I Eardley

Summary

Country: UK

Publications

  1. ncbi request reprint Pharmacotherapy for erectile dysfunction
    Harin Padma-Nathan
    J Sex Med 1:128-40. 2004
  2. doi request reprint Workplace-based assessment in surgical training: experiences from the Intercollegiate Surgical Curriculum Programme
    Ian Eardley
    ISCP, Sydney, New South Wales, Australia
    ANZ J Surg 83:448-53. 2013
  3. ncbi request reprint An open-label, randomized, flexible-dose, crossover study to assess the comparative efficacy and safety of sildenafil citrate and apomorphine hydrochloride in men with erectile dysfunction
    I Eardley
    Pyrah Department of Urology, St James s University Hospital, Leeds, UK
    BJU Int 93:1271-5. 2004
  4. ncbi request reprint The sexual habits of British men and women over 40 years old
    I Eardley
    St James s Hospital, Leeds, UK
    BJU Int 93:563-7. 2004
  5. ncbi request reprint Imaging for erectile dysfunction
    Ian Eardley
    St James s University Hospital, Leeds, UK
    Curr Opin Urol 12:143-7. 2002
  6. doi request reprint Pharmacotherapy for erectile dysfunction
    Ian Eardley
    Department of Urology, St James University Hospital, Leeds, UK
    J Sex Med 7:524-40. 2010
  7. ncbi request reprint Vardenafil: a new oral treatment for erectile dysfunction
    I Eardley
    St James University Hospital, Leeds, UK
    Int J Clin Pract 58:801-6. 2004
  8. ncbi request reprint Efficacy and safety of tadalafil in a Western European population of men with erectile dysfunction
    Ian Eardley
    Department of Urology, St James University Hospital, Leeds, West Yorkshire, UK
    BJU Int 94:871-7. 2004
  9. doi request reprint Global experiences with vardenafil in men with erectile dysfunction and underlying conditions
    I Eardley
    Pyrah Department of Urology, St James s University Hospital, Leeds, UK
    Int J Clin Pract 62:1594-603. 2008
  10. ncbi request reprint An open-label, multicentre, randomized, crossover study comparing sildenafil citrate and tadalafil for treating erectile dysfunction in men naïve to phosphodiesterase 5 inhibitor therapy
    Ian Eardley
    St James University Hospital, Pyrah Department of Urology, Leeds, UK
    BJU Int 96:1323-32. 2005

Detail Information

Publications49

  1. ncbi request reprint Pharmacotherapy for erectile dysfunction
    Harin Padma-Nathan
    J Sex Med 1:128-40. 2004
    ..Advances in understanding of the biochemistry and physiology of penile erection have led to breakthroughs in pharmacotherapy of erectile dysfunction...
  2. doi request reprint Workplace-based assessment in surgical training: experiences from the Intercollegiate Surgical Curriculum Programme
    Ian Eardley
    ISCP, Sydney, New South Wales, Australia
    ANZ J Surg 83:448-53. 2013
    ..The principle assessments used were Case-based Discussion, Procedure-based Assessments (PBA), Direct Observation of Procedural Skills, and Clinical Evaluation Exercise and a Multisource Feedback tool...
  3. ncbi request reprint An open-label, randomized, flexible-dose, crossover study to assess the comparative efficacy and safety of sildenafil citrate and apomorphine hydrochloride in men with erectile dysfunction
    I Eardley
    Pyrah Department of Urology, St James s University Hospital, Leeds, UK
    BJU Int 93:1271-5. 2004
    ..To compare the efficacy and safety of sildenafil and apomorphine in the treatment of men with erectile dysfunction (ED)...
  4. ncbi request reprint The sexual habits of British men and women over 40 years old
    I Eardley
    St James s Hospital, Leeds, UK
    BJU Int 93:563-7. 2004
    ..To obtain a greater understanding of sexual behaviour and habits among men with and without erectile dysfunction (ED), and their female partners, to improve the management of ED in heterosexual men...
  5. ncbi request reprint Imaging for erectile dysfunction
    Ian Eardley
    St James s University Hospital, Leeds, UK
    Curr Opin Urol 12:143-7. 2002
    ..In addition, the new techniques of functional magnetic resonance imaging and positron emission tomography scanning are beginning to offer new insights into the central mechanisms which control erections...
