Research Topics
| C D DeakinSummaryCountry: UK Publications
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Detail Information
Publications
A critical reassessment of ambulance service airway management in prehospital care: Joint Royal Colleges Ambulance Liaison Committee Airway Working Group, June 2008Charles D Deakin
South Central Ambulance Service, Southern House, Sparrowgrove, Otterbourne, UK
Emerg Med J 27:226-33. 2010....
Confusion between monophasic and biphasic defibrillatorsRichard J Green
Resuscitation 68:433-4. 2006
Prehospital randomised assessment of a mechanical compression device in cardiac arrest (PaRAMeDIC) trial protocolGavin D Perkins
Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK
Scand J Trauma Resusc Emerg Med 18:58. 2010....
Advances in defibrillationCharles D Deakin
Southampton University Hospital NHS Trust, Southampton, UK
Curr Opin Crit Care 17:231-5. 2011..The place of defibrillation in the chain of survival is paramount and this review covers advances in this aspect of resuscitation over the past 18 months...
Securing the prehospital airway: a comparison of laryngeal mask insertion and endotracheal intubation by UK paramedicsC D Deakin
Hampshire Ambulance Service NHS Trust, Highcroft, Romsey Road, Winchester SO22 5DH, UK
Emerg Med J 22:64-7. 2005..The recent introduction of a disposable laryngeal mask airway has provided paramedics with an alternative to endotracheal intubation. Time taken to secure the airway with each device was compared in patients undergoing elective surgery...
Changes in transthoracic impedance during sequential biphasic defibrillationCharles D Deakin
Shackleton Department of Anaesthetics, Southampton University Hospital NHS Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 78:141-5. 2008..The effect of sequential biphasic shocks on TTI is unknown. We therefore studied patients undergoing elective cardioversion using a biphasic waveform to establish whether this is a phenomenon seen in the clinical setting...
Post-shock myocardial stunning: a prospective randomised double-blind comparison of monophasic and biphasic waveformsCharles D Deakin
Shackleton Department of Anaesthetics, Southampton University Hospital NHS Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 68:329-33. 2006..We therefore hypothesised that earlier sodium channel activation would result in earlier restoration of the first sinus beat following elective DC cardioversion...
Does telephone triage of emergency (999) calls using Advanced Medical Priority Dispatch (AMPDS) with Department of Health (DH) call prioritisation effectively identify patients with an acute coronary syndrome? An audit of 42,657 emergency calls to HampshiC D Deakin
Hampshire Ambulance Service NHS Trust, Highcroft, Winchester, Hampshire, UK
Emerg Med J 23:232-5. 2006..We retrospectively examined patients with ACS to identify whether this triage tool had been able to allocate an appropriate emergency response...
Assessment of the quality of cardiopulmonary resuscitation following modification of a standard telephone-directed protocolCharles D Deakin
South Central Ambulance Service NHS Trust Hampshire Division, Highcroft, Romsey Road, Winchester SO22 5DH, and Department of Medical Physics and Engineering, Southampton University Hospitals NHS Trust, UK
Resuscitation 72:436-43. 2007..11.1 telephone instructions are limited in their ability to produce correctly performed basic life support. The current telephone instructions were modified in an attempt to improve areas of poor CPR performance...
Does compression-only cardiopulmonary resuscitation generate adequate passive ventilation during cardiac arrest?Charles D Deakin
South Central Ambulance Service NHS Trust Hampshire Division, Highcroft, Romsey Road, Winchester SO22 5DH, UK
Resuscitation 75:53-9. 2007..We measured passive ventilation during optimal chest compression to determine whether compression-only CPR provides adequate gas exchange during cardiac arrest...
Effects of international football matches on ambulance call profiles and volumes during the 2006 World CupCharles D Deakin
South Central Ambulance Service NHS Trust, Highcroft, Romsey Road, Winchester SO22 5DH, UK
Emerg Med J 24:405-7. 2007..The effects of the 2006 World Cup football matches on call volumes and profiles were analysed to understand how public events can influence demands on the ambulance service...
