Peter Clark

Summary

Country: UK

Publications

  1. ncbi request reprint Cost-effectiveness of screening for the factor V Leiden mutation in pregnant women
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Lancet 359:1919-20. 2002
  2. ncbi request reprint The intercellular adhesion molecule, cadherin-10, is a marker for human prostate luminal epithelial cells that is not expressed in prostate cancer
    Marjorie M Walker
    Division of Investigative Sciences, Department of Histopathology, St Mary s Campus, Imperial College London, London, UK
    Mod Pathol 21:85-95. 2008
  3. ncbi request reprint Prevention and treatment of arterial thrombosis in pregnancy
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee, UK
    Semin Thromb Hemost 29:155-64. 2003
  4. ncbi request reprint Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated by thrombin in human monocytes and THP-1 cells in vitro and in pregnant subjects in vivo
    Peter Clark
    University Department of Obstetrics and Gynecology, Royal Infirmary, Glasgow, Scotland, UK
    Thromb Haemost 89:1043-51. 2003
  5. ncbi request reprint ABO(H) blood groups and pre-eclampsia. A systematic review and meta-analysis
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK
    Thromb Haemost 100:469-74. 2008
  6. doi request reprint Maternal venous thrombosis
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK
    Eur J Obstet Gynecol Reprod Biol 139:3-10. 2008
  7. ncbi request reprint The G-to-T point mutation in codon 34 of the factor XIII gene and the risk of pre-eclampsia
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital Dundee, Glasgow, UK
    Blood Coagul Fibrinolysis 14:155-7. 2003
  8. pmc Quality improvement report: Effect of a formal education programme on safety of transfusions
    P Clark
    Department of Transfusion Medicine, East of Scotland Blood Transfusion Service, Ninewells Hospital, Dundee DD1 9SY, UK
    BMJ 323:1118-20. 2001
  9. ncbi request reprint The Glasgow Outcome, APCR and Lipid (GOAL) Pregnancy Study: significance of pregnancy associated activated protein C resistance
    P Clark
    Department of Haematology, Royal Infirmary, Glasgow, UK
    Thromb Haemost 85:30-5. 2001
  10. ncbi request reprint The GOAL study: a prospective examination of the impact of factor V Leiden and ABO(H) blood groups on haemorrhagic and thrombotic pregnancy outcomes
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee, UK
    Br J Haematol 140:236-40. 2008