  6. doi request reprint Pharmacotherapy for erectile dysfunction
    Ian Eardley
    Department of Urology, St James University Hospital, Leeds, UK
    J Sex Med 7:524-40. 2010
    ..Pharmacotherapy is the usual initial therapy for most men with erectile dysfunction...
  7. ncbi request reprint Vardenafil: a new oral treatment for erectile dysfunction
    I Eardley
    St James University Hospital, Leeds, UK
    Int J Clin Pract 58:801-6. 2004
    ..It is well tolerated with a side effect profile typical of this class of drugs. It has a rapid onset of action and has demonstrable efficacy for men using the medication for up to 2 years...
  8. ncbi request reprint Efficacy and safety of tadalafil in a Western European population of men with erectile dysfunction
    Ian Eardley
    Department of Urology, St James University Hospital, Leeds, West Yorkshire, UK
    BJU Int 94:871-7. 2004
    ....
  9. doi request reprint Global experiences with vardenafil in men with erectile dysfunction and underlying conditions
    I Eardley
    Pyrah Department of Urology, St James s University Hospital, Leeds, UK
    Int J Clin Pract 62:1594-603. 2008
    ..The present review aims to summarise and discuss the available evidence for the efficacy, safety and tolerability of vardenafil in patients with underlying conditions including diabetes, hypertension and dyslipidaemia...
  10. ncbi request reprint An open-label, multicentre, randomized, crossover study comparing sildenafil citrate and tadalafil for treating erectile dysfunction in men naïve to phosphodiesterase 5 inhibitor therapy
    Ian Eardley
    St James University Hospital, Pyrah Department of Urology, Leeds, UK
    BJU Int 96:1323-32. 2005
    ..To compare treatment preference, efficacy, and tolerability of sildenafil citrate (sildenafil) and tadalafil for treating erectile dysfunction (ED) in men naïve to phosphodiesterase 5 (PDE5) inhibitor therapy...
  11. ncbi request reprint The multinational Men's Attitudes to Life Events and Sexuality study: the influence of diabetes on self-reported erectile function, attitudes and treatment-seeking patterns in men with erectile dysfunction
    I Eardley
    Pyrah Department of Urology, St James University Hospital, Leeds, UK
    Int J Clin Pract 61:1446-53. 2007
    ..To identify the prevalence of erectile dysfunction (ED) in men with diabetes, and to compare the perceptions of ED and the treatment-seeking behaviour of these men with men with ED without diabetes...
  12. ncbi request reprint Vardenafil improves erectile function in men with erectile dysfunction and associated underlying conditions, irrespective of the use of concomitant medications
    Ian Eardley
    Pyrah Department of Urology, St James s University Hospital, Leeds, UK
    J Sex Med 7:244-55. 2010
    ..Men with erectile dysfunction (ED) are also likely to have associated underlying conditions...
  13. ncbi request reprint Impairment of corpus cavernosal smooth muscle relaxation by glycosylated human haemoglobin
    J J Cartledge
    Pyrah Department of Urology, St James s University Hospital, Leeds, UK
    BJU Int 85:735-41. 2000
    ....
  14. ncbi request reprint Endothelial and neuronal-derived nitric oxide mediated relaxation of corpus cavernosal smooth muscle in a rat, in vitro, model of erectile function
    J J Cartledge
    Pyrah Department of Urology, St James s University Hospital, Leeds, UK
    Int J Impot Res 12:213-21. 2000
    ..In conclusion, the inhibitory, relaxant stimulus of rat corpora cavernosa is due to both neuronal nitric oxide and endothelial-derived nitric oxide released in response to cholinergic stimulation...
  15. ncbi request reprint Nitric oxide-mediated corpus cavernosal smooth muscle relaxation is impaired in ageing and diabetes
    J J Cartledge
    Pyrah Department of Urology, St James s University Hospital, Leeds, UK
    BJU Int 87:394-401. 2001
    ....