From agonal to output: An ECG history of a successful pre-hospital thoracotomyCharles D Deakin
South Central Ambulance Service NHS Trust Hampshire Division, Highcroft, Romsey Road, Winchester SO22 5DH, UK
Resuscitation 75:525-9. 2007..Continuous ECG monitoring during the procedure has allowed presentation of sequential ECGs recorded during the procedure...
Chronic illness masquerading as acute injury in pre-hospital careCharles D Deakin
South Central Ambulance Service NHS Trust, Highcroft, Romsey Road, Winchester SO22 5DH, UK
Resuscitation 76:465-7. 2008..The importance of past medical history and the incidence of co-morbidity in relation to pre-hospital care are discussed...
Is ambulance telephone triage using advanced medical priority dispatch protocols able to identify patients with acute stroke correctly?C D Deakin
South Central Ambulance Service NHS Trust, North Wing, Southern House, Sparrowgrove, Otterbourne, Hants, UK
Emerg Med J 26:442-5. 2009....
Prehospital advanced airway management by ambulance technicians and paramedics: is clinical practice sufficient to maintain skills?C D Deakin
South Central Ambulance Service NHS Trust, Hampshire Division, Sparrowgrove, Otterbourne, UK
Emerg Med J 26:888-91. 2009....
Does an advanced life support course give non-anaesthetists adequate skills to manage an airway?Charles D Deakin
Shackleton Department of Anaesthetics, Southampton University Hospital NHS Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 81:539-43. 2010..Does the ALS course give non-anaesthetists adequate skills to manage an airway during a cardiac arrest?..
Evaluation of telephone-cardiopulmonary resuscitation advice for paediatric cardiac arrestCharles D Deakin
South Central Ambulance Service, Southern House, Sparrowgrove, Otterbourne, Hampshire, UK
Resuscitation 81:853-6. 2010..We evaluated a current paediatric telephone protocol (AMPDS v11.1) to assess the effectiveness of verbal CPR instructions in paediatric cardiac arrest...
Prehospital end-tidal carbon dioxide concentration and outcome in major traumaCharles D Deakin
Helicopter Emergency Service, Royal London Hospital, Whitechapel, London, United Kingdom
J Trauma 57:65-8. 2004..Petco2 correlates with outcome after prehospital primary cardiac arrest, but association with outcome from prehospital trauma has not been established...
What is the optimal paddle force during paediatric external defibrillation?Charles D Deakin
Shackleton Department of Anaesthetics, Southampton University Hospital NHS Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 59:83-8. 2003..No study has yet established the optimal paddle force required to minimise TTI in children of different ages...
Is the orientation of the apical defibrillation paddle of importance during manual external defibrillation?Charles D Deakin
Shackleton Department of Anaesthetics, Southampton University Hospital NHS Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 56:15-8. 2003..This may theoretically result in a higher TTI than a longitudinal orientation because of poorer contact at the lateral paddle edges. We compared TTI with the apical paddle in both a transverse and longitudinal orientation...
Differential contribution of skin impedance and thoracic volume to transthoracic impedance during external defibrillationCharles D Deakin
Shackleton Department of Anaesthetics, Southampton University Hospital, N H S Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 60:171-4. 2004..The relative contribution of each mechanism is unknown...
Determining the optimal paddle force for external defibrillationCharles D Deakin
Shackleton Department of Anaesthetics, Southampton University Hospital NHS Trust, Southampton, United Kingdom
Am J Cardiol 90:812-3. 2002
How often should defibrillation pads be changed?: the effect of evaporative dryingC D Deakin
Department of Anaesthesia, Southampton University Hospitals NHS Trust, UK
Resuscitation 48:157-62. 2001..This study was carried out to assess the effect of evaporative drying of defibrillation pads on TTI...
