Queen Elizabeth II Hospital, Welwyn Garden City, UK
    Int J Psychiatry Clin Pract 17:170-8. 2013
    ..Conclusions. Clinically-relevant OC syndromes start early and are associated with substantial distress, treatment-seeking activity and in the case of OCD, functional disability. ..
  27. ncbi request reprint Is there place for placebo controlled trials in the treatment of affective disorders?
    Naomi A Fineberg
    Rev Bras Psiquiatr 28:89-90. 2006
  28. ncbi request reprint Lifting the veil on trichotillomania
    Samuel R Chamberlain
    Department of Psychiatry, University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Box 189, Cambridge, CB2 2QQ UK
    Am J Psychiatry 164:568-74. 2007
  29. ncbi request reprint Which antidepressants have demonstrated superior efficacy? A review of the evidence
    Stuart A Montgomery
    Imperial College School of Medicine, University of London, UK
    Int Clin Psychopharmacol 22:323-9. 2007
    ..This review of published data found evidence that only a very few antidepressants are shown to be more effective than others...
  30. ncbi request reprint Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology
    David S Baldwin
    Division of Clinical Neurosciences, University of Southampton, Southampton, UK
    J Psychopharmacol 19:567-96. 2005
    ..The guidelines cover the diagnosis of anxiety disorders and key steps in clinical management, including acute treatment, relapse prevention and approaches for patients who do not respond to first-line treatments...
  31. doi request reprint OCD and anxiety: from afterthought to independence
    Kevin J Craig
    J Psychopharmacol 22:217-9. 2008
  32. ncbi request reprint Delayed sleep phase in severe obsessive-compulsive disorder: a systematic case-report survey
    Suman Mukhopadhyay
    Hillingdon Hospital, Middlesex, UK
    CNS Spectr 13:406-13. 2008
    ..To study the prevalence of delayed sleep phase (DSP) in a cohort of inpatients with severe obsessive-compulsive disorder (OCD) and to identify clinical and demographic correlates...
  33. pmc Impaired cognitive flexibility and motor inhibition in unaffected first-degree relatives of patients with obsessive-compulsive disorder
    Samuel R Chamberlain
    Department of Psychiatry, University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Box 189, Cambridge, CB2 2QQ UK
    Am J Psychiatry 164:335-8. 2007
    ..The aim was to assess inhibitory control processes in unaffected first-degree relatives of OCD patients for the first time with objective tests...
  34. ncbi request reprint How common is obsessive-compulsive disorder in a dermatology outpatient clinic?
    Naomi A Fineberg
    Hertfordshire Partnership, NHS Trust, London, UK
    J Clin Psychiatry 64:152-5. 2003
    ..This study was prompted by reports suggesting a high prevalence of unrecognized obsessive-compulsive disorder (OCD) in the dermatology clinic...