Research Topics
Species | J V PatelSummaryAffiliation: City Hospital Country: UK Publications
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Publications
Evaluation of B-type natriuretic peptide for validation of a heart failure register in primary careGurbir S Bhatia
Department of Cardiology, Sandwell and West Birmingham Hospitals NHS Trust, Lyndon, West Bromwich, UK
BMC Cardiovasc Disord 7:23. 2007..We sought to determine the accuracy of a heart failure register in a single primary care practice, and to examine the usefulness of b-type (or brain) natriuretic peptide (BNP) assay for this purpose...
Role of metabolically active hormones in the insulin resistance associated with short-term glucocorticoid treatmentJeetesh V Patel
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine and Sandwell Medical Research Unit, Sandwell and West Birmingham Hospitals NHS Trust, West Midlands, UK
J Negat Results Biomed 5:14. 2006..Little is known about the effects of short-term glucocorticoid treatment on levels of these hormones...
Widening access to cardiovascular healthcare: community screening among ethnic minorities in inner-city Britain - the Healthy Hearts ProjectJeetesh V Patel
Sandwell Medical Research Unit, Sandwell General Hospital, Sandwell and West Birmingham Hospitals NHS Trust, UK
BMC Health Serv Res 7:192. 2007..The key anticipated outcomes were the numbers of participants from various ethnic backgrounds attending the health screening events and the prevalence of known and undiagnosed CVD risk within ethnic groups...
Ethnic differences in myocardial infarction in patients with hypertension: effects of diabetes mellitusJ V Patel
Sandwell General Hospital, West Bromwich, B71 4HJ, UK
QJM 101:231-6. 2008..This has been attributed to some specifically Asian susceptibility factor...
Efficacy, safety and LDL-C goal attainment of ezetimibe 10 mg-simvastatin 20 mg vs. placebo-simvastatin 20 mg in UK-based adults with coronary heart disease and hypercholesterolaemiaJ V Patel
Sandwell Medical Research Unit, Sandwell and West Birmingham Hospitals NHS Trust, West Bromwich, UK
Int J Clin Pract 60:914-21. 2006....
Omega-3 polyunsaturated fatty acids: a necessity for a comprehensive secondary prevention strategyJeetesh V Patel
Haemostasis, Thrombosis and Vascular Biology Unit, University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, England, UK
Vasc Health Risk Manag 5:801-10. 2009..We suggest that the available evidence supports the use of omega-3 supplementation as part of the comprehensive secondary care package for post-MI patients...
Triglycerides and small dense low density lipoprotein in the discrimination of coronary heart disease risk in South Asian populationsJ V Patel
Clinical Epidemiology and Cardiovascular Medicine Group, University Department of Medicine, University of Manchester, UK
Atherosclerosis 209:579-84. 2010..Coronary heart disease (CHD) is exceptionally prevalent amongst globally dispersed migrant groups originating from the Indian subcontinent, but the contribution of dyslipidaemia to their increased risk remains poorly defined...
Circulating serum adiponectin levels in patients with coronary artery disease: relationship to atherosclerotic burden and cardiac functionJ V Patel
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
J Intern Med 264:593-8. 2008..We hypothesized that plasma adiponectin would relate to indices of coronary artery disease severity (coronary atheroma scores, CAS), ejection fraction (EF) and regional wall motion abnormalities (RWMA) therein...
Secular trends in the cardiovascular risk profile and mortality of stroke admissions in an inner city, multiethnic population in the United Kingdom (1997-2005)A Gunarathne
University Department of Medicine, City Hospital, Birmingham, UK
J Hum Hypertens 22:18-23. 2008..The reduced decline in stroke admissions and 30-day survival of stroke in South Asians in recent years warrants further investigation and highlights the importance of a targeted health-care approach in the migrant ethnic minorities...
Increased 5-year mortality in the migrant South Asian stroke patients with diabetes mellitus in the United Kingdom: the West Birmingham Stroke ProjectA Gunarathne
University Department of Medicine, City Hospital, Birmingham, England, UK
Int J Clin Pract 62:197-201. 2008..Because of the paucity of data in this area, we investigated the magnitude and impact of risk from cardiovascular comorbidities on survival amongst South Asian stroke patients...
Elevated lipoprotein (a) and apolipoprotein B to AI ratio in South Asian patients with ischaemic strokeK M Sharobeem
Department of Geriatric Medicine, Sandwell and West Birmingham Hospitals NHS Trust, Edgbaston, Birmingham, UK
Int J Clin Pract 61:1824-8. 2007..However, little is known about the dyslipidaemia associated with stroke in South Asians. In particular, the highly atherogenic lipoprotein (a) [Lp(a)] and high apolipoprotein (Apo) B to AI ratio are emerging risk factors for CVD...
Impact of migration on coronary heart disease risk factors: comparison of Gujaratis in Britain and their contemporaries in villages of origin in IndiaJ V Patel
University Department of Medicine, University of Manchester, Division of Cardiovascular and Endocrine Science, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK
Atherosclerosis 185:297-306. 2006..Strategies to improve nutrition and to identify and treat cardiovascular risk factors such as dyslipidaemia and hypertension are urgently required...