Effects of respiratory gas composition on transthoracic impedanceC D Deakin
Department of Anaesthesia, Southampton University Hospitals NHS Trust, Southampton General Hospital, UK
Resuscitation 38:193-5. 1998..Therefore transthoracic current during defibrillation is unlikely to be affected by different respiratory gases. This is the first study to document that these respiratory gases do not change the impedance of transthoracic pathways...
A randomised controlled trial of the effect of biphasic or monophasic waveform on the incidence and severity of cutaneous burns following external direct current cardioversionJonathan J S Ambler
Shackleton Department of Anaesthetics, Southampton University Hospitals NHS Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 71:293-300. 2006..We designed a prospective randomised double-blinded controlled study to determine the effect of biphasic or monophasic waveform on the pain and inflammation occurring after elective cardioversion...
A prospective infant manikin-based observational study of telephone-cardiopulmonary resuscitationS Dawkins
South Central Ambulance Service NHS Trust Hampshire Division, Highcroft, Romsey Road, Winchester SO22 5DH, UK
Resuscitation 76:63-8. 2008..Little is known as to whether laypeople carrying out these instructions deliver effective CPR...
Are European Resuscitation Council recommendations for paddle force achievable during defibrillation?D M Sado
Shackleton Department of Anaesthetics, Southampton University Hospital NHS Trust, Tremona Road, SO16 6YD, Southampton, UK
Resuscitation 51:287-90. 2001..27) and dominant hand-grip strength (r2=0.34). The ERC recommendation of 12 kg paddle force is not achievable by the majority of defibrillator operators...
Does paddle force applied during defibrillation meet advanced life support guidelines of the European Resuscitation Council?C D Deakin
Shackleton Departments of Anaesthetics and Department of Medical Physics and Bioengineering, Southampton University Hospital, NHS Trust Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 48:301-3. 2001..to determine whether paddle force applied during defibrillation meets the 12 kg (approximately 120 N) force recommended by the advanced life support (ALS) guidelines of the European Resuscitation Council (ERC)...
Autotransfusion decreases blood usage following cardiac surgery -- a prospective randomized trialM J Dalrymple-Hay
Wessex Cardiothoracic Centre, Southampton, UK
Cardiovasc Surg 9:184-7. 2001..Transfusion reactions, infection risk and cost should stimulate us to decrease this transfusion rate. We tested the efficacy of autotransfusion of washed postoperative mediastinal fluid in a prospective randomized trial...
Methylene blue during cardiopulmonary bypass to treat refractory hypotension in septic endocarditisM Grayling
Shackleton Department of Anaesthesia, Southampton General Hospital, Southampton, United Kingdom
J Thorac Cardiovasc Surg 125:426-7. 2003
Do physiological changes in pregnancy change defibrillation energy requirements?J Nanson
Shackleton Department of Anaesthesia, Southampton University Hospital NHS Trust, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
Br J Anaesth 87:237-9. 2001..3 (15.8) Omega at term and 91.6 (11.8) Omega 6-8 weeks after delivery; the difference was not statistically significant. We conclude that current energy requirements for adult defibrillation are appropriate for use during pregnancy...
Reducing allogeneic transfusion in cardiac surgery: a randomized double-blind placebo-controlled trial of antifibrinolytic therapies used in addition to intra-operative cell salvageP Diprose
Department of Anaesthesia, Southampton University Hospitals, Southampton SO16 6YD, UK
Br J Anaesth 94:271-8. 2005..46; P<0.001). CONCLUSIONS: When used in addition to intra-operative cell salvage, aprotinin is the most efficacious pharmacological therapy for reducing patient exposure to any allogeneic transfusion during first-time cardiac surgery...
Evidence-based guidelines for the use of defibrillation padsN E Drury
Shackleton Department of Anaesthetics, Southampton University Hospitals NHS Trust, SO16 6YD, Southampton, UK
Resuscitation 51:283-6. 2001..CONCLUSIONS: Defibrillation pads can be used for up to 30 min without evaporation causing a clinically significant increase in TTI. The passage of a defibrillation current across pads does not further accelerate water loss...
