K S Cuschieri
- Multiple high risk HPV infections are common in cervical neoplasia and young women in a cervical screening populationK S Cuschieri
Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK
J Clin Pathol 57:68-72. 2004..This study investigated the diversity of multiple HPV types in a routine cervical screening population, and assessed associations with cervical neoplasia...
- The role of human papillomavirus testing in cervical screeningKate S Cuschieri
Specialist Virology Centre, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK
J Clin Virol 32:S34-42. 2005..Due to the diversity of existing cytology-based screening programmes, full cost-effectiveness analyses of HPV testing should be performed and assessed within local contexts...
- Assessment of human papillomavirus mRNA detection over time in cervical specimens collected in liquid based cytology mediumKate S Cuschieri
Specialist Virology Centre, New Royal Infirmary of Edinburgh, 2nd Floor Microbiology, 51 Little France Crescent, Edinburgh EH16 4SA, UK
J Virol Methods 124:211-5. 2005..It is concluded that HPV RNA in routinely collected LBC specimens in PreservCyt can be detected for at least 14 days from sample collection...
- Comparison of the sensitivities of three commercial assays for detection of the high risk HPV types 16, 18 and 45Kate Cuschieri
Scottish HPV Reference Laboratory, Royal Infirmary of Edinburgh, EH16 4SA, United Kingdom Electronic address
J Virol Methods 193:147-50. 2013..This study indicates that mRNA tests had high analytical sensitivity, higher than a well established DNA-test based when using cell lines as target. Implications for clinical application are discussed. ..
- Human papillomavirus mRNA and p16 detection as biomarkers for the improved diagnosis of cervical neoplasiaKate Cuschieri
Specialist Virology Centre, Royal Infirmary of Edinburgh, United Kingdom
Cancer Epidemiol Biomarkers Prev 17:2536-45. 2008..quot;..
- Persistent high risk HPV infection associated with development of cervical neoplasia in a prospective population studyK S Cuschieri
Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, Scotland, UK
J Clin Pathol 58:946-50. 2005..To monitor the association between the course of high risk human papillomavirus (HR-HPV) infection and the development of cervical neoplasia over time, from a baseline of normal cervical cytology...
- Public awareness of human papillomavirusK S Cuschieri
Specialist Virology Centre, Department of Laboratory Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK
J Med Screen 13:201-7. 2006....
- Human Papillomavirus testing for the management of low-grade cervical abnormalities in the UK--Influence of age and testing strategyK S Cuschieri
Specialist Virology Centre, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, United Kingdom
J Clin Virol 38:14-8. 2007..However, several important unresolved issues related to HPV triage remain, two of which are: what type of HPV test should be used and what age group should be targeted...
- Prevalence of human papillomavirus types 16 and 18 in cervical adenocarcinoma and its precursors in Scottish patientsM Tawfik El-Mansi
Department of Pathology, University of Edinburgh, Edinburgh, Scotland, UK
Int J Gynecol Cancer 16:1025-31. 2006....
- Human papillomavirus type specific DNA and RNA persistence--implications for cervical disease progression and monitoringKate S Cuschieri
Specialist Virology Centre, Royal Infirmary of Edinburgh, Edinburgh, Scotland
J Med Virol 73:65-70. 2004....
- Human papilloma virus in squamous carcinoma of the head and neck: a study of cases in south east ScotlandC E Anderson
Division of Pathology, Royal Infirmary of Edinburgh, Edinburgh, UK
J Clin Pathol 60:439-41. 2007..These findings confirm that HPV is likely to be involved in a subset of HNSCC in this population and that successful amplification of HPV nucleic acid is possible even using small amounts of paraffin wax-embedded tissue...
- Cytological recognition of herpes simplex virus infection in bronchoscopic samples from the respiratory tractI Wilkinson
Department of Pathology, Royal Infirmary of Edinburgh, Edinburgh, UK
J R Coll Physicians Edinb 41:26-8. 2011....
- Development of an automated extraction procedure for detection of human papillomavirus DNA in liquid based cytology samplesKate S Cuschieri
Regional Clinical Virology Laboratory, Lothian University Hospitals NHS Trust, The Royal Infirmary of Edinburgh, Little France, 51 Little France Crescent, Edinburgh EH16 4SA, UK
J Virol Methods 107:107-13. 2003..In short, 5 ml of liquid based cytology specimen is recommended for nucleic acid extraction, to allow optimal detection of HPV types in clinical samples while retaining maximum efficiency of the robotic extraction procedure...