  16. ncbi request reprint The role of nitric oxide in penile erection
    J Cartledge
    The Pyrah Department of Urology, St James s University Hospital, Beckett Street, Leeds, LS18 4AW, UK
    Expert Opin Pharmacother 2:95-107. 2001
    ..This review examines the role of NO in the penis in detail. Established and new treatments for erectile dysfunction whose effects are mediated via manipulation of the NO pathway are also described...
  17. ncbi request reprint Efficacy and safety of sildenafil citrate in the treatment of men with mild to moderate erectile dysfunction
    I Eardley
    Department of Urology, Leeds General Infirmary, Leeds LS1 3EX, UK
    Br J Psychiatry 178:325-30. 2001
    ..0001). There were no discontinuations due to sildenafil treatment. CONCLUSIONS: Sildenafil is effective and well tolerated in men with mild to moderate erectile dysfunction of no clinically identifiable organic cause...
  18. ncbi request reprint Factors associated with preference for sildenafil citrate and tadalafil for treating erectile dysfunction in men naïve to phosphodiesterase 5 inhibitor therapy: post hoc analysis of data from a multicentre, randomized, open-label, crossover study
    Ian Eardley
    Pyrah Department of Urology, St James University Hospital, Becket Street, Leeds, UK
    BJU Int 100:122-9. 2007
    ....
  19. doi request reprint Differences in side-effect duration and related bother levels between phosphodiesterase type 5 inhibitors
    Joby Taylor
    Department of Urology, York District Hospital, York, UK
    BJU Int 103:1392-5. 2009
    ....
  20. ncbi request reprint Advanced glycation end-products are responsible for the impairment of corpus cavernosal smooth muscle relaxation seen in diabetes
    J J Cartledge
    Pyrah Department of Urology, St James s University Hospital, Leeds, UK
    BJU Int 87:402-7. 2001
    ..To determine if advanced glycation end-products (AGEs) are responsible for the lower neuronal and endothelial-derived nitric oxide (NO)-mediated relaxation of corpus cavernosum in tissue in diabetic rats than in control rats...
  21. ncbi request reprint Tadalafil (Cialis) for men with erectile dysfunction
    I Eardley
    Department of Urology, St James University Hospital, Leeds, UK
    Int J Clin Pract 56:300-4. 2002
    ..Tadalafil is effective in the treatment of men with erectile dysfunction, and it appears to have a relatively mild side-effect profile, with no visual side-effects noted...
  22. ncbi request reprint The pathophysiological role of prostaglandins in penile erection
    S Minhas
    Pyrah Department of Urology, St James's University Hospital, Leeds, UK
    Expert Opin Pharmacother 2:799-811. 2001
    ....
  23. ncbi request reprint What is the relationship between male sexual function and lower urinary tract symptoms (LUTS)?
    S C Sak
    Department of Urology, St James University Hospital, Beckett Street, Leeds LS9 7TF, UK
    Eur Urol 46:482-7. 2004
    ..This observational study, performed in a single centre, seeks to explore this area further...
  24. ncbi request reprint Sildenafil
    J Cartledge
    Pyrah Department of Urology, St James University Hospital, Beckett Street, Leeds, LS9 7TF, UK
    Expert Opin Pharmacother 1:137-47. 1999
    ..These side effects are dose-dependent and well-tolerated. The introduction of sildenafil in many countries around the world has revolutionised the assessment and treatment of men with ED...
  25. ncbi request reprint A randomized double-blind placebo-controlled crossover trial of the efficacy of L-arginine in the treatment of interstitial cystitis
    J J Cartledge
    Pyrah Department of Urology, St James s University Hospital, Leeds, UK
    BJU Int 85:421-6. 2000
    ....
  26. pmc Onset and duration of action of sildenafil for the treatment of erectile dysfunction
    Ian Eardley
    Department of Urology, St James University Hospital, Leeds, West Yorkshire and Pfizer Ltd, Sandwich, Kent, UK
    Br J Clin Pharmacol 53:61S-65S. 2002
    ..To determine the onset and duration of action of sildenafil in patients with erectile dysfunction (ED)...
  27. ncbi request reprint The efficacy of tadalafil in clinical populations
    Ronald W Lewis
    Department of Urology, Medical College of Georgia, Augusta, GA 30912, USA, and St James University Hospital, Leeds, UK
    J Sex Med 2:517-31. 2005
    ....