The incidence and severity of cutaneous burns following external DC cardioversionJonathan J S Ambler
Shackleton Department of Anaesthetics, Southampton University Hospitals NHS Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 61:281-8. 2004..To reduce burns, operators should apply optimal paddle force equally to both paddles, with the paddles applied so as to provide even contact along their edges. Burns may also be minimised by starting with lower energy shocks...
A prospective manikin-based observational study of telephone-directed cardiopulmonary resuscitationSpencer Cheung
South Central Ambulance Service NHS Trust Hampshire Division, Highcroft, Romsey Road, Winchester SO22 5DH, and Department of Medical Physics and Engineering, Southampton University Hospitals NHS Trust, UK
Resuscitation 72:425-35. 2007..The effectiveness of this technique was examined in a manikin-based study...
Laryngopharyngeal pH measurementE J Spurrier
School of Medicine, Southampton University School of Medicine, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
Emerg Med J 21:493-4. 2004..This study assessed one technique for investigating the aspiration risk in ED patients. Cricoid pressure is used to reduce this risk and the technique may also examine this manoeuvre...
A randomized controlled trial of efficacy and ST change following use of the Welch-Allyn MRL PIC biphasic waveform versus damped sine monophasic waveform for external DC cardioversionJonathan J S Ambler
Shackleton Department of Anaesthetics, Southampton University Hospitals NHS Trust, Southampton SO16 6YD, UK
Resuscitation 71:146-51. 2006..No studies have investigated this effect on ST change with atrial arrhythmias. We studied the efficacy of the Welch Allyn-MRL PIC biphasic defibrillator...
Ambient oxygen concentrations resulting from use of the Lund University Cardiopulmonary Assist System (LUCAS) device during simulated cardiopulmonary resuscitationCharles D Deakin
South Central Ambulance Service NHS Trust, Highcroft, Romsey Road, Winchester SO22 5DH, UK
Resuscitation 74:303-9. 2007..This study used simulated CPR with a LUCAS device to measure resulting ambient oxygen concentrations and assess safety of the device...
Is optimal paddle force applied during paediatric external defibrillation?Sarah H Bennetts
Shackleton Department of Anaesthetics, Southampton University Hospital NHS Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 60:29-32. 2004..9 kgf, and for children >10 kg using adult paddles is 5.1 kgf. We compared defibrillation paddle force applied during simulated paediatric defibrillation with these optimal values...
Cardiopulmonary resuscitation following minimally invasive repair of pectus excavatum (Nuss technique)P Picton
Department of Anaesthesia, Southampton General Hospital, Tremona Road, Southampton S016 6YD, UK
Resuscitation 57:309-10. 2003
The effect of topical non-steroidal anti-inflammatory cream on the incidence and severity of cutaneous burns following external DC cardioversionJonathan J S Ambler
Shackleton Department of Anaesthetics, Southampton University Hospitals NHS Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 65:173-8. 2005..We designed a study to determine whether the application of non-steroidal anti-inflammatory cream prior to cardioversion reduces their incidence and severity...
The effect of prophylactic topical steroid cream on the incidence and severity of cutaneous burns following external DC cardioversionJonathan J S Ambler
Shackleton Department of Anaesthetics, Southampton University Hospitals NHS Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 65:179-84. 2005..We designed a prospective double-blinded controlled study to determine whether the application of steroid cream prior to cardioversion reduces their incidence and severity...
External defibrillation in the left lateral position--a comparison of manual paddles with self-adhesive padsTamsin E L Dodd
Shackleton Department of Anaesthetics, Southampton University Hospital NHS Trust, Tremona Road, Southampton SO166YD, UK
Resuscitation 63:283-6. 2004..0001). CONCLUSION: Despite the subjective difficulties of defibrillating patients in the AP position whilst leaning over them, use of manual paddles achieves a lower TTI than that achieved with self-adhesive pads...
Defibrillation during renal dialysis: a survey of UK practice and procedural recommendationsScott Bird
Shackleton Department of Anaesthetics, Southampton University Hospital N H S Trust, Tremona Road, Southampton SO16 6YD, UK
Resuscitation 73:347-53. 2007..Although national and international safety standards caution against defibrillating under this circumstance, it appears to be an area of confusion that we have investigated in more detail...