Circulating biomarkers of angiogenesis as indicators of left ventricular systolic dysfunction amongst patients with coronary artery diseaseJ V Patel
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
J Intern Med 265:562-7. 2009..We also evaluated the specificity of angiogenic 'biomarkers' in their detection of LVSD [ejection fraction (EF) <40%] amongst CAD patients...
Omega-3 polyunsaturated acids and cardiovascular disease: notable ethnic differences or unfulfilled promise?J V Patel
Haemostasis, Thrombosis and Vascular Biology Unit, University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, England, UK
J Thromb Haemost 8:2095-104. 2010..Future epidemiological research into the efficacy of omega-3 PUFA in cardiovascular disease should consider the influence of ethnicity...
Prognostic value of plasma soluble P-selectin and von Willebrand factor as indices of platelet activation and endothelial damage/dysfunction in high-risk patients with hypertension: a sub-study of the Anglo-Scandinavian Cardiac Outcomes TrialG I Varughese
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
J Intern Med 261:384-91. 2007....
Adiponectin and hypertension: a putative link between adipocyte function and atherosclerotic risk?J V Patel
Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
J Hum Hypertens 21:1-4. 2007
Short-term effects of screening for cardiovascular risk in the deaf community: a pilot studyJ V Patel
Sandwell Medical Research Unit, Sandwell and West Birmingham Hospitals NHS Trust, West Midlands B17 4HJ, UK
Cardiol Res Pract 2011:493546. 2011..The reasons for this are likely to relate to the design and delivery of health promotion to Deaf people, which deserves further study...
Effects of coronary artery disease and percutaneous intervention on the cardiac metabolism of nonesterified fatty acids and insulin: Implications of diabetes mellitusR J Jaumdally
University Department of Medicine, City Hospital, Birmingham England, UK
J Intern Med 265:689-97. 2009..We also studied the metabolic cardiac response following percutaneous coronary intervention (PCI)...
Blood pressure control in the setting of diabetes mellitus: new targets, new hope for improvement?G I Varughese
University Department of Medicine, City Hospital, Birmingham, UK
J Hum Hypertens 20:635-7. 2006
Should oral glucose tolerance testing be mandatory following acute myocardial infarction?S Jessani
University Department of Medicine, City Hospital, Birmingham, UK
Int J Clin Pract 61:680-3. 2007..The false reassurance of a normal FPG denies a significant proportion of undiagnosed diabetics the chance of early treatment. The importance of OGTT in the diagnostic work up of this vulnerable high-risk group cannot be over-emphasised...
Reactive oxygen species production by circulating monocytes: insights from pathophysiology to clinical hypertensionH S Lim
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
J Hum Hypertens 20:307-9. 2006
Raised leptin concentrations among South Asian patients with chronic heart failureJeetesh V Patel
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, United Kingdom
Int J Cardiol 122:34-40. 2007..However, little is known about ethnic variations of adipocytokines amongst CHF patients, in particular South Asians, who are at an increased risk of CHF...
Effects of omega-3 polyunsaturated fatty acids on metabolically active hormones in patients post-myocardial infarctionJeetesh V Patel
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, UK
Int J Cardiol 115:42-5. 2007..The effects of omega-3 PUFA on markers of energy homeostasis among post-MI patients are unclear...
Angiopoietin-2 levels as a biomarker of cardiovascular risk in patients with hypertensionJeetesh V Patel
University Department of Medicine, City Hospital, Birmingham, UK
Ann Med 40:215-22. 2008..We hypothesized that raised levels of angiopoietin (Ang)-1 and -2 would predict events in patients with hypertension treated for CVD...
Hypertension and genes: perspectives from this journalJ Chackathayil
Sandwell Medical Research Unit, Sandwell Hospital, West Bromwich, UK
J Hum Hypertens 21:851-3. 2007
Angiogenin: a review of the pathophysiology and potential clinical applicationsA Tello-Montoliu
Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
J Thromb Haemost 4:1864-74. 2006....
Abnormal soluble CD40 ligand and C-reactive protein concentrations in hypertension: relationship to indices of angiogenesisJeetesh V Patel
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
J Hypertens 24:117-21. 2006..The interaction between sCD40L and angiogenesis may contribute to the pathophysiology of CVD in hypertension...
Circulating levels of adiponectin, leptin, and tumour necrosis factor alpha in hypertensionJeetesh V Patel
Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, England, UK
Ann Med 41:291-300. 2009..The pragmatic utility of these 'adipocytokines' in the clinical setting of hypertension is unclear, and we hypothesized a relationship of circulating adipocytokines to hypertension, and associated cardiovascular morbidity...
