G A Potter

Summary

Affiliation: De Montfort University
Country: UK

Publications

  1. pmc Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism
    Vasilis Androutsopoulos
    Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester, UK
    Breast Cancer Res 10:R39. 2008
  2. pmc The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1
    G A Potter
    Cancer Drug Discovery Group, School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK
    Br J Cancer 86:774-8. 2002
  3. ncbi request reprint Non-haematological solid tumours as surrogate granulocytes: a possible mechanism for metastatic spread
    P C Butler
    Cancer Drug Discovery Group, School of Pharmacy and Biomedical Sciences, De Montfort University, Leicester, UK
    Med Hypotheses 56:625-8. 2001
  4. pmc Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene
    S Sale
    Department of Oncology, University of Leicester, Leicester, UK
    Br J Cancer 90:736-44. 2004
  5. ncbi request reprint Effects of the potential chemopreventive agent DMU-135 on adenoma development in the ApcMin+ mouse
    S Sale
    Cancer Biomarkers and Prevention Group, Department of Cancer Studies, University of Leicester, Leicester, UK
    Invest New Drugs 24:459-64. 2006

Collaborators

Detail Information

Publications5

  1. pmc Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism
    Vasilis Androutsopoulos
    Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester, UK
    Breast Cancer Res 10:R39. 2008
    ..In this study, we aimed to identify a possible mechanism of action for the antiproliferative effect of eupatorin, which can be attributed to CYP1 family-mediated metabolism...
  2. pmc The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1
    G A Potter
    Cancer Drug Discovery Group, School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK
    Br J Cancer 86:774-8. 2002
    ..Importantly this result gives insight into the functional role of CYP1B1 and provides evidence for the concept that CYP1B1 in tumours may be functioning as a growth suppressor enzyme...
  3. ncbi request reprint Non-haematological solid tumours as surrogate granulocytes: a possible mechanism for metastatic spread
    P C Butler
    Cancer Drug Discovery Group, School of Pharmacy and Biomedical Sciences, De Montfort University, Leicester, UK
    Med Hypotheses 56:625-8. 2001
    ....
  4. pmc Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene
    S Sale
    Department of Oncology, University of Leicester, Leicester, UK
    Br J Cancer 90:736-44. 2004
    ....
  5. ncbi request reprint Effects of the potential chemopreventive agent DMU-135 on adenoma development in the ApcMin+ mouse
    S Sale
    Cancer Biomarkers and Prevention Group, Department of Cancer Studies, University of Leicester, Leicester, UK
    Invest New Drugs 24:459-64. 2006
    ..DMU-135 was well tolerated, induced no systemic side-effects and reduced adenoma multiplicity by 46 +/- 18.3% compared to controls (p < 0.001). Further characterisation of this promising chemopreventive agent is required...