Comparison of the effects of removal of chest hair with not doing so before external defibrillation on transthoracic impedanceDaniel M Sado
Shackleton Department of Anaesthetics, Southampton University Hospital NHS Trust, Southampton, UK
Am J Cardiol 93:98-100. 2004..When the chests of nonhirsute patients were shaved, a decrease in TTI occurred, which was probably related to the creation of low-impedance pathways through skin abrasions...
How good is your defibrillation technique?Daniel M Sado
Department of Oncology, Poole General Hospital, Poole BH15 2JB, UK
J R Soc Med 98:3-6. 2005
New standards for cardiopulmonary resuscitationCharles D Deakin
BMJ 330:685-6. 2005
Local anaesthesia for venous cannulation and arterial blood gas sampling: are doctors using it?Daniel M Sado
Department of Respiratory Medicine, Royal Bournemouth Hospital, Castle Lane East, Bournemouth BH7 7DW, UK
J R Soc Med 98:158-60. 2005..For arterial blood sampling it was used by 60% of anaesthetists and 2% of ward doctors. Previous recommendations to use local anaesthesia seem to have been ignored, and in many instances these procedures are more painful than necessary...
Do we hyperventilate cardiac arrest patients?John F O'Neill
North Hampshire Hospital, NHS Trust, Basingstoke RG24 9NA, UK
Resuscitation 73:82-5. 2007..We observed detailed ventilation variables prospectively during manual ventilation of 12 cardiac arrest patients treated in the emergency department of a UK Hospital...
European Resuscitation Council guidelines for resuscitation 2005. Section 3. Electrical therapies: automated external defibrillators, defibrillation, cardioversion and pacingCharles D Deakin
Resuscitation 67:S25-37. 2005
Pre-hospital fluid therapy in the critically injured patient--a clinical updateEldar Søreide
Division of Acute Care Medicine, Stavanger University Hospital, Stavanger, Norway
Injury 36:1001-10. 2005..This review is intended to help the clinician to balance the pros and cons of fluid therapy in the individual patient...
European Resuscitation Council guidelines for resuscitation 2005. Section 4. Adult advanced life supportJerry P Nolan
Resuscitation 67:S39-86. 2005
Evaluation of telephone CPR advice for adult cardiac arrest patientsCharles D Deakin
Resuscitation Council UK Research Fellow, North Hampshire Hospital NHS Trust, Basingstoke RG24 9NA, UK
Resuscitation 74:63-7. 2007..We evaluated a current telephone protocol (based on 2000 ILCOR guidelines) to assess the effectiveness of verbal CPR instructions...
Scientific knowledge gaps and clinical research priorities for cardiopulmonary resuscitation and emergency cardiovascular care identified during the 2005 International Consensus Conference on ECC [corrected] and CPR science with treatment recommendations:Raúl J Gazmuri
North Chicago VA and Rosalind Franklin University of Medicine and Science, USA
Circulation 116:2501-12. 2007
Scientific knowledge gaps and clinical research priorities for cardiopulmonary resuscitation and emergency cardiovascular care identified during the 2005 International Consensus Conference on ECC and CPR Science with Treatment Recommendations. A consensusRaúl J Gazmuri
Rosalind Franklin University of Medicine and Science, North Chicago Medical Center, Chicago, USA
Resuscitation 75:400-11. 2007
Gastric rupture and laryngeal mask airway: laryngeal mask airway was not likely cause of gastric ruptureJerry P Nolan
BMJ 330:538; author reply 538. 2005
Chest-compression-only or full cardiopulmonary resuscitation?Rudolph W Koster
Lancet 369:1924; author reply 1925. 2007
European Resuscitation Council guidelines for resuscitation 2005. Section 7. Cardiac arrest in special circumstancesJasmeet Soar
Resuscitation 67:S135-70. 2005