Ischemic stroke in South Asians: a review of the epidemiology, pathophysiology, and ethnicity-related clinical featuresAshan Gunarathne
University Department of Medicine, City Hospital, Birmingham, B18 7QH, UK
Stroke 40:e415-23. 2009..The aim of this review is to present a comprehensive and systematic overview of the available literature relating to ischemic stroke among South Asian populations identifying distinct features of stroke epidemiology in this group...
Candidate circulating biomarkers for the cardiovascular disease continuumOlena Dotsenko
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, England
Curr Pharm Des 14:2445-61. 2008..Such an application of biomarkers to aid clinical risk assessment would be important in our efforts to improve risk stratification of subjects at risk of cardiovascular events...
Efficacy and safety of atorvastatin in South Asian patients with dyslipidemia: an open label noncomparative pilot studyJeetesh V Patel
Sandwell and West Birmingham Hospitals NHS Trust, West Bromwich, UK
Vasc Health Risk Manag 1:351-6. 2005..Statin therapy for high-risk South Asian individuals is likely to benefit CHD outcomes, although further and larger prospective trials are required...
Premature coronary artery disease: an inferred cardiovascular variant or a South Asian genetic disorder?Jeetesh V Patel
Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
Thromb Haemost 99:991-2. 2008
Apolipoproteins in the discrimination of atherosclerotic burden and cardiac function in patients with stable coronary artery diseaseJeetesh V Patel
Haemostasis Thrombosis and Vascular Biology Unit, University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK
Eur J Heart Fail 12:254-9. 2010..To compare the performance of apolipoproteins (Apo) and oxidized LDL against routine clinical lipid profiles in the discrimination of atherosclerotic burden and cardiac function in stable coronary artery disease (CAD) patients...
Plasma matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-2, and CD40 ligand levels in patients with stable coronary artery diseaseMuzahir H Tayebjee
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, United Kingdom
Am J Cardiol 96:339-45. 2005..The gender difference in high-sensitivity C-reactive protein and MMP-9 levels may provide insight into the pathophysiology of coronary artery disease in men and women, and further studies are warranted to explore this potential link...
Novel concepts of statin therapy for cardiovascular risk reduction in hypertensionGeorge I Varughese
Department of Cardiology and Vascular Medicine, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham B18 7QH, England
Curr Pharm Des 12:1593-609. 2006..In this article, the novel pleiotropic and conventional mechanisms of statins, and clinical data of statin therapy in patients with hypertension are reviewed...
Is soluble CD40 ligand a mediator of angiogenesis in patients with coronary artery disease?Hoong Sern Lim
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, England, UK
Thromb Res 122:307-13. 2008..We hypothesised raised plasma levels of VEGF and Ang-2, but not Ang-1, and correlations with raised sCD40L levels and CAD severity/collateralisation in patients with CAD...
Elevated angiogenin levels in chronic heart failureJeetesh V Patel
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
Ann Med 40:474-9. 2008....
Plasma indices of endothelial and platelet activation in Rheumatoid Disease: relationship to cardiovascular co-morbidityGurbir S Bhatia
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B187QH, England UK
Int J Cardiol 134:97-103. 2009..We sought to investigate whether abnormalities of endothelial function and platelet activation in patients with established RD were related to co-morbid cardiovascular risk factors...
Measurement of stiffness index by digital volume pulse analysis technique: clinical utility in cardiovascular disease risk stratificationAshan Gunarathne
University Department of Medicine, City Hospital, Birmingham, UK
Am J Hypertens 21:866-72. 2008..The utility of stiffness index (SI) derived from digital volume pulse (DVP) analysis in CVD risk screening is not established...
Impact of mean arterial blood pressure on higher arterial stiffness indices in South Asians compared to white EuropeansAshan Gunarathne
University Department of Medicine, City Hospital, Birmingham, UK
J Hypertens 26:1420-6. 2008....
Effects of blood pressure on the prothrombotic risk in 1235 patients with non-valvular atrial fibrillationGeorge I Varughese
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
Heart 93:495-9. 2007..However, the effect of hypertension on the levels of these indices in the setting of atrial fibrillation, and whether increasing severity of hypertension presents an additive prothrombotic risk, is unclear...
Nonesterified fatty acids as mediators of glucose intolerance in Indian Asian populationsJeetesh V Patel
University Dept. of Medicine, Manchester Royal Infirmary, Manchester M13 9WL, U.K
Diabetes Care 28:1505-7. 2005
Comparison of brain natriuretic peptide and left ventricular diastolic function determined by tissue Doppler in patients with diabetes mellitus, patients with hypertension without diabetes, and in healthy subjectsHoong Sern Lim
Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, United Kingdom
Am J Cardiol 95:905-8. 2005..A "package of care" of glycemic control and cardiovascular risk management was not associated with reduction in BNP levels...
Effects of short-term glucocorticoids on cardiovascular biomarkersDaniel J Brotman
Department of General Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Clin Endocrinol Metab 90:3202-8. 2005..However, the short-term effects of glucocorticoids on other cardiovascular risk factors remain incompletely characterized...
Metabolic syndrome: a definition in progressHoong Sern Lim
Circulation 110:e35; author reply e35. 2004