  28. ncbi request reprint The interaction of nitric oxide and prostaglandins in the control of corporal smooth muscle tone: evidence for production of a cyclooxygenase-derived endothelium-contracting factor
    S Minhas
    Department of Urology, St James University Hospital, Leeds, UK
    BJU Int 87:882-8. 2001
    ..Endothelium-dependent relaxation to ACh results in the dual production of NO and a cyclooxygenase-derived endothelium contracting factor which acts in opposition to NO; this factor is unlikely to act on PGH2/TXA2 receptors...
  29. pmc The implementation of European Association of Urology guidelines in the management of acute epididymo-orchitis
    Mary A E Garthwaite
    Pyrah Department of Urology, St James s University Hospital, Leeds, UK
    Ann R Coll Surg Engl 89:799-803. 2007
    ....
  30. ncbi request reprint The stability of free and bound prostate-specific antigen
    J J Cartledge
    Pyrah Department of Urology, The General Infirmary at Leeds, UK
    BJU Int 84:810-4. 1999
    ..To determine if the assay for free prostate specific antigen (fPSA) and the calculated ratio of fPSA to total PSA (f/tPSA) is stable in conditions likely to be met in routine clinical practice...
  31. ncbi request reprint The prevalence of newly diagnosed hyperlipidaemia in men with erectile dysfunction
    Nicholas J Smith
    Pyrah Department of Urology, St James s University Hospital, Leeds, West Yorkshire, UK
    BJU Int 100:357-61. 2007
    ....
  32. ncbi request reprint Improvement in erectile function on vardenafil treatment correlates with treatment satisfaction in both patients and their partners
    David Ralph
    Middlesex Hospital, London, UK
    BJU Int 100:130-6. 2007
    ....
  33. ncbi request reprint Editorial comment on: daily treatment with sildenafil reverses endothelial dysfunction and oxidative stress in an animal model of insulin resistance
    Ian Eardley
    Eur Urol 53:1280-1. 2008
  34. doi request reprint Erectile dysfunction and constructs of masculinity and quality of life in the multinational Men's Attitudes to Life Events and Sexuality (MALES) study
    Michael S Sand
    Bayer Schering Pharma AG, Wuppertal, Germany
    J Sex Med 5:583-94. 2008
    ..The Men's Attitudes to Life Events and Sexuality (MALES) study assessed the prevalence and correlates of erectile dysfunction, and examined men's attitudes and behavior in relation to this dysfunction...
  35. ncbi request reprint Effects of testosterone on erectile function: implications for the therapy of erectile dysfunction
    Farid Saad
    GBU Gynecology Andrology, Bayer Schering Pharma, Berlin, Germany
    BJU Int 99:988-92. 2007
    ..Thus, androgen treatment in hypogonadic patients, including those unresponsive to PDE-5 inhibitors, often results in an improvement of ED. Testosterone therapy is safe and convenient, while rapidly correcting low testosterone levels...
  36. ncbi request reprint Vardenafil restores erectile function to normal range in men with erectile dysfunction
    Harin Padma-Nathan
    Male Clinic, Beverly Hills, CA 90212, USA
    J Sex Med 4:152-61. 2007
    ..The ability of oral phosphodiesterase type 5 (PDE5) inhibitor therapy to restore erectile function to normal is an important attribute to men with erectile dysfunction (ED)...
  37. ncbi request reprint A 4-year update on the safety of sildenafil citrate (Viagra)
    Harin Padma-Nathan
    The Male Clinic, Keck School of Medicine at the University of Southern California School of Medicine, Beverly Hills, California, USA
    Urology 60:67-90. 2002
    ..Lastly, we review the specific effects on the visual system based on findings from studies conducted during drug development and post marketing...
  38. ncbi request reprint The multinational Men's Attitudes to Life Events and Sexuality (MALES) study: I. Prevalence of erectile dysfunction and related health concerns in the general population
    Raymond C Rosen
    Department of Psychiatry, Robert Wood Johnson Medical School, Pisctaway, NJ 08854, USA
    Curr Med Res Opin 20:607-17. 2004
    ....