Detail Information

Publications22

  1. ncbi request reprint Cost-effectiveness of screening for the factor V Leiden mutation in pregnant women
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Lancet 359:1919-20. 2002
    ..This additional cost would result in prevention of less than one and three vascular events,respectively. Our findings, therefore, suggest that screening of pregnant women for the FVL mutation is not cost-effective...
  2. ncbi request reprint The intercellular adhesion molecule, cadherin-10, is a marker for human prostate luminal epithelial cells that is not expressed in prostate cancer
    Marjorie M Walker
    Division of Investigative Sciences, Department of Histopathology, St Mary s Campus, Imperial College London, London, UK
    Mod Pathol 21:85-95. 2008
    ....
  3. ncbi request reprint Prevention and treatment of arterial thrombosis in pregnancy
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee, UK
    Semin Thromb Hemost 29:155-64. 2003
    ..This review details the management options for prevention of arterial occlusions in these at-risk patients and outlines potential management strategies for arterial occlusions occurring during pregnancy...
  4. ncbi request reprint Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated by thrombin in human monocytes and THP-1 cells in vitro and in pregnant subjects in vivo
    Peter Clark
    University Department of Obstetrics and Gynecology, Royal Infirmary, Glasgow, Scotland, UK
    Thromb Haemost 89:1043-51. 2003
    ....
  5. ncbi request reprint ABO(H) blood groups and pre-eclampsia. A systematic review and meta-analysis
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK
    Thromb Haemost 100:469-74. 2008
    ..In summary, no clear association between any ABO(H) blood group and pre-eclampsia can be made from available studies. However, existing data does not allow exclusion of an effect limited to those expressing the least O(H) antigen...
  6. doi request reprint Maternal venous thrombosis
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK
    Eur J Obstet Gynecol Reprod Biol 139:3-10. 2008
    ..This review details the pathophysiology of venous thromboembolism in pregnancy and outlines the appropriate risk assessment, prophylaxis and management, which is required to minimise the burden of venous thrombosis on maternal health...
  7. ncbi request reprint The G-to-T point mutation in codon 34 of the factor XIII gene and the risk of pre-eclampsia
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital Dundee, Glasgow, UK
    Blood Coagul Fibrinolysis 14:155-7. 2003
    ..7 (CI95 0.4-1.1). We conclude that the presence of leucine at this site is not associated with a protection against pre-eclampsia to the magnitude of that reported in other thrombotic disease...
  8. pmc Quality improvement report: Effect of a formal education programme on safety of transfusions
    P Clark
    Department of Transfusion Medicine, East of Scotland Blood Transfusion Service, Ninewells Hospital, Dundee DD1 9SY, UK
    BMJ 323:1118-20. 2001
    ..Failure of correct identification and insufficient monitoring of patients receiving transfusions continue to be appreciable and avoidable causes of morbidity and mortality...
  9. ncbi request reprint The Glasgow Outcome, APCR and Lipid (GOAL) Pregnancy Study: significance of pregnancy associated activated protein C resistance
    P Clark
    Department of Haematology, Royal Infirmary, Glasgow, UK
    Thromb Haemost 85:30-5. 2001
    ..Higher APC:SRs were observed in blood group O subjects and smokers. An inverse relationship of the APC:SR with age, diastolic blood pressure and total serum cholesterol was observed...
  10. ncbi request reprint The GOAL study: a prospective examination of the impact of factor V Leiden and ABO(H) blood groups on haemorrhagic and thrombotic pregnancy outcomes
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee, UK
    Br J Haematol 140:236-40. 2008
    ..We neither confirmed the protective effect of FVL on pregnancy-related blood loss reported in previous smaller studies, nor did we find the increased risk of some vascular complications reported in retrospective studies...
  11. ncbi request reprint Changes of hemostasis variables during pregnancy
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee, United Kingdom
    Semin Vasc Med 3:13-24. 2003
    ....
  12. ncbi request reprint Short- and long-term changes in plasma inflammatory markers associated with preeclampsia
    Dilys J Freeman
    Division of Developmental Medicine, University of Glasgow, Glasgow, United Kingdom
    Hypertension 44:708-14. 2004
    ..In conclusion, preeclampsia is associated with short- and long-term changes in inflammatory status...
  13. ncbi request reprint Screening for thrombophilia in high-risk situations: a meta-analysis and cost-effectiveness analysis
    Olivia Wu
    Division of Developmental Medicine, University of Glasgow, Glasgow, UK
    Br J Haematol 131:80-90. 2005
    ..Selective thrombophilia screening based on previous personal and/or family history of venous thromboembolism was more cost-effective than universal screening in all the patient groups evaluated...
  14. doi request reprint Venous thrombosis prevention - more than just guidelines
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital, Dundee, UK
    Br J Haematol 149:50-4. 2010
    ....
  15. doi request reprint SPIN (Scottish Pregnancy Intervention) study: a multicenter, randomized controlled trial of low-molecular-weight heparin and low-dose aspirin in women with recurrent miscarriage
    Peter Clark
    Department of Transfusion Medicine, Ninewells Hospital and Medical School, Dundee, UK
    Blood 115:4162-7. 2010
    ..The trial was registered at http://www.controlled-trials.com as ISRCTN06774126...
  16. doi request reprint ABO blood groups and thrombosis: a causal association, but is there value in screening?
    Peter Clark
    Department of Transfusion Medicine, East of Scotland Blood Transfusion Centre, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK
    Future Cardiol 7:191-201. 2011
    ..The potential mechanisms whereby blood group influences thrombosis, the limitations of current evidence and the current and future role of blood groups in identifying those at risk of arterial and venous disease is discussed...
  17. ncbi request reprint An audit of the investigation and use of anti-D immunoglobulin prophylaxis in Tayside
    I Rennie
    East of Scotland Blood Transfusion Service, Ninewells Hospital, Dundee
    Health Bull (Edinb) 59:150-4. 2001
    ..This has allowed the introduction of internal laboratory referral for FMH assessment. This has allowed accurate knowledge on the possible occurrence of FMH at delivery, but has not had a significant impact on antenatal events...
  18. ncbi request reprint Antenatal waist circumference and hypertension risk
    N Sattar
    Department of Pathological Biochemistry, Glasgow Royal Infirmary University NHS Trust, Glasgow, Scotland, United Kingdom
    Obstet Gynecol 97:268-71. 2001
    ..To assess whether waist circumference at the first antenatal visit predicts risk of developing hypertension later in pregnancy...
  19. ncbi request reprint Effect of supplementation with folic acid throughout pregnancy on plasma homocysteine concentration
    J Ellison
    University Department of Obstetrics and Gynaecology, Royal Infirmary, Glasgow, UK
    Thromb Res 114:25-7. 2004
  20. ncbi request reprint Interaction of the protein C/protein S anticoagulant system, the endothelium and pregnancy
    P Clark
    Department of Haematology, Royal Infirmary, Glasgow, UK
    Blood Rev 13:127-46. 1999
    ..The changes which characterize normal and complicated pregnancies are outlined and the evidence for the impact of heritable and acquired disorders of the protein C/protein S system on pre-eclampsia and fetal loss are discussed...
  21. ncbi request reprint Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study
    Olivia Wu
    Department of Obstetrics and Gynaecology, University of Glasgow, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER, UK
    Thromb Haemost 94:17-25. 2005
    ..However, further studies are required to establish with greater confidence the associations of these, and other, thrombophilias with venous thromboembolism among hormone users...
  22. ncbi request reprint Lymphocyte transcellular migration occurs through recruitment of endothelial ICAM-1 to caveola- and F-actin-rich domains
    Jaime Millan
    Ludwig Institute for Cancer Research, Royal Free and University College School of Medicine, 91 Riding House Street, London W1W 7BS, UK
    Nat Cell Biol 8:113-23. 2006
    ....