  39. ncbi request reprint Vardenafil provides reliable efficacy over time in men with erectile dysfunction
    Francesco Montorsi
    Instituto San Raffaele, Milan, Italy
    Urology 64:1187-95. 2004
    ..To evaluate the reliability of vardenafil efficacy and tolerability within 12 weeks in a broad population of men with erectile dysfunction (ED)...
  40. ncbi request reprint Vardenafil is effective and well-tolerated for treating erectile dysfunction in a broad population of men, irrespective of age
    Francois Giuliano
    Department of Urology, CHU de Bicetre, AP HP, 78 rue du General Leclerc, 94272 Le Kremlin Bicêtre Cedex, France
    BJU Int 95:110-6. 2005
    ..To assess the efficacy and safety of vardenafil in the treatment of erectile dysfunction (ED) in men of different age groups...
  41. ncbi request reprint Penetration and maintenance of erection with vardenafil: a time-from-dosing analysis
    Luc Valiquette
    Service d Urologie, CHUM Hopital St Luc, Montreal, Quebec, Canada
    Can J Urol 12:2687-98; discussion 2699. 2005
    ....
  42. ncbi request reprint Time from dosing to sexual intercourse attempts in men taking tadalafil in clinical trials
    Ridwan Shabsigh
    Department of Urology, Columbia University, New York, NY 10032, USA
    BJU Int 96:857-63. 2005
    ....
  43. ncbi request reprint Sexual experience of female partners of men with erectile dysfunction: the female experience of men's attitudes to life events and sexuality (FEMALES) study
    William A Fisher
    Department of Psychology, Social Science Centre 6430, University of Western Ontario, London, Ontario, Canada N6A 5C2
    J Sex Med 2:675-84. 2005
    ..Much research has explored the experience of erectile dysfunction (ED) among men with ED, but far less attention has been paid to the perceptions and sexual experiences of the female partners of men with ED...
  44. ncbi request reprint Vardenafil improves erectile function in men with erectile dysfunction irrespective of disease severity and disease classification
    Craig Donatucci
    Duke University Medical Center, Durham, NC, USA
    J Sex Med 1:301-9. 2004
    ..This retrospective subgroup analysis assessed the effectiveness of vardenafil treatment in men with ED of different baseline severity and disease classification...
  45. ncbi request reprint The multinational Men's Attitudes to Life Events and Sexuality (MALES) Study Phase II: understanding PDE5 inhibitor treatment seeking patterns, among men with erectile dysfunction
    William A Fisher
    Department of Psychology, Social Science Centre 6430, University of Western Ontario, Canada
    J Sex Med 1:150-60. 2004
    ..The aim of Phase II of the Men's Attitudes to Life Events and Sexuality (MALES) Study is to explore PDE5 inhibitor treatment seeking among men with erectile dysfunction (ED)...
  46. ncbi request reprint Comparing vardenafil and sildenafil in the treatment of men with erectile dysfunction and risk factors for cardiovascular disease: a randomized, double-blind, pooled crossover study
    Eusebio Rubio-Aurioles
    Asociacion Mexicana para la Salud Sexual AC, Tlalpan, Mexico
    J Sex Med 3:1037-49. 2006
    ....
  47. ncbi request reprint Optimisation of PDE5 inhibitor therapy in men with erectile dysfunction: converting "non-responders" into "responders"
    Ian Eardley
    Eur Urol 50:31-3. 2006
  48. ncbi request reprint Penile size and the 'small penis syndrome'
    Kevan R Wylie
    Porterbrook Clinic, Sheffield Care Trust, Sheffield, UK
    BJU Int 99:1449-55. 2007
    ..A thorough assessment, normalizing the worry and then exploring the treatment options in detail with the man, is essential to allow the matter to be consolidated satisfactorily within the male ego...
  49. ncbi request reprint Premature ejaculation: the scope of the problem
    Tricia Barnes
    Tricia Barnes and Associates, London, United Kingdom
    J Sex Marital Ther 33:151-70. 2007
    ..The approach most likely to provide success is a combination of cognitive and sex therapy with a pharmacologic agent of proven efficacy that has an easy-to-follow dosing regimen...